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Graichen

Andreas Graichen, Norrkoping SE

Patent application numberDescriptionPublished
20090134136Apparatus and method to machine holes - The present invention relates to an apparatus for machining holes, especially to machine holes in a surface of a coated gas turbine airfoil, which apparatus comprises a laser device for laser drilling and an electrode for electrical discharge machining. Further the invention relates to a method to machine a hole into a coated surface with an apparatus of the incipiently mentioned type. Known methods make use of a machine with separate machine heads for laser drilling and electrical discharge machining. By combining these two devices in one machine head the invention gives the possibility to save time and obtain very accurate results.05-28-2009
20100287754Repair of a stationary rotor seal - A method and an apparatus for mobile repair of a stationary rotor seals of a turbo machine is provided. The method includes the following steps, 3D-scanning of the stationary seal, generation of 3D-model of the stationary seal, removing of the damaged spots of the seal using laser cutting, and generating a new seal at the repair spot by use of a second process head, which generates the seal by laser powder cladding. The apparatus includes a 3D-scanner, a cutting tool, and a first process head and a second process head.11-18-2010

Florian Hans Maximilian Graichen, Glen Iris AU

Patent application numberDescriptionPublished
20110126325RECOMBINANT CELLS AND METHODS FOR HYDROXYLATING FATTY ACIDS - The present invention relates to enzymes which possess hydroxylase activity, in particular 42 hydroxylase activity, that can be used in methods of synthesizing modified fatty acids.05-26-2011

Florian Hans Maximilian Graichen, Victoria AU

Patent application numberDescriptionPublished
20110136988CONDENSATION POLYMERS WITH MODIFIED PROPERTIES - The present invention relates to a method of preparing a polymer composition, the method comprising melt mixing an aliphatic condensation polymer with a cyclic ester of general formula (I) where X is an optionally substituted aliphatic hydrocarbon having 2 or more carbon atoms present in the cycle.06-09-2011

Florian Hans Maximilian Graichen, Richmond AU

Patent application numberDescriptionPublished
20110243884BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES - The invention relates to a biodegradable polymer comprising a plurality of releasable bioactive moieties, the releasable bioactive moieties being pendant from and covalently bonded to the biodegradable polymer backbone, wherein the biodegradable polymer backbone is formed from monomeric units that are each coupled via a biodegradable moiety, and wherein the bioactive moieties are capable of being released at a rate equal to or faster than the rate of biodegradation of the polymer backbone.10-06-2011

Kurt Graichen, Berlin DE

Patent application numberDescriptionPublished
20110160519ROTATIONAL PUMP AND METHODS FOR CONTROLLING ROTATIONAL PUMPS - A rotational pump capable of running at a rotational speed (n) having a system for direct or indirect measurement of pressure difference or flow rate across the pump, wherein a control system is designed to calculate an index of pulsatility (PI) of the pressure difference or flow rate, estimating the gradient of PI with respect to the rotational speed (dPI/dn) and regulating the dPI/dn to a pre-defined set-point or regulating the pump in a way that the dPI/dn is minimal.06-30-2011

Ralph Eberhard Graichen, Singapore SG

Patent application numberDescriptionPublished
20090202498DIRECT DIFFERENTIATION OF CARDIOMYOCYTES FROM HUMAN EMBRYONIC STEM CELLS - The present invention relates to the induction of differentiation in stem cells to cardiomyocytes and factors such as prostaglandin alone or in combination with other factors including essential minerals selected from the group including transferrin and selenium, small molecules selected from the group including a p38 MAPK inhibitor such as SB203580 and protein growth factors of the FGF, IGF and BMP families such as but not limited to IGF1, FGF2, BMP2, BMP4 and BMP6. and insulin that influence the process of differentiation to cardiomyocytes. Media that is appropriate for the induction of differentiation of cardiomyocytes from stem cells is also provided wherein the media contains these factors. The use of cardiomyocytes and cardiac progenitors produced by the directed differentiation in transplantation and screening for cardiac compounds is also provided.08-13-2009

Patent applications by Ralph Eberhard Graichen, Singapore SG