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Griesbeck
Axel Griesbeck, Köln DE
| Patent application number | Description | Published |
|---|---|---|
| 20110027208 | Photolabile Fragrance Storage Substances - Photolabile fragrance storage substances capable of the photo-induced release of cyclic compounds having semi-cyclic double bonds are described. Further described is a method for sustained scenting of surfaces and a method for production of said fragrance storage substances. | 02-03-2011 |
Axel Griesbeck, Köln DE
| Patent application number | Description | Published |
|---|---|---|
| 20110027208 | Photolabile Fragrance Storage Substances - Photolabile fragrance storage substances capable of the photo-induced release of cyclic compounds having semi-cyclic double bonds are described. Further described is a method for sustained scenting of surfaces and a method for production of said fragrance storage substances. | 02-03-2011 |
Oliver Griesbeck, Munich DE
| Patent application number | Description | Published |
|---|---|---|
| 20090035788 | Genetically encoded bioindicators of calcium-ions - The present invention relates to novel types of cellular calcium probes that are based on Troponin C and two chromophors suitable for FRET (fluorescence resonance energy transfer). The Troponin C-based calcium sensors of the invention function in diverse subcellular environments, for example even when tethered to a cellular membrane. The invention further provides nucleic acid constructs encoding the calcium probes of the invention, expression constructs, host cells and transgenic animals. Furthermore, methods for the detection of changes of local calcium concentrations and for detecting the binding of a small molecule to fragments of Troponin C are provided. | 02-05-2009 |
Oliver Griesbeck, Munchen DE
| Patent application number | Description | Published |
|---|---|---|
| 20110154515 | GENETICALLY ENCODED CALCIUM SENSORS COMPRISING THE C-TERMINAL LOBE OF TROPONIN C AND A FLUORESCENCE TAG - The present invention relates to genetically encoded calcium sensors comprising fluorescent proteins and troponin C as calcium-binding moiety. More specifically, the invention provides a polypeptide comprising a donor moiety for fluorescence resonance energy transfer (FRET), at least two calcium binding moieties derived from the C-terminal domain of troponin C, and an acceptor moiety for FRET. Also, the invention provides nucleic acid molecules, expression vectors, host cells, and transgenic animals. In addition, methods for detecting a change in Ca | 06-23-2011 |