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Gracias
Alison Gracias, Albany, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100119711 | POLYMERIC MICRO-CANTILEVERS FOR ULTRA-LOW VOLUME FLUID AND LIVING CELL DEPOSITION - Polymer-based micro-cantilevers for depositing material onto a surface include, in one embodiment, a body portion, an elongated beam portion sized smaller than and extending from the body portion and having a length greater than about 500 microns. The body portion includes a reservoir and the elongated beam portion having a passageway disposed therein. The passageway has an inlet opening in fluid communication with the reservoir and an outlet opening at a distal end of the elongated beam portion. The passageway comprises a width greater than 10 microns to about 100 microns, and a height of about 25 microns to about 100 microns. Methods for delivering fluid and living cells using the polymer-based micro-cantilevers are also disclosed. | 05-13-2010 |
David H. Gracias, Baltimore, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090311190 | SELF-ASSEMBLED, MICROPATTERNED, AND RADIO FREQUENCY (RF) SHIELDED BIOCONTAINERS AND THEIR USES FOR REMOTE SPATIALLY CONTROLLED CHEMICAL DELIVERY - The present invention relates to a nanoscale or microscale particle for encapsulation and delivery of materials or substances, including, but not limited to, cells, drugs, tissue, gels and polymers contained within the particle, with subsequent release of the therapeutic materials in situ, methods of fabricating the particle by folding a 2D precursor into the 3D particle, and the use of the particle in in-vivo or in-vitro applications The particle can be in any polyhedral shape and its surfaces can have either no perforations or nano/microscale perforations The particle is coated with a biocompatible metal, e g gold, or polymer e g parvlene, layer and the surfaces and hinges of the particle are made of any metal or polymer combinations. | 12-17-2009 |
David Hugo Gracias, Baltimore, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100326071 | RECONFIGURABLE LITHOGRAPHIC STRUCTURES - A lithographically structured device has an actuation layer and a control layer operatively connected to the actuation layer. The actuation layer includes a stress layer and a neutral layer that is constructed of materials and with a structure such that it stores torsional energy upon being constructed. The control layer is constructed to maintain the actuation layer substantially in a first configuration in a local environmental condition and is responsive to a change in the local environmental condition such that it permits a release of stored torsional energy to cause a change in a structural configuration of the lithographically structured device to a second configuration, the control layer thereby providing a trigger mechanism. The lithographically structured device has a maximum dimension that is less than about 10 mm when it is in the second configuration. | 12-30-2010 |
Vijaya J. Gracias, West Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090203690 | 5-SUBSTITUTED INDAZOLES AS KINASE INHIBITORS - The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, | 08-13-2009 |
| 20110105476 | SUBSTITUTED 7,8-DIHYDRO-1HPYRIMIDO[4,5-B]DIAZEPIN-4-AMINES ARE NOVEL KINASE INHIBITORS - Compounds having the Formula (I) | 05-05-2011 |