Gossage
David L. Gossage, Seattle, WA US
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20150239988 | ANTIBODIES TO MATRIX METALLOPROTEINASE 9 AND METHODS OF USE THEREOF - The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), such as where the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof). | 08-27-2015 |
David L. Gossage, Gaithersburg, MD US
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20120328606 | Methods Of Diagnosing And Treating Pulmonary Diseases Or Disorders - The present disclosure provides methods of diagnosing a subject as having a pulmonary disease or disorder, e.g., an eosinophilic disease or disorder based on the determination of white blood cell ratios. The disclosure also provides white blood cell ratio-based methods of treating, prognosing, or monitoring a pulmonary disease or disorder, as well as methods of methods of predicting a dosage regimen, identifying a candidate therapeutic agent, identifying a patient as a candidate for a therapeutic agent, and methods of designing a personalized therapy. | 12-27-2012 |
Garran M. Gossage, San Luis Obispo, CA US
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20110266076 | MOBILE ROBOT SYSTEMS AND METHODS - Mobile robot systems and methods are provided. At least one tracked mobile robot has a first end comprising a first pair of wheels, a second end comprising a second pair of wheels, an articulated arm coaxial with the first pair of wheels, and a driven support surface surrounding the first pair of wheels and the second pair of wheels. The at least one mobile robot surmounts obstacles and performs additional maneuvers alone and in combination with at least one other mobile robot. | 11-03-2011 |
20120200149 | RESILIENT WHEEL ASSEMBLIES - A wheel assembly for a remote vehicle comprises a wheel structure comprising a plurality of spokes interconnecting a rim and a hub. The spokes comprise at least one slit extending therethrough radially inward from the rim to the hub. The wheel assembly also comprises a flipper structure comprising an arm, a plurality of legs, and an attachment base. The plurality of legs and the attachment base comprise a four-bar linkage. The wheel assembly further comprises an insert comprising a bore with a flat surface that tapers outward from a top portion of the insert to a bottom portion of the insert. The insert may be configured to couple the flipper structure to the wheel structure via an axle on the remote vehicle and prevent backlash between the axle and the flipper structure. The flipper structure may be configured to transmit axial forces to the wheel structure. The wheel structure may be configured to absorb radial and axial forces. | 08-09-2012 |
Garren M. Gossage, San Luis Obispo, CA US
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20120199407 | Mobile Robot Systems and Methods - Mobile robot systems and methods are provided. At least one tracked mobile robot has a first end comprising a first pair of wheels, a second end comprising a second pair of wheels, an articulated arm coaxial with the first pair of wheels, and a driven support surface surrounding the first pair of wheels and the second pair of wheels. The at least one mobile robot surmounts obstacles and performs additional maneuvers alone and in combination with at least one other mobile robot. | 08-09-2012 |
Garron M. Gossage, San Luis Obispo, CA US
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20140110183 | SMALL UNMANNED GROUND VEHICLE - The present teachings relate generally to a small remote vehicle having rotatable flippers and a weight of less than about 10 pounds and that can climb a conventional-sized stairs. The present teachings also relate to a small remote vehicle can be thrown or dropped fifteen feet onto a hard/inelastic surface without incurring structural damage that may impede its mission. The present teachings further relate to a small remote vehicle having a weight of less than about 10 pounds and a power source supporting missions of at least 6 hours. | 04-24-2014 |
Kirk Gossage, Austin, TX US
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20150116567 | MULTIPLE CHANNEL MATCHING METHOD - A method for matching one or more channels to a reference channel in a multiple-channel detector having a digital output, the method including: receiving an analog-to-digital unit (ADU) input value from the multiple-channel detector for each channel; and replacing the ADU input value by an output value corresponding to each channel from a look up table (LUT); wherein the LUT is created by taking a relative intensity ratio of signals from each channel compared to the reference channel over a range of voltage values; calculating a signal value on the detector that generates a specific ADU value across the entire ADU range of the detector; interpolating the relative intensity ratios to obtain ratios corresponding to the calculated signal values for each channel; and dividing the each of the specific ADU value by the corresponding interpolated ratio to obtain the corresponding output value for each channel. | 04-30-2015 |
20150124119 | METHOD FOR CORRECTING IMAGES ACQUIRED VIA ASYNCHRONOUSLY TRIGGERED ACQUISITION - A method for correcting images acquired via an asynchronous triggered acquisition, wherein image acquisition is triggered by a trigger signal based on the motion and/or position of the sample to be imaged by an image sensor, the method including: measurement of the motion and/or position of the sample; determination of an exposure time based on the aforementioned measurement; and correction of an acquired image based on the determined exposure time and a desired exposure time. | 05-07-2015 |
Kirk William Gossage, Milford, CT US
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20090257640 | CLASSIFICATION OF SAMPLES - Methods disclosed herein include: (a) determining positions of a plurality of cells based on one or more images of the cells; (b) for at least some of the plurality of cells, generating a matrix that includes two-dimensional information about positions of neighboring cells, and determining one or more numerical features based on the information in the matrix; and (c) classifying the at least some of the plurality of cells as belonging to at least one of multiple classes based on the numerical features. | 10-15-2009 |
20140134713 | SPECTRAL IMAGING OF BIOLOGICAL SAMPLES - The invention features a method including: (i) providing spectrally resolved information about light coming from different spatial locations in a sample comprising deep tissue in response to an illumination of the sample, wherein the light includes contributions from different components in the sample; (ii) decomposing the spectrally resolved information for each of at least some of the different spatial locations into contributions from spectral estimates associated with at least some of the components in the sample; and (iii) constructing a deep tissue image of the sample based on the decomposition to preferentially show a selected one of the components. | 05-15-2014 |
20140376824 | CLASSIFYING IMAGE FEATURES - Methods are disclosed for classifying different parts of a sample into respective classes based on an image stack that includes one or more images. | 12-25-2014 |
20150056690 | SPECTRAL IMAGING OF BIOLOGICAL SAMPLES - The invention features a method including: (i) providing spectrally resolved information about light coming from different spatial locations in a sample comprising deep tissue in response to an illumination of the sample, wherein the light includes contributions from different components in the sample; (ii) decomposing the spectrally resolved information for each of at least some of the different spatial locations into contributions from spectral estimates associated with at least some of the components in the sample; and (iii) constructing a deep tissue image of the sample based on the decomposition to preferentially show a selected one of the components. | 02-26-2015 |
Kirk William Gossage, Manchester, NH US
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20080294032 | Spectral Imaging of Biological Samples - The invention features a method including: (i) providing spectrally resolved information about light coming from different spatial locations in a sample comprising deep tissue in response to an illumination of the sample, wherein the light includes contributions from different components in the sample; (ii) decomposing the spectrally resolved information for each of at least some of the different spatial locations into contributions from spectral estimates associated with at least some of the components in the sample; and (iii) constructing a deep tissue image of the sample based on the decomposition to preferentially show a selected one of the components. | 11-27-2008 |
20090245605 | SPECTRAL IMAGING OF BIOLOGICAL SAMPLES - The invention features a method including: (i) providing spectrally resolved information about light coming from different spatial locations in a sample comprising deep tissue in response to an illumination of the sample, wherein the light includes contributions from different components in the sample; (ii) decomposing the spectrally resolved information for each of at least some of the different spatial locations into contributions from spectral estimates associated with at least some of the components in the sample; and (iii) constructing a deep tissue image of the sample based on the decomposition to preferentially show a selected one of the components. | 10-01-2009 |
20090297016 | CLASSIFYING IMAGE FEATURES - Methods are disclosed for classifying different parts of a sample into respective classes based on an image stack that includes one or more images. | 12-03-2009 |
20110255753 | CLASSIFYING IMAGE FEATURES - Methods are disclosed for classifying different parts of a sample into respective classes based on an image stack that includes one or more images. | 10-20-2011 |
20130077875 | CLASSIFYING IMAGE FEATURES - Methods are disclosed for classifying different parts of a sample into respective classes based on an image stack that includes one or more images. | 03-28-2013 |
Matthew Gossage, Bellevue, WA US
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20100306444 | Free-Space Reduction in Cached Database Pages - A computing system stores a database comprising pages. Each of the pages is the same size. When a page is requested, a block of virtual memory addresses is associated with the page and a set of physical data storage locations is committed to the block of virtual memory addresses. A copy of the page is then stored into the set of physical data storage locations. Physical data storage locations committed to the virtual memory addresses associated with available free space in the copy of the page are deallocated, thereby allowing reuse of these physical data storage locations. A reference to the copy of the page is then returned. | 12-02-2010 |
Matthew G. Gossage, Bellevue, WA US
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20120159262 | EXTENDED PAGE PATCHING - The embodiments described herein generally relate to methods and systems for using an extended patching procedure for correction or repair of logical data portions, pages, or sectors of a computer data storage device. The extended patching procedure targets for repair not only the page(s) appearing to be defective or unusable based on a failed read operation for a data transfer request, but also additional pages. Determining the additional pages to include for automatic patching is based on: statistical distribution analyses to include pages within the physical or logical vicinity of the original page, information about the underlying storage device technology or Input/Output (I/O) subsystem, and/or historical data about error conditions for areas related to the original page. Preemptively patching pages based on extended page lists improves system performance by reducing the total number of costly repair processes and by avoiding situations involving correction actions that fail to resolve. | 06-21-2012 |
Roland Gossage, Toronto CA
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20150278902 | METHODS OF AUGMENTING SEARCH ENGINES FOR ECOMMERCE INFORMATION RETRIEVAL - Queries against search engines like the Google Search Appliance, Elastic Search and other readily available search engines to provide meaningful content for the purpose of supporting eCommerce websites. In particular, methods that provide for an intelligent abstraction to know when and how to generate a set of queries, the set of queries including one or more queries that are relevant to the searchable content are disclosed. In addition, the methods also can determine if a query against the search engine is even required and may redirect the use to other dynamic or static content outside the search index utilized by the search engine to satisfy the queries. | 10-01-2015 |