Grosse
Alexandre D. Grosse, Iowa City, IA US
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20110219789 | FAST ICE MAKING DEVICE - A refrigerator includes a fast ice making device for quickly producing ice cubes. The fast ice making device includes a mold body having a plurality of ice forming cavities adapted to hold fluid. In an ice making cycle, a vacuum system evacuates air from the cavities, thereby depressurizing the cavities. Then, a liquid delivery system delivers liquid to the depressurized cavities, whereby an initial portion of the liquid bubbles up within the respective cavities. Overall, a cooler fluid is established at the beginning of an ice making cycle, thus accelerating the rate at which ice cubes are formed within the fast ice making device. Once ice cubes have been formed within the cavities, a heat transfer system is utilized to heat the cavities, thereby slightly melting the ice cubes and aiding in the expulsion of ice cubes from the cavities. | 09-15-2011 |
Amanda Grosse, New York, NY US
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20140012614 | DUE DILIGENCE SYSTEMS AND METHODS - A system for performing due diligence on electronically stored documents is provided. A dynamic due diligence item (DDDI) is created by one user and associated with a particular document or piece of information by the system. The created DDDI is assigned to another user. The created DDDI is then routed by the system over a computer network to another user for review of the DDDI and the associated particular document or piece of information. In certain instances, after receiving the notification and opening the document, the system may enforce upon the second user a required action when the DDDI is presented. | 01-09-2014 |
20140013242 | COLLABORATIVE DUE DILIGENCE REVIEW SYSTEM - A system for providing a virtual data room for conducting due diligence on a plurality of documents that are remotely located and accessible over a computer network by a plurality of users using client computer systems. Documents are retrieved from the remote system and presented to a user on their local computing system for review and conducting due diligence tasks thereon. Based on the interaction the user has with the displayed document, due diligence status values that are associated with the display document are updated and stored with the virtual data room system. A display request is received and based on the request a display characteristic is calculated for a folder that includes a set of documents. The display characteristic is determined based on the due diligence status values of all of the documents within the folder. | 01-09-2014 |
Eric Henry Grosse, Berkeley Heights, NJ US
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20080212597 | Method and apparatus for filtering data packets - Disclosed is a method and apparatus for filtering received data packets. A hierarchical tree is maintained. The tree includes nodes organized in a plurality of levels. Each level above a root node of the tree has one or more of the nodes, with each of the one or more of the nodes corresponding to a particular value of a segment of an Internet Protocol (IP) address. The segment is the same for each node of a particular level of the tree. Each node at a particular level of the tree stores a number representative of the number of received packets having the same value for the segment of the IP address associated with the particular level. Some of the received data packets are filtered out based on the hierarchical tree. | 09-04-2008 |
Jason C. Grosse, Vancouver, WA US
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20090026265 | DETERMINING A POSITION OF A PRINT CARRIAGE - A system is provided that includes an encoder strip having encoder markings and at least a first index marking along a length of the encoder strip, an encoder configured to generate a first signal that indicates detection of the encoder markings in response to being moved along the length of the encoder strip, an index sensor configured to generate a second signal that indicates detection of the first index marking in response to being moved along the length of the encoder strip in unison with the encoder, and processing circuitry configured to determine a first encoder index value that corresponds to a center of the first index marking using the first and the second signals. | 01-29-2009 |
Jason Charles Grosse, Vancouver, WA US
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20080225103 | Systems and Methods for Adjusting Loading of Media Onto A Print Surface - In one embodiment, a system and method pertains to detecting a position of a sheet of media that has been loaded onto the print surface, determining from the detected position a current loading error with which the media sheet has been loaded onto the print surface, and calculating a loading offset that can be used to adjust the position at which a future media sheet will be loaded onto the print surface. | 09-18-2008 |
20080228293 | System and method for tuning positioning mechanisms for printing apparatus - A method of controlling parameters of a positioning mechanism of a printer comprises calculating a deceleration profile of decaying velocity versus position function by defining the function to represent a specimen motor velocity decay from a maximum velocity to zero velocity over a period during which zero voltage is applied to the specimen motor; and moving a load using the positioning mechanism and the calculated deceleration profile between positions and determining parameter values based on an iterative process. | 09-18-2008 |
Joerg Grosse, Santa Cruz, CA US
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20090222774 | Method for evaluating the quality of a computer program - The invention relates to a method for rating the quality of a computer program whose execution involves an integrated circuit's input data and output data being influenced, comprising | 09-03-2009 |
Johannes Grosse, Cambridge GB
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20090036394 | GRP 146 Receptor - We disclose GPR146 G-protein coupled receptor (GPCR) polypeptides comprising the amino acid sequence shown in SEQ ID NO. 3 or SEQ ID NO: 5, and homologues, variants and derivatives thereof. Nucleic acids capable of encoding GPR146 polypeptide are also disclosed, in particular, those comprising the nucleic acid sequences shown in SEQ ID No. 1A, SEQ ID No.1 B, SEQ ID No.2 or SEQ ID NO: 4. The GPR146 receptor is useful in the diagnosis and therapy of dyslipidaemias. | 02-05-2009 |
20100272727 | COMPOUND FOR CONTROLLING APPETITE - Insl5 has been found to be orexigenic, i.e. it increases appetite. Insl5, or a derivative or fragment thereof that retains the ability to bind to the GPR100 receptor, or an Insl5 antibody, are useful in therapy, in particular to treat anorexia nervosa, bulimia, cachexia or wasting disease. | 10-28-2010 |
20140161795 | METHOD FOR TREATING A DISEASE CHARACTERIZED BY INCREASED APPETITE - Insl5 has been found to be orexigenic, i.e. it increases appetite. Insl5, or a derivative or fragment thereof that retains the ability to bind to the GPR100 receptor, or an Insl5 antibody, are useful in therapy, in particular to treat anorexia nervosa, bulimia, cachexia or wasting disease. | 06-12-2014 |
John Patrick Grosse, Plymouth, MN US
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20110221217 | Finger-manipulated grasping device - A device for assisting manual grasping of articles, the device having: | 09-15-2011 |
Joshua Grosse, Calgary CA
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20160022205 | SYSTEMS AND METHODS FOR PROVIDING AN AUTOMATED TITRATION FOR ORAL APPLIANCE THERAPY - Provided herein are systems, methods and devices for performing one or more titrations for oral appliance therapy. For example, a method for evaluating an outcome of oral appliance therapy in a subject is discussed herein. The method can include positioning an adjustable mandibular displacement device in an oral cavity of a subject and implementing an automatic titration protocol. The protocol can include controlling a protrusion level of the adjustable mandibular displacement device during a test period, monitoring physiological information from the subject during the test period, and analyzing the physiological information to evaluate the outcome of oral appliance therapy. | 01-28-2016 |
Nicolas Grosse, Strasbourg FR
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20110257998 | INTEROPERABILITY TOOLS AND PROCEDURES TO AGGREGATE AND CONSOLIDATE LAB TEST RESULTS - A method for providing interoperability of laboratory records of a patient is provided. The method includes receiving, using a hardware processor, incoming lab test data at a central server. The incoming lab test data includes a plurality of different formats and is stored on the central server in the formats received. The lab test data is then converted into a unified format to obtain unified format lab test data. The unified format lab test data is then correlated using the hardware processor, based on a healthcare identification code to obtain correlated data and is recorded, using the hardware processor, into a single document. | 10-20-2011 |
Olivier Grosse, Vandoeuvre-Les-Nancy FR
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20130231903 | SYSTEMS AND METHODS FOR GENERATING A GEOLOGICAL MODEL HONORING HORIZONS AND FAULTS - A system and method for modeling a subsurface structure. Data representing a configuration of faults, horizons, and/or unconformities may be transformed to a depositional model comprising cells representing an estimated configuration of subsurface structure at a depositional time period when the subsurface structure was formed. Groups of cells in the depositional model may be divided into sub-meshes using iso-surfaces, where one set of iso-surfaces may represent the horizons at the depositional time period. The sub-meshes may be divided into one or more parts using the transformed geological data representing an estimated depositional configuration of the faults. For each group of cells in each sub-mesh part, the group of cells in the sub-mesh part may be represented by a single polyhedron. The polyhedrons may be transformed to generate a current model to represent the current configuration of the faults and horizons using transformed polyhedrons. | 09-05-2013 |
Philippe Grosse, Sassenage FR
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20080205899 | Optoelectronic Transmitting and Receiving Device - An optoelectronic transmitting and receiving device, including a pierced platform including at least one through hole for introduction of an optical fiber, a first optoelectronic element integral with the platform, arranged substantially facing the through hole and configured to emit or receive a first laser beam at a first wavelength, and at least one second optoelectronic element hybridized on the platform and arranged substantially facing the through hole. The first element is arranged between the platform and the second element, which is configured to receive or emit a second laser beam at a second wavelength, different than the first wavelength, passing through the first element. | 08-28-2008 |
20090262336 | NON-DESTRUCTIVE TESTING OF AN INTEGRATED OPTICAL COUPLER IN AN INTEGRATED OPTICAL CIRCUIT - A non-destructive method for characterizing a surface-illuminated integrated optical coupler associated with an optical waveguide, comprising the steps of measuring the reflection coefficient on a first region of the coupler at a distance from the optical waveguide and constructing a first curve, determining a first model of the reflection coefficient on the first region, performing a first parameter fitting between the first curve and the first model to determine first parameters, measuring the reflection coefficient on a second region of the coupler close to the guide, and constructing a second curve, determining a second model of the reflection coefficient on the second region, performing a second parameter fitting between the second curve and the second model to determine second parameters, and constructing the characteristic of the coupling efficiency of the coupler using the first and second parameters. | 10-22-2009 |
20120087621 | NANOPHOTONIC OPTICAL DUPLEXER - An optical duplexer intended to receive light at a first optical wavelength and to transmit back light at a second optical wavelength, including, on a substrate, successive layers forming a photoreceptor of the first optical wavelength, a selective filter letting through the first optical wavelength, and a waveguide having a surface including a grating which is transparent for the first optical wavelength and diffracting for the second optical wavelength. | 04-12-2012 |
Stefanï Grosse, London GB
Stephan Grosse, Longueuil CA
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20100285569 | Pectate lyases with increased thermostability and/or enzymatic activity - Using site-directed mutagenesis to mutate the | 11-11-2010 |
Stephanie Grosse, London GB
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20100184831 | Materials and Complexes for the Delivery of Biologically-Active Materials to Cells - The invention provides a peptide derivative of formula A-B-C wherein A is a polycationic nucleic acid-binding component; B is a spacer element peptide that is susceptible to cleavage within a cell; and C is a cell surface receptor binding component. The invention also provides a lipid derivative of general formula (I): (PEG) | 07-22-2010 |
Stéphanie Grosse, Saint-Cyr Sur Morin FR
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20130315884 | METHODS FOR ENGINEERING ALLOGENEIC AND IMMUNOSUPPRESSIVE RESISTANT T CELL FOR IMMUNOTHERAPY - Methods for developing engineered T-cells for immunotherapy that are both non-alloreactive and resistant to immunosuppressive drugs. The present invention relates to methods for modifying T-cells by inactivating both genes encoding target for an immunosuppressive agent and T-cell receptor, in particular genes encoding CD52 and TCR. This method involves the use of specific rare cutting endonucleases, in particular TALE-nucleases (TAL effector endonuclease) and polynucleotides encoding such polypeptides, to precisely target a selection of key genes in T-cells, which are available from donors or from culture of primary cells. The invention opens the way to standard and affordable adoptive immunotherapy strategies for treating cancer and viral infections. | 11-28-2013 |
20150017136 | METHODS FOR ENGINEERING ALLOGENEIC AND HIGHLY ACTIVE T CELL FOR IMMUNOTHERAPY - The present invention relates to methods for developing engineered T-cells for immunotherapy that are non-alloreactive. The present invention relates to methods for modifying T-cells by inactivating both genes encoding T-cell receptor and an immune checkpoint gene to unleash the potential of the immune response. This method involves the use of specific rare cutting endonucleases, in particular TALE-nucleases (TAL effector endonuclease) and polynucleotides encoding such polypeptides, to precisely target a selection of key genes in T-cells, which are available from donors or from culture of primary cells. The invention opens the way to standard and affordable adoptive immunotherapy strategies for treating cancer and viral infections. | 01-15-2015 |
20150203817 | USE OF PRE T ALPHA OR FUNCTIONAL VARIANT THEREOF FOR EXPANDING TCR ALPHA DEFICIENT T CELLS - A method of expanding TCRalpha deficient T-cells by expressing pTalpha or functional variants thereof into said cells, thereby restoring a functional CD3 complex. This method is particularly useful to enhance the efficiency of immunotherapy using primary T-cells from donors. This method involves the use of pTalpha or functional variants thereof and polynucleotides encoding such polypeptides to expand TCRalpha deficient T-cells. Such engineered cells can be obtained by using specific rare-cutting endonuclease, preferably TALE-nucleases. The use of Chimeric Antigen Receptor (CAR), especially multi-chain CAR, in such engineered cells to target malignant or infected cells. The invention opens the way to standard and affordable adoptive immunotherapy strategies for treating cancer and viral infections. | 07-23-2015 |
Stéphanie Grosse, Saint-Cyr Sur Morin FR
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20130315884 | METHODS FOR ENGINEERING ALLOGENEIC AND IMMUNOSUPPRESSIVE RESISTANT T CELL FOR IMMUNOTHERAPY - Methods for developing engineered T-cells for immunotherapy that are both non-alloreactive and resistant to immunosuppressive drugs. The present invention relates to methods for modifying T-cells by inactivating both genes encoding target for an immunosuppressive agent and T-cell receptor, in particular genes encoding CD52 and TCR. This method involves the use of specific rare cutting endonucleases, in particular TALE-nucleases (TAL effector endonuclease) and polynucleotides encoding such polypeptides, to precisely target a selection of key genes in T-cells, which are available from donors or from culture of primary cells. The invention opens the way to standard and affordable adoptive immunotherapy strategies for treating cancer and viral infections. | 11-28-2013 |
Thomas Grosse, Holliston, MA US
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20140107803 | ENGINEERED TISSUE SCAFFOLDS AND SUPPORTS THEREFOR - According to some aspects, supports are provided for producing artificial tissue scaffolds. | 04-17-2014 |