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Graham, CA
Alan Graham, Cupertino, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100215364 | Optical Multiplexer System - The optical multiplexer system comprises an optical multiplexer, an output path and an adjustable beam steering element. The optical multiplexer comprises an input port characterized by an original acceptance range. The output path is disposed relative to the optical multiplexer such that a light beam incident on the input port within the original acceptance range enters the output path. The adjustable beam steering element is located adjacent the input port and is adjustable such that a light beam incident on the beam steering element within an enhanced acceptance range enters the output path as an output beam. The enhanced acceptance range is at least angularly greater than the original acceptance range. | 08-26-2010 |
Alan C. Graham, Cupertino, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090268109 | Digital Projection System - A light modulation assembly and an image projector utilizing a plurality of such light modulation assemblies are disclosed. The light modulation assembly includes an optical element, a pre-polarization filter, an image modulator, and an analyzer polarization filter. The optical element has an input port for receiving a light beam. The optical element directs the light beam onto the pre-polarization filter that removes light having a linear polarization in a first direction. The light leaving the pre-polarization filter illuminates the image modulator. The light leaving the image modulator is filtered by the analyzer polarization filter to remove light having a linear polarization with a predetermined direction relative to the first direction. The light leaving the analyzer polarization filter exits the optical element through an output port. A plurality of such assemblies can be combined with a beam splitting assembly to provide an image projector. | 10-29-2009 |
Anaflor Q. Graham, Saratoga, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090215199 | Caffeine Detection Via Internally-Referenced Two Part Assay - Methods, compositions, and apparatus for detecting the presence of caffeine in a liquid sample are provided. In certain embodiments, an internally referenced competitive assay allows a very precise determination of a threshold value of caffeine for use in semiquantitative types of ligand-receptor assays. By using a detection means that participates in two assays, sensitivity is doubled in the maximum sensitivity range and the range can be adjusted to match the predicted concentration range of an analyte. This format and the materials described herein allow the assay to complete within three minutes. In addition, this format accommodates common attributes of liquid samples for detecting caffeine, such as the inclusion of milk or sugar in a coffee-type beverage. | 08-27-2009 |
Andrew D. Graham, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100044121 | SENSORS, ALGORITHMS AND APPLICATIONS FOR A HIGH DIMENSIONAL TOUCHPAD - A high dimensional touchpad (HDTP) controls a variety of computer windows systems and applications by detecting a user's finger movement in the left-right, forward-backward, roll, pitch, yaw, and downward pressure directions. Measurements obtained from the touchpad of at least two attributes of finger movement at two different time intervals are used to provide a first and a second finger position attribute used to control an application on an electronic device. The finger roll angle is determined by detecting the edge and the peak region of a finger contact area. Also, a visual color displayed in an application operating on an electronic device is controlled by a measured-angle value of a finger in contact with a touchpad. | 02-25-2010 |
Barry D. Graham, Vista, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110031166 | SYSTEMS AND METHODS FOR RECOVERING MATERIALS FROM SOIL - Systems and methods for recovering materials from soil are disclosed. In one embodiment, a system for recovering materials from soil comprises a size separation system, a first magnetic separator, a second magnetic separator, an air classifier/scrubber system, and a non-ferrous metal separator. The system for recovering materials from soil can be configured to separate soil from other recoverable materials, including, for example, rock and gravel aggregates, and/or metals. | 02-10-2011 |
Bruce Graham, West Covina, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090248301 | POSITION ESTIMATION FOR NAVIGATION DEVICES - A method of providing position estimation with a navigation device comprises periodically recording magnetic field strength of an area substantially surrounding a navigation device as a user of the navigation device traverses a select pathway. The method combines the recorded magnetic field strength with measurements from at least a dead reckoning portion of the navigation device to provide position estimates along the select pathway. The method further corrects each of the position estimates from a starting position on the select pathway, where each of the corrected position estimates have an error value below one or more previous position estimates and any intervening positions between each of the one or more previous position estimates and the starting position, with the error value corresponding to an error threshold based on the previous position estimates. | 10-01-2009 |
| 20090295376 | MAGNETIC ODOMETER WITH DIRECTION INDICATOR SYSTEMS AND METHODS - Systems and methods for determining a directional movement of an object such as a wheeled vehicle. The system includes a magnet having a north pole and a south pole mounted to the object, a single magnetic sensor positioned such that the sensor can individually detect each magnetic pole as the object moves, the sensor configured to produce a first characteristic signal when a north pole is detected and a second characteristic signal when a south pole is detected, and a processing device in signal communication with the sensor, the processing device configured to determine a directional movement of the object based on a configuration of a signal doublet that includes the first and second characteristic signals. The methods include sensing the north and south poles as they pass the magnetic sensor and determining a direction based on an order in which the north and south poles are sensed. | 12-03-2009 |
Clayton Graham, Oakland, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110184872 | METHODS AND SYSTEMS FOR PRIORITIZING CALL INITIATION IN A REAL ESTATE MANAGEMENT APPLICATION - A real estate service offers a management application for real estate agents to, for example, coordinate and manage real estate activities related to their clients. In one example, such a real estate application includes an embedded dialer application that includes several functionalities to develop a prioritized call initiation queue. In embodiments, the dialer retrieves and prioritizes all contacts associated with the agent using the dialer application. The dialer may utilize one or more of several mechanisms to prioritize the list of contacts to present the final call initiation queue to the user. The prioritization process takes several factors into account, such as, for example, the current availability of the client, a present geographic location of the client, an “emerging star” client, etc. | 07-28-2011 |
Curt Graham, Mission Viejo, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080264100 | Lng Regasification Configurations and Methods - LNG composition of LNG from a storage tank or other source is modified in a process in which the LNG is pumped to a first pressure and split into two portions. One portion of the pressurized LNG is then reduced in pressure and heavier components are separated from the reduced pressure LNG to thereby form a lean LNG. The lean LNG is then pumped to a higher pressure and combined with the other portion to form a leaner LNG. Preferably, separation is performed using a demethanizer, wherein part of the demethanizer overhead product is condensed to form the lean LNG, while another portion is used for column reflux. In further preferred configurations, ethane recovery is variable and in yet other configurations, propane or ethane can be delivered via a batching pipeline. | 10-30-2008 |
| 20090277219 | Configurations and Methods for Offshore LNG Regasification and BTU Control - LNG is pumped to supercritical pressure and vaporized, preferably in an offshore location to thereby form a natural gas stream with an intermediate temperature. A first portion of that stream is then processed in an onshore location to remove at least some non-methane components to thereby form a lean LNG, which is then combined with a second portion of that stream to form a sales gas having desired chemical composition. The intermediate temperature and the split ratio of the gas stream in first and second portion are a function of the concentration of the non-methane components in the LNG. | 11-12-2009 |
| 20100011810 | NGL Recovery Methods and Configurations - Contemplated plants and methods for NGL recovery from feed gases having a carbon dioxide content equal or greater than about 2% employ temperature control configurations that allow high-level and flexible recovery of ethane and heavier components while avoiding freezing of the carbon dioxide in the process. Where the feed gas has a significant fraction of C3+ components and moderate carbon dioxide content, a single column configuration with an intermediate reflux condenser may be used, while two-column configurations may be used for feed gases with high carbon dioxide content and relatively low C3+ component concentration. | 01-21-2010 |
| 20100043488 | NGL Recovery Methods and Configurations - Contemplated NGL plants include a feed gas bypass circuit through which a portion of the feed gas is provided downstream to a vapor portion of the feed gas to thereby increase turbo expander inlet temperature and demethanizer temperature. Contemplated configurations are especially advantageous for feed gases with relatively high carbon dioxide content as they entirely avoid carbon dioxide freezing in the demethanizer, provide additional power production by the turboexpander, and recover C2+ components to levels of at least 80% while achieving a low carbon dioxide content in the NGL product. | 02-25-2010 |
| 20100135880 | Hydrocarbon Based Sulfur Solvent Systems and Methods - Contemplated configurations and methods for elemental sulfur removal from various gases, and especially well acid gases employ a hydrocarbon solvent that dissolves the sulfur to form a rich solvent and that is then regenerated by hydrotreating. Thus, sulfur is removed from the rich solvent as H2S that may then be processed (e.g., in Claus unit or absorption unit) while the regenerated solvent is routed back to the well and associated production pipes. | 06-03-2010 |
David S. Graham, Mountain View, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100012819 | Optical Power Beaming to Electrically Powered Devices - In one embodiment, a transmitter assembly containing a light source is electrically powered. The light source receives electrical power and converts the electrical power to an optical power beam that is directed through free space to an optical-to-elect power converter for a device. The optical-to-electric power converter converts the optical power beam to electrical form, thus providing electrical power to a device. A safety subsystem assures that the emission beyond the hot zone between the transmitter and receiver do not exceed regulatory levels. | 01-21-2010 |
| 20100194207 | WIRELESS POWER TRANSFER WITH LIGHTING - A device including a wireless power transmitter is connected to a light fixture rather than a standard electrical outlet. Optionally, the device also includes at least one light source or includes at least one socket for a light source. Thus, the device connected to the light fixture can output power from the wireless power transmitter and light from the light source. In one embodiment, a power splitter enables independent control over powering the light and the wireless electricity transmitter. This feature allows, for example, the light to be turned off or on while the wireless electricity transmitter remains on. In some embodiments, the device including the wireless power transmitter has the form of a light bulb or light tube, whereas in other embodiments, the device does not have the form of a light bulb or light tube. | 08-05-2010 |
Elaine Graham, Davis, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110283402 | METHODS AND COMPOSITIONS FOR PRODUCING PLANTS WITH ELEVATED BRIX - The invention provides compositions and methods relating to the separation of elevated Brix from linked but undesirable agronomic traits among progeny with introgressions following a cross between | 11-17-2011 |
Howard P. Graham, Temecula, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100198194 | Telescoping Guide Catheter with Peel-Away Outer Sheath - A guide catheter includes an outer guide having an open lumen and a longitudinal pre-stress line extending between a distal end and a proximal end of the outer guide. The outer guide has a longitudinal stiffness that facilitates transmission of forces and prevention of kinking during steering of the outer guide within cardiac vasculature and structures. An inner guide has an open lumen and is movably displaceable within the open lumen of the outer guide. At least a distal end of the outer guide and inner guide are dimensioned for passage into the patient's coronary sinus. A guide handle is connected to the proximal end of the outer guide and includes a longitudinal pre-stress line separable into at least two sections such that guide handle separation splits the outer guide along the longitudinal pre-stress line at the proximal end of the outer guide. | 08-05-2010 |
Jacob Graham, Fremont, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110313404 | STENT DELIVERY SYSTEM HAVING RETENTION STRUCTURE - A stent delivery system including an elongate shaft of a medical device, a stent selectively coupled to a distal portion of the elongate shaft, and a coupling mechanism for selectively coupling the stent to the elongate shaft by inserting a tab on one of the stent or the elongate shaft into an opening in the other of the stent or the elongate shaft. The tab may be deflected from a first position to a second position to disengage the tab from the opening. | 12-22-2011 |
| 20110319904 | DELIVERY SYSTEM HAVING STENT RETENTION STRUCTURE - A drainage stent delivery system including an elongate shaft of a medial device, a drainage catheter or stent, and an interference fit member for selectively coupling the drainage stent to the elongate shaft. The drainage stent is selectively coupled to a distal portion of the elongate shaft by an interference fit between the interference fit member and the drainage stent such that axial movement of the elongate shaft relative to the drainage stent moves the interference fit member from a first position in which the interference fit member is engaged with the drainage stent and forms an interference fit with the drainage stent to a second position in which the interference fit member is disengaged from the drainage stent. | 12-29-2011 |
James Graham, Santa Paula, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110042250 | GOLF BALL PICKER BASKET AND METHOD - There is disclosed a method and a basket for use with a golf ball range picker having a support frame. The basket may include a pair of inwardly offset handles in the basket side walls for ease of lifting when a series of two or more like baskets are arranged in a closely spaced side by side configuration. A pair of front edges of front side wall sections are each tapered outwardly toward the front to minimize or at least greatly reduce the surface area formed by abutting vertical edges with a like basket, to help guide the golf balls being thrown by the range picker into the baskets, and not deflect them inadvertently away from entering the baskets by otherwise providing thick abutting vertical edges which could block the path of travel of the golf balls. A front flange is disposed substantially along the entire length of the front of the basket for resting securely on a front portion of the support frame, and a rear flange is adapted for resting securely on a back portion of the support frame | 02-24-2011 |
James Leverne Graham, Sun Valley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090078106 | Bass Drum System and Method - A bass drum system and method is provided. The bass drum system is comprised of a bass drum including at least one connector and an anchoring harness. The anchoring harness includes at least one first securing point, an anchoring body, and at least one second securing point. The at least one first securing point is connected to the anchoring body at a predefined distance from the at least one second securing point, also connected to the anchoring body. The at least one first securing point attaches to the at least one connector of the bass drum and the anchoring body contacts a seat structure used by a musician. The at least one second securing point attaches to the at least one connector. | 03-26-2009 |
James R. Graham, Fountain Valley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090057228 | SYSTEM AND METHOD OF FILTERING USING STRATIFIED ACTIVATED CARBON - A stratified bed of activated carbon having regions of functionalized and non-functionalized activated carbon can be utilized to remove contaminants from fluids such as groundwater. The functionalized region has activated carbon particles comprising a cationic or anionic compound that can remove organic or inorganic anionic or cationic compounds from the fluid to be treated. The non-functionalized region comprises powdered or granular activated carbon or adsorbent media downstream of the functionalized region and captures any leaching species or compounds from the functionalized region. | 03-05-2009 |
Janet R. Graham, Morgan Hill, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110112491 | Skin Rejuvenation System and Method - Skin rejuvenation system and method in which a pure plant collagen carrier is saturated with a solution of collagen, allantoin, amino acid, propanediol, glycerin, algae, plant DNA living cells, epidermal growth factor, Vitamin E, hyaluronic acid, rose essential, water, and peptide, and the saturated carrier is applied to the skin to be rejuvenated. | 05-12-2011 |
John S. Graham, Scotts Valley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090274332 | Miniaturized Acoustic Boom Structure For Reducing Microphone Wind Noise and ESD Susceptibility - A miniaturized acoustic boom structure includes a microphone boom housing having a wind screen and a microphone pod configured to hold a microphone. The microphone pod has an outer surface secured to an inner surface of the microphone boom housing, an interior having one or more surfaces configured to form an acoustic seal around at least a portion of the periphery of the microphone, and first and second pod port openings. The first and second pod port openings provide sound wave access to opposing sides of a diaphragm of the microphone, and are shaped and spaced away from the first and second microphone ports of the microphone so that an acoustic path length between the first and second pod port openings is greater than an acoustic path length between the first and second microphone ports. | 11-05-2009 |
Jon E. Graham, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090178103 | SPECIFYING AND ENFORCING AT LEAST ONE RUN-TIME POLICY FOR AT LEAST ONE COMPUTER PROCESS EXECUTING ON A COMPUTER SYSTEM - The present invention provides a method and system of specifying and enforcing at least one run-time policy for at least one computer process executing on a computer system, where the computer system includes a computer operating system. In an exemplary embodiment, the method and system include (1) relating the policy with an executable file of the process, (2) associating the policy with a running instance of the process, and (3) enforcing the policy on the running instance. | 07-09-2009 |
| 20110107430 | UPDATING AN OPERATING SYSTEM OF A COMPUTER SYSTEM - The present invention provides a processor-implemented method and system of updating an operating system of a computer system, where the operating system is subject to a system lockdown that does not allow changes to a list of approved executables of the operating system and that does not allow changes to a base system configuration of the operating system. In an exemplary embodiment, the method and system include, (1) identifying at least one trusted updater process in the operating system and (2) allowing the trusted updater process to make at least one change to the list of approved executables. In an exemplary embodiment, the method and system include, (1) identifying at least one trusted updater process in the operating system and (2) allowing the trusted updater process to make at least one change to the base system configuration. | 05-05-2011 |
J. Stephen Graham, Scotts Valley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100070266 | Performance metrics for telephone-intensive personnel - Systems and methods for generating performance metrics to monitor and/or enhance the performance of telephone-intensive personnel are disclosed. The method generally includes detecting voice activity on a receive and/or a transmit channel in a communications system, outputting voicing decision outputs based on the detecting, storing the voicing decision outputs over a period of time to memory, and generating voice activity performance metrics based on the voicing decision output stored in the memory. The generating may include generating a running average ratio of duration of voice activity on the transmit channel to duration of voice activity on the receive channel (talk-listen ratio) over a certain period of time for one or more agents. The talk-listen ratio may be compared to a target ratio. The system may generally include a voice activity detector (VAD) configured to detect voice activity on a receive and/or transmit channel in a communications system, a memory to store outputs from the VAD, and a voice activity analyzer configured to generate performance metrics based on the VAD outputs stored in the memory. | 03-18-2010 |
Kareem Graham, Mountain View, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090280113 | TARGET FOR REGULATING MULTIPLE SCLEROSIS - Methods are provided for decreasing demyelinating inflammatory disease in a subject by inhibiting the activity of chemokine-like receptor 1 (CMKLR1). Methods are also provided for screening for agents that find use in treating demyelinating inflammatory disease in a subject. | 11-12-2009 |
| 20120064092 | Novel Target for Regulating Multiple Sclerosis - Methods are provided for decreasing demyelinating inflammatory disease in a subject by inhibiting the activity of chemokine-like receptor 1 (CMKLR1). Methods are also provided for screening for agents that find use in treating demyelinating inflammatory disease in a subject. | 03-15-2012 |
Kevin Graham, Thousand Oaks, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090130114 | WISE BINDING AGENTS AND EPITOPES - The present invention relates to binding agents for WISE, and includes for their manufacture and use. | 05-21-2009 |
| 20090191212 | Angiopoietin-2 Specific Binding Agents - Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies. | 07-30-2009 |
| 20090304713 | BINDING AGENTS - Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided. | 12-10-2009 |
| 20110097342 | BINDING AGENTS - Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided. | 04-28-2011 |
| 20110311546 | Angiopoietin-2 specific binding agents - Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies. | 12-22-2011 |
| 20120003237 | WISE BINDING AGENTS AND EPITOPES - The present invention relates to binding agents for WISE, and includes for their manufacture and use. | 01-05-2012 |
Kevin Graham, Santa Rosa, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080311222 | System and method for applying medication to a hoof - A gel that includes a fungicide or an anti-bacterial is contained within a single dosage packet that includes a tapered nozzle end and a body. The fungicide or anti-bacterial gel is applied to the hoof of a horse by opening the packet at the tapered nozzle end and squeezing the body. The gel is then spread over the frog and sole of the hoof with a portion of the packet. The gel is heated so that it spreads to recessed areas of the hoof that can contain the bacterial and fungus infections. | 12-18-2008 |
Kevin P. Graham, Brentwood, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120005654 | REPOSITORY RELATIONSHIP PROGRAMMING - Embodiments of systems, methods and computer program products are described for implementing repository relationship programming. Implementations described herein describe processes for implementing a union of concerns, integrating concerns, assembling concerns and separating concerns. | 01-05-2012 |
Mark J. Graham, Carlsbad, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090318536 | METHODS FOR TREATING HYPERCHOLESTEROLEMIA - Disclosed herein are antisense compounds and methods for decreasing LDL-C in an individual having elevated LDL-C. Additionally disclosed are antisense compounds and methods for treating, preventing, or ameliorating hypercholesterolemia and/or atherosclerosis. Further disclosed are antisense compounds and methods for decreasing coronary heart disease risk. Such methods include administering to an individual in need of treatment an antisense compound targeted to a PCSK9 nucleic acid. The antisense compounds administered include gapmer antisense oligonucleotides. | 12-24-2009 |
| 20100144834 | METHODS FOR TREATING HYPERCHOLESTEROLEMIA - Disclosed herein are antisense compounds and methods for decreasing LDL-C in an individual having elevated LDL-C. Additionally disclosed are antisense compounds and methods for treating hypercholesterolemia, or alternatively for treating or preventing atherosclerosis. Further disclosed are antisense compounds and methods for decreasing coronary heart disease risk. Such methods include administering to an individual in need of treatment an antisense compound targeted to a PCSK9 nucleic acid. The antisense compounds administered include gapmer antisense oligonucleotides. | 06-10-2010 |
| 20120077865 | METHODS FOR TREATING HYPERCHOLESTEROLEMIA - Disclosed herein are antisense compounds and methods for decreasing LDL-C in an individual having elevated LDL-C. Additionally disclosed are antisense compounds and methods for treating, preventing, or ameliorating hypercholesterolemia and/or atherosclerosis. Further disclosed are antisense compounds and methods for decreasing coronary heart disease risk. Such methods include administering to an individual in need of treatment an antisense compound targeted to a PCSK9 nucleic acid. The antisense compounds administered include gapmer antisense oligonucleotides. | 03-29-2012 |
Martin H. Graham, Berkeley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090066435 | Time modulation with cosine function - A method and apparatus is described for a time modulated signal. A cosine function is used as the basis for the signal with time intervals at the maximum and minimum values of the cosine function defining the encoded data. The received waveform is twice differentiated to provide a cosine function from which zero crossings are detected and the time intervals determined. | 03-12-2009 |
| 20090086460 | SHIELD AND METHOD FOR REDUCING STRAY ELECTRIC ENERGY (SEE) GENERATED BY A HIGH EFFICIENCY LIGHT BULB. - A conductive shield for surrounding a high efficiency light bulb such as a spiral fluorescent bulb is described. A conductive curtain having apertures through which light may pass is connected to the threaded grounded base of the bulb. The apertures in the curtain present high impedance to stray electrical energy (SEE) from the bulb thereby reducing SEE. | 04-02-2009 |
Matthew R. Graham, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110235663 | Method and System for Managing Light Source Operation - A laser light source experiencing an EOL condition, which might otherwise cause an unscheduled shutdown, is instead operated in a diminished capacity in one or more predetermined or calculated increments. Operating in such diminished capacity continues until the laser system can undergo appropriate maintenance either during a regularly scheduled shutdown or a newly scheduled shutdown. In the meantime, the diminished capacity of the laser system is accommodated by the utilization tool, as appropriate. | 09-29-2011 |
| 20120019826 | ALIGNMENT OF LIGHT SOURCE FOCUS - An extreme ultraviolet light system includes a steering system that steers and focuses an amplified light beam traveling along a propagation direction to a focal plane near a target location within an extreme ultraviolet light chamber, a detection system including at least one detector positioned to detect an image of a laser beam reflected from at least a portion of a target material within the chamber, a wavefront modification system in the path of the reflected laser beam and between the target location and the detection system, and a controller. The wavefront modification system is configured to modify the wavefront of the reflected laser beam as a function of a target focal plane position along the propagation direction. The controller includes logic for adjusting a location of the focal plane of the amplified light beam relative to the target material based on the detected image of the reflected laser beam. | 01-26-2012 |
Michael D. Graham, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090088659 | Biological Sensing With Haptic Feedback - Systems and methods as described the present disclosure are capable of generating haptic feedback in response to sensing a biological signal from a vertebrate. A method according to one embodiment, among others, includes detecting a neural signal from a vertebrate. The method also includes generating a haptic effect on the vertebrate corresponding to the neural signal. | 04-02-2009 |
| 20090189746 | Actuating A Tactile Sensation In Response To A Sensed Event - Systems and methods for actuating a tactile stimulation in response to detecting a specific event associated with exposure to a particular environmental or physiological condition are described herein. A tactile stimulation device, according to one of several implementations, comprises a sensing layer, an actuating layer, and an adhesive layer. The sensing layer, which is sensitive to exposure to a particular condition, is configured to sense when a specific event associated with exposure to the particular condition occurs. The actuating layer is configured to provide a tactile stimulation to a human subject when the specific event occurs. The adhesive layer is configured to affix the sensing layer and actuating layer with respect to a surface portion of the skin of the human subject such that the human subject can sense the tactile stimulation provided by the actuating layer. The sensing layer, actuating layer, and adhesive layer can be bonded together to form a relatively flat structure. | 07-30-2009 |
| 20110128133 | ACTUATING A TACTILE SENSATION IN RESPONSE TO A SENSED EVENT - Systems and methods for actuating a tactile stimulation in response to detecting a specific event associated with exposure to a particular environmental or physiological condition are described herein. A tactile stimulation device, according to one of several implementations, comprises a sensing layer, an actuating layer, and an adhesive layer. The sensing layer, which is sensitive to exposure to a particular condition, is configured to sense when a specific event associated with exposure to the particular condition occurs. The actuating layer is configured to provide a tactile stimulation to a human subject when the specific event occurs. The adhesive layer is configured to affix the sensing layer and actuating layer with respect to a surface portion of the skin of the human subject such that the human subject can sense the tactile stimulation provided by the actuating layer. The sensing layer, actuating layer, and adhesive layer can be bonded together to form a relatively flat structure. | 06-02-2011 |
Nicholette Rene Graham, Tujunga, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100252564 | PIPING TIP CAP - A cap which frictionally engages a piping tip has a generally conical cover portion with an interior surface, an exterior surface, a closed end and an open end sized to fit over a piping tip; a gripping portion on the exterior surface of the closed end of the cover portion; and a plurality of protuberances on the interior surface of the cover portion extending toward the closed end of the cover portion. The cap can include a circular ridge extending circumferentially around the interior surface of the cap, the ridge sized to fit within a circular indentation in the piping tip to maintain the cap on the piping tip. | 10-07-2010 |
Richard Graham, Irvine, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090131307 | PHARMACEUTICAL COMPOSITIONS COMPRISING CYCLOSPORINS - A composition is described herein comprising cyclosporin A, polysorbate 80, a polyoxyethylene stearate, and an oil; wherein the composition is an emulsion which is ophthalmically acceptable. Methods of treating diseases or conditions using said compositions, and medicaments related thereto, are also disclosed herein. | 05-21-2009 |
| 20110105581 | OPHTHALMIC FORMULATIONS CONTAINING SUBSTITUTED GAMMA LACTAMS AND METHODS FOR USE THEREOF - The invention provides ophthalmic formulations containing well-defined substituted gamma lactams. The formulations described herein are useful in treating a variety of ocular diseases related to ocular hypertension, such as for example, glaucoma. | 05-05-2011 |
Richard S. Graham, Irvine, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080207495 | CYCLOSPORIN COMPOSITIONS FOR OCULAR ROSACEA TREATMENT - Disclosed herein are methods of treating ocular rosacea with cyclosporin A. Compositions and medicaments related thereto are also disclosed. | 08-28-2008 |
| 20090312337 | COMPOSITIONS CONTAINING ALPHA-2-ADRENERGIC AGONIST COMPONENTS - Compositions useful for improving effectiveness of alpha-2-adrenergic agonist components include carrier components, alpha-2-adrenergic agonist components, solubility enhancing components which aid in solubilizing the alpha-2-adrenergic agonist components. In one embodiment, the alpha-2-adrenergic agonist components include alpha-2-adrenergic agonists. In another embodiment, the solubility enhancing components include carboxymethylcellulose. | 12-17-2009 |
| 20090326034 | KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN - The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac. | 12-31-2009 |
| 20100087503 | KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN - The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution which provides increased visual acuity in users and wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient which is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac. | 04-08-2010 |
| 20110021595 | KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN - The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises mixtures of carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye and improve visual acuity of the users. | 01-27-2011 |
| 20110046198 | KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN - The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac. | 02-24-2011 |
| 20110160271 | KETOROLAC TROMETHAMINE COMPOSITIONS FOR TREATING OR PREVENTING OCULAR PAIN - The present invention provides an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose in an aqueous solution wherein said concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac. | 06-30-2011 |
| 20110250294 | COMBINATIONS OF PRESERVATIVE COMPOSITIONS FOR OPHTHALMIC FORMULATIONS - The present invention provides a preservative composition for protecting ophthalmic solutions from microbial attack comprising a combination of benzalkonium ion and An oxy-chlorite moiety, e.g. purite wherein the combined concentrations of benzalkonium ion and An oxy-chlorite moiety, e.g. purite in said composition is sufficient to provide protection against microbial attack when said composition is added to an ophthalmic solution as compared to said ophthalmic solution having the same concentration of benzalkonium ion and An oxy-chlorite moiety, e.g. purite, alone. | 10-13-2011 |
| 20110251285 | COMBINATIONS OF PRESERVATIVES FOR OPHTHALMIC COMPOSITIONS - The present invention provides a preservative composition for protecting ophthalmic solutions from microbial attack comprising a combination of benzalkonium ion and polyhexamethylene biguanide (PHMB) wherein the combined concentrations of benzalkonium ion and polyhexamethylene biguanide (PHMB) in said composition is sufficient to provide protection against microbial attack when said composition is added to an ophtalmic solution as compared to said ophthalmic soulution having the same concentration of benzalkonium ion and polyhexamethylene biguanide (PHMB), alone. | 10-13-2011 |
| 20110275688 | KETOROLAC COMPOSITIONS FOR CORNEAL WOUND HEALING - The present invention is directed to an aqueous ophthalmic solution comprising an effective amount of ketorolac which comprises carboxymethyl cellulose which promotes epithelial wound healing in a patient's cornea. | 11-10-2011 |
Robert Graham, San Francisco, CA US
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|---|---|---|
| 20110159608 | GENETIC POLYMORPHISMS IN AGE-RELATED MACULAR DEGENERATION - The application relates to methods for determining whether a patient is at increased risk of developing wet AMD or whether a patient has an increased likelihood of benefiting from treatment with a high-affinity anti-VEGF antibody. | 06-30-2011 |
Robert R. Graham, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100092977 | IRF-5 HAPLOTYPES IN SYSTEMIC LUPUS ERYTHEMATOSUS - Methods and materials involved in diagnosing SLE are provided herein. The methods and materials can be used to diagnose SLE and/or assess a mammal's susceptibility to develop SLE, based on the presence or absence of one or more IRF-5 variants. | 04-15-2010 |
| 20100099101 | METHODS FOR TREATING, DIAGNOSING, AND MONITORING LUPUS - Methods of identifying, diagnosing, and prognosing lupus, including certain subphenotypes of lupus, are provided, as well as methods of treating lupus, including certain subpopulations of patients. Also provided are methods for identifying effective lupus therapeutic agents and predicting responsiveness to lupus therapeutic agents. | 04-22-2010 |
| 20110046094 | METHODS AND COMPOSITIONS FOR IDENTIFYING AND TREATING LUPUS - A unique set of genetic variations associated with lupus are provided. Also provided are methods for detecting such genetic variations and for assessing risk of developing lupus as well as for diagnosing and treating lupus. | 02-24-2011 |
| 20120003641 | GENETIC POLYMORPHISMS IN AGE-RELATED MACULAR DEGENERATION - Methods for determining whether a patient is at increased risk of developing wet AMD or whether a patient has an increased likelihood of benefiting from treatment with a high-affinity anti-VEGF antibody. | 01-05-2012 |
Robert Royal Graham, So San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120107315 | Predicting progression to advanced age-related macular degeneration using a polygenic score - The present invention relates to methods for identifying individuals with intermediate age-related macular degeneration (AMD) who possess a greater risk of progression to advanced AMD, using a polygenic score calculated based on the results of genome-wide gene association studies, using thousands of single-nucleotide polymorphisms (SNPs). | 05-03-2012 |
Roger W. Graham, Santa Barbara, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120126121 | Processing Detector Array Signals Using Stacked Readout Integrated Circuits - According to certain embodiments, an apparatus comprises a first readout integrated circuit (ROIC), a second ROIC, and a dual band detector array. The first ROIC comprises first unit cells. The second ROIC is disposed outwardly from the first ROIC and comprises a second unit cells. Electrically conductive vias are disposed through the second ROIC and at least into the first ROIC. The detector array is disposed outwardly from the second ROIC. The detector array is configured to detect high dynamic range infrared light and comprises detector pixels. Each detector pixel is configured to generate a current in response to detecting light and send the current to a via. A via is configured to send the signal to a second unit cell and a first unit cell. | 05-24-2012 |
Ron Graham, Carlsbad, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110160082 | Mobility-Modified Nucleobase Polymers and Methods of Using Same - The present invention relates generally to nucleobase polymer functionalizing reagents, to mobility-modified sequence-specific nucleobase polymers, to compositions comprising a plurality of mobility-modified sequence-specific nucleobase polymers, and to the use of such polymers and compositions in a variety of assays, such as, for example, for the detection of a plurality of selected nucleotide sequences within one or more target nucleic acids. The mobility-modifying polymers of the present invention include phosphoramidite reagents which can be joined to other mobility-modifying monomers and to sequence-specific oligonucleobase polymers via uncharged phosphate triester linkages. Addition of the mobility-modifying phosphoramidite reagents of the present invention to oligonucleobase polymers results in unexpectedly large effects the mobility of those modified oligonucleobase polymers, especially upon capillary electrophoresis in non-sieving media. | 06-30-2011 |
Ronald Graham, Carlsbad, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100022001 | Cationic Liposomes And Method of Use - Highly efficient cationic liposomes are provided as a system for the delivery to cells of agents or compounds, such as, compounds capable of silencing a target protein and enzyme substrates. The cationic liposomes can be used in methods of detecting the inhibition activity or apparent activity of a target protein in a cell, and methods of identifying a protein associated with a pathway, such as, a signal transduction pathway in a cell. | 01-28-2010 |
Timothy M. Graham, Santa Rosa, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100244870 | DOPANT PROFILE MEASUREMENT MODULE, METHOD AND APPARATUS - An apparatus comprises: a first signal source; a dopant profile measurement module (DPPM) configured to receive a portion of the signal from the signal source; a probe tip connected to the reflective coupler; a load connected in parallel with the probe tip; and a second signal source connected to a load, wherein the signal source is configured to provide an amplitude-modulated (AM) signal to the probe tip. A method is also described. | 09-30-2010 |