Patent application number | Description | Published |
20110127383 | ACTIVE WINGLET - An active winglet includes a body portion substantially parallel to a wing of an aircraft, as if it were an extension of the wing, and an angled portion that projects at an upward angle from the body portion. The body portion is attachable to an aircraft wing and includes a controllable airflow modification device coupled thereto. By virtue of having a controllable airflow modification device, the winglet is capable of adjusting a control surface of the controllable airflow modification device in response to in-flight conditions, to reduce wing loads, increase range, and increase efficiency. | 06-02-2011 |
20110186689 | ACTIVE WINGLET - An active winglet includes a body portion substantially parallel to a wing of an aircraft, as if it were an extension of the wing. The body portion is attachable to an aircraft wing and includes a controllable airflow modification device coupled thereto. By virtue of having a controllable airflow modification device, the winglet is capable of adjusting a control surface of the controllable airflow modification device in response to in-flight conditions, to reduce wing loads, increase range, and/or increase efficiency. | 08-04-2011 |
Patent application number | Description | Published |
20120187251 | Multiple Controllable Airflow Modification Devices - An active wing extension includes a body portion substantially parallel to a wing of an aircraft, as if it were an extension of the wing. The body portion is attachable to an aircraft wing and includes multiple controllable airflow modification devices coupled thereto. By virtue of having multiple controllable airflow modification devices, the wing extension is capable of adjusting control surfaces of the multiple controllable airflow modification devices in response to in-flight conditions, to reduce wing loads, improve wing fatigue characteristics, increase range, and/or increase efficiency. | 07-26-2012 |
20130037659 | Control Quadrant - An aircraft with a control system having joint control for a throttle and a propeller of an aircraft may be modified to decouple the joint control of a throttle and a propeller. Control of the throttle and propeller may be independent of the other. Exemplary modification of a control system may use new structures, existing structures, repurpose existing structures, or use a combination thereof. Additionally or alternatively, modification of a control system may provide controls with tactile distinction to a user. | 02-14-2013 |
20140306067 | CONTROLLABLE AIRFLOW MODIFICATION DEVICE PERIODIC LOAD CONTROL - An active wing extension includes a body portion substantially parallel to a wing of an aircraft, as if it were an extension of the wing. The body portion is attachable to an aircraft wing and includes multiple controllable airflow modification devices coupled thereto. By virtue of having multiple controllable airflow modification devices, the wing extension is capable of adjusting control surfaces of the multiple controllable airflow modification devices in response to in-flight conditions, to reduce wing loads, improve wing fatigue characteristics, increase range, reduce torsional loads, alleviate flutter, and/or increase efficiency. | 10-16-2014 |
Patent application number | Description | Published |
20090257055 | HOLLOW-CORE WAVEGUIDE-BASED RAMAN SYSTEMS AND METHODS - Embodiments of the invention include a system for sensing homonuclear diatomic molecules, such as, for example, nitrogen. Other embodiments include a method for sensing homonuclear diatomic molecules. The system may include a light source, a hollow-core wave-guiding device that exhibits a low attenuation at predetermined operating optical frequencies and is in optical communication with the light source, a gas introduction system for introducing a gaseous medium between the light source and the hollow-core wave-guiding device, and a detector in optical communication with the hollow-core wave-guiding device. | 10-15-2009 |
20100195089 | WIND VELOCITY MEASUREMENT SYSTEM AND METHOD - A wind anemometer comprises a light source for transmitting pulsed light signals, a receiver for receiving backscattered signals from airborne particles for each pulse of the transmitted pulsed light signals, a detector for detecting the received backscattered signals, and a processor to determine location of the airborne particles with respect to the anemometer based on the detected backscattered signals. The processor estimates wind velocity using changes in location of the airborne particles over at least one time interval. | 08-05-2010 |
20100321838 | ARC FLASH DETECTION SYSTEM - An apparatus to detect arc is presented. The apparatus includes a fiber sensor to detect characteristics of an arc flash and a processor to process at least two characteristics of the arc flash. The processor is further configured to generate an arc fault signal. A protective device is configured to mitigate the arc flash based on the arc fault signal. | 12-23-2010 |
20110052115 | SYSTEM AND METHOD FOR TEMPERATURE CONTROL AND COMPENSATION FOR FIBER OPTIC CURRENT SENSING SYSTEMS - A fiber optic sensor system employs at least one light source that operates to generate light having one or more desired wavelengths. A first optical fiber based sensor transparent to a desired light wavelength operates to sense a magnetic field emitted from a predetermined electrical conductor or a current flowing through the electrical conductor. A temperature sensor that may be another optical fiber based sensor operates to sense an operating temperature associated with the first optical fiber based sensor in response to the light generated by the light source. Signal-processing electronics adjust the sensed current to substantially compensate for temperature induced errors associated with the sensed current in response to the measured operational temperature of the fiber optic sensor. | 03-03-2011 |
20110075142 | OPTICAL DETECTION SYSTEM - Optical detection systems and optical spectrometric systems are presented. One embodiment is a parallelized optical detection system. The detection system includes collector optics configured to receive an input optical signal, a plurality of optical filters and a plurality of tunable cavities. The collector optics includes at least one collector lens and at least one fiber multiplexer. The plurality of optical filters are configured to receive the input optical signal from the fiber multiplexer, and have serially varying pass band configured to filter the input optical signal at respective bandwidths. Each of the plurality of tunable cavities is optically coupled to each filter of the respective plurality of optical filters to receive a respective filtered output signal. The plurality of tunable cavities have band-pass frequencies with center frequencies staggered. At least one fiber demultiplexer is configured to receive respective filtered signals from the plurality of tunable cavities, and at least one detector is configured to receive and detect an output optical signal from the demultiplexer. | 03-31-2011 |
20110211795 | HERMETICALLY SEALED FIBER SENSING CABLE - In one aspect, the present invention provides a hermetically sealed fiber sensing cable comprising: a core fiber comprising at least one Bragg grating region, an outer surface and a length; a fiber cladding in contact with the core fiber along the entire length of the core fiber, the fiber cladding having an outer surface and a length; a carbon layer disposed upon the outer surface of the fiber cladding along the entire length of the fiber cladding, the carbon layer comprising diamond-like carbon; a hydrogen ion absorption layer in contact with the carbon layer, the hydrogen ion absorption layer being disposed on the outer surface of the carbon layer; and an outer sleeve. Also provided in another aspect of the present invention, is a component for a hermetically sealed fiber sensing cable. | 09-01-2011 |
20110242546 | System For Monitoring a Relative Displacement of Components - A system is provided for monitoring a relative displacement of a pair of end-winding components. The system includes a structure mounted to the end-winding components. The system further includes a fiber Bragg grating mounted to a non-curved surface of the structure, where the fiber Bragg grating is configured to reflect incident radiation having a peak intensity at a respective wavelength based on a strain of the fiber Bragg grating. The structure is configured so that the strain produced by the structure limits a magnitude of the strain of the fiber Bragg grating within a predetermined range over a span of the relative displacement of the pair of end-winding components. | 10-06-2011 |
20120029835 | FIBER OPTIC CARBON DIOXIDE PURITY SENSOR PACKAGE AND SYSTEM - A carbon dioxide (CO2) purity sensor package includes a fiber core, a periodic refractive index modulated fiber grating structure within the fiber core and a fiber cladding. A thermally conductive sensing layer is positioned about a portion of the fiber cladding surrounding the periodic refractive index modulated fiber grating structure. A gas chamber encloses the fiber cladding with the thermally conductive sensing layer. | 02-02-2012 |
20130145852 | High Pressure Fiber Optic Sensor System - The present application provides a fiber optic sensor system. The fiber optic sensor system may include a small diameter bellows, a large diameter bellows, and a fiber optic pressure sensor attached to the small diameter bellows. Contraction of the large diameter bellows under an applied pressure may cause the small diameter bellows to expand such that the fiber optic pressure sensor may measure the applied pressure. | 06-13-2013 |
Patent application number | Description | Published |
20090069420 | Small molecule inhibitors of STAT3 with anti-tumor activity - The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S3I-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents. | 03-12-2009 |
Patent application number | Description | Published |
20110201576 | Small molecule inhibitors of stat3 with anti-tumor activity - The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S3I-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents. | 08-18-2011 |
20110201609 | PROTEASOME INHIBITORS FOR SELECTIVELY INDUCING APOPTOSIS IN CANCER CELLS - The subject invention concerns compounds having activity as inhibitors of proteasomes and methods of using the subject compounds. In one embodiment, a compound of the invention has the chemical structure shown in formula I: | 08-18-2011 |
20120142917 | PROTEASOME INHIBITORS HAVING CHYMOTRYPSIN-LIKE ACTIVITY - Disclosed herein is the use of HLM-008182, as well as its analogues formed via in-house synthesis, as a potent proteasome inhibitors. A new method was developed for HLM-008182 through a four-step protocol and the method was further optimized to a two step protocol. The synthesis in both protocols was regioselective with TiCl | 06-07-2012 |
Patent application number | Description | Published |
20130203709 | ACYLSULFONAMIDES AND PROCESSES FOR PRODUCING THE SAME - The present disclosure relates to acylsulfonamides and processes for their preparation. The processes involve a target-guided synthesis approach, whereby a thioacid and a sulfonyl azide are reacted in the presence of a biological target protein, a Bcl-2 family protein, to form the acylsulfonamide. | 08-08-2013 |
20140329900 | SMALL MOLECULE INHIBITORS OF STAT3 WITH ANTI-TUMOR ACTIVITY - The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S31-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents. | 11-06-2014 |