Patent application number | Description | Published |
20100099099 | METHOD AND TEST KIT FOR THE RAPID DETECTION OF SPECIFIC NUCLEIC ACID SEQUENCES, ESPECIALLY FOR DETECTING OF MUTATIONS OR SNPs - A method and a test kit for rapid detection of specific nucleic acid sequences, especially for detection of mutations or single nucleotide polymorphisms (SNPs), in which the detection reaction takes place in two steps. The first step involves the target-specific amplification reaction, coupled with the probe-hybridization reaction using fluorescence-labeled allele-specific amplification primers. In the second step, the fluorescence is detected by means of commercial fluorescence readers. Genotyping is carried out from the ratio of the end-point fluorescence of the samples and negative controls. | 04-22-2010 |
20100221718 | METHOD AND RAPID TEST FOR DETECTION OF SPECIFIC NUCLEIC ACID SEQUENCES - A universally usable method for specific detection of target nucleic acid sequences, which method can be performed very rapidly and also simply and furthermore which does not need any expensive instrumental systems. The method is intended to be suitable as a molecular genetic rapid test and to respect the requirements of diagnostic specificity assurance. In this regard it is important that only one specific amplification product be detected and that amplification artifacts can be unambiguously discriminated. A nucleic acid amplification kit suitable for performing this method. | 09-02-2010 |
20110039261 | MOBILE RAPID TEST SYSTEM FOR NUCLEIC ACID ANALYSIS - A mobile rapid test system for nucleic acid analysis. A method comprising the steps of amplification of the nucleic acids by means of rapid-PCR technology, conversion of a double-stranded amplification product into a single-stranded DNA fragment, hybridization with a labeled probe and detection of the nucleic acids on a lateral-flow test strip. A device comprising a reaction cavity which preferably consists of a thin film, inlet and outlet openings for the reaction cavity, one or more heatable sample blocks which are connected to miniaturized cooling bodies and a window for reading off the result. The lateral-flow test strip is a component of the mobile rapid test system. Operation of the instrument system requires no external power source, but only batteries or a rechargeable battery. | 02-17-2011 |
20130115597 | METHOD FOR DETECTING SPECIFIC NUCLEIC ACID SEQUENCES - The present invention relates to a method and test kit for detecting specific nucleic acid sequences, comprising the steps of: 1. matrix-dependent new synthesis of the target nucleic acid; 2. target-specific probe hybridization; and 3. detection of the hybridization event. The invention is characterized in that, in the first step, an oligonucleotide 1, which is marked by a marker 1 and is entirely or partially complementary to the target sequence, acts as a primer in the matrix-dependent new synthesis of the target nucleic acid and, in the second step, an oligonucleotide 2, which is marked by a marker 2 and, owing to its melting temperature being lower than that of the oligonucleotide 1, is not involved in the first step, partially or completely hybridizes with the DNA new synthesis product of oligonucleotide 1.The detection of the hybridization reaction can take place both fluorometrically in the form of a homogeneous assay and, for verification of the result, subsequently immunologically. The detection reaction always takes place in time after the matrix-dependent new synthesis has been carried out. | 05-09-2013 |
20130130257 | MOBILE RAPID TEST SYSTEM FOR NUCLEIC ACID ANALYSIS - A mobile rapid test system for nucleic acid analysis. A method comprising the steps of amplification of the nucleic acids by means of rapid-PCR technology, conversion of a double-stranded amplification product into a single-stranded DNA fragment, hybridization with a labeled probe and detection of the nucleic acids on a lateral-flow test strip. A device comprising a reaction cavity which preferably consists of a thin film, inlet and outlet openings for the reaction cavity, one or more heatable sample blocks which are connected to miniaturized cooling bodies and a window for reading off the result. The lateral-flow test strip is a component of the mobile rapid test system. Operation of the instrument system requires no external power source, but only batteries or a rechargeable battery. | 05-23-2013 |
20130157348 | DEVICE FOR DETECTING NUCLEIC ACIDS - The invention relates to a device that allows a target nucleic acid to be detected in a homogeneous batch using two different detection formats. The device comprises at least two heatable sample blocks and a reaction cartridge which contains a base ( | 06-20-2013 |
20130280695 | METHOD, DEVICE AND TEST KIT FOR MOLECULAR-BIOLOGICAL REACTIONS - The invention relates to a device, method and test kit for carrying out molecular-biological reactions, wherein the different components for the molecular-biological reactions are located on a solid carrier in different, spatially separated compartments prior to the start of the reaction. The carrier is preferably a porous filter disk made of polyethylene. Fields of application are the amplification of nucleic acids, for example PCR or RealTime PCR, the reverse transcription of RNA in DNA enzyme-substrate interactions or antigen-antibody interactions, or protein synthesis. | 10-24-2013 |
20150024386 | METHOD AND RAPID TEST FOR THE DETECTION OF SPECIFIC NUCLEIC ACID SEQUENCES - A universally usable method for specific detection of target nucleic acid sequences, which method can be performed very rapidly and also simply and furthermore which does not need any expensive instrumental systems. The method is intended to be suitable as a molecular genetic rapid test and to respect the requirements of diagnostic specificity assurance. In this regard it is important that only one specific amplification product be detected and that amplification artifacts can be unambiguously discriminated. A nucleic acid amplification kit suitable for performing this method. | 01-22-2015 |
Patent application number | Description | Published |
20080244623 | Method, System and Program Product For Dynamically Integrating Backend Systems Into A J2EE Application Server Environment - A method, system and program product for dynamically integrating Backend System instances into a J2EE application server environment, is introduced. The method comprises deploying a J2C connector suitable for Backend System instances belonging to the same type of Backend Systems (A; B; C) into the J2EE application server environment by using a J2C deployment descriptor which does not contain properties for identifying and connecting to a Backend System instance (A | 10-02-2008 |
20080256241 | System and Method for Automatically Managing It-Resources in a Heterogeneous Environment - The present invention provides a system and method for automatically managing IT-resources in a heterogeneous environment on each level of resource abstraction and resource hierarchy by using the concept of the resource-reference object. The resource-reference object represents the link to a referenced resource on a lower level in the hierarchy and may include a priority value assigned by the respective level of hierarchy as well as all information to build a remote request to that referenced resource which may be a single resource or a resource group. Concurrently each resource-reference object itself is accessible from the higher level of hierarchy as an own resource by additional providing a name and a desired state which can differ from desired state of the referenced resource as well as making it externally visible. Resource-reference objects can be grouped to resource groups on the higher level of hierarchy, wherein those resource groups are addressable as own resource-reference object from the next higher level of hierarchy. | 10-16-2008 |
20080276308 | Single Sign On - A method to securely access systems (I, II) of a distributed computer system by entering passwords is described, wherein some systems are accessible by equal, and some systems are accessible by different passwords, comprising the steps of:
| 11-06-2008 |
20100077410 | METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT FOR IMPLEMENTING A WEB SERVICE INTERFACE - A method for using WebServices as a basis for implementing an application programming interface (API) of a high-level programming language between a service application and a client application is disclosed. Function parameters of an API function call represent a complex object structure (COS). The method includes serializing the COS into serialized payload data, encoding the serialized payload data to form a payload string that does not contain any XML-specific characters, and specifying the parameters of the API call in parts of an input message of a corresponding operation in a WSDL document. The method also includes transporting the payload string within the input message to the service application, decoding the payload string to yield the serialized payload data, and deserializing the serialized payload data to restore the COS representing the parameters of the API call. A system and computer program product for implementing the API on the basis of Web Services are also disclosed. | 03-25-2010 |