| Patent application number | Description | Published |
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| 20090136966 | Normalization of Complex Analyte Mixtures - The present invention relates to methods and compositions for the normalization of complex analyte mixtures. The invention allows the preparation of profiled samples from highly complex analyte mixtures, allowing the identification of relevant targets or biomarkers. The invention also relates to methods for producing devices, such as a support, suitable for normalization of complex analyte samples. The invention can be used for the normalization of any complex mixture, such as immunogenic libraries, particularly of human source, and to identify or produce biomarkers highly relevant to human traits or conditions. | 05-28-2009 |
| 20100227410 | MULTI-IMMUNOAFFINITY BASED ANTIGEN IDENTIFICATION - The present invention relates to methods for identifying antigens from complex analyte samples. More specifically, the invention relates to methods for identifying antigens recognized by monoclonal antibodies in a complex analyte sample. The methods of this invention use a first affinity chromatography via a “multiaffinity” step and a second, “singleaffinity” step that implements parallel affinity chromatography. | 09-09-2010 |
| 20110077164 | EXPRESSION PROFILING PLATFORM TECHNOLOGY - The present invention relates to an efficient mAb panel-based expression profiling technology platform suitable for global and accurate measurement of proteins, peptides and metabolites in complex mixtures. The platform is comprised of new and well established technologies that are coupled in a unique fashion to provide a novel platform technology for (i) the discovery of differentially displayed elements of complex protein, peptide and metabolite mixtures and (ii) the development of robust mAb based assays that detect the differentially expressed elements. | 03-31-2011 |
| Patent application number | Description | Published |
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| 20080310327 | Registry of modular services and a method for automatically selecting an appropriate service to provide particular logical guarantees - A system, method, and computer program product are provided for selecting a service to provide a service operation. | 12-18-2008 |
| 20100014675 | Appraising Systems With Zero Knowledge Proofs - A system, method, and computer program product are provided for requesting a proof of a security policy in a client system. Additionally, a system, method, and computer program product are provided for proving a security policy to an interrogator system. | 01-21-2010 |
| 20100031047 | ATTESTATION ARCHITECTURE AND SYSTEM - An architecture and system are provided for flexible, composable attestation systems. Systems built according to this attestation architecture can be composed to accomplish complex attestation scenarios. The system is designed around composable components to permit flexible recombination. A system, method, and computer program product are provided for proving attestations to an appraiser regarding a target system. In an embodiment, an attestation request is sent from an appraiser to a target system, wherein the attestation request includes queries regarding properties of the target system needed by the appraiser to make trust decisions regarding the target system. The attestation request is forwarded from the target system to an attester which collects the requested data. The attester sends an attestation response to the appraiser, wherein the response includes at least information regarding properties of the target system requested by the appraiser in order to make a trust decision regarding the target system. | 02-04-2010 |
| Patent application number | Description | Published |
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| 20080201195 | SYSTEM AND METOD FOR TRANSFORMING AN ENTERPRISE USING A COMPONENT BUSINESS MODEL - A system and method are described for using a Component Business Model (CBM) to transform a business. A CBM map is used to identify components that collaborate to provide a specified capability, and a repository supporting the CBM map is filtered to provide a view of the identified components that highlights how they collaborate. The view is used to identify component features contributing to the specified capability. The specified capability is then enhanced by a transformation strategy that includes re-engineering particular components, identifying a pattern characterizing the collaboration between components and adding a component to perform the collaborative pattern, and/or adding an additional feature to the collaboration and adding component to perform the additional feature. The CBM repository provides exemplar best practices that can be adapted for use in a re-engineered component. | 08-21-2008 |
| 20080215398 | SYSTEM AND METHOD FOR USING A COMPONENT BUSINESS MODEL TO MANAGE AN ENTERPRISE - A method and system are described for using the structure and relationships between components in a component business model of an enterprise to assign components providing monitoring data to a management component. In response to the monitoring data, the management component executes a business rule invoking a service that alters a behavior of the enterprise. The management component contains data rules limiting the information provided by the assigned components, analysis rules defining the interaction between components, and report rules for consolidating recommendations for altering behavior of the enterprise, including decisions to invest in certain aspects of the business, to reengineer certain processes of the business, and to alter operation of certain aspects of the business. | 09-04-2008 |
| 20080221940 | SYSTEM AND METHOD FOR USING THE COMPONENT BUSINESS MODEL TO ANALYZE BUSINESS VALUE DRIVERS - The method and system uses the component business model as a framework for locating business activities. Business value drivers are identified, related in an influence model, and structured into a prioritized driver tree. The driver tree is used to determine the relative contributions of leaf drivers to the overall value of the business. Business activities contributing to the leaf drivers are then identified, and the relative contributions of the leaf drivers are allocated to the business activities and then rolled up to the components for display as a heat map overlay on a component map. | 09-11-2008 |
| 20090018879 | METHOD AND SYSTEM SUPPORTING BUSINESS SOLUTION VALIDATION IN A COMPONENT BUSINESS MODEL - A method and system for validating business solutions by evaluating the business services from which the solution is composed, aggregating these evaluations in accordance with a service composition structure, and comparing the aggregated evaluation to target objectives for the business solution, where the service evaluations and the target objectives use the same metrics, which are surrogates for the business solution objectives. A business solution has a Business Level Agreement (BLA) which states business objectives. A business service has a Business Service Level Agreement (BSLA) which states operational objectives. A business solution is seen as a composition of business services. Therefore, the BLA is validated by evaluating and then aggregating the BSLA's for all business services from which the business solution is composed, and then comparing the aggregation against target values of the surrogates. Validation occurs: (1) during solution template composition, (2) at service binding times, and (3) during solution execution via business monitoring. | 01-15-2009 |
