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Guo-Liang

Guo-Liang Lu, Auckland NZ

Patent application numberDescriptionPublished
20120077811PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY - The invention provides novel prodrug compounds comprising a kinase inhibitor and a reductively-activated fragmenting aromatic nitroheterocycle or aromatic nitrocarbocycle trigger, where the compound carries a positive charge. In preferred embodiments, the compounds are of Formula I:03-29-2012

Guo-Liang Yang, Hsinchu City TW

Patent application numberDescriptionPublished
20100285646Method of fabricating power semiconductor device - Wider and narrower trenches are formed in a substrate. A first gate material layer is deposited but not fully fills the wider trench. The first gate material layer in the wider trench and above the substrate original surface is removed by isotropic or anisotropic etching back. A first dopant layer is formed in the surface layer of the substrate at the original surface and the sidewall and bottom of the wider trench by tilt ion implantation. A second gate material layer is deposited to fully fill the trenches. The gate material layer above the original surface is removed by anisotropic etching back. A second dopant layer is formed in the surface layer of the substrate at the original surface by ion implantation. The dopants are driven-in to form a base in the substrate and a bottom-lightly-doped layer surrounding the bottom of the wider trench and adjacent to the base.11-11-2010
20100289075SEMICONDUCTOR DEVICE HAVING INTEGRATED MOSFET AND SCHOTTKY DIODE AND MANUFACTURING METHOD THEREOF - A semiconductor device having integrated MOSFET and Schottky diode includes a substrate having a MOSFET region and a Schottky diode region defined thereon; a plurality of first trenches formed in the MOSFET region; and a plurality of second trenches formed in the Schottky diode region. The first trenches respectively including a first insulating layer formed over the sidewalls and bottom of the first trench and a first conductive layer filling the first trench serve as a trenched gate of the trench MOSFET. The second trenches respectively include a second insulating layer formed over the sidewalls and bottom of the second trench and a second conductive layer filling the second trench. A depth and a width of the second trenches are larger than that of the first trenches; and a thickness of the second insulating layer is larger than that of the first insulating layer.11-18-2010
20110062513OVERLAPPING TRENCH GATE SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF - An overlapping trench gate semiconductor device includes a semiconductor substrate, a plurality of shallow trenches disposed on the semiconductor substrate, a first conductive layer disposed in the shallow trenches, a plurality of deep trenches respectively disposed in each shallow trench, a second conductive layer disposed in the deep trenches, a source metal layer and a gate metal layer. Each of the deep trenches extends into the semiconductor substrate under each shallow trench. The source metal layer is electrically connected to the second conductive layer, and the gate metal layer is electrically connected to the first conductive layer.03-17-2011
20110084335SEMICONDUCTOR DEVICE WITH DRAIN VOLTAGE PROTECTION AND MANUFACTURING METHOD THEREOF - A power semiconductor device with drain voltage protection includes a semiconductor substrate, at least a trench gate transistor device and at least a trench ESD protection device. An upper surface of the semiconductor substrate has a first trench and a second trench. The trench gate transistor device is disposed in the first trench and the semiconductor substrate. The trench ESD protection device is disposed in the second trench, and includes a first doped region, a second doped region and a third doped region. The first doped region and the third doped region are respectively electrically connected to a drain and a gate of the trench gate transistor device.04-14-2011
20110215374POWER SEMICONDUCTOR DEVICE HAVING ADJUSTABLE OUTPUT CAPACITANCE AND MANUFACTURING METHOD THEREOF - A power semiconductor device having adjustable output capacitance includes a semiconductor substrate having a first device region and a second device region defined thereon, at lest one power transistor device disposed in the first device region, a heavily doped region disposed in the semiconductor substrate of the second device region, a capacitor dielectric layer disposed on the heavily doped region, a source metal layer disposed on a top surface of the semiconductor substrate and electrically connected to the power transistor device, and a drain metal layer disposed on a bottom surface of the semiconductor substrate. The source metal layer in the second device, the capacitor dielectric layer and the heavily doped region form a snubber capacitor.09-08-2011
20110291183POWER SEMICONDUCTOR DEVICE HAVING LOW GATE INPUT RESISTANCE AND MANUFACTURING METHOD THEREOF - A power semiconductor device having low gate input resistance and a manufacturing method thereof are provided. The power semiconductor device includes a substrate, at least a trench transistor, a conductive layer, a metal contact plug, an insulating layer, an interlayer dielectric, a gate metal layer, and a source metal layer. The metal contact plug can serve as a buried gate metal bus line, and the metal contact plug can pass under the source metal layer and keeps the area of the source metal layer complete. Accordingly, the present invention can provide a lower gate input resistance without dividing the source metal layer, so the source metal layer can have a larger and complete area for the following packaging and bonding process.12-01-2011

Guo-Liang Yeh, Shindian TW

Patent application numberDescriptionPublished
20110063235PORTABLE ELECTRONIC DEVICE - An exemplary portable electronic device includes a housing, a sensing unit, a signal converting unit, and a processor. The sensing unit, the signal converting unit, and the processor are electrically connected in series and mounted in the housing. The housing includes an operating section formed at one end of the housing as part of the housing. The sensing unit is mounted in the operating section, and configured for detecting the direction of elastic deformation and relative displacement of the operating section in different directions to generate a corresponding command signal. The signal converting unit is configured for transforming the command signal from the sensing unit. The processor receives the signal from the signal converting unit, and generates a control signal to achieve different operations corresponding to the direction of elastic deformation and the relative displacement of the operating section.03-17-2011

Guo-Liang Yu, Hillsborough, CA US

Patent application numberDescriptionPublished
20110008367ANTI-VEGF ANTIBODY - An antibody is provided. In certain cases, the antibody comprises: a) a heavy chain variable domain that comprises CDR regions that are substantially identical to the heavy chain CDR regions of a selected antibody and b) a light chain variable domain that comprises CDR regions that are substantially identical to the light chain CDR regions of the selected antibody, where the antibody binds a selected target.01-13-2011
20110065112METHOD FOR IDENTIFYING LINEAGE-RELATED ANTIBODIES - In certain embodiments, the method may comprise: a) obtaining the antibody sequences from a population of B cells; b) grouping the antibody sequences to provide a plurality of groups of lineage-related antibodies; c) testing a single antibody from each of the groups in a bioassay and, after the first antibody has been identified, d) testing further antibodies that are in the same group as the first antibody in a second bioassay. In another embodiment, the method may comprise: a) testing a plurality of antibodies obtained from a first portion of an antibody producing organ of an animal; b) obtaining the sequence of a first identified antibody; c) obtaining from a second portion of said antibody producing organ the sequences of further antibodies that are related by lineage to said first antibody; and, c) testing the further antibodies in a second bioassay.03-17-2011