| Patent application number | Description | Published |
| 20080305049 | Mri Contrast Agents for Diagnosis and Prognosis of Tumors - The invention relates to bifunctional conjugates comprising a receptor ligand moiety and a metal binding moiety and complexes thereof with paramagnetic lanthanide or transition metals, and to the use of the metal complexes as contrast agents in magnetic resonance imaging (MRI) of tumors and other abnormalities. | 12-11-2008 |
| 20090028405 | Three Time Point Lung Cancer Detection, Diagnosis and Assessment of Prognosis - malignancy classification method and medium for classifying a region of lung tissue are disclosed. The classifying includes: setting time points T | 01-29-2009 |
| 20090076759 | APPARATUS FOR MONITORING A SYSTEM WITH TIME IN SPACE AND METHOD THEREFOR - Apparatus and method for monitoring a system in which a fluid flows and which is characterized by a change in the system with time in space. A preselected place in the system is monitored to collect data at two or more time points correlated to a system event. The data is indicative of a system parameter that varies with time as a function of at least two variables related to system wash-in and wash-out behavior. A calibration map is made on a calculated basis with each pixel or voxel representative of a color hue indicative of wash-out behavior and a color intensity indicative of wash-in behavior. The calibration map serves as a criteria for selecting the time points. Software and a data processing system are provided to develop a color coded output map. The calibration map, the color coded output map and image of the preselected place are also novel implementations. | 03-19-2009 |
| 20090264734 | APPARATUS FOR MONITORING A SYSTEM PRESSURE IN SPACE WITH TIME AND METHOD FOR ASSESSING DRUG DELIVERY AND RESISTANCE TO THERAPY AND PRODUCT - A method, apparatus and a computer readable medium containing executable instructions for monitoring a system pressure within a mammal, human or animal, via a tracer/contrast agent, in space in time for determining non-invasively actual interstitial fluid pressure and/or concentration of the tracer/contrast agent. Further, an imaging method, an apparatus and a product for non-invasive mapping of actual interstitial fluid pressure and/or a tracer/contrast agent concentration for assessing drug delivery and resistance to therapy of a tumor or organ within a mammal, to suppress or reduce pressure in a tumor or organ and to control the delivery of drugs to a tumor or organ. | 10-22-2009 |
| 20100092058 | METHOD FOR OBTAINING SPATIAL IMAGES THROUGH MRI AND PROCESSING THE RESULTING SPATIAL IMAGES AND PRODUCT - A method for recording a set of MRI images of a tissue pixel by pixel that evolve with time in a specific manner described by a function; processing the recorded MRI images by aggregating the pixels thereof according to a preselected aspect of time behavior; best fitting the aggregated pixels to a predetermined pixel function to obtain the parameters of the function; and presenting the parameters visually. A computer readable medium containing executable program instructions for carrying out the method. | 04-15-2010 |
| 20100142786 | METHOD AND APPARATUS FOR COMPUTER-AIDED DIAGNOSIS OF CANCER AND PRODUCT - Method and apparatus performing dynamic contrast-enhanced-magnetic resonance imaging on tissue to obtain a plurality of datasets of images. Principal component analysis is performed on each dataset to obtain a covariance matrix and its corresponding eigenvalues and eigenvectors and produce a common base of eigenvectors. The dominant eigenvectors that are not associated with instrumental and random noise, commonly the 2 | 06-10-2010 |
| 20110038521 | METHOD AND APPARATUS FOR DUCTAL TUBE TRACKING IMAGING FOR BREAST CANCER DETECTION AND DIAGNOSIS, AND PRODUCT - A method apparatus and computer product for imaging a human breast to map the breast ductal tree is disclosed. First, a breast is diffusion tensor imaged with high spatial resolution. Then the breast ductal tree is tracked using a protocol for breast based on echo-planar imaging (EPI) diffusion designed for optimizing diffusion weightings (b values), number of non-collinear directions for tensor calculations, diffusion, echo and repetition times, spatial resolution, signal to noise, scanning time and a sequence for fat suppression. The diffusion tensor is calculated by a non-linear best fit algorithm and then diagonalized with principal component analysis to three eigen vectors and their corresponding eigen values. A vector field map is obtained for tracking of breast ducts of the ductal trees along the direction of the 1 | 02-17-2011 |
| 20110093231 | APPARATUS FOR MONITORING A SYSTEM WITH TIME IN SPACE AND METHOD THEREFOR - Apparatus and method for monitoring a system in which a fluid flows and which is characterized by a change in the system with time in space. A preselected place in the system is monitored to collect data at two or more time points correlated to a system event. The data is indicative of a system parameter that varies with time as a function of at least two variables related to system wash-in and wash-out behavior. A calibration map is made on a calculated basis with each pixel or voxel representative of a color hue indicative of wash-out behavior and a color intensity indicative of wash-in behavior. The calibration map serves as a criteria for selecting the time points. Software and a data processing system are provided to develop a color coded output map. The calibration map, the color coded output map and image of the preselected place are also novel implementations. | 04-21-2011 |