Gouveia
Catherine Elizabeth Gouveia, Witney GB
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20100190927 | MHC OLIGOMERS, COMPONENTS THEREOF, AND METHODS OF MAKING THE SAME - The present invention relates to an MHC binding polymer suitable for the oligomerisation of individual MHC monomers. The MHC binding polymer comprises a first segment and a second segment, wherein the first segment comprises a peptide capable of binding in a binding groove of an MHC molecule, and wherein the second segment comprises a linking segment and a recognition site for coupling the MHC binding polymer with a specific partner. The linking segment is a polymer with a length of at least 10 Angstrom in its native conformation. Further it relates to an MHC oligomer containing such MHC binding polymers. Individual functional MHC complex monomers are oligomerised via their peptides bound in the peptide binding groove of the complex. Moreover, it relates to a method of making such MHC binding polymer and oligomer and various methods using the same. | 07-29-2010 |
Catherine Elizabeth Gouveia, Whitney GB
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20080206789 | Method of Screening Mhc Molecules - The invention relates to a method for screening the binding properties of constituent peptides of MHC molecules by providing in solution MHC molecules or their constituent peptides for a set of MHC molecules including a plurality of subsets of MHC molecules, wherein the MHC molecules of each subset differ from MHC molecules of at least one other subset in at least one of the putative MHC binding peptide, an MHC alpha chain and an MHC beta chain, and loading said MHC molecules with an MHC binding peptide by (i) refolding of the MHC alpha chain and beta chain peptides in presence of said MHC binding peptide or (ii) by peptide exchange or loading with an unlabelled MHC binding peptide in the absence of any labelled MHC binding peptide, (b) taking of at least one sample from each subset, and (c) determining loading efficiency for the sample of step (b). | 08-28-2008 |
20120214185 | METHOD OF SCREENING MHC MOLECULES - The invention relates to a method for screening the binding properties of constituent peptides of MHC molecules by providing in solution MHC molecules or their constituent peptides for a set of MHC molecules including a plurality of subsets of MHC molecules, wherein the MHC molecules of each subset differ from MHC molecules of at least one other subset in at least one of the putative MHC binding peptide, an MHC alpha chain and an MHC beta chain, and loading said MHC molecules with an MHC binding peptide by (i) refolding of the MHC alpha chain and beta chain peptides in presence of said MHC binding peptide or (ii) by peptide exchange or loading with an unlabelled MHC binding peptide in the absence of any labelled MHC binding peptide, (b) taking of at least one sample from each subset, and (c) determining loading efficiency for the sample of step (b). | 08-23-2012 |
20120245332 | MHC OLIGOMERS, COMPONENTS THEREOF, AND METHODS OF MAKING THE SAME - The present invention relates to an MHC binding polymer suitable for the oligomerisation of individual MHC monomers. The MHC binding polymer comprises a first segment and a second segment, wherein the first segment comprises a peptide capable of binding in a binding groove of an MHC molecule, and wherein the second segment comprises a linking segment and a recognition site for coupling the MHC binding polymer with a specific partner. The linking segment is a polymer with a length of at least 10 Angstrom in its native conformation. Further it relates to an MHC oligomer containing such MHC binding polymers. Individual functional MHC complex monomers are oligomerised via their peptides bound in the peptide binding groove of the complex. Moreover, it relates to a method of making such MHC binding polymer and oligomer and various methods using the same. | 09-27-2012 |
20150293128 | METHOD OF SCREENING MHC MOLECULES - The invention relates to a method for screening the binding properties of constituent peptides of MHC molecules by providing in solution MHC molecules or their constituent peptides for a set of MHC molecules including a plurality of subsets of MHC molecules, wherein the MHC molecules of each subset differ from MHC molecules of at least one other subset in at least one of the putative MHC binding peptide, an MHC alpha chain and an MHC beta chain, and loading said MHC molecules with an MHC binding peptide by (i) refolding of the MHC alpha chain and beta chain peptides in presence of said MHC binding peptide or (ii) by peptide exchange or loading with an unlabelled MHC binding peptide in the absence of any labelled MHC binding peptide, (b) taking of at least one sample from each subset, and (c) determining loading efficiency for the sample of step (b). | 10-15-2015 |
Christian Mendez Gouveia, Buenos Aires AR
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20140379535 | METHODS AND APPARATUS TO MONITOR PRODUCTS IN STORES - Methods and apparatus are disclosed to audit products in stores. An example method includes receiving, at a collection entity, a first request from a first entity to audit a first product, the first request including a first instruction to determine information about a second product that competes with the first product, in response to the first request, assigning a first auditor to audit the first product and to record the information about the second product, receiving, at the collection entity, a second request from a second entity to audit a third product, determining that the second request includes a second instruction to determine information about the second product identified in the first request, and in response to the second request, assigning a second auditor to audit the third product without including a further instruction to record the information about the second product. | 12-25-2014 |
Christopher M. Gouveia, Honolulu, HI US
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20090204692 | System and Method for Network Device Configuration - Methods and systems for identifying configuration parameters for a network device are provided. The method includes generating a stream of traffic data, where the traffic data has a known characteristic. Then, applying the stream of traffic data to the network device, where the network device has a specific type, and the network device generates an output based on the traffic data. The method then includes monitoring performance of the network device while the traffic data is processed by the network device, and the monitoring is configured to generate monitoring data for the traffic data applied to the network device having the specific type. Also, the method includes analyzing the output from the network device, where the analyzing is performed to identify how the traffic data was handled by the network device, and the analyzing is configured to generate performance metrics. The method further includes saving the monitoring data and the performance metrics to a knowledge database. The knowledge database is capable of being accessed to enable configuration of other network devices based in part on the monitoring data and performance metrics. | 08-13-2009 |
Colin Gouveia, Fort Washington, PA US
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20090082409 | Steam stripping polymer dispersions to improve biocide stability - A process for stabilizing biocide compounds in a polymer dispersion requiring stripping of the dispersion using steam or an inert gas. | 03-26-2009 |
Colton Gouveia, Bristol, RI US
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20150308806 | SCORING TOOL - A scoring tool is disclosed that includes a body with a retractable tape therein and a tang on one end of the tape, the tang having a blade-receiving structure thereon configured and arranged to receive a blade of a utility knife therethrough. | 10-29-2015 |
Justin Gouveia, Monroe, CT US
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20150114772 | ROTOR BRAKE - A brake disc of a rotor brake is provided including a generally cylindrical body having a first planar surface, a second, opposite planar surface, and a central opening extending there through. A plurality of first connection members extend generally outwardly from the first planar surface. The first connection members are generally equidistantly spaced about a diameter of the first planar surface. A plurality of second connection members extend generally outwardly from the second planar surface. The second connection members are generally equidistantly spaced about a diameter of the second planar surface. | 04-30-2015 |
Maria Cristina Frazão Pissarra Gouveia, Lisboa PT
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20140137788 | Watercraft Automatic Bi-Planar Explorer - A watercraft is disclosed which has the ability to automatically adjust one of its planes in relation to a surface of water to achieve useful goals. | 05-22-2014 |
Paulo Gouveia, Everett, MA US
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20100116025 | AIR SAMPLER - An air sampler includes an inertial impactor with a compressible porous collector that receives particles greater than a lower threshold size from an air sample. Before reaching the collector, the air sample may pass through a sorter that prevents that removes particles above an upper threshold size. A mechanism transfers the compressible porous collector and base between the air sampler and a wash position outside of the air sampler. An agitator at the wash position may agitate the compressible porous collector to remove particles therefrom. The compressor may be wetted with various substances to facilitate particle collection from the air, preservation of particles on the collector, and removal of particles from the collector. | 05-13-2010 |