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Graupe
Daniel Graupe, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20110251985 | Detection and Prediction of Physiological Events in People with Sleep Disordered Breathing Using a LAMSTAR Neural Network - Apparatus and methods are disclosed for generating and outputting physiological event results from physiological data related to a patient. Physiological event results include results predicting and/or detecting individual physiological events related to a medical condition of the patient. | 10-13-2011 |
Daniel Graupe, Hightland Park, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20110040349 | Noninvasive electrical stimulation system for standing and walking by paraplegic patients - The present invention is concerned with functional electrical stimulation (FES) of paraplegics having spinal cord injuries (SCI), especially for the purpose of walking, where stimulation is applied to motor neurons below the level of the SCI. Specifically, the invention is concerned with FES in closed-loop where closed loop operation is provided by wireless feedback by EMG signals recorded via noninvasive surface EMG electrodes. No wire connections are required between the EMG electrodes and a signal processor (SP) for providing the feedback signal to the SP. Also, no wire feedback is required to send timing information from the stimulation signal generator to blocking circuits, in cases where such circuits are required to protect the wireless transmitters of the feedback information from being damaged by the stimulation pulses. Wireless operation is facilitated by miniature chips (receivers and transmitters), such as used in the Bluetooth technology. Hence, the paraplegic users are not burdened with any wires that are otherwise needed for closed-loop operation and with the need to connect them between the patient's back, legs, and a pocket-borne control box. Furthermore, closed loop operation frees the patients from the need to manually adjust stimulation levels with progression of muscle fatigue. | 02-17-2011 |
Daniel Graupe, Highland Park, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100094377 | Method and apparatus for closed-loop deep brain stimulation in treating neurological diseases - A system that incorporates teachings of the present disclosure may include, for example, implanted deep brain stimulation electrodes, a stimulation sequence pulse generator, one or more implanted sensors for collecting data associated with one or more electrical signal from the vicinity of the site where stimulation is applied by the stimulation electrodes, and one or more noninvasive surface EMG electrodes to be attached to the patient's skin, say, on certain limbs and which may incorporate a wireless transmitter microchip, and a controller. The controller may incorporate one or more wireless receiver microchips to receive inputs from the sensors. It may also have wire input, if placed under the skin of the skull, for inputs from the implanted sensors. It will incorporate a signal processor to process and coordinate the sensed data from the various sensors and to predict the timing for its output commands. The controller also incorporates a decision element to produce a control output to be sent by wire or wireless to the stimulation sequence generator and which may be an on-off command. The signal processor will also discriminate between tremors and intentional movements in the EMG signals utilizing the EMG spectrum. An electronic switch device may be incorporated to allow the implanted electrodes to switch between serving as stimulation electrodes and voltage sensors, thus eliminating the need to implant any separate sensing electrodes. Alternatively, only noninvasive EMG sensing may be employed for closed-loop control. | 04-15-2010 |
| 20110098780 | APPARATUS FOR MANAGING A NEUROLOGICAL DISORDER - A system that incorporates teachings of the present disclosure may include, for example, a Neuro Sensing and Stimulation Device having a conductive lead for implanting in a brain of a living entity, a sensor coupled to the conductive lead for collecting data associated with one or more electrical signals detected in the conductive lead, a stimulator coupled to the conductive lead to apply one or more electrical signals thereto, and a controller. The controller can be operable to collect data associated with one or more electrical signals detected in the conductive lead, determine a stimulation sequence from the collected data, and direct the stimulator to apply on the conductive lead one or more electrical signals determined from the stimulation sequence. Additional embodiments are disclosed. | 04-28-2011 |
Klaus Graupe, Berlin DE
| Patent application number | Description | Published |
|---|---|---|
| 20100247449 | FOAMABLE COMPOSITION ESSENTIALLY FREE OF PHARMACEUTICALLY ACTIVE INGREDIENTS FOR THE TREATMENT OF HUMAN SKIN - The present invention related to the use of a pharmaceutical composition which is essentially free of pharmaceutically active ingredients for the treatment of human skin, especially in the treatment of rosacea, acne, atopic dermatitis, contact dermatitis, perioral dermatitis, psoriasis or neurodermitis, as well as for prophylactic and/or cosmetic purposes. | 09-30-2010 |
Michael Graupe, Foster City, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100310512 | ANTIVIRAL COMPOUNDS - The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds. | 12-09-2010 |
Micheal Graupe, Pacifica, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090047249 | Modulators of toll-like receptor 7 - The present application includes a compound of Formula I or II: | 02-19-2009 |
Nicholas J. Graupe, White Bear Lake, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20120041605 | FLOW AND SCRUBBING PRESSURE CONTROL SYSTEM AND METHODS FOR SURFACE TREATING APPARATUS - A surface treating apparatus ( | 02-16-2012 |
Nick Graupe, White Bear Lake, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20080201896 | Dual Cleaning Mode Carpet Extractor - A carpet extractor ( | 08-28-2008 |
| 20080276414 | Floor Maintenance Machine Using a Spiral, Tufted, Cylindrical Brush - Leading and trailing cylindrical brushes ( | 11-13-2008 |