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| 20080261271 | EXPRESSION OF HIV POLYPEPTIDES AND PRODUCTION OF VIRUS-LIKE PARTICLES - The present invention relates to the efficient expression of HIV polypeptides in a variety of cell types, including, but not limited to, mammalian, insect, and plant cells. Synthetic expression cassettes encoding the HIV Gag-containing polypeptides are described, as are uses of the expression cassettes in applications including DNA immunization, generation of packaging cell lines, and production of Env-, tat- or Gag-containing proteins. The invention provides methods of producing Virus-Like Particles (VLPs), as well as, uses of the VLPs including, but not limited to, vehicles for the presentation of antigens and stimulation of immune response in subjects to whom the VLPs are administered. | 10-23-2008 |
| 20090104226 | Alphavirus Vectors for Respiratory Pathogen Vaccines - Described herein are compositions and methods for stimulating an immune response to one or more proteins derived from one or more respiratory pathogens. In particular, the invention relates to alphavirus replicons, alphavirus vector constructs, alphavirus replicon particles expressing one or more antigens derived from one or more respiratory pathogens as well as to method of making and using these immunogenic compositions. | 04-23-2009 |
| 20100055128 | METHOD FOR THE PURIFICATION OF ALPHAVIRUS REPLICON PARTICLES - Methods of production and purification for viruses and virus-derived vectors, including those related to alphaviruses, are disclosed. in one aspect, methods of purification that subject alphavirus replicon particle preparations to one or more steps of chromatographic purification, such as using an ion exchange resin, are provided. Also disclosed are methods of characterizing alphavirus replicon particles and utilizing these materials for vaccines and gene-based therapeutics. | 03-04-2010 |
| 20110002958 | Alphavirus Vectors for Respiratory Pathogen Vaccines - Described herein are compositions and methods for stimulating an immune response to one or more proteins derived from one or more respiratory pathogens. In particular, the invention relates to alphavirus replicons, alphavirus vector constructs, and alphavirus replicon particles expressing one or more antigens derived from one or more respiratory pathogens, as well as to methods of making and using the immunogenic compositions. | 01-06-2011 |
| 20110065146 | Expression of HIV polypeptides and production of virus-like particles - The present invention relates to the efficient expression of HIV polypeptides in a variety of cell types, including, but not limited to, mammalian, insect, and plant cells. Synthetic expression cassettes encoding the HIV Gag-containing polypeptides are described, as are uses of the expression cassettes in applications including DNA immunization, generation of packaging cell lines, and production of Env-, tat- or Gag-containing proteins. The invention provides methods of producing Virus-Like Particles (VLPs), as well as, uses of the VLPs including, but not limited to, vehicles for the presentation of antigens and stimulation of immune response in subjects to whom the VLPs are administered. | 03-17-2011 |
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| 20110140246 | DELTA-DOPING AT WAFER LEVEL FOR HIGH THROUGHPUT, HIGH YIELD FABRICATION OF SILICON IMAGING ARRAYS - Systems and methods for producing high quantum efficiency silicon devices. A silicon MBE has a preparation chamber that provides for cleaning silicon surfaces using an oxygen plasma to remove impurities and a gaseous (dry) NH | 06-16-2011 |
| 20110169119 | METHODS TO FABRICATE AND IMPROVE STAND-ALONE AND INTEGRATED FILTERS - Embodiments of the invention provide for fabricating a filter, for electromagnetic radiation, in at least three ways, including (1) fabricating integrated thin film filters directly on a detector; (2) fabricating a free standing thin film filter that may be used with a detector; and (3) treating an existing filter to improve the filter's properties. | 07-14-2011 |
| 20110169160 | REAL TIME MONITORING OF INDIUM BUMP REFLOW AND OXIDE REMOVAL ENABLING OPTIMIZATION OF INDIUM BUMP MORPHOLOGY - A method, apparatus, system, and device provide the ability to form one or more solder bumps on one or more materials. The solder bumps are reflowed. During the reflowing, the solder bumps are monitored in real time. The reflow is controlled in real time, thereby controlling a morphology of each of the solder bumps. Further, the wetting of the solder bumps to a surface of the materials is controlled in real time. | 07-14-2011 |
| 20110300716 | METHOD OF IMPROVING FILM NON-UNIFORMITY AND THROUGHPUT - Methods, apparatus, and systems for depositing materials with gaseous precursors are provided. In certain implementations, the methods involve providing a wafer substrate to a chamber of an apparatus. The apparatus includes a showerhead to deliver a gas to the chamber, a volume, and an isolation valve between the volume and the showerhead. A gas is delivered the volume when the isolation valve is closed, pressurizing the volume. The isolation valve is opened to allow the gas to flow to the showerhead when the gas is being delivered to the volume. A material is formed on the wafer substrate using the gas. In some implementations, releasing the pressurized gas from the volume reduces the duration of time to develop a spatially uniform gas flow across the showerhead. | 12-08-2011 |
| 20110316110 | ATOMIC LAYER DEPOSITION OF CHEMICAL PASSIVATION LAYERS AND HIGH PERFORMANCE ANTI-REFLECTION COATINGS ON BACK-ILLUMINATED DETECTORS - A back-illuminated silicon photodetector has a layer of Al | 12-29-2011 |
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| 20090128620 | Demultiplexing for stereoplexed film and video applications - A method for demultiplexing frames of compressed image data is provided. The image data includes a series of left compressed images and a series of right compressed images, the right compressed images and left compressed images compressed using a compression function. The method includes receiving the frames of compressed image data via a medium configured to transmit images in single frame format, and performing an expansion function on frames of compressed image data, the expansion function configured to select pixels from the series of left compressed images and series of right compressed images to produce replacement pixels to form a substantially decompressed set of stereo image pairs. Additionally, a system for receiving stereo pairs, multiplexing the stereo pairs for transmission across a medium including single frame formatting, and demultiplexing received data into altered stereo pairs is provided. | 05-21-2009 |
| 20090184890 | Enhanced zscreen modulator techniques - A method and system for use in conjunction with a push-pull liquid crystal modulator system for creating circularly polarized light of alternating handedness is provided. The method and system comprise a pair of surface mode liquid crystal cells and a driver electrically coupled to the cells. The driver is configured to move an electrical charge using a quenching pulse comprising a relatively brief voltage spike at a beginning of a waveform period. Multiple additional improvements are provided, including reducing the thickness of the LC gap (the distance between cell electrode plates), creating a charge connection or wiring connection to the cell electrodes, employing anti-reflection coating technology, thinner ITO and ITO index matched to the LC material, bonding all possible air to material surfaces, using superior glass, employing more efficient polarizers, and reducing projector blanking time. | 07-23-2009 |
| 20090246404 | Enhanced projection screen - An apparatus and method for producing a screen is provided. The method includes propelling a quantity of paint comprising metallic flakes, such as aluminum flakes, toward the screen. The method also includes applying at least one magnetic field in a vicinity of the screen, wherein applying the at least one magnetic field causes at least one metallic flake in the quantity of paint to be oriented relative to the screen in a substantially preferred orientation, thereby producing a screen exhibiting beneficial projection qualities, such as brightness. The magnetic field(s) applied may be unsymmetric in the time domain of, for example, an AC component of the magnetic field. | 10-01-2009 |
| 20100214396 | Dual ZScreen Projection - A system and method for projecting stereoscopic images using a multiple projector arrangement is provided. The design comprises transmitting a first field train from the first projector, the first field train comprising first projector left and right images and concurrently transmitting a second field train from the second projector, the second field train comprising second projector left and right images. The first projector left image is transmitted by the first projector at substantially a same time as the second projector right image is transmitted by the second projector. Alternately, the design comprises transmitting a first field train from the first projector, the first field train comprising first projector left images alternating with first projector right images, and concurrently transmitting a second field train from the second projector, the second field train comprising second projector left images alternating with second projector right images. A quasi-interlacing technique is also provided. | 08-26-2010 |
| 20100277577 | Enhanced ZScreen modulator techniques - A method and system for use in conjunction with a push-pull liquid crystal modulator system for creating circularly polarized light of alternating handedness is provided. The method and system comprise a pair of surface mode liquid crystal cells and a driver electrically coupled to the cells. The driver is configured to move an electrical charge using a quenching pulse comprising a relatively brief voltage spike at a beginning of a waveform period. Multiple additional improvements are provided, including reducing the thickness of the LC gap (the distance between cell electrode plates), creating a charge connection or wiring connection to the cell electrodes, employing anti-reflection coating technology, thinner ITO and ITO index matched to the LC material, bonding all possible air to material surfaces, using superior glass, employing more efficient polarizers, and reducing projector blanking time. | 11-04-2010 |
| 20110025832 | Ghost-compensation for improved stereoscopic projection - A method and system for reducing ghost images in plano-stereoscopic image transmissions is provided. The method comprises establishing a plurality of expected ghosting profiles associated with a plurality of predetermined regions on a screen, and compensating for leakage in each predetermined region of a projected left and right eye images by removing an amount of ghost images leaking from the projected left eye image into the projected right eye image and vice versa. The system comprises a processor configured to receive the quantity of ghost artifacts and compute ghost compensation quantities for left eye images and right eye images. The processor is further configured to remove an amount of actual image ghost artifacts leaking from a projected left eye image into a projected right eye image and vice versa. The processor is also configured to compute ghost compensation quantities for each of a plurality of zones, each zone corresponding to a region on a screen having an expected ghosting profile associated therewith. | 02-03-2011 |
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| 20090289333 | Annealing a Buffer Layer for Fabricating Electronic Devices on Compliant Substrates - A method of forming a thin-film layered electronic device over a flexible substrate comprises the steps of depositing a buffer layer over the flexible substrate, heating the substrate and buffer layer stack to a temperature at which plastic deformation of the buffer layer takes place, cooling the stack, then forming the thin-film electronic device over the plastically deformed buffer layer without further plastic deformation of the buffer layer. The heating and cooling to cause plastic deformation of the buffer layer is referred to as annealing. The thin-film electronic device is formed by a process according to which all steps are performed at a temperature below that at which further plastic deformation of the buffer layer occurs. In-process strain and runout are reduced, improving device yield on flexible substrates. An optional metal base layer may be formed over the buffer layer prior annealing. | 11-26-2009 |
| 20100281963 | NANOINDENTER TIP FOR UNIAXIAL TENSION AND COMPRESSION TESTING - The invention is an indenter tip that is modified to permit both compression testing and tensile testing on samples having dimensions smaller than approximately 1 μm. The modified indenter tip has both a surface that can be used to apply compressive forces, and tines that can be used to engage a free end of a specimen to be tested in tension. The apparatus used to perform the tests includes elements of a scanning electron microscope that permit visualization of the specimen to be tested and the modified indenter tip, so as to permit appropriate alignment and engagement of the same. The apparatus also includes elements of a microindenter that provide mechanical manipulation of the relative position and orientation of the modified indenter tip and of the specimen to be tested, as well as the necessary controls and instrumentation to perform the test and to collect, record and manipulate data. | 11-11-2010 |
| 20100291385 | FABRICATION OF VERTICALLY ALIGNED METALLIC NANOPILLARS - Solid and hollow cylindrical nanopillars with nanoscale diameters are provided. Also provides is a method of making such nanopillars using electron beam lithography followed by the electroplating. | 11-18-2010 |
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| 20110113314 | Multimedia Communication System And Method - Systems and methods are disclosed for creating, editing, sharing and distributing high-quality, media-rich web-based communications. The communications are created in a layered fashion that integrates user-selected text, colors, background patterns, images, sound, music, video, or other media. The systems and methods are used to generate, edit, broadcast, and track electronic presentations, brochures, advertisements (such as banner advertisements on highly trafficked media websites), announcements, and interactive web pages, without the need for the user to understand complex programming languages. | 05-12-2011 |
