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Guerin, US
David J. Guerin, Natick, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090048429 | Processes and intermediates - The invention relates to processes and compounds useful for producing modified aspartic acid derivatives, such as aspartic acid aldehyde moieties. Aspartic acid derivatives are useful for preparing caspase inhibitors and/or prodrugs thereof. | 02-19-2009 |
| 20090149467 | Tyrosine Kinase Inhibitors - The present invention relates to pyridinyloxy- and pyrimidinyloxyindole derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 06-11-2009 |
| 20090197908 | Benzocycloheptapyridines as inhibitors of the receptor tyrosine kinase met - The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine compounds, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 08-06-2009 |
| 20100160309 | INHIBITORS OF JANUS KINASES AND/OR 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 - The instant invention provides for compounds that inhibit JAK2 tyrosine kinase and/or PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting JAK2 tyrosine kinase activity and/or PDK1 kinase inhibitory activity by administering the compound to a patient in need of treatment or prevention of myeloproliferative disorders or cancer. | 06-24-2010 |
| 20100210623 | THERAPEUTIC COMPOUNDS - The present invention relates to pyrazine substituted pyrrolopyridines which are inhibitors of JAK kinases (JAK1, JAK2, JAK3 and/or TYK2) and/or PDK1 and are thus useful for the treatment of myeloproliferative disorders or cancer. | 08-19-2010 |
| 20110071298 | Processes and Intermediates - The invention relates to processes and compounds useful for producing modified aspartic acid derivatives, such as aspartic acid aldehyde moieties. Aspartic acid derivatives are useful for preparing caspase inhibitors and/or prodrugs thereof. | 03-24-2011 |
David Joseph Guerin, Natick, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110245205 | AMINOPYRIMIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 10-06-2011 |
Frederic Guerin, Arthur, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20080214741 | Process for the Preparation of Low Molecular Weight Hydrogenated Nitrile Rubber - The present invention relates to a process for the production of hydrogenated nitrile rubber polymers having lower molecular weights and narrower molecular weight distributions than those known in the art in the characterized that the process is carried out in the presence of hydrogen and optionally at least one co-(olefin). | 09-04-2008 |
| 20080214758 | Process for the Preparation of Low Molecular Weight Nitrile Rubber - Nitrile rubber polymers, optionally hydrogenated, having lower molecular weight and narrower molecular weight distribution than those known in the art, are prepared by metathesis of nitrile butadiene rubber, optionally followed by hydrogenation. The process comprises the steps of a) reacting a nitrile rubber in the presence of at least one compound which is a ruthenium or osmium based indenylidene complex and optionally b) hydrogenating the resulting lower molecular weight nitrile rubber using standard techniques known in the art. The optionally hydrogenated nitrile rubber, with lower molecular weight and narrower molecular weight distribution has very good heat resistance, excellent ozone and chemical resistance and excellent oil resistance. It is used in automotive, oil, electrical, mechanical engineering and shipbuilding industries. | 09-04-2008 |
John T. Guerin, Bioomfield, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20120091963 | BATTERY FAULT TOLERANT ARCHITECTURE FOR CELL FAILURE MODES PARALLEL BYPASS CIRCUIT - A by-pass circuit for a battery system that disconnects parallel connected cells or modules from a battery circuit or controls the current through the parallel connected cells or modules. If a cell has failed or is potentially failing in the system, then the by-pass circuit can disconnect the cell or module from other cells or modules electrically coupled in parallel. If a cell or module has a lower capability than another cell or module, then the by-pass circuit can control the current to the cell or module to maximize the performance of the system and prevent the system from creating a walk-home condition. | 04-19-2012 |
John T. Guerin, Bloomfield, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20120091964 | BATTERY FAULT TOLERANT ARCHITECTURE FOR CELL FAILURE MODES SERIES BYPASS CIRCUIT - A battery cell by-pass circuit that has particular application for by-passing cells in a high voltage battery for a vehicle. The battery includes a plurality of battery cells electrically coupled in series. The by-pass circuit includes a first switch electrically coupled in series with one or more of the battery cells, a by-pass line electrically coupled around the one or more battery cells and a second switch electrically coupled in the by-pass line and in parallel with the one or more battery cells. During normal cell operation, the first switch is closed and the second switch is open so that current flows through the one or more battery cells. If the one or more battery cells fail or are failing, the first switch is opened and the second switch is closed so that current by-passes the one or more cells and they are removed from the battery circuit. | 04-19-2012 |
John Thomas Guerin, Bloomfield, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100198754 | METHOD OF PROVIDING MODULAR BATTERY PACKS FOR A HYBRID VEHICLE - A method of offering or providing batteries for a hybrid or electric vehicle allows the customer to choose a vehicle electrical battery power rating that will match their expected driving range needs. Specifically, the method includes offering different modular battery packs for an electric or hybrid electric vehicle. Each of the different modular battery packs has a different number of interconnected batteries, a different energy level, and is configured to be operable for providing propulsion power to the vehicle. At least one of the different modular battery packs is installed on the hybrid or electric vehicle. The method may include recharging and/or recycling used battery back modules. | 08-05-2010 |
Nicolas Guerin, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120134012 | PERIODICALLY POLED OPTICAL WAVEGUIDE - A periodically poled optical waveguide comprising a nonlinear optical crystalline material is provided having poled optical domains slanted with respect to direction of propagation of light within the waveguide. Light reflected from slanted poled optical domains does not couple efficiently back into the optical waveguide, which facilitates reduction of backreflection towards a semiconductor laser source coupled to the waveguide. Reduction of backreflections facilitates stable operation of the semiconductor laser source. A method of manufacturing of a periodically poled optical waveguide with slanted poled domains is also provided. | 05-31-2012 |
Nicolas Guerin, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080212916 | Polarization Maintaining Fiber Pigtail Assembly - The invention provides a fiber pigtail assembly wherein a polarization maintaining fiber is soldered directly to a mounting pad without a sleeve or a ferrule therebetween. A portion of the polarization maintaining fiber near a fiber end is embedded in a vertical slow axis orientation within an asymmetrical solder ball having a flat portion for adhering to the mounting pad. The vertical slow axis orientation of the polarization maintaining fiber within the solder ball enhances power stability and polarization extinction ratio properties of optical modules utilizing the invention. | 09-04-2008 |
| 20090067454 | Power Stabilization Of Semiconductor Laser Harmonic Frequency Conversion Modules - The invention relates to a fiber laser and harmonic frequency conversion module incorporating a 90 degree Polarization Maintaining (PM) fiber fusion splice therebetween for providing temperature insensitive power stabilization. The present invention has found that incorporating at least one 90 degree splice of the transmission axes of the PM fiber, coupling a fast axis to a slow axis, to create substantially equal optical path lengths of the two transmission axes of the fiber coupling can nearly eliminate output amplitude fluctuation within a practical operating temperature range. | 03-12-2009 |
Roch Guerin, Newtown Square, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090196184 | METHOD AND SYSTEM FOR PATH IDENTIFICATION IN PACKET NETWORKS - A method and system for extracting and building end-to-end route information in a multi-area Internet protocol (IP) autonomous system (AS) is disclosed. The method and system enable a user, such as a network administrator, to explicitly identify a full set of paths (links and routers) that a given IP packet would potentially traverse from its entry point in the source area of the AS where it originates until its exit point in its intended destination area. | 08-06-2009 |
| 20110296051 | ROUTE AWARE NETWORK LINK ACCELERATION - A method and apparatus for route aware network link acceleration provides a managed communication channel for accelerated and reliable network communication between a client and other network devices as needed. The communication channel may comprise one or more segments having increased speed, reliability, security, or other improved characteristics as compared to traditional communication links. Network traffic may be routed through one or more of the segments based on various criteria to improve communication of the traffic. In one embodiment, the segments may be arranged in a daisy chain configuration and be provided by one or more chaining nodes. | 12-01-2011 |
| 20120106337 | DEVICE AND METHOD FOR ONLINE COMPUTATION OF THE FEASIBLE RATES REGION OF A RAMDOM ACCESS NETWORK - A method is intended for computing online a feasible rates region in a network using a random access MAC protocol and comprising nodes having links there between. This method comprises the steps of i) determining, for each link, a primary extreme point corresponding to a maximum output rate when this link transmits alone at a maximum input rate, and ii) determining secondary extreme points by combining these primary extreme points with a chosen interference model, these primary and secondary extreme points defining a boundary of a feasible rates region. | 05-03-2012 |
| 20120113836 | DEVICE AND METHOD FOR COMPUTATION OF CHANNEL LOSS RATE AND COLLISION LOSS RATE OF COMMUNICATION LINK(S) IN A RANDOM ACCESS NETWORK - A method is intended for computing online channel loss rate and collision loss rate of at least one communication link established between nodes of a network using a random access MAC protocol. This method comprises the steps of i) dividing time in probing windows and transmitting a chosen number S of probe packets during each probing window from a transmitter node to a receiver node linked therebetween, ii) measuring a packet loss rate from probe packets lost on this communication link during a probing window, iii) scanning each probing window with smaller sliding windows, each having a size Wk smaller than S, to identify the sliding window during which only channel losses occur, and then for computing a channel loss rate on this communication link from this identified sliding window, and iv) computing a collision loss rate on this communication link by subtracting the computed channel loss rate from the measured packet loss rate. | 05-10-2012 |
Stephen R. Guerin, Milford, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20110174765 | Deformation-Resistant Plastic Aerosol Container - A plastic aerosol container includes a plastic base portion and a plastic main body portion that is unitary with the plastic base portion and defines a longitudinal axis. The base portion and the main body portion together define an internal space within the container that is pressurized with an aerosol mixture at a pressure that is substantially within a range of about 50 psi to about 300 psi at room temperature. The main body portion has an upper portion that has a first maximum transverse diameter, a lower portion that has a second maximum transverse diameter and an intermediate portion that has a third maximum transverse diameter. The third minimum transverse diameter is less than both the first and second maximum transverse diameters, whereby the main body portion has a narrowed waist portion that provides reinforcement against deformation as a result of pressurization within the internal space of the container. The narrowed waist portion preferably has a substantially constant radius of curvature. | 07-21-2011 |
| 20110174827 | Plastic Aerosol Container With Footed Base - A plastic aerosol container includes a main body portion and a base portion, both of which are fabricated from a plastic material such as polyethylene terephthalate. The main body portion has a longitudinal axis and a maximum transverse diameter. The base portion is unitary with the main body portion and has a plurality of feet that are adapted to support the container on a horizontal surface. A first rib that is positioned between adjacent feet preferably has a substantially constant radius of curvature that has a ratio with respect to the maximum transverse diameter that is substantially within a range of about 0.20 to about 1.0. The main body portion and the base portion define an interior space that is pressurized with an aerosol mixture at a pressure that is substantially within a range of about 50 psi to about 300 psi. | 07-21-2011 |