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Haber, US

Carol Haber, Salisbury, NH US

Patent application numberDescriptionPublished
20090012020Inhibiting formation of atherosclerotic lesions - The invention features a method of inhibiting formation of atherosclerotic lesions by administering to a mammal, e.g., a human patient who has been identified as suffering from or at risk of developing atherosclerosis, a compound that reduces expression or activity of AFABP.01-08-2009

Constance Haber, Marrysville, PA US

Patent application numberDescriptionPublished
20110178581Therapeutic Methods Using Electromagnetic Radiation - This invention provides methods for treating a variety of disorders using localized electromagnetic radiation directed at excitable tissues, including nerves, muscles and blood vessels. By controlling the wavelength, the wavelength bandpass, pulse duration, intensity, pulse frequency, and/or variations of those characteristics over time, and by selecting sites of exposure to electromagnetic radiation, improvements in the function of different tissues and organs can be provided. By monitoring physiological variables such as muscle tone and activity, temperature gradients, surface electromyography, blood flow and others, the practitioner can optimize a therapeutic regimen suited for the individual patient.07-21-2011

Daniel A. Haber, Chestnut Hill, MA US

Patent application numberDescriptionPublished
20080207615Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments - The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.08-28-2008
20080220424Method for Predicting Responsiveness to Drugs - The present invention provides a novel method to determine the likelihood of effectiveness of a treatment in an individual affected with or at risk for developing cancer. The method involves detecting the presence or absence of Met amplification in an individual. The presence of Met amplification indicates that a Met targeting treatment is likely to be effective. Preferably, the Met targeting treatment is PHA-665752 or PF-02341066. In addition, the present methods allow for the detection of cancer in an individual, wherein the presence of Met amplification indicates that cancer is present and further that it will be treatable, namely with a Met targeting treatment.09-11-2008
20080234264Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments - The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.09-25-2008
20100087482Method for Treating Gefitinib Resistant Cancer - The present invention is directed to methods for the treatment of gefitinib and/or erlotinib resistant cancer. An individual with cancer is monitored for cancer progression following treatment with gefitinib and/or erlotinib. Progression of the cancer is indicative that the cancer is resistant to gefitinib and/or erlotinib. Once progression of cancer is noted, the subject is administered a pharmaceutical composition comprising an irreversible epidermal growth factor receptor (EGFR) inhibitor. In preferred embodiments, the irreversible EGFR inhibitor is EKB-569, HKI-272 and HKI-357.04-08-2010
20110306043DEVICES AND METHODS FOR ENRICHMENT AND ALTERATION OF CIRCULATING TUMOR CELLS AND OTHER PARTICLES - The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.12-15-2011

Patent applications by Daniel A. Haber, Chestnut Hill, MA US

Edgar Haber, Salisbury, NH US

Patent application numberDescriptionPublished
20090012020Inhibiting formation of atherosclerotic lesions - The invention features a method of inhibiting formation of atherosclerotic lesions by administering to a mammal, e.g., a human patient who has been identified as suffering from or at risk of developing atherosclerosis, a compound that reduces expression or activity of AFABP.01-08-2009

Elliot J. Haber, Fall City, WA US

Patent application numberDescriptionPublished
20120047461Reputation-Based Safe Access User Experience - Reputation-based resource lookup may include determining the reputation of resources that are to be accessed. Based on the reputation of the resource, a user experience is provided. Protection can be provided from known and suspicious resources, by providing warnings, such as unique graphical visual warnings and textual messages. Furthermore, additional information may be provided as to the desired resource. A user may be further required to go through several pages or asked various questions before accessing a resource.02-23-2012

Elliot Jeb Haber, Fall City, WA US

Patent application numberDescriptionPublished
20090187442FEEDBACK AUGMENTED OBJECT REPUTATION SERVICE - Described herein is technology for, among other things, implementing a feedback augmented optic reputation service. A request for an object reputation is received from a user, and in response to the request, a reputation generation service is accessed to determine a value for the object reputation. The value for the object reputation is returned to the user. Feedback is solicited from the user when displaying information regarding the object reputation. Feedback regarding the returned object reputation is received from the user, and a knowledge base describing the object reputation is updated in consideration of the feedback. An updated object reputation is returned in response to a subsequent request.07-23-2009

Elliott J. Haber, Fall City, WA US

Patent application numberDescriptionPublished
20110145435Reputation Based Redirection Service - A reputation based redirection service is usable to build URL wrappers for un-trusted and unknown URLs. Such URL wrappers can be used to protect Web users by, for example, redirecting traffic to interstitial Web pages. Additionally, reputation decisions can be made by the service to further protect users from malicious URLs.06-16-2011

Elliott Jeb Haber, Fall City, WA US

Patent application numberDescriptionPublished
20100162391Online Risk Mitigation - Online risk mitigation techniques are described. In an implementation, a service is queried for a reputation associated with an object from an online source in response to selection of the object. A backup of a client that is to receive the object is stored prior to obtaining the object when the reputation does not meet a threshold reputation level.06-24-2010
20120066346REPUTATION CHECKING OBTAINED FILES - A Web browser of a computing device downloads or otherwise obtains a file. File information identifying the file is obtained and is sent to a remote reputation service. Client information identifying aspects of the computing device can also optionally be sent to the remote reputation service. In response to the file information (and optionally client information), a reputation indication for the file is received from the remote reputation service. A user interface for the Web browser to present at the computing device is determined, based at least in part on the reputation indication, and presented at the computing device.03-15-2012

Patent applications by Elliott Jeb Haber, Fall City, WA US

Jeff Haber US

Patent application numberDescriptionPublished
20100145795Directing internet shopping traffic and tracking revenues generated as a result thereof - A system having a client, a host server, a sponsor server, and a video server, which are all interconnected via the Internet and which operate seamlessly together in order to provide video content to an end user at the client and allow the end user at the client to purchase products and/or services from the sponsor that are featured in the video content provided by the video server. As the user views video content on his or her computer, images associated with segments of the content are periodically provided in conjunction with the video content. Each image contains an image map, which defines areas in the image. Each defined area is associated with a product which is displayed in that area of the image. Each defined area is also associated with an anchored hyperlink which links to web content from a sponsor server. The web content includes product information for that particular product featured in that area of the image. Accordingly, by selecting an item in the image, product information is retrieved from a sponsor server and provided to the user so he or she may purchase the product seen in the video content.06-10-2010

Jerome Haber, Weston, MA US

Patent application numberDescriptionPublished
20110111362SURGICAL GUIDES - A drill guide uses a hole in a layer to guide a drill along an axial trajectory while permitting off-axis excursions of the drill during use. A number of such drill guides at varying heights from a target surface may be used sequentially or concurrently to enforce the axial trajectory in three dimensions during a surgical operation. A drill guide may include a hole in a layer that establishes a single point along the axial trajectory, or the drill guide may include multiple layers in a single device to establish two or more points along the trajectory while allowing off-axis insertion of a drill into the guide. The drill guide may be cuttable to accommodate intraoperative changes to the axial trajectory. In embodiments, a window or the like may be provided to permit a surgeon to view drill depth, drill orientation, the surgical site and the like during a procedure.05-12-2011
20110111363METHOD FOR REALIZING AN AXIAL TRAJECTORY IN A SURGICAL DRILLING PROCESS - A drill guide uses a hole in a layer to guide a drill along an axial trajectory while permitting off-axis excursions of the drill during use. A number of such drill guides at varying heights from a target surface may be used sequentially or concurrently to enforce the axial trajectory in three dimensions during a surgical operation. A drill guide may include a hole in a layer that establishes a single point along the axial trajectory, or the drill guide may include multiple layers in a single device to establish two or more points along the trajectory while allowing off-axis insertion of a drill into the guide. The drill guide may be cuttable to accommodate intraoperative changes to the axial trajectory. In embodiments, a window or the like may be provided to permit a surgeon to view drill depth, drill orientation, the surgical site and the like during a procedure.05-12-2011
20110111364COMPUTER-AIDED DESIGN OF A DRILL GUIDE WITH A WINDOW - A drill guide uses a hole in a layer to guide a drill along an axial trajectory while permitting off-axis excursions of the drill during use. A number of such drill guides at varying heights from a target surface may be used sequentially or concurrently to enforce the axial trajectory in three dimensions during a surgical operation. A drill guide may include a hole in a layer that establishes a single point along the axial trajectory, or the drill guide may include multiple layers in a single device to establish two or more points along the trajectory while allowing off-axis insertion of a drill into the guide. The drill guide may be cuttable to accommodate intraoperative changes to the axial trajectory. In embodiments, a window or the like may be provided to permit a surgeon to view drill depth, drill orientation, the surgical site and the like during a procedure.05-12-2011
20110111371COMPUTER-AIDED DESIGN OF A THIN-LAYER DRILL GUIDE - A drill guide uses a hole in a layer to guide a drill along an axial trajectory while permitting off-axis excursions of the drill during use. A number of such drill guides at varying heights from a target surface may be used sequentially or concurrently to enforce the axial trajectory in three dimensions during a surgical operation. A drill guide may include a hole in a layer that establishes a single point along the axial trajectory, or the drill guide may include multiple layers in a single device to establish two or more points along the trajectory while allowing off-axis insertion of a drill into the guide. The drill guide may be cuttable to accommodate intraoperative changes to the axial trajectory. In embodiments, a window or the like may be provided to permit a surgeon to view drill depth, drill orientation, the surgical site and the like during a procedure.05-12-2011
20110112544SURGICAL GUIDE WITH TAPERED HOLES - A drill guide uses a hole in a layer to guide a drill along an axial trajectory while permitting off-axis excursions of the drill during use. A number of such drill guides at varying heights from a target surface may be used sequentially or concurrently to enforce the axial trajectory in three dimensions during a surgical operation. A drill guide may include a hole in a layer that establishes a single point along the axial trajectory, or the drill guide may include multiple layers in a single device to establish two or more points along the trajectory while allowing off-axis insertion of a drill into the guide. The drill guide may be cuttable to accommodate intraoperative changes to the axial trajectory. In embodiments, a window or the like may be provided to permit a surgeon to view drill depth, drill orientation, the surgical site and the like during a procedure.05-12-2011

Joseph Andrew Haber, Newton, MA US

Patent application numberDescriptionPublished
20120102785MAGNETICALLY-SUPPORTED ARTICLE OF FOOTWEAR - A magnetically-supported article of footwear that primarily supports a wearer's weight by repulsive magnetic forces from magnets arranged in and around the article's sole. The magnets are arranged between and around the article's insole and outsole and may be attached to pairs of magnetically-conductive plates located down the length of the article's sole. Each plate has two magnets, one with a north pole facing upwards and one with a north pole facing downward. Also disclosed is an independent magnetically-supported sole assembly suitable for attachment to an existing article of footwear's sole so that, when attached, the weight of the wearer of that article is primarily supported by repulsive magnetic forces.05-03-2012

Kenneth S. Haber, Frederick, MD US

Patent application numberDescriptionPublished
20090086200Spectrometric characterization of pharmaceutical heterogeneity - In one general aspect, a spectroscopic method for monitoring heterogeneity of a sample is disclosed. In this method, sampled spectroscopic measurements are acquired over a range of different micro locations in a macro-sample of the sample. This step is repeated for micro-locations in further macro-samples of the sample, and a statistical measure of chemical heterogeneity is derived from the acquisitions. In another general aspect, differently sized samples are acquired, and a statistical measure of chemical heterogeneity is derived from these acquisitions.04-02-2009
20100007877Narrow-band spectrometric Measurements - Spectrometers and spectrometric measurement methods are disclosed. These employ narrow-band sources positioned in a circular array to perform spectrometric measurements that can employ Hadamard sequences.01-14-2010
20100097599Spectrometric process monitoring - Spectrometric apparatus that include an array of detector elements and exhibits a number of capabilities is disclosed. The elements can be responsive to incident radiation to produce an output signal that includes information from the incident radiation. A spectrally selective element can be located in an optical path between the radiation source and the array, with an analysis module responsive to the output signal operative to analyze spatial distribution of spectral information received by the array. The apparatus can also correct for differences in intensity and spectral variability for spectral image signals and/or compare the spectral image signals with a pattern in spatial-spectral coordinate space. Detector elements can be responsive to scattering, and spatial information in their output can be analyzed.04-22-2010

Patent applications by Kenneth S. Haber, Frederick, MD US

Kenneth S. Haber US

Patent application numberDescriptionPublished
20110238327SPECTROMETRIC CHARACTERIZATION OF HETEROGENEITY - In one general aspect, a spectroscopic method is disclosed. This method includes acquiring a plurality of separate spectral measurements at different locations on a sample and evaluating results of the measurements based on one or more predetermined test criteria. Information from measurements made at the different locations is categorized based on results of the step of evaluating, and results are reported that include information from both the step of acquiring and the step of categorizing.09-29-2011

Kristin Haber US

Patent application numberDescriptionPublished
20100145795Directing internet shopping traffic and tracking revenues generated as a result thereof - A system having a client, a host server, a sponsor server, and a video server, which are all interconnected via the Internet and which operate seamlessly together in order to provide video content to an end user at the client and allow the end user at the client to purchase products and/or services from the sponsor that are featured in the video content provided by the video server. As the user views video content on his or her computer, images associated with segments of the content are periodically provided in conjunction with the video content. Each image contains an image map, which defines areas in the image. Each defined area is associated with a product which is displayed in that area of the image. Each defined area is also associated with an anchored hyperlink which links to web content from a sponsor server. The web content includes product information for that particular product featured in that area of the image. Accordingly, by selecting an item in the image, product information is retrieved from a sponsor server and provided to the user so he or she may purchase the product seen in the video content.06-10-2010

Ludwig Christian Haber, Rutland, MA US

Patent application numberDescriptionPublished
20100189924APPARATUS AND METHOD FOR DIAMOND FILM GROWTH - An apparatus and methods for forming a diamond film, are provided. An example of an apparatus for forming a diamond film includes an electrodeless microwave plasma reactor having a microwave plasma chamber configured to contain a substrate and to contain a reactant gas excited by microwaves to generate a microwave plasma discharge. Gas injection ports extend through an outer wall of the plasma chamber at a location upstream of the plasma discharge and above the substrate. Gas jet injection nozzles interface with the gas injection ports and are configured to form a directed gas stream of reactant gas having sufficient kinetic energy to disturb a boundary layer above an operational surface of the substrate to establish a convective transfer of the film material to the operational surface of the substrate.07-29-2010

Mark Haber, Atlanta, GA US

Patent application numberDescriptionPublished
20100019040PORTABLE SCANNER DEVICE WITH INTEGRAL AUDIO OUTPUT - A portable scanner device with integral audio output for audibly identifying a multiplicity of scanned items for a user is disclosed. The portable scanner device comprises a hand-held housing, a sensor disposed within the housing (the sensor configured to detect and sense a scanned item), an audio output to aurally present audio data to the user of the portable scanner device, a processor to identify the scanned item and to generate an audio response through the audio output, a memory configured to store a plurality of data items for the processor, and a power source disposed within the housing. A speaker, an earphone, a headset and/or a wireless ear piece are used to present the audio data to the user of the portable scanner device.01-28-2010

Marlene Haber, Atlanta, GA US

Patent application numberDescriptionPublished
20100019040PORTABLE SCANNER DEVICE WITH INTEGRAL AUDIO OUTPUT - A portable scanner device with integral audio output for audibly identifying a multiplicity of scanned items for a user is disclosed. The portable scanner device comprises a hand-held housing, a sensor disposed within the housing (the sensor configured to detect and sense a scanned item), an audio output to aurally present audio data to the user of the portable scanner device, a processor to identify the scanned item and to generate an audio response through the audio output, a memory configured to store a plurality of data items for the processor, and a power source disposed within the housing. A speaker, an earphone, a headset and/or a wireless ear piece are used to present the audio data to the user of the portable scanner device.01-28-2010

Raymond G. Haber, Ambler, PA US

Patent application numberDescriptionPublished
20090260557ENSURING INSTALLATION OF DRAIN PLUG WHEN LAUNCHING AQUATIC VESSEL - An auxiliary strap, connected to a tie-down strap for securing a boat to a trailer, is removably anchored to a drain opening in the boat, by being connected to a tethered drain plug, or by being connected to a spring clip that extends into the drain opening. The connection of the tie-down strap to the drain opening reminds the boater to reinstall the drain plug before launching the boat.10-22-2009

Robin Haber, Highland Park, IL US

Patent application numberDescriptionPublished
20110274801Elastomeric multi-function squeezer/strainer device - The present invention is directed to elastomeric perforated sheets that can be used as a squeezer, strainer, juicer, sieve, or sachet. The squeezer/strainer device of the present invention comprises two flexible silicone sheets joined by a connector. The peripheral region of one sheet is adapted to engage a portion of the second sheet, which allows the two sheets to be sealed together around food items such as herbs and spices.11-10-2011
20110274807Elastomeric multi-function squeezer/strainer device - The present invention is directed to an elastomeric perforated sheet that can be used as a squeezer, strainer, juicer, sieve, or sachet. The squeezer/strainer device of the present invention comprises a flexible silicone sheet material with a liquid-impermeable border region framing a perforated central region. The perforated central region contains a plurality of perforations having a size of about 0.5 millimeters to about 1.5 millimeters.11-10-2011

Todd C. Haber, Alpharetta, GA US

Patent application numberDescriptionPublished
20080296480Method and Apparatus for Multiple Scan Rate Swept Wavelength Laser-Based Optical Sensor Interrogation System with Optical Path Length Measurement Capability - The invention relates to optical sensor measurement methods that use a swept wavelength optical source to determine wavelength shift as well as to optical sensor systems that embody and employ these methods. A variable scan rate swept optical source is used to determine the optical path length from the optical interrogator to the optical sensors being measured. This data can then be used as desired or needed in implementing the sensor or making sensor measurements. In particular the data can be used in the optical sensor system to compensate for potential measurement errors due to the finite speed of light in the optical medium interconnecting optical sensors under test.12-04-2008