Haeggstrom

Edward Haeggstrom, Helsinki FI

Patent application number	Description	Published
20110261347	Method for interferometric detection of surfaces - The invention relates to a method for imaging a microfabricated device comprising at least one oscillating component. The method comprises stroboscopically illuminating in an interferometric setup said component in synchronized relationship with the excitation of the device, and detecting interference light in synchronized relationship with the illumination and excitation. According to the invention the component is illuminated at a wavelength band which is at least partly transmissible by the component, and the positions of at least two separate surfaces of the component of interest are determined based on the interference light detected at least at two temporal phases of excitation of the device. The invention provides an efficient method for in-depth characterization of micromechanical structures that provide only one-sided access during operation.	10-27-2011

Patent application number	Description	Published
20100216113	Methods - A method for selecting or designing a compound expected to modulate the activity of Leukotriene C4 synthase (LTC4S), the method comprising the step of using molecular modelling means to select or design a compound that is predicted to interact with the catalytic site or a substrate binding region of LTC4S, wherein a three-dimensional structure of at least a part of the catalytic site or a substrate binding region of LTC4S is compared with a three-dimensional structure of a compound, and a compound that is predicted to interact with the said catalytic site or substrate binding region is selected. The selected compound may be predicted to bind to at least a part of a region of the structure termed the “GSH substrate binding cavity” (formed by residues including residues Arg51, Arg30, Arg104, Gln53, Asn55, Glu58, Tyr59, Tyr93, Tyr97, Ile27, Pro37, Leu108 of full length human LTC4S, or equivalent residues); the “lipophilic substrate binding crevice” (formed by residues including Ala20, Leu24, Ile27, Tyr59, Trp116, Ala112, Leu115, Leu108, Tyr109, Leu62, Val119, Thr66, Vall6 and Leu17, or equivalent residues); or the “catalytic site” (formed by residues including Arg104 or Arg31, or equivalent residues).	08-26-2010

Patent application number	Description	Published
20100200077	PLUMBING FIXTURE TRIM SNAP CONNECT - A plumbing fixture trim snap connect comprises a faucet handle assembly and a base assembly. The faucet handle assembly includes an escutcheon bearing upper and lower internal tabs, freely rotatable around a faucet handle. The base assembly includes a base seat on which a spring and retainer are maintained in an upwardly biased position. The seat includes a groove and helical cut, and the retainer includes indents in its surface to accommodate the upper and lower tabs of the escutcheon. By pushing the escutcheon down atop the base assembly and rotating the escutcheon relative to the base assembly, the apparatus can be assembled. Disassembly can be accomplished simply by rotating the escutcheon in the opposite direction.	08-12-2010