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Guiles, US
Joseph Guiles, Lafayette, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080207703 | Antibacterial heterocyclic ureas - The present invention provides novel heterocyclic urea compounds having useful antibacterial activity, pharmaceutical compositions comprising one or more of these compounds, methods of making the same, and methods of using the same. | 08-28-2008 |
| 20080227808 | Substituted Phenylether-Thienopyridone Compounds With Antibacterial Activity - Novel bicyclic heteroaromatic compounds are provided that are inhibitors of bacterial methionyl tRNA synthetase (MetRS). Compounds of the invention generally have a left hand side phenylether constituent and a right hand side thienopyridone constituent. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, particularly as anti- | 09-18-2008 |
| 20090163536 | METHODS AND COMPOUNDS FOR TREATMENT OF CLOSTRIDIUM BASED INFECTION - Methionyl tRNA synthetase inhibitors (MetRS) are provided for use in therapy as antibacterial agents in | 06-25-2009 |
| 20100286169 | Antibacterial Sulfone and Sulfoxide Substituted Heterocyclic Urea Compounds - The present invention provides novel sulfone and sulfoxide substituted heterocyclic urea compounds having useful antibacterial activity. Use of these compounds as pharmaceutical compositions and methods of production are provided. | 11-11-2010 |
Joseph W. Guiles, Lafayette, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20090054667 | Transition metal catalyzed cross-coupling of 1-halo-1-haloalkene compounds - Methods for introducing a 1-halo-1-haloalkene compound onto an aromatic or heteroaromatic ring are provided, including processes for the production of certain 1-halovinyl aryl or heteroaryl derivatives in which the 1-halovinyl group is either 1-fluoro or 1-chlorovinyl and the aromatic species phenyl or thiophene, the processes including coupling an arylmagnesium species with a dihalo olefin in the presence of a nickel or iron catalyst. | 02-26-2009 |
Joseph W. Guiles, Bedminster, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080280784 | APPARATUS AND METHOD FOR USE IN SOLID PHASE CHEMICAL SYNTHESIS - An apparatus is disclosed for use in solid-phase chemical synthesis procedures. The apparatus allows the separation of a cleaved product from the solid-phase used to make the product, and subsequent removal of the solid-phase from the apparatus. The apparatus allows the cleaved product to be concentrated within the apparatus without transfer to another device. | 11-13-2008 |
Marvin A. Guiles, Stow, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090069842 | Surgical instrument - A medical instrument having a proximal control handle and a distal tool that are intercoupled by an elongated instrument shaft that is meant to pass internally of an anatomic body, proximal and distal movable members that respectively intercouple the proximal control handle and the distal tool with the instrument shaft, cable control means disposed between the movable members, an actuation member at the handle for controlling the distal tool through the movable members, and a coupler for selectively engaging or disengaging separable cable segments of the actuation member. | 03-12-2009 |
Melvin Guiles, Grand Haven, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100147728 | ENERGY ABSORBING APPARATUS FOR SHIPPING CONTAINER - An energy-absorbing bulkhead apparatus includes high-strength roll formed tubular bars, and a bar-supporting sheet to distribute stress from product shifting in large shipping containers during transport. Parts are re-useable and can be quickly installed into the shipping container at selected locations such as near the container's doors. The bars can be swept and/or have deformed/configured ends shaped to engage channel features in side walls of the large shipping container. The bars may define spaced tubes and a tie rod for added strength. For example, the bars can be steel having 120 KSI to 220 KSI tensile strength, and have a cross-section 2-3 inches in depth and 4-6 inches in height, a length of 94 long, and a longitudinal sweep of 6 inches curvature. A flexitank can be positioned in the shipping container and supported by a combination of the bulkhead. | 06-17-2010 |