Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Grenet
Benjamin Grenet, Moye FR
| Patent application number | Description | Published |
|---|---|---|
| 20120011747 | FOOTWEAR WITH IMPROVED SOLE ASSEMBLY - An article of footwear including an outer sole assembly and an upper, the outer sole assembly extending lengthwise from a rear end to a front end, and widthwise between a lateral side and a medial edge, the outer sole assembly having a surface for contact with the ground. The contact surface has a first strip, the first strip having an alternation of projections and recesses. The contact surface has a second strip, the second strip having an alternation of projections and recesses. The projections and recesses of the first strip are arranged alternately with respect to the projections and recesses of the second strip. | 01-19-2012 |
Genevieve Grenet, Lyon FR
| Patent application number | Description | Published |
|---|---|---|
| 20080271835 | Method for Relaxing a Stressed Thin Film - A method relaxing a strained thin film, secured via a first main face of an initial support, the second main face of the thin film being a contact face. The method supplies an intermediate support including a polymer layer having a main free contact face, the polymer's thermal expansion coefficient being greater than that of the thin film, adhesively brings into contact the contact face of the strained thin film with the contact face of the polymer layer, eliminates the initial support, realizing relaxation of the thin film through formation of wrinkles and revealing the first main face of the thin film, increases the polymer layer temperature to stretch the relaxed thin film and eliminate the wrinkles, secures the first main face of the thin film with one face of a receiving substrate, and eliminates the intermediate support to obtain a relaxed thin film integral with the receiving substrate. | 11-06-2008 |
Jean-Michel Grenet, Village Neuf FR
| Patent application number | Description | Published |
|---|---|---|
| 20100216254 | DRUG MONITORING ASSAY - A method for obtaining at least one binding agent which binds a pharmaceutically active form of the compound with a higher specificity than a pharmaceutically inactive form of the compound is described by using special derivatives of said parent compound. The invention also pertains to the respectively created binding agents and derivatives. Furthermore, drug monitoring assays using said binding agents for monitoring pharmaceutically active forms of said parent compound are provided. | 08-26-2010 |
Olivier Grenet, Blotzheim FR
| Patent application number | Description | Published |
|---|---|---|
| 20100221186 | BIOMARKERS FOR CARDIOVASCULAR SIDE-EFFECTS INDUCED BY COX-2 INHIBITORY COMPOUNDS - Cardiovascular tissue mRNA expression profiles in monkeys treated with coxibs was analyzed. Genomic data indicated that the animals showing vasculitis exhibit a specific mRNA expression pattern. The pattern includes gene expression changes involved in blood and endothelial cell (EC) activation, interaction of blood cells with EC, activation of INFγ pathway, and release of pro-inflammatory cytokines and chemo-attractants. These results provide direct evidence of minimal vasculitis together with corresponding genomic signature and peripheral biomarkers for minimal vasculatis. These results also suggest that treatment might triggers/aggravate a clinically latent cardiovascular disorder in the context of an endothelium tropic viral infection and/or an autoimmune vascular disorder. The histopathological examination revealed marginal vascular changes consistent with the genomic findings. Measurement of soluble proteins present in serum and plasma using a multiplex assay were in line with the genomic results, showing the increased level of INFγ inducible proteins, increased expression of CXCL10 chemokine was confirmed by an ELISA both in serum and plasma. Use of these peripheral biomarkers allows a safe usage of cox-2 inhibitory compounds in clinics and selection of cox-2 inhibitory follow-up compounds with no cardiovascular toxicity. These data together with biochemical and histopathological findings suggest that the specific cox2 inhibitor may exaggerate host immune response during some specific viral infections with endothelial tropism, or subjacent vascular autoimmune disorders. | 09-02-2010 |
Olivier Grenet, Michelbach Le Haut FR
| Patent application number | Description | Published |
|---|---|---|
| 20100143956 | PREDICTIVE RENAL SAFETY BIOMARKERS AND BIOMARKER SIGNATURES TO MONITOR KIDNEY FUNCTION - Biomarker signatures were identified which can be used to diagnose or predict kidney or liver toxicity and more specifically renal tubular toxicity as a consequence of disease or drug treatment. | 06-10-2010 |
Pierre Grenet, Grenoble FR
| Patent application number | Description | Published |
|---|---|---|
| 20110153233 | SYSTEM FOR MEASURING A MAGNETIC FILED COMPRISING A THREE-AXIS SENSOR FOR MEASURING A MAGNETIC FILED THAT IS ABLE TO MOVE TOGETHER WITH A CARRIER THAT DISRUPTS THE MEASUREMENTS, AND ASSOCIATED METHOD - The magnetic field measurement system comprises a triaxial main sensor ( | 06-23-2011 |