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Gradl

Georg Gradl, Rostock DE

Patent application numberDescriptionPublished
20110027381TREATMENT OF OSTEOPOROSIS - The present invention relates to a combination for the treatment of osteoporosis and/or the prophylaxis and treatment of bone fractures, said combination comprising collagen, an additional peptide, a calcium-containing substance and a wetting agent with a terminally functionalized oligolactone. The invention also relates to artificial bones and implants produced by the combination and to the use of said combination for fixing implants and treating osteoporosis and/or the prophylaxis and treatment of bone fractures. The invention further relates to a method for producing artificial bones and implants.02-03-2011

Georg Gradl, Borgerende Rostock DE

Patent application numberDescriptionPublished
20100331993MAGNETICALLY MOUNTED ARTIFICIAL JOINT - The invention relates to a prosthesis for replacing a joint connection, wherein like magnetic fields from the condyle 12-30-2010

Georg Gradl, Borgerende DE

Patent application numberDescriptionPublished
20110238122IMPLANT AND BONE SCREW HAVING INTERLOCKING CAMS - The invention relates to a fixation device for bones, consisting of all implant (09-29-2011

Georg Gradl, Boergerende DE

Patent application numberDescriptionPublished
20120116401REPOSITIONING DEVICE FOR THE HANDLING OF DISTAL RADIUS FRACTURES BY MEANS OF A T-SHAPED OSTEOSYNTHESIS PLATE - The invention relates to a repositioning device for the handling of distal radius fractures by means of a T-shaped osteosynthesis plate, comprising a long leg and a short leg, disposed in a T-shaped and angular manner in relation to said long leg, wherein the short, distal leg has a face that comes into contact with the distal fracture fragment and a number of openings for bone screws and the long, proximal leg is intended for making contact with the proximal bone near the body. To improve the repositioning device in such a way that the required tilting of the articulated face in the palmar direction of the osteosynthesis plate used can be carried out in an angularly faithful manner, the lower face (05-10-2012

Hans-Georg Gradl, Börgerende DE

Patent application numberDescriptionPublished
20090216283BLOCKING DEVICE FOR A BROKEN OR CRACKED BONE - Locking mechanism for a broken or fractured bone, comprising a medulla nail with a proximal portion which may incorporate perforations and a distal portion, and at least one locking aid, characterised in that the distal portion has a surface structure which is designed so that the bone can be stabilised by means of the medulla nail due to the at least one locking aid acting on the surface structure of the nail through the bone from outside, preferably preventing it from rotating and/or being subjected to axial stress.08-27-2009

Hans-Georg Gradl, Börgerende DE

Patent application numberDescriptionPublished
20090216283BLOCKING DEVICE FOR A BROKEN OR CRACKED BONE - Locking mechanism for a broken or fractured bone, comprising a medulla nail with a proximal portion which may incorporate perforations and a distal portion, and at least one locking aid, characterised in that the distal portion has a surface structure which is designed so that the bone can be stabilised by means of the medulla nail due to the at least one locking aid acting on the surface structure of the nail through the bone from outside, preferably preventing it from rotating and/or being subjected to axial stress.08-27-2009

Manfred Gradl, Oberdrauburg AT

Patent application numberDescriptionPublished
20090120122Water supply for supplyingan ice cube maker and/or a water dispenser of a refrigerator and/or freezer - The present invention relates to a water supply device for the water supply of an ice cube maker and/or water dispenser of a refrigerator and/or freezer, comprising a water tank, which includes a filling hole for manually filling the water tank and an outlet connection for connecting the water tank to a supply conduit of the ice cube maker and/or water dispenser. The invention furthermore relates to a refrigerator and/or freezer with such a water supply device. The invention is based on the idea to combine the advantages of a fixed water connection with the advantages of a manually fillable water tank. In accordance with the invention, it is proposed to use a manually fillable water tank on which a fixed water connection is provided for connection of the water tank to a stationary water conduit. The water supply device thereby can selectively be operated manually, in particular when no fixed water connection is provided, or automatically, when such fixed water connection is provided. In this way, the comfort of a fixed water connection is incorporated, but the presence of a stationary water conduit is no condition for mounting or operating the refrigerator with water supply point. In automatic operation, the combination of the manually fillable water tank with the fixed water connection also provides advantages over pure solutions with fixed water connection. Thus, a simple cleaning of the system can be achieved by adding a cleaning agent through the filling hole of the water tank. Other additives also can easily be added to the water to be dispensed. Moreover, when switching over to automatic operation, the first tank fill-up, in particular the water present in the supply conduit for an extended period, can be disposed of in a fast and uncomplicated way by draining the tank.05-14-2009

Manfred Gradl, Oberdrauburg DE

Patent application numberDescriptionPublished
20100095692REFRIGERATOR AND/OR FREEZER - This invention relates to a refrigerator and/or freezer with an ice maker, wherein the appliance includes at least one fan associated to the ice maker, which is arranged such that cold air is supplied to the ice maker by means of the fan.04-22-2010

Stefan Gradl, Princeton, NJ US

Patent application numberDescriptionPublished
20110201593TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF - The invention provides novel compounds of formula I having the general formula:08-18-2011

Stefan N. Gradl, San Diego, CA US

Patent application numberDescriptionPublished
20080261921FUSED RING HETEROCYCLE KINASE MODULATORS - The present invention provides fused ring heterocycles as kinase modulators, pharmaceutical compositions containing these modulators, and methods of using these modulators to treat diseases mediated by kinase activity.10-23-2008
20090005356SUBSTITUTED PYRROLOPYRIDINES AND PYRAZOLOPYRIDINES AS KINASE MODULATORS - Provided herein are substituted pyrrolopyridine heterocycles and substituted pyrazolopyridine heterocycles, pharmaceutical compositions comprising said heterocycles and methods of using said heterocycles in the treatment of disease. The heterocycles disclosed herein function as kinase modulators and have utility in the treatment of diseases such as cancer, allergy, asthma, inflammation, obstructive airway disease, autoimmune diseases, metabolic disease, infection, CNS disease, brain tumor, obesity, asthma, hematological disorder, degenerative neural disease, cardiovascular disease, or disease associated with angiogenesis, neovascularization, or vasculogenesis.01-01-2009
20090143352PYRROLO-PYRIDINE KINASE MODULATIORS - The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.06-04-2009
20100036118Fused Ring Heterocycle Kinase Modulators - The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.02-11-2010
20100305128Pyrimidinyl-Thiophene Kinase Modulators - The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.12-02-2010

Patent applications by Stefan N. Gradl, San Diego, CA US