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Graves

Catherine R.l. Graves, Nottingham GB

Patent application numberDescriptionPublished
20120115749Tumour Markers - A method of determining the immune response of a mammal to circulating tumour marker proteins is described in which a sample of bodily fluid, for example plasma or serum, is contacted with a panel of two or more distinct tumour marker antigen. The presence of complexes between the tumour marker antigens and any autoantibodies to the antigens present in the sample are detected and provide an indication of an immune response to a circulating tumour marker protein. The method is useful for the diagnosis of cancer, particularly for identifying new or recurrent cancer in an otherwise assymptomatic patient.05-10-2012

Catherine Rosamund Louise Graves, Nottingham GB

Patent application numberDescriptionPublished
20110086061Cancer Detection Methods and Reagents - The present invention comprises methods and compositions for detecting cancer in an individual comprising autoantibodies to cancer-associated antigens. Specifically, the present invention comprises methods and compositions for detecting autoantibodies to cancer-associated antigen in a bodily fluid as well as use of said autoantibodies as a means to detect the presence of cancer-associated antigens.04-14-2011

Patent applications by Catherine Rosamund Louise Graves, Nottingham GB

Jamie Robert Graves, Edinburgh GB

Patent application numberDescriptionPublished
20120011153IMPROVEMENTS IN OR RELATING TO DIGITAL FORENSICS - New digital forensic techniques and systems are disclosed. System call information is collected from a device under test (DUT) and converted to a sequence format. Thereafter, sequence alignment methods and tools can be used to investigate and identify patterns of behaviour that are suspicious.01-12-2012

Jason A. Graves, Berkshire GB

Patent application numberDescriptionPublished
20110042419METERED DOSE VALVE - An aerosol metering valve comprising: (a) a valve stem movable between a rest position and a firing position comprising: a body portion comprising a circumferential sealing surface (b) a valve body comprising: a body wall, and an internal chamber defined at least in part by the body wall; and (c) a metering gasket having an inner periphery defining an aperture, being disposed near the most interior end of the internal chamber and being configured to be able to form a transient, substantially fluid-tight face seal against the circumferential sealing surface of the valve stem, where at the rest position of the valve stem, the body portion of the valve stem is located within the internal chamber and as the valve stem is moved from its rest position towards its firing position the circumferential sealing surface of the valve stem contacts the metering gasket to form a face seal thereby closing a metering chamber and thereafter further movement of the valve stem towards its firing position causes the metering gasket to deflect while maintaining the seal with the circumferential sealing surface of the valve stem; and wherein the metering gasket in an unbiased configuration is an annular disc having a substantially planar form and where the valve is constructed and arranged such that the inner periphery of the metering gasket is urged out of said substantially planar form at the rest position of the valve stem, or wherein the metering gasket is pre-biased into a dished-shape.02-24-2011

Martin J. Graves, Cambridgeshire GB

Patent application numberDescriptionPublished
20100046695APPARATUS AND METHOD FOR ACQUIRING SECTIONAL IMAGES - Disclosed is a computer implemented method of interrogating volumetric data, the method including the steps of: defining a reference surface relative to the volumetric data; providing an interrogation window lying in a movable interrogation plane intersecting the reference surface and the interrogation window intersecting the volumetric data, said interrogation plane having a pole lying in it about which pole said interrogation plane is rotatable, wherein movement of the interrogation plane provides a corresponding movement of the interrogation window; for each movement of the interrogation plane, determining the point of intersection of said pole and said reference surface, determining the relative angle of rotation of said interrogation plane about said pole and determining the angle of inclination of said pole to said reference surface; and on the basis of said determinations, providing a sectional image through the volumetric data corresponding to the position of the interrogation window within the volumetric data. Also disclosed is a computer system for implementing the method according to any one of the preceding claims, the system includes a processor for performing the steps of the method and a visual display for displaying said sectional image.02-25-2010

Pierre Graves, Cardiff GB

Patent application numberDescriptionPublished
20110039289FLUOROGENIC PEPTIDES AND THEIR METHOD OF PRODUCTION - A method of making a fluorogenic peptide with an acridone fluorophor is provided, the method comprising the steps of: (a) providing an acridone derivative, said acridone derivative having first and second reactive groups (or precursors thereof), (b) providing a solid phase support provided with reactive species for reacting with the first reactive group of the acridone derivative (c) causing the solid phase support and acridone derivative to react so that the acridone derivative is attached to the solid phase support (d) providing the peptide or reagents for the formation of the peptide, and (e) subsequent to step (c), causing the reaction of the second acridone reactive group with the peptide or one or more of the reagents for the formation of the peptide.02-17-2011

Pierre R. Graves, Cardiff GB

Patent application numberDescriptionPublished
20110189787SPECTROMETER AND METHOD OF OPERATING A SPECTROMETER - A photoluminescence spectrometer (08-04-2011

William Graves, Victoria AU

Patent application numberDescriptionPublished
20100234851 TOOL FOR EXTRACTING A PIN - A tool for extracting a pin from a substrate comprises a first lever arm with a body part having a cavity in which the free end of a pin can be received, and a second lever arm which can pivot relative to the first lever arm. A jaw component is provided within the body part which can be actuated from an unlocked position in which a pin within the jaw component can slide freely past the jaw component, and a locked position in which the pin is gripped by engagement of the jaw component with the side wall of the pin, and a support is provided which can slide relative to the body part, in a direction towards the substrate from which the pin is to be extracted. Initial movement of the first lever arm relative to the second lever arm causes the jaw component to be actuated from its unlocked position to its locked position so that an inserted pin is gripped by the jaw component. Continued movement of the first lever arm relative to the second lever arm causes the support to slide relative to the body part, so that an inserted pin which is gripped by the jaw component is displaced relative to the substrate.09-16-2010