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Gormley, GB

Julie Gormley, Belfast GB

Patent application numberDescriptionPublished
20090269360THERAPY - The invention relates to a method of inhibiting chemotherapy induced upregulation of Cathepsin S on the surface of tumour cells, the method comprising the administration of a Cathepsin S inhibitor to said cells. Also provided is a therapy comprising an anti Cathepsin S antibody, in particular an anti-Cathepsin S antibody which does not inhibit the proteolytic effect of Cathepsin S but nevertheless inhibits angiogenesis and a combination treatment comprising a Cathepsin S inhibitor and a therapeutic agent.10-29-2009

Michael Gormley, Edinburgh GB

Patent application numberDescriptionPublished
20100000298METHOD AND EQUIPMENT FOR DETECTING SEALING DEFICIENCIES IN DRAINAGE AND VENT SYSTEMS FOR BUILDINGS - The method includes the following steps—introducing a low amplitude air pressure transient into the drainage and vent system of a building in order to propagate a pressure wave from a fitting (01-07-2010

Michael Gormley, Bournemouth GB

Patent application numberDescriptionPublished
20100028515RE-CARBONATING DEVICE - A carbonated drink container pressurizer adapter that is screwed onto a conventional drink container in place of the original bottle top, which includes a valve attachment point for the purpose of allowing entry of CO02-04-2010

Niall Gormley, Walden GB

Patent application numberDescriptionPublished
20080207460Determination of methylation of nucleic acid sequences - The invention relates to a method of detecting the precise locations of methyl-cytosines in a given nucleic acid sequence. In particular, the invention features a method which includes sequencing a template nucleic acid that is attached to a hairpin nucleic acid or double-stranded nucleic acid anchor, which contain specifically-designed sites for nicking or other endonucleases. The template nucleic acid is then regenerated to single-stranded form via methods described herein, and then treated to convert either the methylated cytosines, or non-methylated cytosines, and the template nucleic acid is then re-sequenced The results of the first and second sequencing reactions are then compared.08-28-2008

Niall Gormley, Nr. Saffron Walden GB

Patent application numberDescriptionPublished
20090148842Preparation of templates for methylation analysis - The invention relates to a method of preparing and using a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a method of preparing and analysing a library of template polynucleotides suitable for methylation analysis.06-11-2009

Simon Gormley, Scottish Borders GB

Patent application numberDescriptionPublished
20090240777METHOD AND SYSTEM FOR PROTECTING MESSAGING CONSUMERS - The present invention is directed to a system, method, and computer-program product for protecting messaging consumers. According to one embodiment of the invention, a method for protecting messaging consumers can be provided. The method can include intercepting a message prior to arrival at a destination, comparing the message to one or more known message structures to determine the message structure, and determining if a message has a valid message structure for the destination. Intercepting a message prior to arrival at a destination may intercepts a message on a queue before the message is consumed by a consumer. Comparing the message to known message structures compares a message to message schemas, for example, XML schema, Java object definition or C structure format.09-24-2009

Simon Gormley, Hursley Park GB

Patent application numberDescriptionPublished
20110107350MESSAGE ORDERING USING DYNAMICALLY UPDATED SELECTORS - A method of queuing messages for communications between a first computer program and a second computer program, comprises: placing a plurality of messages in a queue, wherein each message has a message body; placing selector information on each message, wherein the selector information contains information as to which message is to be processed next; and using the selector information on a message to identify a next message for processing.05-05-2011

Simon R. Gormley, Peebles GB

Patent application numberDescriptionPublished
20100179994PRESERVING MESSAGE ORDER USING A MESSAGE ORDERING MANAGER - A method and system for preserving a message ordering while processing message are discussed. A message ordering manager records an order in which electronic messages arrive at an input queue. An application server processes the electronic messages out-of-order or in parallel. The message ordering manager commits the processed electronic messages in the order in which electronic messages arrive at an input queue. If a processed message cannot be committed because older message(s) are not completely processed, then application server determines whether processing older message(s) is critical or not. If the processing the older message(s) is critical, the application server rolls back the processed message and the older message(s). Otherwise, the message ordering manager commits the processed message before the older electronic messages are committed.07-15-2010
20100312827METHOD AND APPARATUS TO ENABLE PROTOCOL VERIFICATION - After a client device issues a request, a verification stub component receives the request. Then, the verification stub component obtains a current state of the client device from a client state table. The verification stub component evaluates whether the request is valid or not by analyzing a content and context of the request and checking the request against a protocol matrix. If the request is valid, the verification stub component updates the current state of the client device in the current state table, and forwards the request to a server device. Otherwise, the verification stub component creates a report describing the request is invalid, and evaluates whether the server can process the request. If the server cannot process the request, the verification stub component interrupts the request and forwards the report to the client device. Otherwise, the verification stub component provides the request to the server device.12-09-2010