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Guangping Gao

Guangping Gao, Beijing CN

Patent application numberDescriptionPublished
20090319505TECHNIQUES FOR EXTRACTING AUTHORSHIP DATES OF DOCUMENTS - Various technologies and techniques are disclosed for calculating authorship dates for a document. A portion of a document to select to look for possible authorship dates is determined. The possible authorship dates are extracted from the portion of the document. A revised authorship date of the document is generated using a neural network. The revised authorship date is returned to an application or process that requested the date.12-24-2009
20100228711Enterprise Search Method and System - A system and method for enterprise search includes one or more computer-readable media storing computer-executable instructions that, when executed on one or more processors that perform acts including extracting one or more of term data, personal data and metadata from one or more predetermined resources; retrieving a set of information derived from the extracted term data, personal data and metadata responsive to a query; and receiving feedback responsive to the set of information, the feedback augmenting at least one of the one or more predetermined resources.09-09-2010
20110078188Mining and Conveying Social Relationships - Techniques and tools described herein mine social information from a source and store the social information in a database. Responsive to a search object, the techniques search the stored social information and determine social relationships. The techniques further provide, via a graphical user interface, the social relationships determined from the social information stored in the database. In several embodiments, the techniques enable social relationship feedback.03-31-2011

Patent applications by Guangping Gao, Beijing CN

Guangping Gao, Westborough, MA US

Patent application numberDescriptionPublished
20100186103Isolation Of Novel AAV'S And Uses Thereof - The invention in some aspects relates to isolated nucleic acids, compositions, and kits useful for identifying adeno-associated viruses in cells. In some aspects, the invention provides kits and methods for producing somatic transgenic animal models using recombinant AAV (rAAV) to an animal having at least one transgene that expresses a small interfering nucleic acid or at least one binding site for a miRNA.07-22-2010

Guangping Gao, Rosemont, PA US

Patent application numberDescriptionPublished
20080219954Method for rapid screening of bacterial transformants and novel simian adenovirus proteins - Chimpanzee serotype C68 proteins, peptides, and polypeptide are provided. Also provided are novel adenoviruses derived from these proteins, as well as compositions containing these proteins and methods of using same for immunization and therapy. Further, a rapid method for screening recombinant transformants using a visually detectable method is described.09-11-2008
20090197338Method of Increasing the Function of an AAV Vector - A method of correcting singletons in a selected AAV sequence in order to increasing the packaging yield, transduction efficiency, and/or gene transfer efficiency of the selected AAV is provided. This method involves altering one or more singletons in the parental AAV capsid to conform the singleton to the amino acid in the corresponding position(s) of the aligned functional AAV capsid sequences.08-06-2009
20090215871Simian adenovirus vectors and methods of use - A recombinant vector comprises a simian adenovirus capsid and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.08-27-2009
20090227030Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor - Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles.09-10-2009

Patent applications by Guangping Gao, Rosemont, PA US

Guangping Gao, West Borough, MA US

Patent application numberDescriptionPublished
20110151434ADENO-ASSOCIATED VIRUS (AAV) SEQUENCES AND ISOLATING NOVEL SEQUENCES IDENTIFIED THEREBY - A method for detecting and isolating AAV sequences in a sample of DNA obtained from tissue or cells is provided, which sample contains DNA and proviral AAV. The method involves subjecting the sample containing DNA to amplification via polymerase chain reaction (PCR) using a first set of primers which specifically amplify a first AAV region. The first AAV region is characterized by having at least 250 nucleotides of AAV capsid nucleic acid sequence, a variable sequence flanked by a sequence of at least 18 nucleotides at the 5′ end of the first AAV region and a sequence of at least 18 nucleotides at the 3′ end of the first AAV region. Each of the 5′ and 3′ at least 18 nucleotides is the same over at least 9 consecutive nucleotides relative to corresponding sequences in an alignment of at least two AAV serotypes. Each of the sets of primers consist of a 5′ primer and a 3′ primer. The method is further useful for identifying AAV sequences in the sample by the presence of amplified proviral AAV sequences.06-23-2011