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Grossi, US

Aldo P. Grossi, Wallingford, PA US

Patent application numberDescriptionPublished
20090100498METHOD AND SYSTEM FOR ANALYZING POLICIES FOR COMPLIANCE WITH A SPECIFIED POLICY USING A POLICY TEMPLATE - A method and system are disclosed for analyzing policies for compliance with a specified policy. The method comprises the steps of creating a policy template representing said specified policy, and comparing a group of given policies to said policy template to determine whether said given policies conflict with said specified policy. In the preferred embodiment of the invention, the specified policy may include specified rules, the given policies include a plurality of given rules, and the policy template expresses said specified rules. In this preferred embodiment, the comparing step includes the step of comparing said plurality of given rules to the policy template to determine whether any of said given rules conflicts with said specified rules. In addition, preferably, if conflicts are found between said given policies and said specified policy, the given policies are modified to eliminate the conflicts.04-16-2009

Alessandro Grossi US

Patent application numberDescriptionPublished
20120080738SHALLOW TRENCH ISOLATION FOR A MEMORY - In some embodiments, a gate structure with a spacer on its side may be used as a mask to form self-aligned trenches in a microelectronic memory, such as a flash memory. A first portion of the gate structure may be used to form the mask, together with sidewall spacers, in some embodiments. Then, after forming the shallow trench isolations, a second portion of the gate structure may be added to form a mushroom shaped gate structure.04-05-2012

Alfredo Grossi, Somerville, MA US

Patent application numberDescriptionPublished
20100048489Stable Solid Formulation of A GC-C Receptor Agonist Polypeptide Suitable for Oral Administration - Solid, stable formulations of linaclotide suitable for oral administration are described herein as are methods for preparing such formulations. The formulations described herein contain a polypeptide consisting of the amino acid sequence Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr (“linaclotide”) or a pharmaceutically acceptable salt thereof. The linaclotide formulations described herein are stable and have a sufficient shelf life for manufacturing, storing and distributing the drug.02-25-2010
20100074949Pharmaceutical composition and administration thereof - The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.03-25-2010
20110059903Formulations Comprising Linaclotide - The present invention relates to stable compositions comprising linaclotide, as well as to various methods and processes for the preparation and use of the compositions.03-10-2011
20120009225Stable Solid Formulation of Therapeutic Polypeptides Suitable for Oral Administration - Solid, stable formulations of therapeutic polypeptide suitable for oral administration are described herein as are methods for preparing such formulations. The therapeutic polypeptide formulations described herein are stable and have a sufficient shelf life for manufacturing, storing and distributing the drug.01-12-2012
20120039949Stable Solid Formulations of GC-C Receptor Agonist Polypeptides Suitable for Oral Administration - Solid, stable formulations of GC-C receptor agonist polypeptide suitable for oral administration are described herein as are methods for preparing such formulations. The GC-C receptor agonist polypeptide formulations described herein are stable and have a sufficient shelf life for manufacturing, storing and distributing the drug.02-16-2012

Patent applications by Alfredo Grossi, Somerville, MA US

Eugene Grossi, New York, NY US

Patent application numberDescriptionPublished
20110022169Annuloplasty Device for Tricuspid Valve Repair - Annuloplasty device for implantation adjacent an annulus of a tricuspid valve, the annulus comprising anterior, posterior and septal aspects adjacent anterior, posterior and septal leaflets, respectively, of the tricuspid valve, the device comprising: a ring body comprising: an anterior portion, a posterior portion and a septal portion shaped to conform to, and for implantation adjacent, the anterior, posterior and septal aspects of the annulus, respectively; and first and second end portions that are more flexible than a remainder of the ring body to provide a gradual transition from the remainder of the ring body to tissue of the tricuspid valve annulus; wherein the ring body is curvilinear, with substantially no flat portions, and forming a shape. Related devices, kits and sizer devices.01-27-2011

Fabio G. Grossi, Grapevine, TX US

Patent application numberDescriptionPublished
20090158705Hypermixing Fluid Ejector - The present invention provides a hypermixing fluid ejector. The ejector includes a reservoir containing a primary fluid and an ejector nozzle with a trailing-edge array of rectilinear orifices. The primary fluid is ejected through these orifices to entrain a secondary fluid, thereby creating a mixed fluid flow. A dividing line is defined on the trailing surface of the nozzle that is orthogonal to the linear axis of the ejector, and the orifices alternate above and below this dividing line in an abutting, offset manner. The orifices are geometrically inclined to produce spray cones that are convergent relative to this dividing line, resulting in convergent helical hypermixing of the primary fluid with the secondary fluid.06-25-2009
20090158744Statically-Operating Ejector Ramjet - The present invention provides a statically starting and operating ramjet engine system. The system includes a pumping ejector coupled to a ramjet engine upstream of the ramjet inlet. A subsonic converging nozzle is placed in fluid communication between the pumping ejector and ramjet inlet. The pumping ejector ejects a primary fluid into the ramjet inlet to entrain a secondary fluid and create a mixed flow with sufficient momentum and internal energy to achieve characteristic speed. The converging nozzle provides a characteristic cross section necessary for the mixed flow to achieve characteristic speed as it moves through the nozzle, thereby producing a standing shock wave at the point of maximum convergence of the nozzle and creating sonic conditions at the inlet of the ramjet engine.06-25-2009
20090158745Ramjet Superheater - The present invention provides a regenerative superheater system for an ejector ramjet engine. The invention includes a superheater in thermal communication with the combustion chamber of the ramjet engine. The superheater transfers thermal energy from combustion chamber to an ejectant which is then redirected upstream to the ramjet ejector. In one embodiment of the invention the temperature of the ejectant is modulated by a variable geometry cooler that controls the amount of thermal energy removed from the superheater system by ambient air. In an alternate embodiment of the invention, the temperature of the ejectant is modulated by a variable geometry superheater that controls the amount of thermal energy added to the superheater system through combustion gas.06-25-2009
20090162213Pumping Ejector - The present invention provides a fluid pumping ejector. The ejector includes a reservoir containing a primary fluid and a mixing duct. An ejector nozzle ejects the primary fluid from said reservoir into the mixing duct to entrain a secondary fluid and create a mixed flow with sufficient momentum and internal energy to achieve characteristic speed. A subsonic converging nozzle is coupled to the mixing duct downstream of the ejector nozzle and provides a characteristic cross section necessary for the mixed flow to achieve characteristic speed as it moves through said converging nozzle, thereby producing a standing shock wave at the point of maximum convergence of the nozzle. The ejector nozzle is fully-expanded, wherein exit speed of the primary fluid is supersonic and exit static pressure of the primary fluid is equal to secondary fluid pressure.06-25-2009

Federico V. Grossi, Louisville, KY US

Patent application numberDescriptionPublished
20090202621CELL-SURFACE DECORATION WITH ACTIVE AGENTS - A lipid vesicle comprising a functionalized lipid comprising a tether moiety having binding affinity for a ligand portion of an active agent and the active agent are provided. Methods of decorating endothelial cells, tissues, and organs with active agents utilizing the disclosed lipid vesicles are also provided.08-13-2009

James Grossi, Gustine, CA US

Patent application numberDescriptionPublished
20090316515Method And Apparatus For Highly Controlled Color Distribution In Mass Produced Concrete Products - A method and apparatus for highly controlled color composition and distribution within the face mix of semi-dry concrete mix paving stones.12-24-2009