Grepl

Martin Grepl, Hlusovice CZ

Patent application number	Description	Published
20090275747	METHODS FOR THE PREPARATION OF SALTS OF 2-[2-(4-DIBENZO[B,F][1,4]THIAZEPIN-11-YL-1-PIPERAZINYL)ETHOXYL]ETHANOL (QUETIAPINE) AND FOR THE PURIFICATION THEREOF - A method for the preparation of salts of 2-[2-(4-dibenzo[b,fj[1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol (quetiapine) from the quetiapine base and the respective acid, wherein the salt is precipitated from a mixture of solvents, the mixture being either a mixture of an aromatic hydrocarbon and a ketone or ester, or that of an aromatic hydrocarbon, water and a ketone or ester. The salts of quetiapine are purified by partial crystallization, wherein only a part of the salt of quetiapine is dissolved in a C	11-05-2009
20110034702	METHOD FOR PREPARING 4-[3,5-BIS(2-HYDROXYPHENYL)-[1,2,4]TRIAZOL-1-YL]-BENZOIC ACID - A method for preparing 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid of formula (I) by reaction of 2-(2-hydroxyphenyl)benz[e][1,3]oxazin-4-one of formula (II) with 4-hydrazinobenzoic acid of formula (III) in an organic acid or in a mixture of an organic acid and an organic solvent.	02-10-2011

Patent application number	Description	Published
20110015841	method for ascertaining a wheel reference speed of a wheel on a vehicle having a hydrostatic drive, and device for ascertaining a wheel reference speed of a wheel of a vehicle having a hydrostatic drive - A method for ascertaining a wheel reference speed of a wheel of a vehicle having a hydrostatic drive which uses a transfer medium, the hydrostatic drive acting at least on the one wheel, and the hydrostatic drive having an oscillating motor which may be swiveled to a pumping mode via which a torque may be applied to the wheel, and a wheel speed sensor for detecting the particular wheel speed being situated near the wheel, and the oscillating motor being appropriately adjusted while the wheel speed sensor ascertains the wheel reference speed in order to allow resistance-free flow of the transfer medium through the oscillating motor. The exemplary embodiments and/or exemplary methods of the present invention further relates to a device having arrangements for carrying out the method, and configured as a hydraulic drive control unit, for example.	01-20-2011
20110018338	HYDRAULIC BREAK SYSTEM - The invention relates to a hydraulic brake system (	01-27-2011

Patent application number	Description	Published
20080248535	RAPID ONE-STEP REVERSE TRANSCRIPTASE PCR - The present invention is directed to a method for performing a one-step RT-PCR for amplifying a target RNA comprising the steps (i) providing a sample which is supposed to contain said target RNA (ii) adding a reaction mixture comprising all reagents necessary to reverse transcribe said target RNA into cDNA and amplify at least a portion of said cDNA (iii) incubating said sample for a time interval of 0 seconds to 40 seconds at a temperature between 20° C. and 65° C., and (iv) subjecting said sample to multiple cycles of a thermocycling protocol wherein the temperature of said sample is varied between at least a first temperature between 37° C. and 72° C. and a second temperature between 85° C. and 100° C.	10-09-2008