Guarna
Antonio Guarna, Sesto Fiorentino IT
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20110237577 | BICYCLIC PEPTIDOMIMETIC INHIBITORS OF ASPARTYL-PROTEASES FOR THE TREATMENT OF INFECTIOUS DISEASES - The present invention refers to 3-aza-bicyclo[3.2.1]octane derivatives of general formula (I) their preparation, use and pharmaceutical compositions useful in the treatment of pathologies associated with microbial pathogens expressing aspartyl-protease activity. | 09-29-2011 |
Antonio Guarna, Seravezza IT
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20130040964 | 1,2,3-TRIAZOLE-BASED PEPTIDOMIMETIC INTEGRIN INHIBITORS FOR THE DIAGNOSIS AND THERAPY OF TUMORS - The present invention refers to the field of chemical compounds bearing a 1,2,3-triazole ring of formula (I) and possessing guanidino and carboxylic groups or their isosteres, their preparation by Cu-catalyzed “click-chemistry”, and medical-diagnostic use in pathologies where angiogenesis is altered, for example pathologic conditions of tumor origin, tumor metastasis, osteoporosis, and rheumatoid arthritis. | 02-14-2013 |
20130136764 | PREPARATION OF CONJUGATES COMPRISING ADENINE DERIVATIVES AND ALLERGENIC PROTEINS AND THEIR USE FOR SPECIFIC IMMUNOTHERAPY OF ALLENGENIC DISEASES - The present invention refers to the preparation of adenine derivative active esters of formula (I) and use thereof for the preparation of stable conjugates between adenine derivative and allergenic proteins having general structure (II) for the modulation of T | 05-30-2013 |
20150080388 | COMPOUNDS FOR THE TREATMENT OF ISCHEMIA-REPERFUSION-RELATED DISEASES - The present invention relates to compounds of formula (I) useful in the treatment of ischemia-reperfusion-related pathologies. | 03-19-2015 |
Antonio Guarna, Milano IT
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20100087326 | HETEROCYLIC COMPOUNDS CONTAINING THE MORPHOLINE NUCLEUS THEIR PREPARATION AND USE - Herein are described heterocyclic compounds containing the morpholine nucleus prepared from amino acids, their preparation and use for therapeutic applications. | 04-08-2010 |
Antonio Guarna, Serravezza IT
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20100324294 | PROCESS FOR THE PREPARATION OF 2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLIN-3-CARBOXYLIC ACID ESTERS - The present invention relates to the process of preparation of 2,3,4,9-tetrahydro-1/−/-β-carbolin-3-carboxylic acid esters substituted in position 1 of the general formula (I). in the preferred diastereoisomeric form through a single step starting from tryptophan in racemic form and/or its enantiomers and from 3,4-(methylenedioxy)benzaldehyde. | 12-23-2010 |
Francesco Guarna, Prato IT
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20110137094 | PROCESS FOR PRODUCING ETHYLIDENE NORBORNENE - Process for producing ethylidenorbornene (ENB) comprising a stage of thermal cracking of DCPD to CPD carried out in an inert fluid to which it is fed a stream of DCPD comprising virgin DCPD from cracking containing up to 10% wt of tetrahydroindene (THI) and recycled DCPD containing THI coming from the subsequent stage of formation of vinylnorbornene. The contact time of DCPD with the heat transfer fluid is of few seconds and it is sufficient to achieve a conversion of said DCPD ≧95%, with little formation of oligomers. THI is then separated from the heat transfer fluid substantially free from DCPD and enriched in THI to a fractionation column. | 06-09-2011 |
Maria Marta Guarna, Vancouver CA
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20150343015 | ANTIMICROBIAL AND ANTI-INFLAMMATORY PEPTIDES - Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally. | 12-03-2015 |
Vince Guarna, Mundelein, IL US
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20100177600 | SYSTEM AND METHOD OF INCREASING BATTERY LIFE OF A TIMEKEEPING DEVICE - Methods and systems of extending battery life of remote battery-operated timekeeping devices by minimizing the number of required synchronizations per unit of time needed to maintain a predetermined accuracy of the devices. The number of synchronizations are minimized by first calculating a time error rate between the remote timekeeping device and a master device over a sample period. Then, a synchronization is delayed and the remote timekeeping device is compensated based on the time error rate. The compensation delays the need for a synchronization yet maintains the predetermined accuracy of the remote timekeeping device. In some embodiments, the remote timekeeping device is compensated and multiple synchronizations are delayed before a new synchronization is necessary to maintain the predetermined accuracy. | 07-15-2010 |