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Griffiths

Alan Griffiths, Ascot AU

Patent application numberDescriptionPublished
20080215390PATH DETERMINATION SYSTEM FOR TRANSPORT SYSTEM - Aspects of the present invention relate to path determination for transport system infrastructure paths. In embodiments, methods and systems are provided for identifying alternative paths and determining optimized transport system paths for projects. The methods and systems may involve providing a client-based application having a GUI that presents a plurality of constraints that relate to a project, a server-based application for calculating the costs of a plurality of potential paths for presenting a subset of paths with associated cost data, and determining optimized paths for at least one of a pipeline, a conveyor, a canal, a multipurpose utility pipe, and a telecommunication line.09-04-2008

Alan Lyle Griffiths, Tasmania AU

Patent application numberDescriptionPublished
20100051221METHOD AND APPARATUS FOR MANUFACTURING A PRODUCT OF INTEGRATED CELLULOSE AND FIBROUS MATERIALS - A method and apparatus for manufacturing a product of integrated cellulose and fibrous materials. The method includes blending cellulose particles and polymeric fibres into a cellulose and polymeric fibre blend. The blend is heated to a temperature at which the polymeric fibres begin to melt and to bond with the cellulose particles, so as to form a product of integrated cellulose and fibrous materials. An apparatus for the method includes a first conveying means, a second conveying means, a blending means and a heating means. The apparatus further include a primary shredder and a secondary shredder for shredding the cellulose material, typically recycled newsprint, prior to mixing with the polymeric fibrous material. A shredder is also described.03-04-2010

Andrew Griffiths, Strasbourg FR

Patent application numberDescriptionPublished
20090005254Compartmentalized Screening by Microfluidic Control - The invention describes a method for the identification of compounds which bind to a target component of a bio-chemical system or modulate the activity of the target, comprising the steps of: a) compartmentalising the compounds into micro-capsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsule; and b) identifying the compound which binds to or modulates the activity of the target; wherein at least one step is performed under microfluidic control. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development.01-01-2009
20090068170DROPLET-BASED SELECTION - The present invention generally relates to fluidic droplets, and techniques for screening or sorting such fluidic droplets. In some embodiments, the fluidic droplets may contain cells (e.g., hybridoma cells) that can secrete various species, such as antibodies, for example. In one aspect, a plurality of fluidic droplets containing cells is screened to determine proteins, antibodies, polypeptides, peptides, nucleic acids, or the like. For example, cells able to secrete species such as antibodies may be selected according to certain embodiments of the invention. Examples of such cells include, for instance, immortal cells such as hybridomas, or non-immortal cells such as B-cells. For instance, blood cells may be encapsulated within a plurality of fluidic droplets, and the cells able to produce antibodies may be determined. In some cases, expression or secretion levels may be determined using signaling entities, for example, determinable microparticles present within the fluidic droplet. Other aspects of the invention relate to kits involving such fluidic droplets, methods of promoting the making or use of such fluidic droplets, and the like.03-12-2009
20090176209Selection - The present invention to a nucleotide sequence encoding one or more Arc DNA binding domains, one or more Arc DNA binding sites and at least one polypeptide domain.07-09-2009
20090197772Compartmentalised combinatorial chemistry by microfluidic control - The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules.08-06-2009
20120015382DROPLET-BASED SELECTION - The present invention generally relates to fluidic droplets, and techniques for screening or sorting such fluidic droplets. In some embodiments, the fluidic droplets may contain cells (e.g., hybridoma cells) that can secrete various species, such as antibodies, for example. In one aspect, a plurality of fluidic droplets containing cells is screened to determine proteins, antibodies, polypeptides, peptides, nucleic acids, or the like. For example, cells able to secrete species such as antibodies may be selected according to certain embodiments of the invention. Examples of such cells include, for instance, immortal cells such as hybridomas, or non-immortal cells such as B-cells. For instance, blood cells may be encapsulated within a plurality of fluidic droplets, and the cells able to produce antibodies may be determined. In some cases, expression or secretion levels may be determined using signaling entities, for example, determinable microparticles present within the fluidic droplet. Other aspects of the invention relate to kits involving such fluidic droplets, methods of promoting the making or use of such fluidic droplets, and the like.01-19-2012

Andrew David Griffiths, Strasburg FR

Patent application numberDescriptionPublished
20090197248VITRO EVOLUTION IN MICROFLUIDIC SYSTEMS - The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; and (b) sorting the genetic elements which express the gene product having the desired activity; wherein at least one step is under microfluidic control. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention.08-06-2009

Andrew David Griffiths, Strasbourg FR

Patent application numberDescriptionPublished
20100304378Method for Detecting or Quantifying a Truncating Mutation - The present invention discloses a new method for detecting or quantifying a truncating mutation of a target gene in a subject, said method relying on the in vitro compartmentalization of single genetic constructs in aqueous droplets of a water-in-oil emulsion.12-02-2010

Chad Griffiths, Coquitlam CA

Patent application numberDescriptionPublished
20090052642VOICE AND DATA EXCHANGE OVER A PACKET BASED NETWORK WITH AGC - A signal processing system which discriminates between voice signals and data signals modulated by a voiceband carrier. The signal processing system includes a voice exchange, a data exchange and a call discriminator. The voice exchange is capable of exchanging voice signals between a switched circuit network and a packet based network. The signal processing system also includes a data exchange capable of exchanging data signals modulated by a voiceband carrier on the switched circuit network with unmodulated data signal packets on the packet based network. The data exchange is performed by demodulating data signals from the switched circuit network for transmission on the packet based network, and modulating data signal packets from the packet based network for transmission on the switched circuit network. The call discriminator is used to selectively enable the voice exchange and data exchange.02-26-2009

Craig Griffiths, Surrey CA

Patent application numberDescriptionPublished
20090197032MULTI-LAYER SHEET AND METHOD OF MANUFACTURING SAME - This application relates to a multi-layer sheet suitable for printer infeed comprising a liner sheet and a label sheet. The sheets are bonded together with a dry release coating. The coating may comprise, for example a dry adhesive or the combination of a breakaway coating and an adhesive. In one embodiment the label sheet is formed of transparent plastic and is cut to define a plurality of labels. When a label is removed from the liner sheet, the adhesive remains on the liner sheet and the label is non-tacky Similarly, since the adhesive is quick drying or coated, the dry release coating ensures that the exposed liner layer 08-06-2009

David Gardner Griffiths, Vila Do Bispo PT

Patent application numberDescriptionPublished
20080240856Speed Bump Devices - A speed bump device is provided. The speed bump device comprises a first parallelogram frame, wherein the frame comprises an upper nested beam and a lower nested beam, wherein the upper beam and the lower beam are connected by way of at least one pivotable connecting arm, wherein the lower beam comprises at least one depression and at least one raised section, and wherein the upper beam is displaceable, relative to the lower beam, by way of the at least one connecting arm, from a retracted position, through a maximally extended position, to a raised position. A road surface element may suitably overlie the upper beam.10-02-2008

Gareth Griffiths, Visp CH

Patent application numberDescriptionPublished
20110172419PROCESS FOR THE SYNTHESIS OF CYCLIC CARBAMATES - The invention is directed to a process for the preparation of cyclic carbamates of formula07-14-2011
20120046462PROCESS FOR THE SYNTHESIS OF CHIRAL CYCLIC CARBAMATES - The invention is directed to a process for the preparation of a chiral cyclic carbamate of formula02-23-2012

Hywel David Griffiths, Auckland NZ

Patent application numberDescriptionPublished
20100069492PRODUCTION OF ULTRAPURE EPA AND POLAR LIPIDS FROM LARGELY HETEROTROPHIC CULTURE - Eicosapentaenoic acid (EPA) compositions and EPA-rich polar lipids for prophylactic or therapeutic applications are described. Production from certain cultured micro-organisms (like 03-18-2010

Ian Griffiths, Milano IT

Patent application numberDescriptionPublished
20110249949ASSEMBLY FOR INSTALLING AN OPTICAL ACCESS NETWORK - An assembly for installing an optical access network includes at least one in-line optical cable and a drop cable. The assembly includes a duct suitable for housing the at least one in-line optical cable and an optical transition box for snaking an optical connection between the at least one in-line optical cable and the drop cable. The duct has a window. The optical transition box has a base with two sidewalls. Each of the two sidewalls has a first opening allowing the in-line optical cable to enter and exit the base. The base is suitable for being partially inserted in the duct through the window in such a way that, when the base is partially inserted in the duct, the first opening is contained within the duct.10-13-2011

Ian James Griffiths, Milano IT

Patent application numberDescriptionPublished
20120080651METHOD FOR INSTALLING AN OPTICAL FIBRE UNIT IN A TUBE - A method for installing an optical fibre unit in a protective tube housing a pulling rope includes the steps of: providing a mini tube having a longitudinal opening from end to end; transversally inserting a portion of the pulling rope in the longitudinal opening; contacting the pulling rope and optical fibre unit over a predetermined length; slipping the mini tube over at least a portion of the contacting length of the pulling rope and optical fibre unit; crimping the mini tube around the pulling rope and optical fibre unit; and drawing the optical fibre unit through the protective tube by pulling the pulling rope.04-05-2012

Katherine Merne Griffiths, Eltham AU

Patent application numberDescriptionPublished
20120003214Binding Moieties Based On Shark IgNAR Domains - The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural features derived from IgNAR variable domains.01-05-2012

Katherine Merne Griffiths, Victoria AU

Patent application numberDescriptionPublished
20090148438Binding Moieties Based on Shark Ignar Domains - The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural features derived from IgNAR variable domains.06-11-2009

Katherine R. Griffiths, Hornsby AU

Patent application numberDescriptionPublished
20120094332DNA POLYMERASES AND MUTANTS THEREOF - The present invention provides polypeptides having a nucleotide polymerase activity and method of enhancing polymerase activity. The polypeptides of the present invention may possess both a DNA-dependent DNA polymerase activity and an RNA-dependent DNA polymerase activity, i.e., a reverse transcriptase activity. The polypeptides of the present invention may be used in any application including, but not limited to, DNA sequencing reactions, amplification reactions, cDNA synthesis reactions, and combined cDNA synthesis and amplification reactions, e.g., RT-PCR.04-19-2012

Lynette Robyn Griffiths, Queensland AU

Patent application numberDescriptionPublished
20120004266DOPAMINE-BETA-HYDROXYLASE GENETIC POLYMORPHISM AND MIGRAINE - The invention provides a method of determining whether or not an individual has a predisposition to migraine including the step of determining whether an isolated nucleic acid obtained from the individual comprises a nucleotide sequence corresponding to at least a fragment of a dopamine β-hydroxylase (DBH) gene promoter, wherein the presence of a −1021C→T single nucleotide polymorphism (SNP) in said nucleotide sequence indicates whether or not said individual has an increased predisposition to migraine compared to an individual without the polymorphism. DBH −1021C/C homozygotes are particularly susceptible to migraine. The −1021T allele may exert a protective effect. The method is particularly suited to detection of a predisposition to migraine with aura in females. The invention also provides a diagnostic kit for detecting a −1021C→T SNP associated with migraine. The method and kit may facilitate selection of individuals for migraine therapy which targets the dopaminergic system.01-05-2012

Mansel Griffiths, Rockwood CA

Patent application numberDescriptionPublished
20110262400PROBIOTIC BACTERIAL MOLECULES AND THEIR USE IN METHODS TO TREAT/PREVENT INFECTION BY HARMFUL BACTERIA AND TO PROVIDE NUTRITIONAL HEALTH - This invention provides isolated and characterized secreted molecules from probiotic bacteria for use in compositions and methods for the treatment and/or prevention of infection by harmful pathogenic bacteria. The isolated secreted molecules can also be used in nutritional or medical food products which provide probiotics to the gastrointestinal tract of a mammal.10-27-2011

Neil Griffiths, Rijswijk NL

Patent application numberDescriptionPublished
20100139388Monitoring fluid pressure in a well and retrievable pressure sensor assembly for use in the method - A method for monitoring the pressure difference across an ESP comprises:—connecting the ESP (06-10-2010

Owen Griffiths, Brisbane AU

Patent application numberDescriptionPublished
20100268447SYSTEM AND METHOD FOR JOURNEY PLANNING, FINDING K SHORTEST PATHS THROUGH A TIME/SPACE NETWORK - A method and apparatus for selecting a path defining a journey through a time-tabled transportation network comprises determining forming a data set comprising a sequence of K shortest paths through the transportation network from an origin location “o” to a destination location “d”, each path with an increasing cost; and selecting a path from the K shortest paths based upon a filter criteria which may be one not used in the determination of the K shortest paths. The network comprises a public transportation network. The filter criteria not used in the determination of the K shortest paths may be one that does not obey the principal of optimality. The determining step is performed utilizing an algorithm that filters the available paths through the network according to a selected filter criteria plus a selected buffer amount Δ of the filter criteria. The selecting step utilizes only the rankings of the K shortest paths.10-21-2010

Paul William Griffiths, Dorval CA

Patent application numberDescriptionPublished
20110195370Dental Retainer Having Improved Joint - The invention relates to a dentition retaining apparatus that includes a joint between a holding member and a supporting member. The holding member is elastically deformable and terminates in an end segment having a length with an outer diameter. The joint includes a coil extending from the supporting member and having an inner diameter that is less than the outer diameter of the end segment of the holding member. The coil is placed around at least a portion of the end segment of the holding member. The coil compresses the end segment of the holding member.08-11-2011

Peter Murray Griffiths, Hamilton NZ

Patent application numberDescriptionPublished
20110209883ANIMAL SHOE - The present invention relates to a shoe for an animal characterised in that the material for fabrication of the show has properties similar to, or identical to a homogenous block of ethylene vinyl acetate (EVA) foam, wherein the type of EVA foam is selected from 190 EVA to 450 EVA.09-01-2011

Robert Irwin Griffiths, Beaconsfield Upper AU

Patent application numberDescriptionPublished
20110098608DETECTION OF HYPOKINETIC AND HYPERKINETIC STATES - The present invention relates to an automated method of determining a kinetic state of a person. The method obtains accelerometer data from an accelerometer worn on an extremity of the person and processes the accelerometer data to determine a measure for the kinetic state. The present invention further relates to a device for determining a kinetic state of a person. The device comprises a processor configured to process data obtained from an accelerometer worn on an extremity of the person and to determine from the data a measure for the kinetic state. In the method and system the kinetic state is at least one of bradykinesia, dyskinesia, and hyperkinesia.04-28-2011

Roger Griffiths, Schaffhausen CH

Patent application numberDescriptionPublished
20090260880Method for determining a set of net present values to influence the drilling of a wellbore and increase production - A method is disclosed for modeling a first reservoir while drilling a wellbore into a corresponding second reservoir, the first reservoir having a plurality of stations, comprising: determining a plurality of values of net present value corresponding, respectively, to the plurality of stations of the first reservoir; and drilling the wellbore into the corresponding second reservoir in accordance with the plurality of values of net present value.10-22-2009
20100187412SIGMA MEASUREMENT DOWNHOLE - A downhole tool and method for performing a base log sigma measurement of a formation. The tool comprising a nuclear source for irradiating the formation and a detector for obtaining a sigma measurement of the irradiated formation. The tool is mounted close to a drill bit arranged to drill a borehole into the formation and is capable of determining a base log sigma measurement of the formation while drilling into the formation.07-29-2010

Roger Griffiths, Abu Dhabi AE

Patent application numberDescriptionPublished
20090139713METHOD AND APPARATUS FOR DETECTING WHILE DRILLING UNDERBALANCED THE PRESENCE AND DEPTH OF WATER PRODUCED FROM THE FORMATION - The invention relates to methods and apparatus for determining a downhole parameter in an underbalanced drilling environment which include: selectively activating a first fluid flowing from the formation through a wellbore while under balanced drilled; detecting the activated first fluid, and determining a depth at which said fluid enters the wellbore.06-04-2009

Patent applications by Roger Griffiths, Abu Dhabi AE

Roger Griffiths, Schffhausen CH

Patent application numberDescriptionPublished
20110004408ESTIMATING SIGMA LOG BEYOND THE MEASUREMENTS POINTS - The present disclosure relates to a method to determine the capture cross-section of a subsurface formation at a desired depth in the formation. A database of Sigma values for known lithologies, porosities, and salinities is provided, and multiple Sigma measurements are obtained from a downhole logging tool. Within the database, Sigma values are interpolated to determine the respective depths of investigation of the multiple Sigma measurements. A monotonic function is fitted to the multiple Sigma measurements at the determined depths of investigation, and the capture cross-section of the subsurface formation at any desired depth in the formation is determined using the fitted function. Similarly, a system to determine the capture cross-section of a subsurface formation at a desired depth in the formation and/or a depth of invasion of drilling fluids is also disclosed.01-06-2011

Stephen Griffiths, Thorold CA

Patent application numberDescriptionPublished
20110262256Latching System For Automatically Securing Front-Mounted Loader Mast To Tractor Mounting Frame - A front-mounted loader includes a pair of loader arms each having a rear end pivotally coupled to a loader mast which, in turn, includes lower and upper cross pins respectively located in an upwardly opening and forwardly opening pin receptacles. The forwardly opening receptacle of each loader mounting frame forms a fixed part of a latch assembly defining an upper region of the mounting frame and including latch member mounted for pivoting about a horizontal axis and having a forward nose provided with a downwardly opening receptacle which engages the upper cross pin when the mast is latched to the mounting frame. An over center biasing spring is connected to each latch member and resists movement either from a latching position or an unlatching position. Each mast carries a latch member operating rod which, during detaching the mast from the associated loader mounting frame, acts to engage and move the latch member from its unlatching position, to which it has previously been manually moved, to a latching position once the upper cross pin is moved forwardly from the associated forwardly opening pin receptacle of the mounting frame.10-27-2011

Steven Griffiths, Fredericton CA

Patent application numberDescriptionPublished
20100136038NUCLEIC ACID AND AMINO ACID SEQUENCES OF INFECTIOUS SALMON ANAEMIA VIRUS AND THEIR USE AS VACCINES - The present invention provides the use of nucleic acid sequences and/or amino acid sequences in the preparation of a vaccine for the protection of fish against infectious salmon anaemia virus. Specifically, such vaccines contain at least one nucleic acid sequence which is derived from ISAV or synthetically prepared analogues thereof, or substantially homologous sequences. These nucleic acid sequences are transcripted and translated into peptide sequences which are incorporated into a vaccination strategy to induce and immune response to the surface antigens of ISAV and therefore ISAV itself. Therefore both the use of a vaccine against ISAV, and the incorporation of peptide sequences is herein described.06-03-2010

Steven Griffiths, Monkton CA

Patent application numberDescriptionPublished
20120071630Nucleic Acid and Amino Acid Sequences of Infectious Salmon Anaemia Virus and Their Use as Vaccines - The present invention provides the use of nucleic acid sequences and/or amino acid sequences in the preparation of a vaccine for the protection of fish against infectious salmon anaemia virus. Specifically, such vaccines contain at least one nucleic acid sequence which is derived from ISAV or synthetically prepared analogues thereof, or substantially homologous sequences. These nucleic acid sequences are transcripted and translated into peptide sequences which are incorporated into a vaccination strategy to induce and immune response to the surface antigens of ISAV and therefore ISAV itself. Therefore both the use of a vaccine against ISAV, and the incorporation of peptide sequences is herein described.03-22-2012

Steven Gareth Griffiths, Moncton CA

Patent application numberDescriptionPublished
20090155313Vaccine Against Salmonid Rickettsial Septicaemia Based on Arthrobacter Cells - A vaccine based on live 06-18-2009

Steven Gareth Griffiths, New Brunswick CA

Patent application numberDescriptionPublished
20080287664HSP60 FROM ARTHROBACTER - The hsp60 gene from a strain of 11-20-2008