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Guida, US
Anthony D. Guida, Newark, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20080234130 | Compositions providing tolerance to multiple herbicides and methods of use thereof - Methods and compositions are provided related to improved plants that are tolerant to more than one herbicide. Particularly, the invention provides plants that are tolerant of glyphosate and are tolerant to at least one ALS inhibitor, and methods of use thereof. The glyphosate/ALS inhibitor-tolerant plants comprise a polynucleotide that encodes a polypeptide that confers tolerance to glyphosate and a polynucleotide that encodes an ALS inhibitor-tolerant polypeptide. In specific embodiments, a plant of the invention expresses a GAT polypeptide and an HRA polypeptide. Methods to control weeds, improve plant yield, and increase transformation efficiencies are provided. | 09-25-2008 |
Carmine Guida, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110301983 | System and Method for Quoting, Selling, Distributing and Tracking Insurance Products - The system relates to an automated method for selling a variety of insurance products to a single individual user. In one aspect of the system, a first database is used for storing demographic information about the user, a second database is used for mapping property types to available insurance products, and the system reuses demographic information stored and retrieved from the first database to provide insurance quotes for a plurality of insurance products. | 12-08-2011 |
James Paul Guida, Miller Place, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110099694 | Apparatus for Mitigating a Loss of or Damage to Protective Eye Goggles used in Conjunction with a Sporting Helmet - An apparatus for mitigating a loss of or damage to protective eye goggles used in conjunction with a sporting helmet includes two goggle strap clips joinable to the sporting helmet on opposing sides. Each of the goggle strap clips includes a long, flat bottom surface for joining to the sporting helmet. Two upper legs are L-shaped and have an opening between ends of the upper legs for enabling a goggle strap to pass through the goggle strap clip and be secured in place. The ends are curved for enabling easy installation and removal the goggle strap from the goggle strap clip. A seamless construction and smooth edges mitigates snags in the goggle strap as it is installed or removed. Smooth outer faces enables logos to be embossed or printed thereon. A flexible material for enables the flat bottom surface to conform to a curved shape of the sporting helmet. | 05-05-2011 |
Nicholas R. Guida, Sandpoint, ID US
| Patent application number | Description | Published |
|---|---|---|
| 20110127383 | ACTIVE WINGLET - An active winglet includes a body portion substantially parallel to a wing of an aircraft, as if it were an extension of the wing, and an angled portion that projects at an upward angle from the body portion. The body portion is attachable to an aircraft wing and includes a controllable airflow modification device coupled thereto. By virtue of having a controllable airflow modification device, the winglet is capable of adjusting a control surface of the controllable airflow modification device in response to in-flight conditions, to reduce wing loads, increase range, and increase efficiency. | 06-02-2011 |
| 20110186689 | ACTIVE WINGLET - An active winglet includes a body portion substantially parallel to a wing of an aircraft, as if it were an extension of the wing. The body portion is attachable to an aircraft wing and includes a controllable airflow modification device coupled thereto. By virtue of having a controllable airflow modification device, the winglet is capable of adjusting a control surface of the controllable airflow modification device in response to in-flight conditions, to reduce wing loads, increase range, and/or increase efficiency. | 08-04-2011 |
Patrick Michael Guida, West Boylston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100190615 | Energy absorbing suspension equipment for rowing and general exercise machines - An exercise device or exercise device attachment with an energy absorbing component configured to change shape so as to absorb energy in response to a compressive force by the user. Said energy absorption component returns substantially to its first shape in response to the removal of the compressive force. The energy-absorbing apparatus is configured to reduce a reaction force exerted on the user of said exercise equipment. | 07-29-2010 |
Renato Guida, Niskayuna, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120103066 | Gas Detection System - A gas detection system is provided for identifying a gas. The gas detection system includes a sensing module with a hollow chamber enclosed by a chamber housing. Additionally, the sensing module includes an optical sensing fiber positioned within the hollow chamber. The optical sensing fiber includes a gas sensor including a fiber Bragg grating positioned at a grating location along the optical sensing fiber, and a sensing layer affixed to an exterior surface of the optical sensing fiber at the grating location. After the gas is directed into the hollow chamber, the sensing layer and the gas exchange heat energy, based in part on a heat transfer coefficient of the gas. The exchange of the heat energy induces a shift in a Bragg resonant wavelength of the fiber Bragg grating which exceeds a threshold shift required for detection, where the shift is used to identify the gas. | 05-03-2012 |
Renato Guida, Wynantskill, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090257055 | HOLLOW-CORE WAVEGUIDE-BASED RAMAN SYSTEMS AND METHODS - Embodiments of the invention include a system for sensing homonuclear diatomic molecules, such as, for example, nitrogen. Other embodiments include a method for sensing homonuclear diatomic molecules. The system may include a light source, a hollow-core wave-guiding device that exhibits a low attenuation at predetermined operating optical frequencies and is in optical communication with the light source, a gas introduction system for introducing a gaseous medium between the light source and the hollow-core wave-guiding device, and a detector in optical communication with the hollow-core wave-guiding device. | 10-15-2009 |
| 20100195089 | WIND VELOCITY MEASUREMENT SYSTEM AND METHOD - A wind anemometer comprises a light source for transmitting pulsed light signals, a receiver for receiving backscattered signals from airborne particles for each pulse of the transmitted pulsed light signals, a detector for detecting the received backscattered signals, and a processor to determine location of the airborne particles with respect to the anemometer based on the detected backscattered signals. The processor estimates wind velocity using changes in location of the airborne particles over at least one time interval. | 08-05-2010 |
| 20100321838 | ARC FLASH DETECTION SYSTEM - An apparatus to detect arc is presented. The apparatus includes a fiber sensor to detect characteristics of an arc flash and a processor to process at least two characteristics of the arc flash. The processor is further configured to generate an arc fault signal. A protective device is configured to mitigate the arc flash based on the arc fault signal. | 12-23-2010 |
| 20110052115 | SYSTEM AND METHOD FOR TEMPERATURE CONTROL AND COMPENSATION FOR FIBER OPTIC CURRENT SENSING SYSTEMS - A fiber optic sensor system employs at least one light source that operates to generate light having one or more desired wavelengths. A first optical fiber based sensor transparent to a desired light wavelength operates to sense a magnetic field emitted from a predetermined electrical conductor or a current flowing through the electrical conductor. A temperature sensor that may be another optical fiber based sensor operates to sense an operating temperature associated with the first optical fiber based sensor in response to the light generated by the light source. Signal-processing electronics adjust the sensed current to substantially compensate for temperature induced errors associated with the sensed current in response to the measured operational temperature of the fiber optic sensor. | 03-03-2011 |
| 20110075142 | OPTICAL DETECTION SYSTEM - Optical detection systems and optical spectrometric systems are presented. One embodiment is a parallelized optical detection system. The detection system includes collector optics configured to receive an input optical signal, a plurality of optical filters and a plurality of tunable cavities. The collector optics includes at least one collector lens and at least one fiber multiplexer. The plurality of optical filters are configured to receive the input optical signal from the fiber multiplexer, and have serially varying pass band configured to filter the input optical signal at respective bandwidths. Each of the plurality of tunable cavities is optically coupled to each filter of the respective plurality of optical filters to receive a respective filtered output signal. The plurality of tunable cavities have band-pass frequencies with center frequencies staggered. At least one fiber demultiplexer is configured to receive respective filtered signals from the plurality of tunable cavities, and at least one detector is configured to receive and detect an output optical signal from the demultiplexer. | 03-31-2011 |
| 20110211795 | HERMETICALLY SEALED FIBER SENSING CABLE - In one aspect, the present invention provides a hermetically sealed fiber sensing cable comprising: a core fiber comprising at least one Bragg grating region, an outer surface and a length; a fiber cladding in contact with the core fiber along the entire length of the core fiber, the fiber cladding having an outer surface and a length; a carbon layer disposed upon the outer surface of the fiber cladding along the entire length of the fiber cladding, the carbon layer comprising diamond-like carbon; a hydrogen ion absorption layer in contact with the carbon layer, the hydrogen ion absorption layer being disposed on the outer surface of the carbon layer; and an outer sleeve. Also provided in another aspect of the present invention, is a component for a hermetically sealed fiber sensing cable. | 09-01-2011 |
| 20110242546 | System For Monitoring a Relative Displacement of Components - A system is provided for monitoring a relative displacement of a pair of end-winding components. The system includes a structure mounted to the end-winding components. The system further includes a fiber Bragg grating mounted to a non-curved surface of the structure, where the fiber Bragg grating is configured to reflect incident radiation having a peak intensity at a respective wavelength based on a strain of the fiber Bragg grating. The structure is configured so that the strain produced by the structure limits a magnitude of the strain of the fiber Bragg grating within a predetermined range over a span of the relative displacement of the pair of end-winding components. | 10-06-2011 |
| 20120029835 | FIBER OPTIC CARBON DIOXIDE PURITY SENSOR PACKAGE AND SYSTEM - A carbon dioxide (CO2) purity sensor package includes a fiber core, a periodic refractive index modulated fiber grating structure within the fiber core and a fiber cladding. A thermally conductive sensing layer is positioned about a portion of the fiber cladding surrounding the periodic refractive index modulated fiber grating structure. A gas chamber encloses the fiber cladding with the thermally conductive sensing layer. | 02-02-2012 |
Renato Guida, Wynanskill, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100007876 | HOLLOW-CORE WAVEGUIDE-BASED RAMAN SYSTEMS AND METHODS - Embodiments of the invention include a method for sensing. Other embodiments include a method for sensing molecules, for example, homonuclear diatomic molecules. The method may include transmitting light from a light source through a hollow-core wave-guiding device that exhibits a low attenuation at predetermined operating optical frequencies; introducing a gaseous medium between the light source and the hollow-core wave-guiding device; and detecting molecules within the gas. | 01-14-2010 |
Wayne Guida, St. Petersburg, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20110201576 | Small molecule inhibitors of stat3 with anti-tumor activity - The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S3I-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents. | 08-18-2011 |
| 20110201609 | PROTEASOME INHIBITORS FOR SELECTIVELY INDUCING APOPTOSIS IN CANCER CELLS - The subject invention concerns compounds having activity as inhibitors of proteasomes and methods of using the subject compounds. In one embodiment, a compound of the invention has the chemical structure shown in formula I: | 08-18-2011 |
Wayne Guida, Saint Petersburg, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20090069420 | Small molecule inhibitors of STAT3 with anti-tumor activity - The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S3I-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents. | 03-12-2009 |
Wayne C. Guida, Tampa, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20110009354 | 5',-SUBSTITUTED ADENOSYNES PREPARATION THEREOF AND USE AS INHIBITORS OF S-ADENOSYLMETHIONINE DECARBOXYLASE - The crystal structure of the complex of S-adenosylmethionine methyl ester with hΛdoMetDC F223A, a mutant where the stacking of the aromatic rings of F7, adenine and F223 would be eliminated. The structure of this mutant with the ester shows that the ligand still maintains a syn conformation aided by pi-pi interactions to F7, hydrogen bonds to the backbone of Glu67, and electrostatic interactions. Several series of AdoMet substrate analogues with a variety of substituents at the 8 position of adenine were synthesized and analyzed for their ability to inhibit hAdoMetDC. To understand these results, virtual modeling of the enzyme inhibitor complexes and the crystal structures of human AdoMetDC with 5′-deoxy-5′-[N-methyl-N-[2-(aminooxy)ethyl]amino-8-methyl]adenosine (MAOEMA) and 5′-deoxy-5′-[N-methyl-N-[4-(aminooxy)butyl]amino-8-ethyl]adenosine (MAOBEA) at the active site have been determined experimentally. | 01-13-2011 |