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Greef

Arthur R. Greef, Burien, WA US

Patent application numberDescriptionPublished
20080312999Multiple Goal Throughput Analysis - A method of analyzing production throughput is disclosed. The method may define production constraints, define timing constraints, define resource constraints, add a weight to one or more solution strategies for the production throughput and calculate a production throughput solution to satisfy the constraints and the weighted solution strategies and report the calculated production throughput solution.12-18-2008

Charles Greef, Boulder, CO US

Patent application numberDescriptionPublished
20100286377BIOMOLECULES HAVING MULTIPLE ATTACHMENT MOIETIES FOR BINDING TO A SUBSTRATE SURFACE - Methods of binding biomolecules to a substrate are provided that include contacting the biomolecule with a branched linking moiety to form a branched linking structure. The branched linking structure is then contacted with a binding moiety on the substrate to form a coupled substrate binding structure, thereby binding the biomolecule to the substrate. The biomolecule may contain a Lewis base or a nucleophile to react with a Lewis acid or electrophile in the branched linking moiety. Alternatively, the biomolecule may contain a Lewis acid or electrophile that can react with a Lewis base or nucleophile in the branched linking moiety. Additionally, the biomolecule can be bound to the substrate through a covalent or non-covalent bond.11-11-2010
20110201080BIOMOLECULES HAVING MULTIPLE ATTACHMENT MOIETIES FOR BINDING TO A SUBSTRATE SURFACE - Compounds relating to attachment chemistries for binding biomolecules to a substrate surface are described. These include compounds of the following structure:08-18-2011

Charles Greef, Louisville, CO US

Patent application numberDescriptionPublished
20120071342SYSTEM AND METHOD FOR DETECTING MULTIPLE MOLECULES IN ONE ASSAY - A rapid diagnostic system that delivers a panel of serologic assay results using a small amount of blood, serum, or plasma is described. The system includes a disposable cartridge and a reader instrument, based on planar waveguide imaging technology. The cartridge incorporates a microarray of recombinant antigens and antibody controls in a fluidic channel, providing multiple parallel fluorescence assay results for a single sample.03-22-2012

Charles E. Greef, Dallas, TX US

Patent application numberDescriptionPublished
20090319416METHOD OF STRUCTURING REAL ESTATE ASSETS - An system for and method of divesting real property is presented. The system and method improve upon prior art techniques by including one or more of the following advantages: the gain may be immediately booked, there may be no capitalization requirements as there may be on a financing lease, and the gain may avoid Federal income taxation and capital gains taxation.12-24-2009

Charles H. Greef, Ramona, CA US

Patent application numberDescriptionPublished
20090069198Biomolecular Attachment Sites on Microelectronic Arrays and Methods Thereof - Methods of addressing a biomolecule to a selectively addressable electrode are described. A permeation layer overlying a plurality of selectively addressable electrodes is provided. The permeation layer includes a reactive group that is adapted to bond to a biomolecule and that requires activation through a chemical transformation before bonding to the biomolecule. At least one selectively addressable electrode is biased such that a pH change occurs in an overlying solution of the at least one selectively addressable electrode. The reactive group in a portion of the permeation layer above the at least one selectively addressable electrode is then chemically transformed to an activated reactive group as a result of the pH change. A biomolecule is then bound to the permeation layer overlying the at least one selectively addressable electrode through the activated reactive group.03-12-2009