Graeme Cameron Murray Smith

Graeme Cameron Murray Smith, Cambridgeshire GB

Patent application number	Description	Published
20100240645	COMBINATION OF CHECKPONIT KINASE (CHK) AND TELANGIECTASIA MUTATED (ATM) INHIBITORS FOR THE TREATMENT OF CANCER - A combination, comprising a checkpoint kinase (CHK) inhibitor, or a pharmaceutically acceptable salt thereof, and an ataxia telangiectasia mutated (ATM) inhibitor, or a pharmaceutically acceptable salt thereof is described.	09-23-2010
20100249112	COMBINATION OF CHK AND PARP INHIBITORS FOR THE TREATMENT OF CANCERS - A combination, comprising a checkpoint kinase (CHK) inhibitor, or a pharmaceutically acceptable salt thereof, and a poly (ADP-ribose)polymerase (PARP) inhibitor, or a pharmaceutically acceptable salt thereof is described.	09-30-2010

Patent application number	Description	Published
20080242664	DNA-PK INHIBITORS - A compound of formula I:	10-02-2008
20090023727	PHTHALAZINONE DERIVATIVES - A compound of the formula (I):	01-22-2009
20090035394	USE OF DNA-PK INHIBITION TO SENSITISE ATM DEFICIENT CANCERS TO DNA-DAMAGING CANCER THERAPIES - This invention relates to the finding that inhibition of the catalytic subunit of DNA protein kinase (DNA-PKcs) increases the sensitivity of cancer cells that display an ATM deficient phenotype to DNA damaging therapies, such as irradiation or chemotherapy. Methods of treating cancers displaying an ATM deficient phenotype and methods of determining the susceptibility of a patient to such methods are provided.	02-05-2009
20090043091	ATM INHIBITORS - A compound of formula I:	02-12-2009
20090069303	PHTHALAZINONE DERIVATIVES - A compound of the formula (I):	03-12-2009
20090163477	PHTHALAZINONE DERIVATIVES - A compound of formula (I):	06-25-2009
20100130473	COMPOUNDS - Compounds of formula (I): A-B—C and isomers, salts, solvates, chemically protected forms, and prodrugs thereof wherein: B is selected from the group consisting of formula (i) where R	05-27-2010
20110124638	Pyrido-, Pyrazo- and Pyrimido-Pyrimidine Derivatives as mTOR Inhibitors - There is provided a compound of formula I:	05-26-2011

Patent applications by Graeme Cameron Murray Smith, Cambridge GB