Haferlach
Claudia Haferlach, Inning DE
Patent application number | Description | Published |
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20120252690 | METHOD FOR DETECTING BALANCED CHROMOSOMAL ABERRATIONS IN A GENOME - The present disclosure provides methods and systems for the capture and enrichment of target nucleic acids and analysis of the enriched target nucleic acids for detecting balanced chromosomal aberrations including translocations and inversions. The present disclosure provides for the enrichment of targeted sequences in a format whereby one fusion partner gene on a capturing platform is represented to allow subsequent sequencing of chimeric nucleic acids (i.e., nucleic acid strands that carry information on different DNA regions of a genome). Such a design enables identification of novel fusion partner genes occurring as a result of a chromosomal translocation or inversion. | 10-04-2012 |
20150024948 | METHOD FOR DETECTING BALANCED CHROMOSOMAL ABERRATIONS IN A GENOME - The present disclosure provides methods and systems for the capture and enrichment of target nucleic acids and analysis of the enriched target nucleic acids for detecting balanced chromosomal aberrations including translocations and inversions. The present disclosure provides for the enrichment of targeted sequences in a format whereby one fusion partner gene on a capturing platform is represented to allow subsequent sequencing of chimeric nucleic acids (i.e., nucleic acid strands that carry information on different DNA regions of a genome). Such a design enables identification of novel fusion partner genes occurring as a result of a chromosomal translocation or inversion. | 01-22-2015 |
Torsten Haferlach, Munich DE
Patent application number | Description | Published |
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20090118132 | Classification of Acute Myeloid Leukemia - The present invention relates to rapid and reliable approaches to leukemia prognostication. In addition to methods, the invention also provides related kits and systems. | 05-07-2009 |
Torsten Haferlach, Inning DE
Patent application number | Description | Published |
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20120252690 | METHOD FOR DETECTING BALANCED CHROMOSOMAL ABERRATIONS IN A GENOME - The present disclosure provides methods and systems for the capture and enrichment of target nucleic acids and analysis of the enriched target nucleic acids for detecting balanced chromosomal aberrations including translocations and inversions. The present disclosure provides for the enrichment of targeted sequences in a format whereby one fusion partner gene on a capturing platform is represented to allow subsequent sequencing of chimeric nucleic acids (i.e., nucleic acid strands that carry information on different DNA regions of a genome). Such a design enables identification of novel fusion partner genes occurring as a result of a chromosomal translocation or inversion. | 10-04-2012 |
20150024948 | METHOD FOR DETECTING BALANCED CHROMOSOMAL ABERRATIONS IN A GENOME - The present disclosure provides methods and systems for the capture and enrichment of target nucleic acids and analysis of the enriched target nucleic acids for detecting balanced chromosomal aberrations including translocations and inversions. The present disclosure provides for the enrichment of targeted sequences in a format whereby one fusion partner gene on a capturing platform is represented to allow subsequent sequencing of chimeric nucleic acids (i.e., nucleic acid strands that carry information on different DNA regions of a genome). Such a design enables identification of novel fusion partner genes occurring as a result of a chromosomal translocation or inversion. | 01-22-2015 |