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Gubler, US
Duane J. Gubler, Fort Collins, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20090010961 | Avirulent, immunogenic flavivirus chimeras - Chimeric flaviviruses that are avirulent and immunogenic are provided. The chimeric viruses are constructed to contain amino acid mutations in the nonstructural proteins of a flavivirus. Chimeric viruses containing the attenuation-mutated nonstructural genes of the virus are used as a backbone into which the structural protein genes of a second | 01-08-2009 |
| 20100255030 | AVIRULENT, IMMUNOGENIC FLAVIVIRUS CHIMERAS - Chimeric flaviviruses that are avirulent and immunogenic are provided. The chimeric viruses are constructed to contain amino acid mutations in the nonstructural viral proteins of a flavivirus. Chimeric viruses containing the attenuation-mutated nonstructural genes of the virus are used as a backbone into which the structural genes of a second flavivirus strain are inserted. These chimeric viruses elicit pronounced immunogenicity yet lack the accompanying clinical symptoms of viral disease. The attenuated chimeric viruses are effective as immunogens or vaccines and may be combined in a pharmaceutical composition to confer simultaneous immunity against several strains of pathogenic flaviviruses. | 10-07-2010 |
Jeffery V. Gubler, Springville, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20110048266 | Crafting Apparatus Including a Workpiece Feed Path Bypass Assembly and Workpiece Feed Path Analyzer - A method of operating a crafting apparatus. The method includes moving a workpiece along a first feed path for printing on the workpiece with a printer and moving the workpiece along a second feed path for cutting the workpiece with a cutter. The first feed path bypasses a workpiece mover of the cutter. | 03-03-2011 |
| 20110052301 | (Moab Omnibus-Apparatus) Crafting Apparatus Including a Workpiece Feed Path Bypass Assembly and Workpiece Feed Path Analyzer - A crafting apparatus that includes a body defining at least one passageway for receiving a workpiece, a cutter disposed along the at least one passageway, a printer disposed along the at least one passageway and spaced from the cutter, and a feed path bypass assembly disposed along the at least one passageway between the cutter and the printer. The feed path bypass assembly alters a feed path of the workpiece through the at least one passageway. | 03-03-2011 |
Jeffrey V. Gubler, Springville, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20100064911 | EMBOSSING DEVICE AND METHODS FOR USING AND MANUFACTURING THE SAME - An assembly is disclosed. The assembly includes an embossing device including a blank portion workpiece including a plurality of layers, wherein the blank portion workpiece is separated to include a first blank portion and a second blank portion, wherein each of the first and second blank portions include portions of at least two layers of the plurality of layers; and a blank portion retainer including a first flap and a second flap, wherein the first flap and the second flap are connected by a member consisting of a hinge, wherein the hinge and the first flap and the second flap define a folder, wherein each of the first and second flaps define an inner surface and an outer surface, wherein the first blank portion is attached to the inner surface of the first flap, wherein the second blank portion is attached to the inner surface of the second flap | 03-18-2010 |
| 20110073519 | Decorative Object Arrangement Device and Method for Utilizing the Same - An arrangement device is disclosed. The arrangement device includes a tray portion having a body that forms a plurality of passages. The arrangement device also includes a plurality of pattern adjustment plungers movably-secured to the tray portion within the plurality of passages. | 03-31-2011 |
Ulrich A. Gubler, Glen Ridge, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090298756 | FUNCTIONS AND USES OF GPR39 GENE IN MAMMALIAN CENTRAL NERVOUS SYSTEM - The present invention provides mammalian GPR39 gene, its coded products, and the uses in regulating appetite and pain sensitivity. A pharmaceutical composition and a health product comprising GPR39 protein are also provided. The health product and the pharmaceutical composition for suppressing appetite or decreasing pain sensitivity comprise a safe and efficient amount of antagonists of mammalian GPR39 protein (for example, 0.01-99%) and a bromatologically or pharmaceutically acceptable carrier in a suitable amount (for example 1-99.99 wt %). | 12-03-2009 |
Ulrich Andreas Gubler, Glen Ridge, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100261191 | STABLE CELL LINES EXPRESSING HERG - A stable eukaryotic cell line that expresses hERG and exhibits a stable current under electrophysiological test conditions is provided. | 10-14-2010 |