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Graeme
Graeme Bilbe, Neuchatel CH
| Patent application number | Description | Published |
|---|---|---|
| 20080306081 | Combinations of Nicotinic Acetylcholine Alpha 7 Receptor Antagonists - Combinations which comprise at least one nicotinic acetylcholine alpha 7 receptor agonist and at least one compound selected from the group consisting of (a) conventional antipsychotics (b) atypical antipsychotics (c) cognition, attention and/or memory enhancers (d) and to use of these combinations in the treatment of psychiatric disorders. | 12-11-2008 |
| 20100035251 | BioMarkers for the Progression of Alzheimer's Disease - The genetic polymorphism LRRK2 (leucine-rich repeat kinase 2)-T1602S is significantly associated with conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD), with the patients with TT genotype being at greater risk to progress to Alzheimer's disease. The LRRK2-T2352 also showed a trend for conversion to Alzheimer's disease, with the patients with CC genotype tending to progress to Alzheimer's disease. Similar to the APOE-E4 allele, in the presence of a BuChE-K variant, LRRK2-T1602S and LRRK2-T2352 showed a greater association with the rate of conversion from mild cognitive impairment to Alzheimer's disease. In another study with placebo-treated Alzheimer's disease patients, LRRK2-T1602S and LRRK2-T2352 showed a same trend of association. The Alzheimer's disease patients with TT genotype of LRRK2-T1602S or CC genotype of LRRK2-T2352 tended to decline faster on cognitive performance over 6 months, especially in the presence of a BuChE-K variant. The association between the two common LRRK2 polymorphisms and Alzheimer's disease progression shows that LRRK2 may play a role in Alzheimer's disease pathogenesis, especially disease progression, and that polymorphisms of LRRK2 can be used as biomrkers of this progression. | 02-11-2010 |
| 20100063029 | USE OF S-10-HYDROXY-10,11-DIHYDRO-CARBAMAZEPINE FOR THE TREATMENT OF ANXIETY AND BIPOLAR DISORDERS - The present invention relates to the use of a racemate of the compound of formula (I) consisting of at least 85% S-enantiomer and not more than 15% R-enantiomer or of pharmaceutically acceptable salts of said racemate or of the S-enantiomer of formula I or of pharmaceutically acceptable salts of said anantiomer for the treatment of anxiety or other psychiatric disorders with underlying anxiety symptomatologies or for the treatment of affective and attention disorders; pharmaceutical compositions for that purpose and packages comprising said pharmaceutical compositions together with instructions for the use of said compositions for the treatment of anxiety or other psychiatric disorders with underlying anxiety symptomatologies or of affective and attention disorders. | 03-11-2010 |
| 20100093672 | USE OF S1P RECEPTOR MODULATOR - Use of an S1P receptor modulator in the treatment or prevention of a disease or condition dependent on brain-derived neurotrophic factor (BDNF) expression. | 04-15-2010 |
| 20100125063 | COMBINATIONS OF NICOTINIC ACETYLCHOLINE ALPHA 7 RECEPTOR AGONISTS - Combinations which comprise at least one nicotinic acetylcholine alpha 7 receptor agonist and at least one compound selected from the group consisting of (a) conventional antipsychotics (b) atypical antipsychotics (c) cognition, attention and/or memory enhancers (d) and to use of these combinations in the treatment of psychiatric disorders. | 05-20-2010 |
| 20110212980 | COMBINATIONS FOR THE TREATMENT OF MIGRAINE - The present invention relates to novel combinations suitable for the treatment of migraine of various genesis or aetiology, which comprise, as active ingredients, at least one 5-HT | 09-01-2011 |
| 20120245129 | USE OF S1P RECEPTOR MODULATOR - Use of an S1P receptor modulator in the treatment or prevention of a disease or condirion dependent on brain-derived neurotrophic factor (BDNF) expression. | 09-27-2012 |
Graeme Crothall, Gladwyne, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110284026 | PATIENT ROOM CLEANING SYSTEM AND METHOD - A method improving air quality and reducing healthcare-associated infections performed by a cleaning personnel includes the steps of equipping a cleaning cart with a plurality of single-use microfiber cloths and a plurality of microfiber mops, wherein the cleaning cart includes a vacuum cleaning apparatus with an extensible vacuum hose and a plurality of attachments, positioning the cleaning cart outside of an occupied patient room, vacuuming the patient room with the vacuum hose including first and second attachments, disinfecting the surfaces that a patient may contact with a first microfiber cloth soaked in a disinfectant solution, cleaning at least one bathroom fixture with a second microfiber cloth soaked in the disinfectant solution, mopping the floor area including the floor area of the patient restroom with a microfiber mop charged with a neutral cleaner, and placing the microfiber mop in a plastic bag. | 11-24-2011 |
| 20120317747 | NOVEL VACUUM CARTS FOR HOSPITAL CLEANING - A mobile vacuum cart system for use in hospital environments is described. The cart is capable of meeting requirements of ULPA certification, thereby improving air quality and reducing the risk of healthcare-associated infections. | 12-20-2012 |
Graeme Elliner, Brackley Northants GB
| Patent application number | Description | Published |
|---|---|---|
| 20100294746 | LASER SCRIBING PLATFORM WITH MOVING GANTRY - Laser scribing can be performed on a workpiece such as a substrate with layers formed thereon for use in a solar cell without need to move the workpiece during the scribing process. A series of lasers can be used to concurrently remove material from multiple positions on the workpiece. These laser outputs are directed to the workpiece using an optical system partially attached to a gantry. The gantry can be moved longitudinally and the portion of the optical system attached to the gantry can be moved laterally so that the combined outputs of all lasers can be directed to substantially any position on the workpiece without moving the workpiece. | 11-25-2010 |
Graeme Foubister, Aberdeen GB
| Patent application number | Description | Published |
|---|---|---|
| 20120175108 | TEST PACKER AND METHOD FOR USE - A downhole tool having a throughbore is disclosed for use in a tubular located in a wellbore. The downhole tool has a sealing element configured to seal an annulus between the downhole tool and an inner wall of the tubular; at least one flow path formed in the downhole tool, wherein the flow path is configured to allow fluids in the annulus to flow past the sealing element when the sealing element is in a sealed position; and at least one valve in fluid communication with the flow path and configured to allow the fluids to flow through the flow path in a first direction while preventing the fluids from flowing through the flow path in a second direction. A guard may be installed proximate anchor elements. The guard extends radially beyond an outer diameter of the anchor elements when the anchor elements are in a retracted position. | 07-12-2012 |
Graeme Freemantle, Victoria AU
| Patent application number | Description | Published |
|---|---|---|
| 20120114829 | FEED BLOCK COMPOSITION - The present invention relates to an animal feed composition including: (a) 30-98 wt % of vegetable matter; (b) 1-60 wt % of a carbohydrate source; and (c) 1-20 wt % of an inorganic binding agent. | 05-10-2012 |
Graeme Gordon, Helsinki FI
| Patent application number | Description | Published |
|---|---|---|
| 20110134533 | Optical light diffuser component and a method for manufacturing the same - An optical light diffuser component and a method of producing the same. The component comprises at least one substrate material with an index of refraction of n | 06-09-2011 |
Graeme Jones, Whalley Range GB
| Patent application number | Description | Published |
|---|---|---|
| 20120000769 | ELECTRODE STRUCTURE FOR PROTECTION OF STRUCTURAL BODIES - Electrolytic protection of steel-reinforced concrete bodies such as bridges and building facades is achieved with carbon material inserted into the concrete body. The carbon material is connected to act as a anode with the steel reinforcement as a cathode, so that corrosive chloride ions migrate away from the steel reinforcement. The carbon material is inserted so as also to act as a reinforcement. In one arrangement carbon textile material is provided between inner and outer grout-filled plastics ducts fixed around post-tensioned steel cables. In another arrangement a carbon rod, or pin, is fixed between a concrete body and a steel I-beam. | 01-05-2012 |
Graeme Kelbie, Cypress, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110036574 | Spoolable coiled tubing spear for use in wellbores - Coiled tubing spears for retrieving a section of cut coiled tubing comprises a mandrel having attachment members, e.g., spears, at upper and lower ends for facilitating connection of the upper end of the mandrel to a spooled section of coiled tubing and the lower end of the mandrel to a section of cut coiled tubing disposed in a wellbore. Coiled tubing spears comprise one or more centralizers that are releasably secured to the mandrel. The centralizer(s) facilitate lining up a lower attachment member, or spear, with the bore of the section of cut coiled tubing so that the mandrel can be secured to the cut coiled tubing for retrieval. During retrieval of the cut coiled tubing, the centralizer(s) are released from the mandrel so that the mandrel and attachment members can continue through an injector head. | 02-17-2011 |
Graeme Kettlewell, Yorkshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090018575 | TISSUE-ADHESIVE FORMULATIONS - A tissue-adhesive formulation comprises a particulate material having tissue-reactive functional groups, in admixture with a particulate buffer material. The formulation is preferably free or substantially free of materials of human or animal origin. In preferred embodiments, the formulation consists, or consists essentially of, an anhydrous or partially hydrated blend of particulate material having tissue-reactive functional groups and particulate buffer material. Also disclosed is a multilayer sheet comprising a structural support coated on at least one side thereof with such a tissue-adhesive formulation. | 01-15-2009 |
| 20090044895 | TISSUE-ADHESIVE MATERIALS - A multi-lamellar tissue-adhesive sheet comprises a structural layer or laminate conjoined to a tissue-contacting layer. The structural layer or laminate comprises one or more synthetic polymers having film-forming properties, and the tissue-contacting layer of material contains tissue-reactive groups. The synthetic polymers having film-forming properties are preferably biodegradable polyesters, and the tissue-reactive groups are most preferably NHS-ester groups. | 02-19-2009 |
Graeme Langlands, Soham GB
| Patent application number | Description | Published |
|---|---|---|
| 20100063113 | NOVEL PHARMACEUTICAL SALTS AND POLYMORPHS OF A FACTOR XA INHIBITOR - The present invention provides for salts comprising a compound of Formula I and an acid that has activity against mammalian factor Xa. The present invention is also directed to methods of making the compound of Formula I. | 03-11-2010 |
| 20130064806 | NOVEL PHARMACEUTICAL SALTS AND POLYMORPHS OF A FACTOR XA INHIBITOR - The present invention provides for salts comprising a compound of Formula I and an acid that has activity against mammalian factor Xa. The present invention is also directed to methods of making the compound of Formula I. | 03-14-2013 |
Graeme Leithead, Sileby GB
| Patent application number | Description | Published |
|---|---|---|
| 20110182715 | ADJUSTING DEVICE FOR VARIABLE GUIDE VANES AND METHOD OF OPERATION - A device, system, or method to position variable guide vanes disproportionately is provided. An adjusting device for guide vanes of an axial-flow machine, includes a plurality of rotatably mounted rings of variable guide vanes, a plurality of levers which are arranged on the outer sides of a guide vane carrier for rotating the variable guide vanes, a plurality of adjusting rings, each of the adjustment rings is arranged coaxially to the guide vane carrier and to which a first end of one of the levers is connected, and an adjusting drive with which the adjusting rings may be moved in the peripheral direction. At least one of the levers is set up to perform at least partly a disproportionate longitudinal movement of the first end of the at least one lever. | 07-28-2011 |
Graeme Maisey US
| Patent application number | Description | Published |
|---|---|---|
| 20110118645 | Wound Dressing Applicator - A wound dressing applicator ( | 05-19-2011 |
Graeme Mckerrell, Hemel Hempstead GB
| Patent application number | Description | Published |
|---|---|---|
| 20130080775 | SECURING EMAIL CONVERSATIONS - At least a portion of a transmission of an outgoing first email from a first email account to at least a second email account is encrypted. Second email address data is changed corresponding to the second email account to cause replies to the first email intended for the second email account to be sent to an intermediate device prior to being routed to the second email account. Replies to the first email are then sent to the intermediate device and sent over one or more encrypted channels. Replies to the first email including the changed email address data are decoded to identify the second email address data associated with the second email account. A reply to the first email is then sent to the second email account based on the identified second email address data. | 03-28-2013 |
Graeme Milicich, Hamilton NZ
| Patent application number | Description | Published |
|---|---|---|
| 20090324662 | Dental appliance, oral care product and method of preventing dental disease - A method for reducing dental disease in a patient comprises a patient wearing in the patient's mouth an appliance containing an oral care product comprising a carrier and an anti-dental disease agent with a pH above 7.0. The appliance brings the patient's teeth in direct and sustained contact with the product and is custom made for each individual patient. The oral care product is specifically prescribed and formulated for the particular dental disease of that individual patient. | 12-31-2009 |
Graeme Naismith, New South Wales AU
| Patent application number | Description | Published |
|---|---|---|
| 20080315452 | Unit and Method for Molding Opening Devices for Application to Packages of Pourable Food Products - A molding unit for producing an opening device, wherein a web having plural holes is fed to the unit, and the opening device has a spout closed by a membrane, a neck portion projecting from the spout, and a pull ring extending from the membrane inside the neck portion. The unit includes first and second mold devices cooperating with the web to define a closed cavity, and movable to be detached from the web. The unit also has a first and a second matrix which can be set to a configuration in which they are located inside the cavity to define a first and second volume. The matrices are movable relative to the web to disengage the opening device from the volumes and permit removal of the opening device by feeding forward the web. A single actuator moves one of the mold device and the matrices to/from the web. | 12-25-2008 |
Graeme Norval, Oakville CA
| Patent application number | Description | Published |
|---|---|---|
| 20110027165 | Distributed pre-enrichment method and apparatus for production of heavy water - The present invention provides a process whereby pre-enrichment of water streams using a hydrogen source and a catalytic isotope exchange method at one or more remote sites to supply water with augmented deuterium concentration to a central heavy water. This central heavy water plant could be a Combined Electrolysis and Catalytic Exchange (“CECE”) heavy water production plant or a Girdler Sulfide heavy water plant. The deuterium content of water at the remote sites is increased and provides water stream(s) with augmented deuterium concentration to feed to the central heavy water production plant. This could be a first stage of the central CECE deuterium enrichment plant, increasing its capacity for heavy water production approximately in the ratio of its enrichment above natural deuterium concentrations. By relatively simple utilization of available deuterium enrichment capacity at the remote sites, advantages are achieved from a larger scale of heavy water production at the central production plant. The invention further provides systems and methods for adapting chlorate and chlorine dioxide systems which produce hydrogen to additionally produce deuterium-enriched water. | 02-03-2011 |
| 20110027166 | Chlorate and chlorine dioxide systems adapted for the production of deuterium enriched water - The present invention provides a process whereby pre-enrichment of water streams using a hydrogen source and a catalytic isotope exchange method at one or more remote sites to supply water with augmented deuterium concentration to a central heavy water. This central heavy water plant could be a Combined Electrolysis and Catalytic Exchange (“CECE”) heavy water production plant or a Girdler Sulfide heavy water plant. The deuterium content of water at the remote sites is increased and provides water stream(s) with augmented deuterium concentration to feed to the central heavy water production plant. This could be a first stage of the central CECE deuterium enrichment plant, increasing its capacity for heavy water production approximately in the ratio of its enrichment above natural deuterium concentrations. By relatively simple utilization of available deuterium enrichment capacity at the remote sites, advantages are achieved from a larger scale of heavy water production at the central production plant. The invention further provides systems and methods for adapting chlorate and chlorine dioxide systems which produce hydrogen to additionally produce deuterium-enriched water. | 02-03-2011 |
Graeme O'May, Cockeysville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110177111 | PROTECTIVE VACCINE AGAINST STAPHYLOCOCCUS AUREUS BIOFILMS COMPRISING CELL WALL-ASSOCIATED IMMUNOGENS - Vaccine formulations effective against | 07-21-2011 |
Graeme Pendock, Carlisle, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120224846 | Fault Localization and Fiber Security in Optical Transponders - Designs, methods, and applications for fault localization and fiber security in optical transponders is described. In one embodiment a two-way time transfer protocol or other suitable method for synchronizing clocks between distant transponders is used. The clock synchronized transponders have digital signal processing to continually detect high precision time-histories of physical layer attributes in the transmission between the two transponders. Physical layer attributes can include: state-of-polarization changes, changes in polarization-mode-dispersion, change in propagation delay, changes or loss-of-light, changes in OSNR, changes in BER between the two nodes. By recording these physical layer changes and time-stamping them information on the magnitude and estimated location of the changes can be inferred by from the time records. In one aspect the method may be used in a distributed optical sensor for monitoring trespassing events that are a risk to fiber security of an optical transmission link. | 09-06-2012 |
| 20120230676 | TURN-UP AND LONG TERM OPERATION OF ADAPTIVE EQUALIZER IN OPTICAL TRANSMISSION SYSTEMS - In an optical transmission system which utilizes polarization multiplexing, a receiver includes an adaptive equalizer which is adjusted at turn-up such that two polarization modes at the equalizer output are time aligned. The adaptive equalizer may be reset in a directed manner in response to an indication that one polarization mode is present at both the first and second outputs. Further, the dominant filters taps of the adaptive equalizer are maintained near a middle of a tap index range. The receiver may also include an interpolation function upstream of the adaptive equalizer and a symbol timing error estimation function that feeds a control signal back to the interpolation function, wherein the interpolation function causes the adaptive equalizer function and symbol timing error estimation function to receive an integer number of samples per symbol. | 09-13-2012 |
Graeme Taylor, Wolverhampton GB
| Patent application number | Description | Published |
|---|---|---|
| 20110287690 | TOY SNAKE - A toy snake that reproduces the natural movement of a snake as it moves across surface is described. The toy snake comprises a head that is pivotally mounted to a tail and a motor unit located within the head. In a preferred embodiment a body is employed to pivotally mount the head to the tail. The motor unit comprises at least two independently driven wheels located towards opposite sides of the head and the motor unit is configured to introduce a periodic oscillation between the operation of the independently driven wheels. The motor unit may also be configured to operate a tongue that extends out from the head to further increase the realistic nature of the toy. Embodiments of the snake may be adapted for use on land or water. | 11-24-2011 |
Graeme Taylor, Newcastle Upon Tyne GB
| Patent application number | Description | Published |
|---|---|---|
| 20100285712 | METHOD FOR TREATING FABRICS - An emulsion for treating natural fabrics is provided which comprises lanolin, water, perfume and is essentially free of cationic surfactant. Also included is an article for treating natural fabrics wherein the article comprises a substrate and an emulsion, a kit for treating natural fabrics, and a method of treating natural fabrics in a dryer. | 11-11-2010 |
Graeme Wagoner-Lynch, Portland, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20110042538 | CORNER PROTECTOR - A corner protector comprising a guard, strap, and plate or rod are disclosed. The second portion and third portion of the guard are substantially orthogonal to the first portion, and to each other. The second portion and third portion meet to define a corner protrusion. The guard has interior extending ribs that are substantially vertical and maintain contact with the guard. The strap has at least one connection member on each end to allow the corner protector to be adjusted vertically. The plate or rod has at least one locking member for creating a locking mechanism with the connection member. | 02-24-2011 |
| 20120235004 | CORNER PROTECTOR - A corner protector comprising a guard, strap, and plate or rod are disclosed. The second portion and third portion of the guard are substantially orthogonal to the first portion, and to each other. The second portion and third portion meet to define a corner protrusion. The guard has interior extending ribs that are substantially vertical and maintain contact with the guard. The strap has at least one connection member on each end to allow the corner protector to be adjusted vertically. The plate or rod has at least one locking member for creating a locking mechanism with the connection member. | 09-20-2012 |
| 20120311865 | MINERAL BLADE AND RAZOR FOR USE WITH SAME - Disclosed is a razor blade having a mineral blade with a mineral cutting edge, with the mineral cutting edge having a radius of less than about 20 nanometers and an angle of about 40-50 degrees and wherein the mineral blade is coated in an adhesion promoter and an outer layer and a method of making the razor blade. Also disclosed is a razor having a mineral blade, and a method of making the razor. | 12-13-2012 |
Graeme Waitzkin, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080240855 | VEHICLE BARRIER SYSTEM - A security barrier system for use with a trafficable surface and a site requiring protection from advancing vehicles includes a composite bed system having a plurality of elevations and comprising a first layer beneath a second layer. The first layer includes a deformable material configured to collapse when subjected to vehicle loads, and the second layer includes a pedestrian cover surface over the deformable material that conceals the deformable material. The pedestrian cover surface is configured to support pedestrian traffic over the deformable material without permanently collapsing the deformable material and to collapse along with the first layer when subjected to vehicle loads. A structure beyond the bed system is provided to resist the impact of a vehicle that has traversed the bed system. | 10-02-2008 |
| 20080248899 | Lacrosse training tool - A training tool for use by lacrosse players attaches a player's hand or glove to the lacrosse stick. Lacrosse players typically have a dominant hand orientation which they play with, and the development skills in the non-dominant hand orientation is of particular interest. This tool will attach the player's glove to the player's stick in their non-dominant hand orientation, allowing their gloves to slide up and down on the stick, but preventing the player from switching the player's hand orientation, in order to force the use of a non-preferred stick orientation which will strengthen the overall level of a player's skill set. | 10-09-2008 |