| Patent application number | Description | Published |
|---|
| 20080221174 | CONTROLLED RELEASE NISOLDIPINE COMPOSITIONS - Controlled release oral dosage formulations containing calcium channel blockers, and methods of use thereof, are provided for the once-a-day treatment of cardiovascular disorders, such as hypertension, angina, and cardiac arrhythmia. The active agent is preferably a dihydropyridine calcium channel blocker, such as nisoldipine. The formulation provides an increase in the bioavailability of the calcium channel blocker as compared to the bioavailability of the calcium channel blocker in other drug delivery formulations known in the art. In one embodiment, the formulation provides an increase in the bioavailability of the calcium channel blocker, nisoldipine, as compared to the same dose of nisoldipine in the coat-core version of the drug (SULAR®). The formulation can be in the form of a trilayer tablet containing a core or central layer and one or more barrier layers. | 09-11-2008 |
| 20100003320 | HYDROPHILIC/LIPOPHILIC POLYMERIC MATRIX DOSAGE FORMULATION - An oral dosage form comprising a pharmaceutical tablet of one or more layers, one of which carries a biologically active substance; the formulation of said tablet includes different percentages of hydrophilic and lipophilic polymeric materials, and adjuvant substances. The tablets of the present invention show a release rate which is independent from the amounts of active substance present in the tablet. | 01-07-2010 |
| 20100196475 | CONTROLLED RELEASE TABLET FORMULATION CONTAINING MAGNESIUM ALUMINOMETASILICATE - The present invention relates to a controlled pharmaceutical dosage forms for oral administration, and in particular to the excipients used to prepare such medicaments. For example, a dosage form for oral administration is provided consisting of a minimum of 15% w/w of magnesium aluminometasilicate, one or more pharmaceutically active agents and optionally one or more pharmaceutically acceptable diluents. | 08-05-2010 |
| 20100291209 | ORGANIC COMPOUNDS - A dosage form adapted for twice-a-day administration comprising a naproxen species in an immediate release phase and an opioid analgesic in a sustained release phase. The dosage form is useful in the treatment of pain. | 11-18-2010 |
| 20110014352 | METHOD AND APPARATUS FOR PRODUCING A CENTRED COMPRESSION COATED TABLET - The present invention provides a method and apparatus for positioning the core of the compression coated tablet in manufacturing techniques for the production of such tablets. | 01-20-2011 |
