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Gunning
Fatima Gunning, Cork IE
| Patent application number | Description | Published |
|---|---|---|
| 20090074416 | Communication Systems - A transmitter transmits signals on multiple channels, and they are wavelength multiplexed according to Coherent WDM. Quality of the received signals is very much enhanced by the transmitter tuning the relative phases of neighbouring channels according to delay characteristics of the optical path. In one example, the transmitter adds a relative delay of ¼ bit period between each data signal and the beat frequency signal for the odd and even channel groups, to counter the receiver side delays introduced by the AMZI. This corresponds to aligning the transmitter such that the eye crossing corresponds to a minimum of the 80 GHz beat signal. In order to obtain a stable phase relationship between adjacent channels the 80 GHz tone is set to a particular value. Any harmonics or sub-harmonics will similarly vary with phase and therefore can also be used as an error signal for a phase stabilisation circuit. The phase stabilisation circuit in the transmitter therefore can maintain a desired stable optimum phase alignment between neighbouring channels. | 03-19-2009 |
James Gunning, Brunswick East AU
James Stuart Gunning, Brunswick East AU
| Patent application number | Description | Published |
|---|---|---|
| 20100017131 | METHOD FOR EVALUATING MEASURED ELECTROMAGNETIC DATA RELATING TO A SUBSURFACE REGION - A method for evaluating measured electromagnetic (EM) data relating to a subsurface region, comprising the steps of: (a) specifying alternative models of the region in terms of input parameters with uncertainty; (b) receiving the measured EM data and an estimated error; and (c) carrying out a Bayesian inversion on the measured data using each of the alternative models to attribute a probability to each model on the basis of the measured data and estimated error. The method allows physical measurements with error to be translated into fundamental parameters which can be used to assess business risk and uncertainty for making decisions, and also provides for parameters and models which can typically be directly estimated by a geoscientist on a coarse spatial grid to be used as an input, and validated using the measured data with error. | 01-21-2010 |
| 20100017132 | METHOD FOR EVALUATING MEASURED ELECTROMAGNETIC DATA RELATING TO A SUBSURFACE REGION - A method for evaluating measured electromagnetic (EM) data relating to a subsurface region, comprising the steps of: (a) specifying at least one model of the region in terms of fundamental parameters with uncertainty, using a fundamental inversion grid; (b) receiving the measured EM data and an estimated error; (c) translating the fundamental parameters of the model to meta parameters of the region and to a computational grid suitable for forward modelling and comparison to the measured EM data, using relationships with uncertainty; and (d) carrying out a Bayesian inversion using the measured data and estimated error to produce an output comprising fundamental parameters of the region on the fundamental inversion grid with uncertainty. The method allows physical measurements with error to be translated into fundamental parameters which can be used to assess business risk and uncertainty for making decisions, and also provides for parameters and models which can typically be directly estimated by a geoscientist on a coarse spatial grid to be used as an input, and validated using the measured data with error. | 01-21-2010 |
John E. Gunning, Oak Ridge, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20120114102 | X-RAY BACKSCATTER IMAGING OF NUCLEAR MATERIALS - The energy of an X-ray beam and critical depth are selected to detect structural discontinuities in a material having an atomic number Z of 57 or greater. The critical depth is selected by adjusting the geometry of a collimator that blocks backscattered radiation so that backscattered X-ray originating from a depth less than the critical depth is not detected. Structures of Lanthanides and Actinides, including nuclear fuel rod materials, can be inspected for structural discontinuities such as gaps, cracks, and chipping employing the backscattered X-ray. | 05-10-2012 |
Kerry Gunning, Coralville, IA US
| Patent application number | Description | Published |
|---|---|---|
| 20120077191 | GENOTYPING DNA - Described herein are compositions and methods useful for the detection of nucleic acid variations. Ligation within a probe or between probes is used to distinguish between probes perfectly complementary to a target and those containing a mismatch. Nucleotide fill-in/extension steps are optionally applied according to the type of assay performed. A circularization and relinearization step can be applied to create a template for further amplification and detection. In certain aspects, portions of a target sequence or its complement are not amplified. | 03-29-2012 |
Kerry B. Gunning, Coralville, IA US
| Patent application number | Description | Published |
|---|---|---|
| 20090136916 | METHODS AND MICROARRAYS FOR DETECTING ENTERIC VIRUSES - The present invention relates to methods, microarrays and kits for detecting one or more human astrovirus serotypes in a sample (e.g., a fecal sample) from an individual. The method includes amplifying nucleic acid molecules of the sample with one or more primers, to thereby obtain an amplified nucleic acid product; contacting the amplified nucleic acid product with one or more serotype specific probes having a nucleic acid sequence that is specific for only one astrovirus serotype in the group of astroviruses being assessed, wherein the nucleic acid sequence includes between about 9 and 25 nucleic acid bases (e.g., SEQ ID NO: 5-24); and detecting the hybridization complex. The presence of hybridization complexes with a serotype specific probe indicates the presence of one or more specific astrovirus serotypes, and the absence of hybridization complexes with a serotype specific probe indicates the absence of the specific astrovirus serotype. Identification of the astrovirus serotypes allows for one to diagnose an individual infected with the serotype. The present invention further includes microarrays having any one of the astrovirus specific probe, or kits having microarrays and reagents for carrying out the assay. | 05-28-2009 |
| 20090143243 | MICROARRAY SYSTEM WITH IMPROVED SEQUENCE SPECIFICITY - The invention provides a novel array method for nucleic acid sequence detection with improved specificity which allows for detection of genetic variation, from simple SNPs (where the variation occurs at a fixed position and is of limited allelic number) to more complex sequence variation patterns (such as with multigene families or multiple genetic strains of an organism where the sequence variation between the individual members is neither fixed nor consistent). The array is comprised of short, synthetic oligonucleotide probes attached to a solid surface which are hybridized to single-stranded targets. Single stranded targets can be produced using a method that employs primers modified on the 5′ end to prohibit degradation by a 5′-exonuclease that is introduced to degrade the unprotected strand. The invention further provides for printing buffers/solutions for the immobilization of oligonucleotide probes to an array surface. The invention also provides hybridization and wash buffers and conditions to maximize hybridization specificity and signal intensity, and reduce hybridization times. | 06-04-2009 |
| 20120077712 | MICROARRAY SYSTEM WITH IMPROVED SEQUENCE SPECIFICITY - The invention provides a novel array method for nucleic acid sequence detection with improved specificity which allows for detection of genetic variation, from simple SNPs (where the variation occurs at a fixed position and is of limited allelic number) to more complex sequence variation patterns (such as with multigene families or multiple genetic strains of an organism where the sequence variation between the individual members is neither fixed nor consistent). The array is comprised of short, synthetic oligonucleotide probes attached to a solid surface which are hybridized to single-stranded targets. Single stranded targets can be produced using a method that employs primers modified on the 5′ end to prohibit degradation by a 5′-exonuclease that is introduced to degrade the unprotected strand. The invention further provides for printing buffers/solutions for the immobilization of oligonucleotide probes to an array surface. The invention also provides hybridization and wash buffers and conditions to maximize hybridization specificity and signal intensity, and reduce hybridization times. | 03-29-2012 |
Leroy Gunning, Deland, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20090207421 | Laser 3-Point Distance and Angle Calculator - A laser distance and angle calculator that will give three measured distances simultaneously; for example from Point A to B, Point A to C and Point B to C. It will also calculate the angle at each intersecting points. The angle at your point of reference is required, but the other angles are calculated. | 08-20-2009 |
Mark Gunning, Redhill GB
| Patent application number | Description | Published |
|---|---|---|
| 20090141273 | OPTICAL APPARATUS - An optical apparatus includes an optical fibre having a radiation inlet, a radiation outlet and a termination by which optical radiation is transmitted from the fibre, a retroreflector spaced from the termination and aligned with the path of radiation from the termination such that the radiation is reflected back along the same path onto the termination and the reflected radiation passes back along the same fibre to the radiation inlet. | 06-04-2009 |
Mark B. Gunning, Austin, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090133027 | Systems and Methods for Project Management Task Prioritization - A project management task prioritization system is provided to refine the prioritization factors for tasks in a project based on changes to the order of performing the tasks. The initial proposed order for performing the tasks is provided by the system to the person responsible for the task in a graphical format that allows the person to drag and drop the tasks, adjusting the order of the tasks to their preferred order. A neural network comparator is used to compare the task prioritization factors associated with each pair of tasks that are altered in order to determine a relative priority. The neural network system updates the task prioritization factors based on the changes in order the tasks are to be performed. | 05-21-2009 |
Patrick Gunning, Mississauga CA
| Patent application number | Description | Published |
|---|---|---|
| 20120130079 | Compounds That Suppress Cancer Cells and Exhibit Antitumor Activity - The present invention provides compounds S3I-201.1066 (Formula 1) and S3I-201.2096 (Formula 2) as selective Stat3 binding agents that block Stat3 association with cognate receptor pTyr motifs, Stat3 phosphorylation and nuclear translocation, Stat3 transcriptional function, and consequently induced Stat3-specific antitumor cell effects in vitro and antitumor response in vivo. | 05-24-2012 |
Paul Gunning, York GB
| Patent application number | Description | Published |
|---|---|---|
| 20110059312 | BIOACTIVE MATERIAL - The present invention relates to a bioactive material and to a method of producing a bioactive material which is suitable for use as an implant or for use as a bone substitute for repairing bone. | 03-10-2011 |
Phil Gunning, Godmanchester GB
| Patent application number | Description | Published |
|---|---|---|
| 20110190249 | THERAPEUTIC METHODS AND USES OF SAPOGENINS AND THEIR DERIVATIVES - The invention discloses therapeutic methods and uses of certain steroidal sapogenins, related compounds and derivatives thereof, in the treatment of non-cognitive neurodegeneration, non-cognitive neuromuscular degeneration, motor-sensory neurodegeneration or receptor dysfunction or loss in the absence of cognitive, neural and neuromuscular impairment. | 08-04-2011 |
Phil Gunning, Grantchester GB
| Patent application number | Description | Published |
|---|---|---|
| 20080207576 | Substituted sapogenins and their use - The invention discloses substituted sapogenins and their use in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical composition are also disclosed | 08-28-2008 |
| 20100087411 | SUBSTITUTED SAPOGENINS AND THEIR USE - The invention discloses substituted sapogenins and their use in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical composition are also disclosed | 04-08-2010 |
Philip James Gunning, Cambridgeshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100056767 | SELECTIVE SEPARATION OR EXTRACTION OF STEROIDAL GLYCOSIDES BY SUPERCRITICAL FLUID EXTRACTION USING CARBON DIOXIDE - A method for selectively separating desirable steroidal glycosides from undesirable components present in plant material of the Asclepiadaceae family containing the same. The method comprises contacting the plant material or material derived therefrom (herein: “the material”) with liquid or supercritical carbon dioxide under conditions whereby the desirable steroidal glycosides dissolve in the liquid or supercritical carbon dioxide in preference to the undesirable components, and subsequently recovering the desirable steroidal glycosides from the carbon dioxide solution. | 03-04-2010 |
Simon Gunning, Canada Bay AU
| Patent application number | Description | Published |
|---|---|---|
| 20080260789 | Insecticidal polypeptides and methods of use thereof - A family of insecticidal polypeptides expressed in the venom gland of spiders of the genera | 10-23-2008 |
Simon Gunning, Auckland Central NZ
| Patent application number | Description | Published |
|---|---|---|
| 20110237502 | Insecticidal Polypeptides and Methods of Use Thereof - A family of insecticidal polypeptides expressed in the venom gland of spiders of the genera | 09-29-2011 |