Patent application number | Description | Published |
20130116256 | HEXENONE COMPOUNDS AND MEDICAL USE THEREOF - The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof; to a composition comprising a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluent; and also to use of a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof for combating apoptosis, or preventing or treating a disease or disorder associated with apoptosis; and especially use for protecting cardiomyocyte, or preventing or treating a disease or disorder associated with cardiomyocyte apoptosis. | 05-09-2013 |
20130123300 | UREA COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS - A compound of Formula I, or an isomer, pharmaceutically acceptable salt or solvate thereof, is provided. Also, a composition containing a compound of Formula I, or an isomer, pharmaceutically acceptable salt or solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents, is provided. Further, use of a compound of Formula I, or an isomer, pharmaceutically acceptable salt or solvate thereof for anti-apoptosis is provided, preventing or treating a disease or disorder associated with apoptosis; especially for protecting cardiomyocyte, preventing or treating a disease or disorder associated with cardiomyocyte apoptosis. | 05-16-2013 |
20130143917 | (2E)-3-PHENYL-N-[2,2,2-TRIFLUORO-1-[[8-QUINOLINEAMINO)THIOMETHYL]AMINO]ETH- YL]-2-ACRYLAMIDE AND PHARMACEUTICAL USES THEREOF - The present invention relates to an acrylamide compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof, to a composition comprising the compound or an isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluent, and to a use of the compound or the composition for prophylaxis and/or treatment of a disease or disorder associated with cardiomyocyte apoptosis | 06-06-2013 |
20130158022 | Acrylamide Compounds And Use Thereof For Inhibiting Apoptosis - The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate of the compound, and to a composition comprising the compound of Formula I, or the isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents. The present invention also relates to use of the compound of Formula I, or the isomer, pharmaceutically acceptable salt and solvate thereof for combating apoptosis, preventing or treating a disease or disorder associated with apoptosis; and especially use for protecting cardiomyocyte, and for preventing or treating a disease or disorder associated with cardiomyocyte apoptosis. | 06-20-2013 |
20160038445 | ACRYLAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING APOPTOSIS - The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate of the compound, and to a composition comprising the compound of Formula I, or the isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents. The present invention also relates to use of the compound of Formula I, or the isomer, pharmaceutically acceptable salt and solvate thereof for combating apoptosis, preventing or treating a disease or disorder associated with apoptosis; and especially use for protecting cardiomyocyte, and for preventing or treating a disease or disorder associated with cardiomyocyte apoptosis. | 02-11-2016 |
Patent application number | Description | Published |
20100010989 | Method for Efficiently Supporting Interactive, Fuzzy Search on Structured Data - A method to support efficient, interactive, and fuzzy search on text data includes an interactive, fuzzy search on structured data used in applications such as query relaxation, autocomplete, and spell checking, where inconsistencies and errors exist in user queries as well as data. It utilizes techniques to efficiently and interactively answer fuzzy queries on structured data to allow users to efficiently search for information interactively, and they can find records and documents even if these records and documents are slightly different from the user keywords. | 01-14-2010 |
20120059821 | Method for Efficiently Supporting Interactive, Fuzzy Search on Structured Data - A method to support efficient, interactive, and fuzzy search on text data includes an interactive, fuzzy search on structured data used in applications such as query relaxation, autocomplete, and spell checking, where inconsistencies and errors exist in user queries as well as data. It utilizes techniques to efficiently and interactively answer fuzzy queries on structured data to allow users to efficiently search for information interactively, and they can find records and documents even if these records and documents are slightly different from the user keywords. | 03-08-2012 |
Patent application number | Description | Published |
20150219853 | INTEGRATED MULTISTAGE TAPER COUPLER FOR WAVEGUIDE TO FIBER COUPLING - A waveguide coupler has a compression region and an expansion region for coupling light between a silicon waveguide and an optical fiber. The compression region receives light from the silicon waveguide and compresses an optical mode of the light. Light is transmitted from the compression region to an expansion region. The expansion region expands the light to have a larger cross section. Light is then transmitted to the optical fiber. | 08-06-2015 |
20150253472 | HIGH-ORDER-MODE FILTER FOR SEMICONDUCTOR WAVEGUIDES - A high-order-mode (HOM) filter for thick silicon waveguides has a shoulder slab, a waveguide ridge, a first filter ridge, and a second filter ridge. The first filter ridge and the second filter ridge help attenuate higher-order modes from the waveguide ridge while the waveguide ridge guides a fundamental mode. | 09-10-2015 |
20150253501 | DIRECTIONAL SEMICONDUCTOR WAVEGUIDE COUPLER - An optical, directional coupler has a first input, a second input, a first output, and a second output. The coupler is made with a shoulder disposed on a substrate and a first ridge and a second ridge disposed on the shoulder. The first ridge extends from the first input to the first output. The second ridge extends from the second input to the second output. The shoulder, the first ridge, and the second ridge taper to provide coupling and are modified to select a coupling ratio. | 09-10-2015 |
20150255952 | TUNABLE LASER WITH DIRECTIONAL COUPLER - A tunable laser has a first mirror, a second mirror, a gain medium, and a directional coupler. The first mirror and the second mirror form an optical resonator. The gain medium and the directional coupler are, at least partially, in an optical path of the optical resonator. The first mirror and the second mirror comprise binary super gratings. Both the first mirror and the second mirror have high reflectivity. The directional coupler provides an output coupler for the tunable laser. | 09-10-2015 |
20150346429 | WAVEGUIDE MODE EXPANDER USING AMORPHOUS SILICON - A waveguide mode expander couples a smaller optical mode in a semiconductor waveguide to a larger optical mode in an optical fiber. The waveguide mode expander comprises a shoulder made of crystalline silicon and a ridge made of non-crystalline silicon (e.g., amorphous silicon). In some embodiments, the ridge of the waveguide mode expander has a plurality of stages, the plurality of stages have different widths and/or thicknesses at a given cross section. | 12-03-2015 |
20150346430 | WAVEGUIDE MODE EXPANDER HAVING AN AMORPHOUS-SILICON SHOULDER - A waveguide mode expander couples a smaller optical mode in a semiconductor waveguide to a larger optical mode in an optical fiber. The waveguide mode expander comprises a shoulder and a ridge. In some embodiments, the ridge of the waveguide mode expander has a plurality of stages, the plurality of stages having different widths at a given cross section. | 12-03-2015 |
Patent application number | Description | Published |
20130284119 | CIRCULATING FLUIDIZED BED BOILER - A circulating fluidized bed boiler is disclosed. The circulating fluidized bed boiler comprising: a furnace defined and enclosed by water walls, a ceiling and an air distributor, the water walls comprising front and rear walls and left and right side walls (AJ, TK) formed by water cooling tubes, and the water walls are provided with secondary air ports (Y) in the lower part thereof, and furnace flue gas outlets (AB, EF, IJ, KL, OP, ST) being provided in an upper part of the furnace; at least two cyclones connected with the furnace flue gas outlets (AB, EF, IJ, KL, OP, ST); a loop-seal is connected with solid outlets of the cyclones and the lower part of the furnace, respectively; and a flue gas duct connected with flue gas outlets of the cyclones wherein the water cooling wall tubes of the water wall form at least one vertical columnar recessed segment (BCDE, FGHI, SRQP, ONML) recessed toward the inside of the furnace, and the at least one columnar recessed segment (BCDE, FGHI, SRQP, ONML) extends at least 15% of the furnace height in a vertical direction. | 10-31-2013 |
20140299027 | LARGE-SCALE CIRCULATING FLUIDIZED BED BOILER - A large-size circulating fluidized bed boiler, comprising: a furnace having a vertical furnace center line; and at least two groups of cyclones, each cyclone of each group of cyclones having an inlet gas pass communicated with the furnace. A furnace cross section formed by outer sidewalls and located at the inlet gas pass of the cyclone is a polygon having 2×n sides, and n is a positive integer greater than 1. The polygon is axially symmetric with respect to a perpendicular bisector of each side of the polygon, and when n is 2, the polygon is a square. Triangles formed by two endpoints of an inlet of the inlet gas pass of each cyclone at the cross section and an intersection of the furnace center line and the cross section are congruent. A single flow field in communication with each of the inlet is formed in the cross section. | 10-09-2014 |
20150184847 | Large-size Circulating Fluidized Bed Boiler, Air Distributor and Air Distributor Assembly - The present invention provides a circulating fluidized bed boiler, comprising: furnace side walls; a ceiling; an air distribution plate provided at a bottom of a furnace; and at least one air distribution cone provided on the air distribution plate, wherein each air distribution cone extends upwards from the air distribution plate into an interior of the furnace and has a shape gradually tapered in an extending direction, cone side walls which form the air distribution cone are provided with secondary air ports, the cone side walls are separated from the furnace side walls, and a furnace combustion space is formed and surrounded by the ceiling, the furnace side walls, the air distribution plate, and the cone side walls. The present invention further relates to an air distributor for a circulating fluidized bed boiler, the air distributor being provided on an air distribution plate of the boiler, wherein the air distributor is in a form of an air distribution cone, which extends upwards from the air distribution plate into an interior of a furnace to form a shape gradually tapered in an extending direction, and secondary air ports are formed in air distribution cone side walls forming the air distribution cone. The present invention also relates to an air distributor assembly for a circulating fluidized bed boiler. | 07-02-2015 |
Patent application number | Description | Published |
20120195186 | METHOD AND SYSTEM FOR PREVENTING TRAFFIC LOSS CAUSED BY WAIT-TO-RESTORE MECHANISMS IN SERVICE PROTECTION NETWORKS - A method for preventing traffic loss includes transmitting user traffic over an automatic protection switching (“APS”) connection with revertive operation between a first switch and a second switch, determining that the working path on the APS connection has failed, moving user traffic to the protect path of the APS connection, and initiating a wait-to-restore mode including a wait-to-restore time period associated with the first switch. The method also includes, upon termination of the wait-to-restore time period of the first switch, maintaining traffic on the protect path until a message designating the working path is received on the protect path. The method further includes, upon receiving a message designating the working path, switching user traffic to the working path. The APS connection includes the protect path and the working path. | 08-02-2012 |
20120195190 | METHOD AND SYSTEM FOR SOLVING COMMUNICATION FAILURE AND TRAFFIC LOSS IN SERVICE PROTECTION NETWORKS - A method for solving communication failure includes transmitting user traffic over an automatic protection switching (“APS”) connection between a near network node and a far network node, determining that a protect path on the APS connection has failed, sending a message to the far network node that the protect path has failed, and switching user traffic to the working path at the near network node. | 08-02-2012 |
20120315030 | METHOD AND SYSTEM FOR REDUCING TRAFFIC DISTURBANCE IN A COMMUNICATION NETWORK CAUSED BY INTERMITTENT FAILURE - A method may include: (i) in response to clearing of a fault on a working path of a protection switching group to which a first network element is interfaced: (a) transitioning, by the first network element, its state to a first state in which a protection path of the protection switching group is active; and (b) initiating, by the first network element, a wait to restore timer, the wait to restore timer having a duration such that upon expiration of the timer, the first network element is configured to switch the working path to active; and (ii) in response to receiving a message from a second network element interfaced to the protection switching group indicating that a failure has occurred on the working path: (a) maintaining, by the first network element, its state in the first state; and (b) continuing, by the first network element, the wait to restore timer. | 12-13-2012 |
20130003528 | JOINT NEAR-END AND FAR-END STATE MACHINE FOR SERVICE PROTECTION NETWORKS - In one embodiment, a method for telecommunications includes determining the operational state of a first network switch, determining the operational state of a second network switch, determining the existence of an actionable condition, accessing information on the first switch, and changing the operational state of the first switch. The second network switch is coupled to the first network switch by a protected path. Determining the actionable condition and changing the operational state use references to the operational state of the first network switch, the operational state of the second network switch, and the actionable condition. | 01-03-2013 |
20130250961 | VIRTUAL SUBPORT DATA TRAFFIC MANAGEMENT - A network element includes an ingress interface, a VSP queue, and a switch fabric (SWF). The ingress interface includes a first virtual subport (VSP) and a second VSP. The first VSP is configured to receive data traffic. The VSP queue is coupled to the second VSP such that data traffic transmitted to the VSP queue is transmitted from the network element via the second VSP. The SWF is configured to receive data traffic from the first VSP, determine whether an intended recipient of the data traffic is associated with the second VSP, and hairpin the data traffic to the VSP queue when the SWF determines that the intended recipient is associated with the second VSP. | 09-26-2013 |
Patent application number | Description | Published |
20090269751 | DOT1 HISTONE METHYLTRANSFERASES AS A TARGET FOR IDENTIFYING THERAPEUTIC AGENTS FOR LEUKEMIA - The present invention provides polypeptides with histone H3 lysine 79 methyltransferase activity as well as nucleic acids encoding the same. Also provided are methods of using the polypeptides and nucleic acids of the invention in screening assays to identify compounds of interest. Further provided are diagnostic methods for leukemia and prognostic methods to predict the course of the disease in a subject. | 10-29-2009 |
20100151453 | DOT1 HISTONE METHYLTRANSFERASES AS A TARGET FOR IDENTIFYING THERAPEUTIC AGENTS FOR LEUKEMIA - The present invention provides polypeptides with histone H3 lysine 79 methyltransferase activity as well as nucleic acids encoding the same. Also provided are methods of using the polypeptides and nucleic acids of the invention in screening assays to identify compounds of interest. Further provided are diagnostic methods for leukemia and prognostic methods to predict the course of the disease in a subject. | 06-17-2010 |
20130065814 | INDUCTIVE PRODUCTION OF PLURIPOTENT STEM CELLS USING SYNTHETIC TRANSCRIPTION FACTORS - The present invention relates to use of synthetic factors in reprogramming somatic cells to become induced pluripotent stem cells and other cell lineages. Specifically, the present application relates to fusion proteins containing proteins encoded by cell totipotency-related genes and transcription regulatory domains, their coding sequences, expression vectors, and compositions. The present application also relates to methods for reprogramming somatic cells to become induced pluripotent stem cells and other cell lineages, and cells containing the fusion proteins or the coding sequences. | 03-14-2013 |
20150147758 | DOT1 Histone Methyltransferases as a Target for Identifying Therapeutic Agents for Leukemia - The present invention provides polypeptides with histone H3 lysine 79 methyltransferase activity as well as nucleic acids encoding the same. Also provided are methods of using the polypeptides and nucleic acids of the invention in screening assays to identify compounds of interest. Further provided are diagnostic methods for leukemia and prognostic methods to predict the course of the disease in a subject. | 05-28-2015 |
Patent application number | Description | Published |
20140092729 | Data Transmission in a Packet Transport Network (PTN) - The present disclosure describes data transmission in a packet transport network (PTN). A multiple stack device facilitates data transmission between a first edge device of a first PTN technology and a second edge device of a second PTN technology. After receiving a first packet of the first PTN technology from the first edge device, the multiple stack device identifies a first connection with the first edge device according to information of the first packet and identifies a second connection with the second edge device from the first connection based on a relationship between the first connection and the second connection. The first packet is de-encapsulated and re-encapsulated into a second packet of the second PTN technology according to the second connection. The second packet is then forwarded to the second edge device via the second connection. | 04-03-2014 |
20140301401 | PROVIDING AGGREGATION LINK GROUPS IN LOGICAL NETWORK DEVICE - A control plane of a logical network device creates a service link aggregation group and adds one port from each member network device to the service link aggregation group. The logical network device includes member network devices and each port connects the logical network device to the same neighbor device. When a port of the logical network device receives a message with an unknown source address, the control plane determines if the receiving port is in any service link aggregation group. After determining the receiving port is in the service link aggregation group, the control plane configures a data plane of the logical network device with mappings between the address and the ports in the service link aggregation group. | 10-09-2014 |
20140301404 | EXPANDING MEMBER PORTS OF A LINK AGGREGATION GROUP BETWEEN CLUSTERS - According to an example, in a method and an apparatus for expanding member ports of a link aggregation group between clusters, each apparatus in a cluster receives a port joining link aggregation group message sent by a master control board on a master apparatus in the cluster. In response to an apparatus determining that a newly joined port is a port on the apparatus itself and also is the first member port in the link aggregation group of the cluster, the newly joined port is associated with the link aggregation group. By applying the method and the apparatus for expanding member ports of a link aggregation group between clusters in this manner, according to an example, the number of member links in the link aggregation group between clusters is able to be increased, and the robustness of the network interconnection between clusters is also able to be enhanced. | 10-09-2014 |
20150029855 | TRAFFIC ROUTING - The present disclosure relates to a traffic routing method and a traffic routing device. A member device of a stacking system receives traffic destined for a destination node. If there is at least one valid Equal-cost multi-path (ECMP) associated with an address of the destination node in a forwarding table, the member device routes the received traffic to the destination node through the at least one valid ECMP path. Otherwise, the member device selects at least one other member device of the stacking system for routing the received traffic, updates an ECMP path associated with the address of the destination node in the forwarding table to a stacking link connecting the member device with the selected at least one member device, and transmits the received traffic to the selected at least one member device. | 01-29-2015 |
20150110111 | Forward Packet with Edge Device - When a User Edge Device (UED) receives a unicast packet from a user side, the UED searches in a Media Access Control (MAC) table. When a matching entry in the MAC table is found, the UED forwards the unicast packet locally. When no matching entry in the MAC table is found, the UED transmits the unicast packet to a Network Edge Device (NED). When the UED receives a broadcast packet from the user side, the UED broadcasts the broadcast packet within a same Virtual Local Area Network (VLAN) of a local site and forwards to the NED. | 04-23-2015 |
20150334011 | TRAFFIC INTERCONNECTION BETWEEN VIRTUAL DEVICES - According to an example, a virtual port is configured for a current virtual device (VD) to interconnect the current VD with other VDs. The virtual port may be a layer | 11-19-2015 |
20160028624 | VIRTUAL MACHINE MIGRATION - According to an example, virtual machine (VM) migration may include generating a redundant tunnel between a common edge device (ED) of a plurality of common EDs of a multi-site network (MSN) and a gateway ED of the MSN. A gateway media access control (MAC) address and a static route may be configured for forwarding an Internet protocol (IP) message between the common ED and the gateway ED using the redundant tunnel. | 01-28-2016 |