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Guido Cappuccilli, San Mateo US

Guido Cappuccilli, San Mateo, CA US

Patent application numberDescriptionPublished
20090169576INFLUENZA COMBINATORIAL ANTIGEN VACCINE - The invention provides a combinatorial influenza vaccine composition for use in providing prophylactic protection in humans against influenza viruses or animals, and a method of producing the vaccine.07-02-2009
20090176654Universal fibronectin type III binding-domain libraries - Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.07-09-2009
20090215639Method of Producing Human IgG Antibodies with Enhanced Effector Functions - A method for generating human IgG08-27-2009
20090299046SELF-ASSEMBLING OLIGONUCLEOTIDES AND METHODS - A composition comprising individual single-stranded oligonucleotides capable of self assembling to form a pair of complementary, substantially contiguous single strands of a double-stranded nucleic acid filament, and a method for forming such filaments are disclosed.12-03-2009
20100152063UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES - Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.06-17-2010
20110021746UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES - Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having hign binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins.01-27-2011
20110124527UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES - Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.05-26-2011
20110245108Universal Antibody Libraries - Universal antibody libraries are described which are synthetic and derived from expressed human antibody sequences selected accordingly to certain criteria, for example, that the sequences are derived from naturally-occurring antibodies expressed in response to a certain antigen class (e.g., small molecule, polysaccharide, peptide, or protein) and having CDR regions engineered for optimal diversity. Methods for making and screening such libraries for isolating therapeutics suitable for treating disease are also disclosed.10-06-2011

Patent applications by Guido Cappuccilli, San Mateo, CA US