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Goral
David Goral, Brookfield, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110301553 | Antimicrobial lubricant - An antimicrobial lubricant combines an antimicrobial agent, preferably silver based, with a silicone lubricant. This is achieved by first formulating a lubricant solution that has a non-volatile silicone lubricant and a volatile solvent carrier. An antimicrobial agent is added to the lubricant solution. The solution is then subjected to ultrasonic energy so that the antimicrobial agent is uniformly mixed with the lubricant in the solution. The solution containing the antimicrobial lubricant may be sprayed onto a medical device, for example the outer surface of the catheter of a peripheral IV catheter. After the solvent flashes off, a coat of uniform antimicrobial lubricant is formed on the catheter surface. The antimicrobial lubricant coating facilitates the insertion of the catheter to a patient, and at the same time prevents the growth of microorganisms from the device and infection to the patient. | 12-08-2011 |
David J. Goral, Brookfield, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110319825 | CATHETER ASSEMBLY WITH SEAL MEMBER - A catheter assembly includes a catheter hub defining an interior cavity and a catheter tube extending distally thereof. A rigid actuator extends proximally in the interior cavity and supports a seal member thereon. The seal member includes a central membrane, a distal portion, and a proximal portion. An hourglass shaped actuator cavity is formed in the distal portion and receives a barbed end of the actuator. The outer surface of the seal member is in partial circumferential engagement with the catheter hub to define an air path that allows fluid communication between areas of the interior cavity distal and proximal of the seal member. A punch tool is provided to form a tri-slit in the membrane of the seal member. The seal member may be configured for multi-use and include a biasing member that moves the seal member to force the membrane back over the actuator to close the membrane. | 12-29-2011 |
| 20110319838 | Catheter Assembly with Seal Member - A catheter assembly includes a catheter hub defining an interior cavity and a catheter tube extending distally thereof. A rigid actuator extends proximally in the interior cavity and supports a seal member thereon. The seal member includes a central membrane, a distal portion, and a proximal portion. An hourglass shaped actuator cavity is formed in the distal portion and receives a barbed end of the actuator. The outer surface of the seal member is in partial circumferential engagement with the catheter hub to define an air path that allows fluid communication between areas of the interior cavity distal and proximal of the seal member. A punch tool is provided to form a tri-slit in the membrane of the seal member. | 12-29-2011 |
Jack Goral, Woodridge, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100091676 | Multi-Segment Network Application Monitoring and Correlation Architecture - A system, method and computer program product are provided for network and network application monitoring. Accordingly, one or more media modules are each coupled to an associated network segment. In the case of network application monitoring, each media module is coupled to a network segment on which a network application is running. Each media module monitors and collects data relating to traffic on the associated network segment corresponding to the network application, wherein each media module is tailored for network analysis. An application server module is coupled to the at least one media module and receives the data and analyzes the data for helping to improve the performance of the network and/or network application. | 04-15-2010 |
Thomas M. Goral, Oakland Twp, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20090309387 | PLASTIC CRUSH COUNTERMEASURE FOR VEHICLES - A plastic crush countermeasure for motor vehicles that includes a plastic insert and a reinforcement structure that provides impact and/or reinforcement characteristics and an attachment interface to the vehicle in a lighter weight structure. The crush countermeasure provides a lightweight crush system that provides comparable protection to current metal crush countermeasures using, in part, a plastic material. As such, the overall weight of a vehicle is reduced without any reduction in safety to passengers. | 12-17-2009 |
Vasiliy N. Goral, Ithaca, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090098540 | RECIRCULATING MICROFLUIDIC DEVICE AND METHODS OF USE - The present invention relates to a microfluidic test device for detecting or quantifying an analyte in a test sample. The device includes a non-absorbent substrate having at least one microchannel imbedded in the substrate, a non-specific capture device, and one or more stationary mixing structures extending into the at least one microchannel. The present invention also relates to relates to various methods of using the microfluidic test device to detect or quantify an analyte in a test sample. The present invention also relates to a microfluidic device that includes a non-absorbent substrate having at least one microchannel imbedded in the substrate and one or more stationary mixing structures extending into the at least one microchannel. | 04-16-2009 |
Vasiliy N. Goral, Painted Post, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100130829 | MATERIALS AND METHODS FOR DETECTING EARLY CELL MIGRATION EVENTS - Aspects relate to the field of label-free biosensors, including optical biosensors and electric biosensors, for studying cellular behaviour particularly early events in cell migration, under a concentration gradient of stimulus. Various embodiments include devices and methods that enable the generation of a concentration gradient of stimulus for cells contacting with the surface of a biosensor including a label free biosensor. Some aspects also disclose methods to detect cellular responses upon such concentration gradient of a stimulus, as well as methods to detect the potency and efficacy of a stimulus using a single biosensor. | 05-27-2010 |
| 20110086427 | MICROFLUIDIC DEVICE FOR CELL CULTURE - A microfluidic cell culture apparatus includes a cell retention chamber and a perfusion channel. The cell retention chamber has a structured surface. The structured surface includes a major surface from which a plurality of projections extends into the chamber. The plurality of projections are arranged to suspend cells cultured in the chamber above the major surface. The first perfusion channel is configured to provide laminar flow of a fluid through the channel and forms a plurality of openings in communication with the cell retention chamber. The openings are configured to prevent cells from the retention chamber from entering the perfusion channel. | 04-14-2011 |
Vasiliy Nikolaevich Goral, Painted Post, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100129856 | Methods and Devices for Cell Signaling Under Pulse Stimulation - The disclosure provides a device for measuring cellular responses under controlled environments. The disclosure also provides an array of devices for measuring cellular responses under controlled environments. The disclosure also provides methods to study cell signaling using the devices. By using microfluidics, the disclosure enables study of cell signaling under well-defined environment conditions. Such capability can be used for differentiating long-acting ligands from short-acting ligands, for determining the kinetics of receptor resensitization and functional recovery of receptor signaling, and for differentiating the sensitivity of a cell type to laminar flow-induced stress force. Through combination with conventional static label-free cell assays, the full spectrum of a drug compound can be studied in details, thus creating a complete representation of its pharmacology acting on living cells. | 05-27-2010 |