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Goodman, CA

Amy Goodman, San Francisco, CA US

Patent application numberDescriptionPublished
20110230932DEVICE AND METHOD FOR INDEPENDENTLY STIMULATING HEMIDIAPHRAGMS - A device and method for treating a subject is provided where electrical stimulation may be separately provided to each hemidiaphragm to cause diaphragm contraction. Fatigue may be avoided among other possible benefits. Each hemidiaphragm may also be stimulated with different stimulation parameters. Stimulation may be smoothly transitioned between hemidiaphragms. Such stimulation may provide an increase in functional residual capacity or other therapeutic effects.09-22-2011

Amy M. Goodman, San Francisco, CA US

Patent application numberDescriptionPublished
20100152531IMPLANTABLE MEDICAL DEVICE FOR DRUG DELIVERY AND METHOD OF USE - An apparatus and method of preparing a cardiac harness for use in controllably delivering a medicament such as an mTOR inhibitor or aldosterone blockade from the surface of the cardiac harness to the epicardium of a patient's heart for the site-specific treatment of cardiac and non-cardiac maladies. The delivery of the medicament from the cardiac harness is achieved by: coating the medicament on the surface of the cardiac harness; coating the cardiac harness with a polymer material or dielectric material and impregnating the coating with the medicament; or by loading the medicament into an implant attached to the cardiac harness.06-17-2010

Amy Michelle Goodman, San Francisco, CA US

Patent application numberDescriptionPublished
20080208281Device and method for biasing and stimulating respiration - A device and method is provided for biasing lung volume by electrically stimulating tissue associated with the diaphragm or phrenic nerve at a low level.08-28-2008

Andrew Goodman, Portola Valley, CA US

Patent application numberDescriptionPublished
20090316895CONDITIONAL ACCESS SYSTEM AND METHOD FOR PREVENTION OF REPLAY ATTACKS - In a conditional access system, a headend transmits content to one or more receivers in encrypted transport streams. The system provides a multi-layer security architecture, rendering the system resistant to key replay attacks; if one layer is circumvented, subsequent layers remain intact. A first layer prevents unencrypted keys from being recorded by shielding the unencrypted keys from users and encrypting the path from the receiver's conditional access module to the transport decryption module; a second layer prevents a key recorded on one receiver from being played back to the transport decryption module on a second receiver; a third layer prevents a user from decrypting transport streams without the encryption module by encrypting the stream a second time prior to being passed through any user-accessible memory or processor.12-24-2009

Andrew M. Goodman, Portola Valley, CA US

Patent application numberDescriptionPublished
20090019468Access control of media services over an open network - To ensure that media services are only provided to those authorized users or receiving devices, various conditional access mechanisms are provided to secure that media services are only received in those authorized. Different from a prior art conditional access system, an entitlement control message containing a master key can be sent directly to an ordering box. Depending on implementation, a secure session may be established between a server and an ordering box, such that all secured information including a master key may be transported. Further an ordering box does not need to possess a key or keys needed to decrypt an entitlement control message, such key(s) may be transported from time to time in a secure session established between the server and the ordering box.01-15-2009
20090024846Secured seeding of data in a distributed environment - Techniques for seeding data among client machines, also referred to as boxes herein, are disclosed. To prevent the data distributed among the boxes from being illegitimately accessed or possessed, according to one aspect of the present invention, each box is configured to perform what is referred to herein as a transcription process. In other words, when encrypted data is received, the data is decrypted and then re-encrypted with a key agreeable with a next box configured to receive the data.01-22-2009
20090031424Incomplete data in a distributed environment - Techniques for seeding data among client machines, also referred to as boxes herein, are disclosed. To prevent the data distributed among the boxes from being illegitimately accessed or possessed, according to one aspect of the present invention, at least one of the data segments for a title cached locally in the boxes is made to miss some data portions that are stored separately. Essentially, the data segments are unusable without these data portions. When the title is ordered and an ordering box is authenticated, these data portions are then provided to complement the data segments so that a playback of the title becomes possible.01-29-2009
20090256718MULTIMEDIA MOBILE PERSONALIZATION SYSTEM - A multimedia mobile personalization system provides a remote control that detects a user's electronic tag, e.g. an RFID tag. The remote control notifies a multimedia device of the user's identity. The multimedia devices tailors it operations to the user's preferences stored locally. Multimedia content such as broadcast or recorded television programs, music play lists, and the like could be sorted, displayed, or restricted, depending on the user identifier.10-15-2009
20090259939MULTIMEDIA MOBILE PERSONALIZATION SYSTEM - A multimedia mobile personalization system provides a remote control that detects a user's electronic tag, e.g. an RFID tag. The remote control notifies a multimedia device of the user's identity. The multimedia devices tailors it operations to the user's preferences stored locally. Multimedia content such as broadcast or recorded television programs, music play lists, and the like could be sorted, displayed, or restricted, depending on the user identifier.10-15-2009
20100319014Multimedia Mobile Personalization System - A multimedia mobile personalization system allows a user to record and play multimedia content on a set top box at a location other than his home using the user's preferences from his home DVR.12-16-2010
20110023072MULTIPLE AUDIO STREAMS - A system and method for providing multiple audio streams for a video over a network such as the Internet. The system comprises a server that includes an encryption unit and a slicing unit, a plurality of boxes, and an ordering box. The server encodes multiple audio streams and a single video to be sliced into segments. The sliced segments of multiple audio streams and the single video are seeded to a number of the plurality of boxes. This may be repeated for other videos with multiple streams. When the ordering box makes a request for a single video with a single audio, then the number of boxes with segments of the requested video and multiple audio streams, filters and sends the requested video and requested single audio stream to the ordering box. Similarly, multiple closed caption streams can be handled and provided like the audio streams.01-27-2011

Patent applications by Andrew M. Goodman, Portola Valley, CA US

Andrew Martin Goodman, Portola Valley, CA US

Patent application numberDescriptionPublished
20090208185MULTIPLE OUTPUT DIGITAL VIDEO RECORDING SYSTEM - A multimedia time warping system allows a user to store selected multimedia data streams while the user is simultaneously watching or reviewing other multimedia data. Data streams are converted to digital streams for internal transfer and manipulation. A parser and event buffer decouple the CPU from having to parse the digital stream. Video segments are stored on a storage device and when data is requested for display, its video segments are extracted from the storage device and sent to a decoder that converts them into display output signals and delivers the display output signals to a display.08-20-2009
20090269024MULTIMEDIA SIGNAL PROCESSING SYSTEM - A multimedia signal processing system utilizes an easily manipulated, low-cost storage and display system that allows the user to view a television program and instantly review previous scenes within the program. The invention also allows the user to store selected programs while simultaneously watching or reviewing another. A versatile system architecture enables providing the invention in multiple configurations, each adapted to receive input signals from a different source. At the highest level, the system includes an input section and an output section. Across all configurations, the output section remains substantially the same, while the input section varies according to the signal type and the source. Thus, several configurations are provided, each one requiring only minor system board modifications. The system architecture thus simplifies the design and manufacturing challenge presented by producing units to serve different markets, such as digital satellite, digital cable and analog cable.10-29-2009
20090269031MULTIMEDIA STREAM PROCESSING SYSTEM - A multimedia signal processing system allows a user to store selected programs while simultaneously watching or reviewing another. The system includes an input section and an output section. Across all configurations, the output section remains substantially the same, while the input section varies according to the signal type and the source. The system receives a digital stream and simultaneously processes the digital stream for display and stores the digital stream on at least one storage device. The system further simultaneously processes a previously recorded digital stream for display while processing the digital stream for display.10-29-2009
20100226627Multimedia Stream Processing System - A multimedia signal processing system allows a user to store selected programs while simultaneously watching or reviewing another. The system includes an input section and an output section. Across all configurations, the output section remains substantially the same, while the input section varies according to the signal type and the source. The system receives a digital stream and simultaneously processes the digital stream for display and stores the digital stream on at least one storage device. The system further simultaneously processes a previously recorded digital stream for display while processing the digital stream for display.09-09-2010

Andrew Martin Goodman, Menlo Park, CA US

Patent application numberDescriptionPublished
20080288998MULTIMEDIA SIGNAL PROCESSING SYSTEM - A multimedia signal processing system utilizes an easily manipulated, low-cost storage and display system that allows the user to view a television program and instantly review previous scenes within the program. The invention also allows the user to store selected programs while simultaneously watching or reviewing another. A versatile system architecture enables providing the invention in multiple configurations, each adapted to receive input signals from a different source. At the highest level, the system includes an input section and an output section. Across all configurations, the output section remains substantially the same, while the input section varies according to the signal type and the source. Thus, several configurations are provided, each one requiring only minor system board modifications. The system architecture thus simplifies the design and manufacturing challenge presented by producing units to serve different markets, such as digital satellite, digital cable and analog cable.11-20-2008
20090136215DIGITAL VIDEO RECORDER SYSTEM WITH AN INTEGRATED DVD RECORDING DEVICE - A digital video recorder (DVR) system with an integrated DVD recording device accepts TV input streams in a multitude of forms. Analog TV streams are converted to an MPEG formatted stream for internal transfer and manipulation, while pre-formatted MPEG streams are extracted from the digital TV signal and presented in a similar format. Indexes within the MPEG stream are determined and saved at predefined intervals and are stored on a hard disk along with the MPEG program material and used to create navigation packets when writing to a DVD inserted in an integrated DVD player/recorder. When a program is requested for display from the hard disk or the integrated DVD player/recorder, the program material are extracted from the appropriate source and reassembled into an MPEG stream which is sent to a decoder. The decoder converts the MPEG stream into TV output signals and delivers the TV output signals to a TV monitor. User control commands are accepted which affect the flow of the MPEG stream allowing the user to view stored programs with special functions: reverse, fast forward, play, pause, index, fast/slow reverse play, and fast/slow play. The user can select program material stored on the hard disk to be written to a DVD and can also select program material stored on a DVD to be transferred to the hard disk.05-28-2009
20100142920Multimedia Signal Processing System - A multimedia signal processing system utilizes an easily manipulated, low-cost storage and display system that allows the user to view a television program and instantly review previous scenes within the program. The invention also allows the user to store selected programs while simultaneously watching or reviewing another. A versatile system architecture enables providing the invention in multiple configurations, each adapted to receive input signals from a different source. At the highest level, the system includes an input section and an output section. Across all configurations, the output section remains substantially the same, while the input section varies according to the signal type and the source. Thus, several configurations are provided, each one requiring only minor system board modifications. The system architecture thus simplifies the design and manufacturing challenge presented by producing units to serve different markets, such as digital satellite, digital cable and analog cable.06-10-2010

Patent applications by Andrew Martin Goodman, Menlo Park, CA US

Corey S. Goodman, Berkeley, CA US

Patent application numberDescriptionPublished
20080312158Semaphorin Gene Family - A novel class of proteins, semaphorins, nucleic acids encoding semaphorins, semaphorin peptides, and methods of using semaphorins and semaphorin-encoding nucleic acids are disclosed. Semaphorin peptides and receptor agonists and antagonists provide potent modulators of nerve cell growth and regeneration. The invention provides pharmaceutical compositions, methods for screening chemical libraries for regulators of cell growth/differentiation; semaphorin gene-derived nucleic acids for use in genetic mapping, as probes for related genes, and as diagnostic reagents for genetic neurological disease; specific cellular and animal systems for the development of neurological disease therapy.12-18-2008
20090155928Modulating robo: ligand interactions - Disclosed are methods and compositions for identifying agents which modulate the interaction of Robo and a Robo ligand and for modulating the interaction of Robo and a Robo ligand. The methods for identifying Robo:ligand modulators find particular application in commercial drug screens. These methods generally comprise (1) combining a Robo polypeptide, a Slit polypeptide and a candidate agent under conditions whereby, but for the presence of the agent, the Robo and Slit polypeptides engage in a first interaction, and (2) determining a second interaction of the Robo and Slit polypeptides in the presence of the agent, wherein a difference between the first and second interactions indicates that the aget modulates the interaction of the Robo and Slit polypeptides. The subject methods of modulating the interaction of Robo and a Robo ligand involve combining a Robo polypeptide, a Slit polypeptide and a modulator under conditions whereby, but for the presence of the modulator, the Robo and Slit polypeptides engage in a first interaction, whereby the Robo and Slit polypeptides engage in a second interaction different from the first interaction. In a particular embodiment, the modulator is dominant negative form of the Robo or Slit polypeptide.06-18-2009
20100233819ROBO: A NOVEL FAMILY OF POLYPEPTIDES AND NUCLEIC ACIDS - Robo1 and Robo2 polypeptides may be produced recombinantly from transformed host cells from the disclosed Robo encoding nucleic acids or purified from human cells. The invention provides isolated Robo hybridization probes and primers capable of specifically hybridizing with the disclosed Robo genes, Robo-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.09-16-2010

Patent applications by Corey S. Goodman, Berkeley, CA US

David Edward Goodman, Greenbrae, CA US

Patent application numberDescriptionPublished
20110028809PATIENT MONITOR AMBIENT DISPLAY DEVICE - Embodiments of the disclosure include an orb or lamp communicating with a noninvasive monitor to provide a readily identifiable point indication of a wellness of a monitored patient. In an embodiment the orb emits a color gradient from a first color through at least two other colors responsive to values of a wellness measurement. Exemplary wellness indications include one or a statistical combination of blood constituent measurements, combinations of other physiological parameters, or the like.02-03-2011

Dennis M. Goodman, Danville, CA US

Patent application numberDescriptionPublished
20100060509MODEL-BASED TOMOGRAPHIC RECONSTRUCTION - A model-based approach to estimating wall positions for a building is developed and tested using simulated data. It borrows two techniques from geophysical inversion problems, layer stripping and stacking, and combines them with a model-based estimation algorithm that minimizes the mean-square error between the predicted signal and the data. The technique is designed to process multiple looks from an ultra wideband radar array. The processed signal is time-gated and each section processed to detect the presence of a wall and estimate its position, thickness, and material parameters. The floor plan of a building is determined by moving the array around the outside of the building. In this paper we describe how the stacking and layer stripping algorithms are combined and show the results from a simple numerical example of three parallel walls.03-11-2010

Elizabeth Goodman, San Francisco, CA US

Patent application numberDescriptionPublished
20090254840LOCAL MAP CHAT - Information communication technology operable to provide users with a means for sharing information and comments is disclosed. The information communication technology provides a means for participants to place chat comments on an interactive graphic such as a dynamically rendered map that participants can track, edit and collaboratively work with in order to decide on a suitable meeting location.10-08-2009

Garry Goodman, Los Angeles, CA US

Patent application numberDescriptionPublished
20100236373Clamping Ball End for Musical Strings - This invention relates to a ball-ender apparatus for securing to a pre-selected length wire by passing through the apparatus and being secured by a precision screw from which the wire receives medial pressure locking the wire in place. Without an expensive winding machine or winding of wire or even modifications made to musical instruments, wire can be tensioned, after the precision screw is screwed onto the wire within the clamping ball end housing to securely hold the wire in place.09-23-2010

Greg Goodman, Santa Barbara, CA US

Patent application numberDescriptionPublished
20090259630System and Method for Generating a Unified Service Model - The present disclosure is directed to a method and system for generating a unified service model. In accordance with a particular embodiment of the present disclosure, configuration items are received. The configuration items include configuration data for at least one service. Key indicators are received. The key indicators include metrics for the performance of the service. At least one association is identified between the configuration items and the key indicators. A unified service model is generated based on the association. The unified service model includes at least a graphical representation of the service and service requirements.10-15-2009

James P. Goodman, Valencia, CA US

Patent application numberDescriptionPublished
20110103627SOUND PROCESSORS AND IMPLANTABLE COCHLEAR STIMULATION SYSTEMS INCLUDING THE SAME - Sound processors and systems including sound processors are disclosed.05-05-2011

James Paul Goodman, Valencia, CA US

Patent application numberDescriptionPublished
20110266384REEL BASED LACING SYSTEM - A reel based lacing system is disclosed. The reel can be configured to allow the incremental tightening of a lace about a spool by rotation of a knob in the tightening direction. In some embodiments, the system can include a substantially inflexible pawl beam configured to resist rotation of the knob in the loosening direction and a pawl spring configured to bias the pawl against the housing and to allow the pawl to be displaced away from the housing when the knob is rotated in the tightening direction.11-03-2011

Laurie Goodman, El Granada, CA US

Patent application numberDescriptionPublished
20100210034METHODS OF DETERMINING PATIENT RESPONSE BY MEASUREMENT OF HER-3 - The invention provides methods of measuring and/or quantifying the presence and/or amount of Her-3 and/or Her-3 in a complex in a sample. The invention also provides antibodies specific for Her-3.08-19-2010
20100233732Methods of Determining Patient Response By Measurement of HER-2 Expression - Methods are provided for determining or otherwise assessing the response of a patient to treatment, in particular, to cancer treatment. The methods include the analysis of samples for the presence or the absence of HER2 markers alone or in conjunction with other biomarkers, such as HER3 markers. In certain examples, the probable time to progression can be determined by first determining HER2 positive patients and then further stratifying by using the presence or the absence of a second biomarker (e.g, HER3 markers). In addition, the data can be used to track a patient's response to a treatment regimen, assessing the expected success of treating a patient using a particular regiment, determining the effects of a treatment regiment or for categorizing a patient in order to create a homogenous group for a clinical trial.09-16-2010

Marissa Goodman, San Francisco, CA US

Patent application numberDescriptionPublished
20100070529SYSTEM AND METHOD FOR USING SUPPLEMENTAL CONTENT ITEMS FOR SEARCH CRITERIA FOR IDENTIFYING OTHER CONTENT ITEMS OF INTEREST - Supplemental content, such as advertisement media and promotional content, may be presented as seeds from which additional, highly relevant supplemental content may be provided to the user. The highly relevant supplemental content may be determined from criteria that is generated or associated with image content (and text and/or metadata) of the seed supplemental content.03-18-2010

Michael K. Goodman, Irvine, CA US

Patent application numberDescriptionPublished
20090167962Computer Monitors - A computer monitor has an input for receiving from a general-purpose computer a video signal representing a video image, a screen, and a driver for causing the screen to display a video image represented by a video signal. The monitor further includes storage for storing video and/or picture data, a processor for retrieving video and/or picture data from the storage means and producing a video signal therefrom, and a switch for switching the monitor between (i) a first “monitor” mode in which the driver causes the screen to display the video image represented by the signal received by the input and (ii) a second “media player” mode in which the driver causes the screen to display the video and/or picture image represented by the signal produced by the processor. This therefore provides the functionality of a media player in a computer monitor so that, when the monitor is not being used for displaying the video output from the general-purpose computer, it can be used instead as a media player, reducing number of the main pieces of equipment required, and enabling the general-purpose computer to be switched off and therefore to conserve energy when merely the media playing functions are required.07-02-2009

Murray Goodman, La Jolla, CA US

Patent application numberDescriptionPublished
20080221020Dendrimers as Molecular Translocators - Transport molecules include a dendrimer and a biologically active molecule. The dendrimer of such transport molecules includes at least one guanidine group, at least one protonated guanidine group, at least one protected guanidine group, at least one amidine group, at least one protonated amidine group, at least one protected amidine group, at least one ureido group, at least one protonated ureido group, at least one protected ureido group, at least one thioureido group, at least one protonated thioureido group, or at least one protected thioureido group. The biologically active molecule is bonded to the dendrimer. A method of increasing the bioavailability of a drug includes bonding the drug to a dendrimer of the invention.09-11-2008
20110243845SOMATOSTATIN ANALOGS WITH INHIBITORY ACTIVITY TO GROWTH HORMONE RELEASE - Provided are therapeutic and diagnostic somatostatin analogs including radiotherapeutic and radiodiagnostic reagents, and methods of making and use thereof.10-06-2011

Patent applications by Murray Goodman, La Jolla, CA US

Myron Goodman, La Canada, CA US

Patent application numberDescriptionPublished
20090163422THREE-DIMENSIONAL STRUCTURE OF THE APOBEC 2 STRUCTURE, USES THEREOF, AND METHODS FOR TREATING CHRONIC AND INFECTIOUS DISEASES - Three-dimensional structure of APOBEC-2 and other structure models of APOBEC proteins obtained by computer modeling that bear similarity with a root-mean-square deviation (RMSD) of 2.0 with the APOBEC-2 monomer, dimer or tetramer. Uses of the three-dimensional structure of APOBEC-2 and models of APOBEC proteins particularly for structure-based drug design of compounds, peptides or mutant APOBEC proteins designed to treat Hyper-IgM-2 Syndrome, B cell lymphomas and lentivirus infections, particularly the human immunodeficiency virus (HIV) infection. Methods for identifying a compound that binds to any fragment of an APOBEC protein. The method includes obtaining the three dimensional structure of the APOBEC-2 monomer, dimer or tetramer and identifying or designing one or more compounds that bind, mimic, enhance, disrupt, or compete with interactions of APOBEC family proteins with themselves, their nucleic acid substrates and other cellular or viral proteins based on the three dimensional structure of the APOBEC-2 protein.06-25-2009

Myron F. Goodman, Los Angeles, CA US

Patent application numberDescriptionPublished
20100081621Crystal structure of the catalytic domain of the viral restriction factor APOBEC3G - The structure, function and methods associated with proteins from the APOBEC family, which are involved in diverse biological functions, is disclosed. In one embodiment, the structure of APOBEC-3G (Apo3G) is disclosed. In another embodiment, a method of using APOBEC-3G (Apo3G) and/or Apo3G-CD2 to restrict the replication of Human Immunodeficiency Virus (HIV) and Hepatitis B virus (HBV) via cytidine deamination on ssDNA or RNA binding is disclosed. In yet another embodiment, the high-resolution crystal structure of an enzymatically active APOBEC protein, the C-terminal deaminase domain of Apo3G (Apo3G-CD2) is disclosed.04-01-2010

Robert Goodman, Bodega Bay, CA US

Patent application numberDescriptionPublished
20090023120PROGRAM TO INTENSIVELY TEACH A SECOND LANGUAGE USING ADVERTISEMENTS - An immersion method teaches a student conversational speech aspects of a language (such as a second language) while, in the process, intensively exposing the student to a relevant conversational program (such as advertising) as an integral part of the teaching process. The method may include displaying, to the user/student, portions of video and audio of a conversational program (such as an advertisement in a second language), while causing a textual indication of the displayed audio to be simultaneously displayed (e.g., in the second language and a native language). The user may be prompted for information indicative of comprehension of the program by the user. Particularly in the case of advertising, information indicative of comprehension of the program can be very useful to the advertiser, as well as the prompting process itself serving to reinforce themes presented in the advertisement.01-22-2009

Rod Goodman, Long Beach, CA US

Patent application numberDescriptionPublished
20090216571SPORTS AND CONCERT EVENT TICKET PRICING AND VISUALIZATION SYSTEM - A system and method is presented for determining at what price and when to release so-called ‘flex’ price tickets during an on-sale using hazard functional analyses of sales velocity and sales/inquiry ratios. Exponential, power, and Weibull-gamma models are also used to predict demand, depending on what part of the on-sale is involved. Determining demand of seats from secondary markets is also described with methods to use the demand for either repricing the seats in the primary market or presenting ‘best value’ seats to a prospective purchaser. Demand can be interpolated or extrapolated to individual seats or rows.08-27-2009

Rodney M. Goodman, Altadena, CA US

Patent application numberDescriptionPublished
20090309614TECHNIQUES AND SYSTEMS FOR ANALYTE DETECTION - Techniques are used to detect and identify analytes. Techniques are used to fabricate and manufacture sensors to detect analytes. An analyte (12-17-2009

Rodney M. Goodman, South Pasadena, CA US

Patent application numberDescriptionPublished
20090102656Active ID tags for increased range and functionality - An RFID tag that uses multiple components to both receive and send information.04-23-2009

Ron Goodman, Santa Cruz, CA US

Patent application numberDescriptionPublished
20110314377AUTOMATIC HIERARCHICAL CATEGORIZATION OF MUSIC BY METADATA - A method, performed by software executing on the processor of a portable music playback device, that automatically files tracks according to hierarchical structure of categories to organize tracks in a logical order. A user interface is utilized to change the hierarchy, view track names, and select tracks for playback or other operations. The user interface uses an overlapping hierarchy of categories. A song title can be accessed in multiple different ways by starting with different categories. A preferred embodiment of the invention uses the top-level categories “Albums”, “Artists”, “Genres” (or styles), and “Play Lists”. Within the Albums category are names of different albums of songs stored in the device. Within each album are the album tracks, or songs, associated with that album. Navigation is performed by presenting a sequence of display screens for each level of the hierarchy.12-22-2011

Steven D. Goodman, Los Angeles, CA US

Patent application numberDescriptionPublished
20110236306COMPOSITIONS AND METHODS FOR THE REMOVAL OF BIOFILMS - This invention provides isolated or recombinant polypeptides that are useful to vaccinate individuals suffering from chronic/recurrent biofilm disease or as a therapeutic for those with an existing infection. The individual's immune system will then naturally generate antibodies which prevent or clear these bacteria from the host by interfering with the construction and or maintenance of a functional protective biofilm. Alternatively, antibodies to the polypeptides can be administered to treat or prevent infection. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system.09-29-2011

Steven D. Goodman, Redondo Beach, CA US

Patent application numberDescriptionPublished
20110032511SYSTEM AND METHOD TO MEASURE NANO-SCALE STRESS AND STRAIN IN MATERIALS - A system for measuring stress and strain in a sample is provided. The system includes a sample holder operable to support the sample; a stress inducing assembly operable to apply force to a selected location on the sample to deform the sample by a selected distance in a range from about 0.1 angstrom to about a millimeter; and an interferometer operable to determine a surface topography of the deformed sample at a resolution in a range from about 0.1 angstrom to about a micron.02-10-2011

Patent applications by Steven D. Goodman, Redondo Beach, CA US

Stuart B. Goodman, Stanford, CA US

Stuart B. Goodman, Los Altos, CA US

Patent application numberDescriptionPublished
20090088846Hydrogel arthroplasty device - An arthroplasty device is provided having an interpenetrating polymer network (IPN) hydrogel that is strain-hardened by swelling and adapted to be held in place in a joint by conforming to a bone geometry. The strain-hardened IPN hydrogel is based on two different networks: (1) a non-silicone network of preformed hydrophilic non-ionic telechelic macromonomers chemically cross-linked by polymerization of its end-groups, and (2) a non-silicone network of ionizable monomers. The second network was polymerized and chemically cross-linked in the presence of the first network and has formed physical cross-links with the first network. Within the IPN, the degree of chemical cross-linking in the second network is less than in the first network. An aqueous salt solution (neutral pH) is used to ionize and swell the second network. The swelling of the second network is constrained by the first network resulting in an increase in effective physical cross-links within the IPN.04-02-2009

Wilbert B. Goodman, Trabuco Canyon, CA US

Patent application numberDescriptionPublished
20100314435UNIVERSAL TWO-CELL STORAGE BOX - A universal shoe box has plural faces formed of a common continuous material with each face having a preferential fold disposed between adjacent faces which enable the quick assembly and disassembly of the shoe box. The shoe box includes a display window to enable quick and efficient visual identification of the contents of the shoe box on an image/photograph depicted on a card which may be disposed within the window. Two embodiments of the shoe box are presented, one primarily suited for residential/after market usage and one primary suitable for retail storage usage.12-16-2010

Wilbert Blair Goodman, Trabuco Canyon, CA US

Patent application numberDescriptionPublished
20100314268UNIVERSAL SHOE BOX - A universal shoe box has plural faces formed of a common continuous material with each face having a preferential fold disposed between adjacent faces which enable the quick assembly and disassembly of the shoe box. The shoe box includes a display window to enable quick and efficient visual identification of the contents of the shoe box on an image/photograph depicted on a card which may be disposed within the window. Two embodiments of the shoe box are presented, one primarily suited for residential/after market usage and one primary suitable for retail storage usage.12-16-2010

William Goodman, Los Altos, CA US

Patent application numberDescriptionPublished
20100033344ELECTRIC DIPOLE TRANSMISSION SYSTEM - An electric dipole transmission system includes an uphole dipole assembly adapted for receiving downhole telemetry data. The uphole dipole assembly includes a gap sub, an electric dipole transmitter, a battery stack and a wireline receiver. A short hop receiver assembly is connected to the lower end of the uphole dipole assembly by a wireline. A downhole dipole assembly operatively connected to the uphole dipole assembly includes a short hop transmitter, a battery stack and a sensor assembly.02-11-2010

Zelda Goodman, La Jolla, CA US

Patent application numberDescriptionPublished
20110243845SOMATOSTATIN ANALOGS WITH INHIBITORY ACTIVITY TO GROWTH HORMONE RELEASE - Provided are therapeutic and diagnostic somatostatin analogs including radiotherapeutic and radiodiagnostic reagents, and methods of making and use thereof.10-06-2011