Gu, PA
Baohua Gu, Malvern, PA US
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20090042268 | IMINOSUGAR COMPOUNDS WITH ANTIFLAVIRUS ACTIVITY - An anti-viral compounds effective against viruses belonging to the Flaviviridae family, wherein the anti-viral compounds are 1,5-dideoxy-1,5-imino-D-glucitol derivative compounds having the general formula (I) | 02-12-2009 |
20090137039 | TARGETING OPPOSITE STRAND REPLICATION INTERMEDIATES OF SINGLE-STRANDED VIRUSES BY RNAI - The invention relates to methods and compositions for modulating viral replication through double-stranded RNA-mediated gene silencing (RNAi), wherein the antiviral methods and compositions preferentially target opposite strand replication intermediates of single-stranded RNA viruses. | 05-28-2009 |
20100075993 | SMALL MOLECULE INHIBITORS AGAINST WEST NILE VIRUS REPLICATION - The invention provides flavivirus replication inhibitors of WNV and other flaviviruses, such as, for example, JEV, SLEV, AV, KV, JV, CV, YV, TBEV, DENV-1, DENV-2, DENV-3, DENV-4, YFV and MVEV. The invention further provides pharmaceutical compositions including one or more such flavivirus replication inhibitors. The invention further provides methods of treatment, prevention, inhibition or amelioration of one or more diseases associated with flavivirus replication including administering one or more such inhibitors or pharmaceutical compositions. | 03-25-2010 |
Bin Gu, State College, PA US
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20150044264 | Carbamates from Glycerine Carbonate for Pearlization - Alkyl and/or alkenyl glycerol carbamate prepared by reacting a carbonate selected from the group consisting of glycerol carbonate, diglycerol carbonate, polyglycerol carbonate and mixtures thereof, with an amine of the general formula (I): | 02-12-2015 |
Huiming Gu, Holmes, PA US
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20100216627 | METHOD OF MAKING MIXED METAL OXIDE CERAMICS - A method of making dielectric ceramics containing mixed metal oxides is provided. The method comprises the steps of at least partially coating a metal oxide powder with a metal hydroxide or metal oxide, compacting the coated powder with one or more additional metal compounds or metal compound precursors, and directly sintering the compact in a single step. The method of the invention may be used to avoid occurrence of significant quantities of one or more undesired but thermodynamically or kinetically favored side products. The method of the invention may also be used to synthesize perovskites, in particular lead-magnesium-niobium (PMN), lead-magnesium-niobium-lead-titanium (PMN-PT) perovskites, or lead zirconate titanate (PZT). | 08-26-2010 |
Jason Gu, Pittsburgh, PA US
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20130288378 | Two-Dimensional Electron Gas (2DEG)-Based Chemical Sensors - Sensors for sensing/measuring one or more analytes in a chemical environment. Each sensor is based on a semiconductor structure having an interfacial region containing a two-dimensional electron gas (2DEG). A catalyst reactive to the analyte(s) is in contact with the semiconductor structure. Particles stripped from the analyte(s) by the catalyst passivate the surface of the semiconductor structure at the interface between the catalyst and the structure, thereby causing the charge density in the 2DEG proximate the catalyst to change. When this basic structure is incorporated into an electronic device, such as a high-electron-mobility transistor (HEMT) or a Schottky diode, the change in charge density manifests into a change in an electrical response of the device. For example, in an HEMT, the change in charge density manifests as a change in current through the transistor, and, in a Schottky diode, the change in charge density manifests as a change in capacitance. | 10-31-2013 |
20140061637 | Corrosive Resistant Electronic Components - An electronic device of the type wherein a semiconductor stack is functionally supported by interconnects, electrical contacts and dielectric materials. The interconnects and electrical contacts are composed of iridium, ruthenium, zirconium, niobium, tantalum, rhodium, chromium, nickel, palladium, osmium, platinum, titanium, silver and their alloys. The dielectric materials are formed of mixtures of titanium oxide, zirconium oxide, iridium oxide, silver oxide, ruthenium oxide, and niobium oxide. An adhesion layer may be formed of ruthenium, nickel, iridium, zirconium, titanium, chromium, and alloys thereof | 03-06-2014 |
20140087476 | OPTICAL SENSOR FOR BROMIDE ION - Methods and systems to determine a concentration of bromide ions in an aqueous sample are disclosed. The method involves the oxidation of bromide ions to bromine, followed by bromination of a colored or fluorescent reporter compound which may be detected by spectrophotometric means. The relative change in color or fluorescence upon bromine binding to the reporter compound may then be used to determine a quantitative concentration of bromide ions in the sample. The system utilizes a photocatalytic coating in a sample chamber, a source of reporter compound in fluid communication with the sample chamber, light sources that may activate the photocatalyst and excite the reporter compound, an optical detection unit capable of receiving a light signal from the second light source after it has passed through the sample chamber, and various pumps, valves or injection syringes that regulate the flow of sample and reporter compound into and out of the sample chamber. | 03-27-2014 |
Ming Gu, Yardley, PA US
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20080302957 | IDENTIFYING IONS FROM MASS SPECTRAL DATA - A method for identify isotope patterns in mass spectral data, comprising obtaining a desired mass spectral peak shape function; obtaining mass spectral data composed of actual isotope patterns to be analyzed; calculating theoretical isotope pattern from known elemental composition of at least one basic ion whose isotope pattern is representative of the ions to be analyzed, by using mass spectral peak shape function; comparing quantitatively corresponding parts of the theoretical isotope pattern to that of the mass spectral data; calculating a numerical metric to measure similarity between the theoretical isotope pattern and actually measured isotope pattern; and utilizing the numerical metric as an indication for possible presence of ions whose isotope patterns resemble that of the basic ion. A computer for and a computer readable medium having computer readable code thereon for performing the methods. A mass spectrometer having an associated computer for performing the methods. | 12-11-2008 |
20090076737 | QUALITATIVE AND QUANTITATIVE MASS SPECTRAL ANALYSIS - A method for analyzing data from a mass spectrometer comprising acquiring raw profile mode data containing one or more ions and their isotopes in a mass spectral range; calculating theoretical isotope distributions for all ions of interest including native or labeled ions based on their molecular composition; convoluting the theoretical isotope distributions with target peak shape function specified during instrument calibration, actual peak shape functions, or approximated peak shape functions, to obtain theoretical isotope profiles for all ions; constructing a peak component matrix of relevant theoretical isotope profiles included as peak components; performing a weighted multiple linear regression between the profile mode data and the peak component matrix; and reporting regression coefficients as relative concentrations for each of the ions, or ranking these ions based on fitting statistics as search results. A mass spectrometer system (FIG. | 03-19-2009 |
20090152455 | METHODS FOR CALIBRATING MASS SPECTROMETRY (MS) AND OTHER INSTRUMENT SYSTEMS AND FOR PROCESSING MS AND OTHER DATA - A method for obtaining at least one calibration filter for a Mass Spectrometry (MS) instrument system. Measured isotope peak cluster data in a mass spectral range is obtained for a given calibration standard. Relative isotope abundances and actual mass locations of isotopes corresponding thereto are calculated for the given calibration standard. Mass spectral target peak shape functions centered within respective mass spectral ranges are specified. Convolution operations are performed between the calculated relative isotope abundances and the mass spectral target peak shape functions to form calculated isotope peak cluster data. A deconvolution operation is performed between the measured isotope peak cluster data and the calculated isotope peak cluster data after the convolution operations to obtain the at least one calibration filter. Provisions are made for normalizing peak widths, combining internal and external calibration, and using selected measured peaks as standards. Aspects of the methods are applied to other analytical instruments. | 06-18-2009 |
20090302213 | INTERACTIVE METHOD FOR IDENTIFYING IONS FROM MASS SPECTRAL DATA - A method for identifying ions that generated mass spectral data, comprises acquiring raw mass spectral data in profile mode containing at least one ion of interest; performing at least one of mass spectral calibration involving peak shape and a determination of actual peak shape function associated with the acquired raw mass spectral data; considering at least one possible elemental composition of the ion; calculating theoretical mass spectral data for said elemental composition using the actual peak shape function; performing a normalization between corresponding parts of the theoretical mass spectral data and that of the raw or calibrated mass spectral data; and displaying mass spectral congruence between at least two mass spectra where one spectrum is the normalized version of the other corresponding to said possible elemental composition. The unique display and method assist in readily identifying ions. A data storage medium having computer code thereon for causing a computer to performing the method; also in combination with a mass spectrometer. | 12-10-2009 |
Minghua Gu, Collegeville, PA US
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20110124671 | SPIROINDENES AND SPIROINDANES AS MODULATORS OF CHEMOKINE RECEPTORS - The present invention relates to a compound of the following formula: | 05-26-2011 |
Tianyu Gu, Pittsburgh, PA US
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20150353082 | UNIFIED MOTION PLANNING ALGORITHM FOR AUTONOMOUS DRIVING VEHICLE IN OBSTACLE AVOIDANCE MANEUVER - A method for automated lane centering and/or lane changing purposes for a vehicle traveling on a roadway that employs roadway points from a map database to determine a reference vehicle path and sensors on the vehicle for detecting static and moving objects to adjust the reference path. The method includes reducing the curvature of the reference path to generate a reduced curvature reference path that reduces the turning requirements of the vehicle and setting the speed of the vehicle from posted roadway speeds from the map database. The method also includes providing multiple candidate vehicle paths and vehicle speeds to avoid the static and moving objects in front of the vehicle. | 12-10-2015 |
Xin Gu, University Park, PA US
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20130168321 | NITROGEN-CONTAINING ACTIVATED CARBON MATERIAL - An activated carbon material for removing a contaminant from a liquid. The activated carbon material can be a plurality carbon grains that have a pore volume of approximately 0.1 milliliters per gram (mL/g) in the range of less than about 15 angstroms in width. The carbon grains can also have or contain a nitrogen-containing species having a concentration of more than 2 atomic percent nitrogen. A plurality of the carbon grains can be used to make a contactor that is operable to remove or reduce perchlorate having a concentration of 20 parts per billion (ppb) to less than 4 ppb from 4,500 bed volumes of water with the nitrogen-containing species leaching off of the carbon grains less than 0.1 mg/L. The activated carbon material can also be electrochemically regenerated. | 07-04-2013 |
Yeyi Gu, State College, PA US
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20140363529 | COMPOUNDS INFLUENCING FATTY ACID UPTAKE AND METABOLISM AND METHODS OF ISOLATING FROM COCOA PRODUCTS - The invention provides compounds and plant extract compositions that inhibit pancreatic enzymes, such as lipases and amylases, and most particularly pancreatic lipase and phospholipase A | 12-11-2014 |