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Greve

Bruce N. Greve, Clarkston, MI US

Patent application numberDescriptionPublished
20120076959EMBLEM ASSEMBLY AND METHOD OF FORMING SAME - An emblem assembly configured for attachment to a vehicle includes a first element having a first surface and a second surface recessed from the first surface, wherein the first element defines at least one void therethrough extending through the second surface. The emblem assembly includes a second element having a third surface, a fourth surface spaced apart from the third surface, and a fifth surface extending between the third surface and the fourth surface, wherein the second surface is spaced apart from the fifth surface to define a channel therebetween. The emblem assembly includes a coating disposed on the third surface and a sealant disposed adjacent and in contact with at least a portion of each of the void, the second surface, the coating, and the fifth surface to thereby fill at least a portion of the channel. A method of forming the emblem assembly is also disclosed.03-29-2012
20120076960EMBLEM ASSEMBLY AND METHOD OF FORMING SAME - An emblem assembly configured for attachment to a vehicle includes a first element and a second element. The first element is configured for attachment to the vehicle and has a first surface and a second surface recessed from the first surface. The second element is configured for attachment to the first element and has a third surface, a fourth surface spaced apart from the third surface, and a fifth surface extending between the third and fourth surfaces, wherein the fifth surface is spaced apart from the second surface to define a channel therebetween. The assembly includes a first coating disposed on the third surface and a tape disposed in contact with at least a portion of each of the second surface, the first coating, and the fifth surface to thereby fill at least a portion of the channel. A method of forming the assembly is also disclosed.03-29-2012

Christopher G. Greve, Covington, LA US

Patent application numberDescriptionPublished
20100272620DRIVE TRAIN FOR AGITATION OF PRODUCTS IN BATCH RETORTS AND RELATED RETORT SYSTEM - A retort system includes a vessel defining a heating chamber and including a product receiving area therein, and a product agitating arm mounted for reciprocating movement through a wall of the vessel and having a first end within the vessel and a second end outside the vessel. A drive arrangement is located exterior of the vessel and operatively coupled to the arm for moving the arm in a reciprocating manner. The drive arrangement includes a crankshaft assembly, a first flywheel and a second flywheel. The crankshaft assembly includes a crank throw operatively coupled to the arm, the crankshaft assembly having a rotational axis offset from the crank throw. The first flywheel is mounted to the crankshaft assembly to a first side of the crank throw for rotation with the crankshaft assembly about the rotational axis. The second flywheel is mounted to the crankshaft assembly to a second side of the crank throw for rotation with the crankshaft assembly about the rotational axis.10-28-2010

Patent applications by Christopher G. Greve, Covington, LA US

Cristian Bernhard Maria Greve, Enschede NL

Patent application numberDescriptionPublished
20100048800METHOD FOR MANUFACTURING A MOULDED ARTICLE WITH INSERT FROM A RUBBER POLYMER - The invention relates to a method for manufacturing a moulded article from a first rubber polymer, which moulded article comprises an insert from a second rubber polymer The method comprises at least the steps of providing a vulcanizing mould with mounting means for the insert, arranging an at least partially vulcanized insert in the vulcanizing mould using the mounting means, adding the first rubber polymer to the vulcanizing mould in unvulcanized state and vulcanizing the moulded article at a suitable vulcanization temperature and subsequently removing the moulded article, with the proviso that prior to step C) at least that side of the insert which comes into contact with the first rubber polymer during step C) is provided with a reactive mixture comprising free radicals. The method is particularly suitable for the manufacture of rubber tyres and spoilers with a coloured insert.02-25-2010

Daniel Rodriguez Greve, Stenlose DK

Patent application numberDescriptionPublished
20080318953Substituted Pyridine Derivatives - The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.12-25-2008
20090118285USE OF KCNQ-OPENERS FOR TREATING OR REDUCING THE SYMPTOMS OF SCHIZOPHRENIA - The invention relates to a novel method for treating or reducing the symptoms of schizophrenia, said method comprising administering to a host in need thereof an effective amount of a compound able to selectively increase the ion flow through KCNQ potassium channels. Furthermore the invention relates to the use of selective KCNQ potassium channel openers for the preparation of a pharmaceutical composition for treating or reducing the symptoms of schizophrenia and related symptoms, disorders and diseases. Furthermore the invention relates to a method of screening for a compound, which is a selective KCNQ potassium channel opener and which is capable of having an anti-psychotic potential.05-07-2009
20100063044SUBSTITUTED ANILINE DERIVATIVES - The present invention relates to aniline derivatives of formula I:03-11-2010
20100137311SUBSTITUTED PYRIMIDINE DERIVATIVES - The present invention relates to pyrimidine derivatives of the general formula I or salts thereof06-03-2010
20110003811SUBSITUTED PYRIDINE DERIVATIVES - The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.01-06-2011

Patent applications by Daniel Rodriguez Greve, Stenlose DK

Frauke Greve, Zurich CH

Patent application numberDescriptionPublished
20090305901High-Throughput Cell-Based Screening System - A (bio-)chemical assay on sensing objects (12-10-2009

Harald Greve, Dusseldorf DE

Patent application numberDescriptionPublished
20110245202PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF RHINITIS - The present invention relates to a pharmaceutical composition suitable for the prophylactic and/or curative topical treatment of rhinitis, said composition containing in combination and in each case in pharmaceutically efficacious amounts:10-06-2011

Harold Greve, Dusseldorf DE

Patent application numberDescriptionPublished
20110257138MONOTERPENES FOR TREATING RESPIRATORY TRACT DISEASES, IN PARTICULAR BRONCHOPULMONARY DISEASES - The invention relates to the combined use of at least one monoterpene which can be applied systemically, in particular perorally, and at least one respiratory tract therapeutic agent which can be applied topically, in particular through inhalation, for the prophylactic and/or therapeutic treatment, in particular combination therapy and/or co-medication, of respiratory tract diseases, in particular bronchopulmonary diseases. Through the combined use of the systemic monoterpene with the topical, in particular inhaled respiratory tract therapeutic agent, the effect or efficiency of the topical or inhaled respiratory disease therapeutic agent can be increased significantly, in particular in a synergistic manner, on the one hand, and the required dosage thereof can be reduced significantly on the other hand, combined with the resulting advantages (e.g., avoidance or reduction of side effects).10-20-2011

Jan Greve, Olenzaal NL

Patent application numberDescriptionPublished
20090311734Laser Illumination System in Fluorescent Microscopy - Devices and methods for automated collection and image analysis are disclosed that enable identification or classification of microscopic objects aligned or deposited on surfaces. Such objects, e.g. detectably labeled rare target cells, are magnetically or non-magnetically immobilized and subjected to Time Delay Integration imaging (TDI). Incorporation of TDI technology into image cytometry analysis, like CellTracks®, makes it possible to image moving objects with very high sensitivity and signal-to-noise ratios. Implementation of TDI camera technology with dual excitation and multispectral imaging of enriched rare cells provides a rapid system for detection, enumeration, differentiation and characterization of imaged rare cells on the basis of size, morphology and immunophenotype.12-17-2009

Jan Greve, Oldenzaal NL

Patent application numberDescriptionPublished
20090286264IMAGING OF IMMUNOMAGNETICALLY ENRICHED RARE CELLS - A method for removing excess unbound ferrofluid and imaging immunomagnetically enriched circulating tumor cells is provided. A vessels having a preformed grooves in the viewing surface is optimally designed for cell alignment and imaging. After separating the unbound particles by centrifugation, an externally-applied force is applied to transport magnetically responsive particle-CTC complex toward the transparent collection wall. The grooved inner surface of the viewing face of the chamber provide uniform distribution of the particles for easy imaging. The invention is also useful in conducting quantitative analysis and sample preparation in conjunction with automated cell enumeration techniques as in quantitative analysis of CTC in disease.11-19-2009
20110044527Methods and Algorithms for Cell Enumeration in a Low-Cost Cytometer - The enumeration of cells in fluids by flow cytometry is widely used across many disciplines such as assessment of leukocyte subsets in different bodily fluids or of bacterial contamination in environmental samples, food products and bodily fluids. For many applications the cost, size and complexity of the instruments prevents wider use, for example, CD4 analysis in HIV monitoring in resource-poor countries. The novel device, methods and algorithms disclosed herein largely overcome these limitations. Briefly, all cells in a biological sample are fluorescently labeled, but only the target cells are also magnetically labeled. The labeled sample, in a chamber or cuvet, is placed between two wedge-shaped magnets to selectively move the magnetically labeled cells to the observation surface of the cuvet. An LED illuminates the cells and a CCD camera captures the images of the fluorescent light emitted by the target cells. Image analysis performed with a novel algorithm provides a count of the cells on the surface that can be related to the target cell concentration of the original sample. The compact cytometer system provides a rugged, affordable and easy-to-use technique, which can be used in remote locations.02-24-2011

Patent applications by Jan Greve, Oldenzaal NL

Jan Greve, Oldenzaal NE

Patent application numberDescriptionPublished
20110052037Methods and Algorithms For Cell Enumeration in a Low-Cost Cytometer - The enumeration of cells in fluids by flow cytometry is widely used across many disciplines such as assessment of leukocyte subsets in different bodily fluids or of bacterial contamination in environmental samples, food products and bodily fluids. For many applications the cost, size and complexity of the instruments prevents wider use, for example, CD4 analysis in HIV monitoring in resource-poor countries. The novel device, methods and algorithms disclosed herein largely overcome these limitations. Briefly, all cells in a biological sample are fluorescently labeled, but only the target cells are also magnetically labeled. In addition, non-magnetically labeled cells are imaged for viability in a modified slide configuration. The labeled sample, in a chamber or cuvet, is placed between two wedge-shaped magnets to selectively move the magnetically labeled cells to the observation surface of the cuvet. An LED illuminates the cells and a CCD camera captures the images of the fluorescent light emitted by the target cells. Image analysis performed with a novel algorithm provides a count of the cells on the surface that can be related to the target cell concentration of the original sample. The compact cytometer system provides a rugged, affordable and easy-to-use technique, which can be used in remote locations.03-03-2011

Jeffrey Michael Greve, Berkeley, CA US

Patent application numberDescriptionPublished
20090010874MODIFIED IL-4 MUTEIN RECEPTOR ANTAGONISTS - This invention relates to modified IL-4 mutein receptor antagonists comprising an IL-4 mutein receptor antagonist coupled to polyethylene glycol. Related formulations and dosages and methods of administration thereof for therapeutic purposes are also provided. These modified IL-4 mutein receptor antagonists, compositions and methods provide a treatment option for those individuals afflicted with a respiratory disorder such as asthma by inhibiting IL-4 and IL-13-mediated airway hyperresponsiveness and eosinophilia. More particularly, these antagonists have an increased duration of effect versus unmodified IL-4RA by virtue of a greater plasma half-life.01-08-2009
20110183920MODIFIED IL-4 MUTEIN RECEPTOR ANTAGONISTS - This invention relates to modified IL-4 mutein receptor antagonists comprising an IL-4 mutein receptor antagonist coupled to polyethylene glycol. Related formulations and dosages and methods of administration thereof for therapeutic purposes are also provided. These modified IL-4 mutein receptor antagonists, compositions and methods provide a treatment option for those individuals afflicted with a respiratory disorder such as asthma by inhibiting IL-4 and IL-13-mediated airway hyperresponsiveness and eosinophilia. More particularly, these antagonists have an increased duration of effect versus unmodified IL-4RA by virtue of a greater plasma half-life.07-28-2011

Patent applications by Jeffrey Michael Greve, Berkeley, CA US

Joachim Greve, Pogeez DE

Patent application numberDescriptionPublished
20090026897SYSTEM FOR THE PRODUCTION OF PREFORMS MADE OF POWDER MATERIAL, IN PARTICULAR TABLETS - System for the production of preforms made of a powder material, in particular tablets, with a rotary tablet press, which is arranged in a housing supported by a frame in the housing, wherein an electric drive motor is integrated into the rotor of the tablet press and the rotor is swivel-mounted on a middle column of the frame, and a control cabinet for the tablet press, which contains among other things a machine computer for the operation of the tablet press, wherein the middle column is supported on a horizontal load-bearing element, which is arranged at a distance above a base plate placed on the floor and the control cabinet is arranged in the interim space between the horizontal load-bearing element and the base plate.01-29-2009

Johannes Wilhelmus Maria Greve, Maastricht NL

Patent application numberDescriptionPublished
20110034376Use of Lipid-Rich Nutrition for the Treatment of Post-Operative Ileus - The invention pertains to the use of a lipid-rich nutrition for the manufacture of a composition for the prevention and/or treatment of post-operative ileus. The lipid fraction inhibited IL-6 and TNF-α levels in peritoneal lavage fluid, and/or wherein the lipid fraction prevents influx of neutrophils in the intestinal muscularis following intestinal manipulation. The nutritional composition comprises at least a lipid fraction which accounts for 42 to 90%, preferably between 45 and 70% of the total energy of the composition. The lipid fraction preferably contains 8 to 50 wt % of phospholipids.02-10-2011

Patent applications by Johannes Wilhelmus Maria Greve, Maastricht NL

Juergen Greve, Ammerich DE

Patent application numberDescriptionPublished
20120078156Compression article with insert - A compression article has an elastic base structure with an insert which is knitted double-ply and applies at least substantially a same compression pressure on a body of a wearer of an article as a base structure.03-29-2012

Matthias Greve, Karlsruhe DE

Patent application numberDescriptionPublished
20080212490Method of Setting Up Connections in a Communication Environment, Communication System and Contact Elemenet for Same - A method of setting up a connection in a communication environment controlled by a communication system between a first node allocated to a first contact and a second node allocated to a second contact includes the steps of providing a contact element within the first node for the first contact, the contact element having graphic and functional properties and graphically representing the second contact, an unambiguous identification and contact data being allocated to the contact element; accessing the contact data using a program and setting up a first connection from the first node to the communication system; checking within the communication system using the unambiguous identification whether the contact element is approved by the communication system for the setting-up of connections; and setting up a second connection to the second node depending on a result of the checking.09-04-2008
20080214214Method and System for Telecommunication with the Aid of Virtual Control Representatives - Method and system of telecommunication between at least two users over a telecommunications network, wherein the first user is connected to the telecommunications network via a first terminal and the second user via a second terminal, and wherein a virtual representative is allocated to each user. A first virtual representative is allocated to the first user and a second virtual representative to the second user. The first and second virtual representatives are presented on the first terminal and on the second terminal. Information is transferred from the first user to the second user and vice versa by an animation of at least one of the first and second representatives and by an interaction between the first and second representatives, wherein at least one of the animation and the interaction takes place in response to a drag & drop command of a user, and wherein an animation of the first virtual representative takes place in response to a command of the first user and an animation of the second virtual representative takes place in response to a command of the second user.09-04-2008

Michael Greve, Karlsruhe DE

Patent application numberDescriptionPublished
20080212490Method of Setting Up Connections in a Communication Environment, Communication System and Contact Elemenet for Same - A method of setting up a connection in a communication environment controlled by a communication system between a first node allocated to a first contact and a second node allocated to a second contact includes the steps of providing a contact element within the first node for the first contact, the contact element having graphic and functional properties and graphically representing the second contact, an unambiguous identification and contact data being allocated to the contact element; accessing the contact data using a program and setting up a first connection from the first node to the communication system; checking within the communication system using the unambiguous identification whether the contact element is approved by the communication system for the setting-up of connections; and setting up a second connection to the second node depending on a result of the checking.09-04-2008
20080214214Method and System for Telecommunication with the Aid of Virtual Control Representatives - Method and system of telecommunication between at least two users over a telecommunications network, wherein the first user is connected to the telecommunications network via a first terminal and the second user via a second terminal, and wherein a virtual representative is allocated to each user. A first virtual representative is allocated to the first user and a second virtual representative to the second user. The first and second virtual representatives are presented on the first terminal and on the second terminal. Information is transferred from the first user to the second user and vice versa by an animation of at least one of the first and second representatives and by an interaction between the first and second representatives, wherein at least one of the animation and the interaction takes place in response to a drag & drop command of a user, and wherein an animation of the first virtual representative takes place in response to a command of the first user and an animation of the second virtual representative takes place in response to a command of the second user.09-04-2008

Patent applications by Michael Greve, Karlsruhe DE

Paula Greve, Lina Lakes, MN US

Patent application numberDescriptionPublished
20120011252PRIORITIZING NETWORK TRAFFIC - Methods and systems for operation upon one or more data processors for prioritizing transmission among a plurality of data streams based upon a classification associated with the data packets associated with each of the plurality of data streams, respectively. Systems and methods can operate to allocate bandwidth to priority data streams first and recursively allocate remaining bandwidth to lesser priority data streams based upon the priority associated with those respective lesser priority data streams.01-12-2012

Paula Greve, Lino Lakes, MN US

Patent application numberDescriptionPublished
20090119740ADJUSTING FILTER OR CLASSIFICATION CONTROL SETTINGS - Methods and systems for adjusting control settings associated with filtering or classifying communications to a computer or a network. The adjustment of the control settings can include adjustment of policy and/or security settings associated with the computer or network. Ranges associated with the control settings can also be provided in some implementations.05-07-2009
20090122699PRIORITIZING NETWORK TRAFFIC - Methods and systems for operation upon one or more data processors for prioritizing transmission among a plurality of data streams based upon a classification associated with the data packets associated with each of the plurality of data streams, respectively. Systems and methods can operate to allocate bandwidth to priority data streams first and recursively allocate remaining bandwidth to lesser priority data streams based upon the priority associated with those respective lesser priority data streams.05-14-2009
20090254663Prioritizing Network Traffic - Methods and systems for operation upon one or more data processors for prioritizing transmission of communications associated with an entity based upon reputation information associated with the entity.10-08-2009

Patent applications by Paula Greve, Lino Lakes, MN US

Rainer Greve, Bad Segeberg DE

Patent application numberDescriptionPublished
20110245202PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF RHINITIS - The present invention relates to a pharmaceutical composition suitable for the prophylactic and/or curative topical treatment of rhinitis, said composition containing in combination and in each case in pharmaceutically efficacious amounts:10-06-2011

Tanja Maria Greve, Birkerod DK

Patent application numberDescriptionPublished
20110257492METHOD FOR DETERMINING THE STATE OF A SKIN DISORDER USING NEAR INFRARED (NIR) SPECTROSCOPY - The invention relates to a non-invasive method for determining the state of a skin disorder using Near Infrared (NIR) spectroscopy as well as a system and an apparatus therefor.10-20-2011