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Gong, US
Bangjian Gong, Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080249287 | Refolding Transforming Growth Factor Beta Family Proteins - Compositions and methods for folding proteins belonging to the transforming growth factor beta superfamily are disclosed. The compositions and methods allow for the folding of such proteins when produced in an expression system that does not yield a properly folded, biologically active product. | 10-09-2008 |
Baoqing Gong, Shoreline, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090099183 | PYRIMIDINES AND USES THEREOF - The invention relates to pyrimidines and uses thereof, including to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity and/or proliferation of cells such as tumor-cells. | 04-16-2009 |
| 20100189726 | LPAAT-BETA INHIBITORS AND USES THEREOF - The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity. | 07-29-2010 |
Caiguo Gong, Pearland, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20080214707 | Nanocomposite Comprising Stabilization Functionalized Thermoplastic Polyolefins - This invention relates to nanocomposites comprising organo-clay and at least one stabilization functionalized thermoplastic polyolefin. Preferably the stabilization functionalized thermoplastic polyolefin is represented by the formula: | 09-04-2008 |
| 20100076128 | Polyolefin Adhesive Compositions And Articles Made Therefrom - Embodiments of the present invention relate to article comprising 1) a functionalized component, 2) tackifier, and 3) an olefin polymer comprising one or more C3 to C40 olefins, optionally one or more diolefins, and less than 5 mole % of ethylene having a Dot T-Peel of 1 Newton or more, a branching index (g′) of 0.95 or less measured at the Mz of the polymer; and an Mw of 100,000 or less; where the functional component is selected from the group consisting of functionalized polymers, functionalized oligomers and beta nucleating agents; and where the Gardner color of the adhesive does not change by more than 7 Gardner units when the adhesive has been heat aged at 180° C. for 48 hours as compared to the Gardner color of the unaged composition. | 03-25-2010 |
Chen Gong, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110010600 | LDPC Hard Decision Decoder for High-Speed Wireless Data Communications - A method for low-density parity-check hard decision decoding includes computing, for every decoding iteration, a discrepancy of extrinsic messages responsive to channel inputs of a receiver, performing a flipping of the channel inputs responsive to a comparison of the discrepancy of extrinsic messages to a flipping threshold, the flipping threshold for each decoding iteration being determined based on a threshold computation responsive to a channel error probability estimation in a first iteration of a decoding of the channel inputs, and check node decoding responsive to the flipping of channel inputs | 01-13-2011 |
| 20110093760 | Message-Wise Unequal Error Protection - Message-wise unequal error protection is provided using codeword flipping to separate special and ordinary codewords without discarding any codewords. Special messages are encoded to ensure the codeword weight is less than a certain threshold weight. Ordinary messages are encoded to ensure the codeword weight is greater than the threshold weight. The bits of the codeword are flipped to enforce the weight criterion. Ordinary and special messages are encoded using different encodings to provide different levels of error protection. Upon receipt, codewords are separated into special and ordinary codewords for appropriate decoding. If a codeword is of indeterminate type, it is iteratively processed as both a special codeword and an ordinary codeword. The decoding result of each process is periodically checked to determine which decoding result satisfies decoding criteria. | 04-21-2011 |
Cuiling (sue) Gong, Plano, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100053477 | Spatial Light Modulator Sub-Pixel Architecture and Method - A semiconductor device comprises an array of individually controllable image pixels arranged in a plurality of reset groups. Each of the image pixels in the array of individually controllable image pixels has a one-to-one correspondence with at least one memory cell in an array of memory cells. The semiconductor device further comprises a plurality of sub-pixel sets, wherein each sub-pixel in the plurality of sub-pixel sets is a micromirror, and wherein each of the image pixels comprises a sub-pixel set. | 03-04-2010 |
Da-Wei Gong, Olney, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20080220417 | Novel Alanine Transaminase Enzymes and Methods of Use - Novel alanine transaminase (ALT) polypeptides and the use thereof as a diagnostic marker to predict and monitor tissue damage and/or tissue malfunction. The ALT polypeptides are murine and/or | 09-11-2008 |
| 20090280108 | SERUM AMYLOID A PROTEIN IN INFLAMMATION AND OBESITY - The present invention relates to the discovery that acute-phase serum amyloid protein A (A-SAA) is a biomarker for obesity and certain abnormal conditions. The present invention, therefore, provides methods of diagnosing obesity or an abnormal condition in a subject The present invention also provides methods of monitoring the progression of obesity or an abnormal condition in a subject. The present invention also relates to treating obesity or an abnormal condition comprising reducing the levels of active SAA1 and/or SAA2 in a subject in need thereof. | 11-12-2009 |
| 20090317393 | METHOD OF MODIFYING GLUCOSE ACTIVITY USING POLYPEPTIDES SELECTIVELY EXPRESSED IN FAT TISSUE - Isolated omentin polypeptides that selectively express in omental fat tissue and methods for the use of the polypeptides. The polypeptides can be used in a method for modifying insulin action and/or glucose metabolism in an animal. The polypeptides can be used to promote glucose uptake by animal adipocytes and other cells, tissues, and/or organs. The polypeptides can also used to provide a therapeutic treatment for diseases of or related to glucose metabolism and adipose tissues. The polypeptides are also incorporated into diagnostic tests and testing kits for diagnosing or detecting a disease or condition involving animal tissue that contains, uses, or expresses the polypeptide in an animal suspected of having the disease or condition. | 12-24-2009 |
| 20100021900 | USE OF OMENTIN 1 AND OMENTIN 2 IN THE DIAGNOSIS AND TREATMENT OF DISEASE - The present invention is directed to methods of diagnosing a disease or predicting an increased risk of a disease, such as obesity, obesity-dependent subacute inflammation, atherosclerosis, cardiovascular disease and a metabolic disease, by determining the levels of omentin 1 and 2 protein in a subject, or by determining the levels of omentin 1 and 2 gene expression in a subject. The present invention is also directed to methods of disease treatment using omentin 1 protein and omentin 2 protein. | 01-28-2010 |
Excimer Gong US
| Patent application number | Description | Published |
|---|---|---|
| 20090085600 | Method and System for Derivation of Breakdown Voltage for MOS Integrated Circuit Devices - A method and system for multi-point (e.g., double-point) GOI test that can efficiently judge failure modes by testing only two points. We can measure leakage currents at only two voltages, which are the cut points of mode A-B and B-C, instead of the whole ramped voltages to save time and cost with the same test effectiveness according to a specific embodiment. By correlating leakage current at extrinsic field to the breakdown voltage, we can also evaluate the intrinsic reliability even if the samples are not subjected to actual breakdown according to a specific embodiment. | 04-02-2009 |
Frank Gong, Syosset, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100081309 | SEALED, SOLDERLESS I/O CONNECTOR - A sealed, solderless I/O connector for allowing the connection of cables or desk accessories to a mobile communication device while providing a weather tight seal allowing the use of the mobile communication device outdoors. The sealed, solderless I/O connector provides for greater tolerance of mechanical stress due to vibration or dropping because the contact points between the connector and the printed circuit board accomplished with a “U” shaped spring contact. The sealed, solderless I/O connector also provides a locking mechanism to prevent unintended detachment of the cable or desk accessory. | 04-01-2010 |
| 20110049243 | HANDLE AND ACTIVATION ASSEMBLY FOR PORTABLE ELECTRONIC DEVICE - A scanning assembly is disclosed. The scanning assembly comprises a mobile electronic device comprising an optical sensor, the mobile electronic device adapted to perform a scanning operation, and a trigger assembly. The trigger assembly comprises a handle member adapted to be releasably coupled to the mobile electronic device, the handle member comprising a light source, and a switch assembly adapted to receive input from an operator of the trigger assembly, wherein the light source is adapted to emit a light signal in response to manipulation of the switch assembly, and wherein the mobile electronic device is adapted to perform the scanning operation in response to receiving the light signal with the optical sensor. | 03-03-2011 |
Gangli Gong, Little Neck, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110071124 | Compounds that Inhibit Production of sAPPB and AB and Uses Thereof - The present invention relates to compounds with activity as inhibitors of sAPPβ and Aβ production, and methods for treating, preventing, or ameliorating neurodegenerative diseases, such as Alzheimer's disease and pharmaceutical compositions containing such candidate compounds. | 03-24-2011 |
| 20120064099 | COMPOUNDS THAT INHIBIT NFKB AND BACE1 ACTIVITY - The present invention relates to compounds with activity as BACE1 and NFκB modulators, and methods for treating, preventing, or ameliorating neurodegenerative diseases, such as Alzheimer's disease. The present invention is also directed to the treatment of diseases related to dysfunction of cell proliferation, the immune system and/or inflammation using such compounds or pharmaceutical compositions containing such candidate compounds. | 03-15-2012 |
Gangli Gong, Elmhurst, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120029022 | Potent Non-Urea Inhibitors Of Soluble Epoxide Hydrolase - The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension. | 02-02-2012 |
Hua Gong, King Of Prussia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090075995 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF - Novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity, including inflammatory and immune diseases, having the structure of formula (I): | 03-19-2009 |
Huiling Gong, Nashua, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20090063516 | Load on demand network analysis - Systems, methodologies, media, and other embodiments associated with load on demand network analysis are described. One method embodiment includes accessing a network analysis request and data associated with a set of network partitions associated with a network. The request describes a function to be performed on the network. A set of partitions subdivides the network and a data model stores data describing the network and its partitions. Thus, the example method may include identifying a member of the set of network partitions associated with the network analysis request and selectively loading data associated that member. The method may then perform the network analysis function on the data associated with the member rather than on data describing the entire network. | 03-05-2009 |
| 20110170428 | NETWORK BUFFER - Systems, methods, and other embodiments associated with generating a network buffer are provided. A network data model is input that includes a set of network elements, such as nodes and links, and respective costs associated with respective network elements. A center network element around which to generate the network buffer and an offset cost to define a boundary of the network buffer are also input. A network buffer is generated by determining a buffer coverage and cost. The network buffer is made up of a set of buffer network elements located within the offset cost with respect to the center network element. The cost for each buffer network element is determined as the cost associated with travelling a path with minimum cost from the center network element to the corresponding buffer network element. The buffer coverage and costs are output for subsequent analysis. | 07-14-2011 |
Jianlin Gong, Wayland, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100247562 | Complexes Derived from Heterohybrid Cells and Uses Thereof - The present invention relates, generally, to pharmaceutical compositions comprising Heat Shock Proteins (HSPs) and HSP complexes recovered from heterohybrid cells that are generated from the fusion of a first type of cell (Type I) with a second type of cell (Type II). In further embodiments, the present invention relates to preparing HSPs and/or HSP complexes recovered from heterohybrid, and to methods to treat and/or prevent diseases, such as cancer and infectious diseases by administering a pharmaceutical composition comprising a HSP and/or HSP complex recovered from heterohybrid cells that are generated from the fusion of a first type of cell (Type I) with a second type of cell (Type II). | 09-30-2010 |
Jie Gong, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20120111115 | Non-Contact Microelectronic Device Inspection Systems And Methods - Non-contact microelectronic device inspection systems and methods are discussed and provided. Some embodiments include a method of generating a virtual reference device (or chip). This approach uses a statistics to find devices in a sample set that are most similar and then averages their time domain signals to generate the virtual reference. Signals associated with the virtual reference can then be correlated with time domain signals obtained from the packages under inspection to obtain a quality signature. Defective and non-defective devices are separated by estimating a beta distribution that fits a quality signature histogram of inspected packages and determining a cutoff threshold for an acceptable quality signature. Other aspects, features, and embodiments are also claimed and described. | 05-10-2012 |
Jie Gong, Eden Prairie, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20090279206 | FABRICATION OF TRAPEZOIDAL POLE FOR MAGNETIC RECORDING - A method for forming a magnetic write pole with a trapezoidal cross-section is described. The method consists of first forming a magnetic seedlayer on a base followed by depositing a removable material layer on the seedlayer, and then a resist layer on the removable material layer. A trench is then formed in the resist, and the resist is heated to cause the cross-sectional profile of the trench to assume a trapezoidal shape. The resist is then capped with another resist layer and further heated to cause the width of the trapezoidal trench to become narrower. The cap layer and removable material layer at the bottom of the trench are then removed and the trench filled with magnetic material by electroplating. The resist and seedlayer external to the trench are finally removed to form a write pole with a trapezoidal cross-section. | 11-12-2009 |
| 20100247960 | PATTERNED ECC AND GRADIENT ANISOTROPY MEDIA THROUGH ELECTRODEPOSITION - An electrodeposited magnetic recording medium having multiple coercivity values is disclosed. In some embodiments, layers having different coercivity levels may be separated by exchange coupled composites and in other embodiments a range of coercivity levels are deposited in a gradient fashion. In some embodiments, the layers with multiple coercivity values comprise bit patterned media islands formed from a photoresist. | 09-30-2010 |
| 20100273026 | Patterned Magnetic Recording Media By Selective Anodic Removal Of An Element - A patterned magnetic recording media and method thereof is provided. A recording layer comprises a continuous surface of more-noble elements and less-noble elements, such as CoXYZ, wherein X can be Pt, Pd, Ru, Rh, Ir, Os, or Au, wherein Y can be null or Cr, and wherein Z can be null, Cu, Ta, Ti, O, B, Ag, or TiO | 10-28-2010 |
| 20110171425 | FORMATION OF PATTERNED MEDIA BY SELECTIVE ANODIC REMOVAL FOLLOWED BY TARGETED TRENCH BACKFILL - A method is disclosed for defining discrete magnetic and non-magnetic regions on the magnetic film layer of a storage media substrate. The method applies anodic oxidation of a cobalt-containing magnetic film layer to remove cobalt, followed by controlled deposition of a non-magnetic matrix into the regions where the cobalt has been removed. Deposition may either be electrodeposition, collimated vacuum deposition, or other methods depending upon the composition of the non-magnetic matrix being deposited. The method may be performed in a single electrochemical cell. | 07-14-2011 |
Jie Gong, Pittsburgh, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090073858 | HAMR Recording Head Having A Sloped Wall Pole - An apparatus includes a waveguide having an end adjacent to an air bearing surface, first and second poles positioned on opposite sides of the waveguide, and wherein the first pole includes a first portion spaced from the waveguide and a second portion extending from the first portion to the air bearing surface, with the second portion being structured such that an end of the second portion is closer to the waveguide than the first portion. | 03-19-2009 |
Jing Gong, Manvel, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100104511 | METHODS AND COMPOSITIONS USING CHELATOR-ANTIBODY CONJUGATES - Disclosed are pharmaceutical compositions that include a chelator and an antibody directed against a phosphorylation site of a protein, wherein the antibody is conjugated to the chelator to form a chelator-antibody conjugate. For example, the antibody may recognize a phosphorylated tyrosine residue or a phosphorylated serine residue of a cell surface receptor. Also disclosed are methods of synthesizing a radiolabeled chelator-antibody conjugate, wherein the antibody is directed against a phosphorylation site of a protein. Also disclosed are methods for imaging a site in a subject that involve administering to the subject an effective amount of a composition that includes a valent metal ion-labeled chelator-antibody conjugate, wherein the antibody is an antibody directed against a phosphorylation site of a protein, and detecting a radioactive signal from the site in the subject following administration of an effective amount of the composition. The method of imaging can be applied in diagnosing a tumor, such as a tumor that can be responsive to therapy using a tyrosine kinase inhibitor, and in the treatment of a tumor, such as by targeting therapy to cell surface receptors that include phosphorylation sites. | 04-29-2010 |
Jiong Gong, Lafayette, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20090161752 | METHOD AND SYSTEM OF PROVIDING SWITCH BROADCAST TELEVISION - A method and system of providing switched broadcasting of content to a number of consumers. The content may be transmitted in pieces over broadcast and switched transmission tiers. The broadcast tier being characterized by the continuous transmission of content and the switched tier being characterized by on demand or request based transmission of content. | 06-25-2009 |
| 20090165064 | System for Updating Channel Lineup for Broadcasting and Switched Digital Broadcasting Services - In a system that is capable of operating in a broadcast mode and a switched mode, it is advantageous to be able to shift program delivery between the two modes. Thus when one video program is being delivered to at least a first customer in a first mode, this program may be delivered to at least a second customer in a second mode that is different from the first mode. In this manner, the video program that is being delivered to first customer will be maintained in the original mode while new requests for this program will be served in a different mode until the delivery of the program to the first customer has been completed. In other words, legacy program delivery is maintained until the program delivery has been completed or otherwise terminated, while delivery of the program in response to new requests for the same program will be delivered in a different mode instead. | 06-25-2009 |
Kening Gong, Bartlesville, OK US
| Patent application number | Description | Published |
|---|---|---|
| 20120108860 | PROCESS FOR PRODUCING HIGH QUALITY PYROLYSIS OIL FROM BIOMASS - This invention relates to a process to utilize a torrefaction pretreatment step for biomass pyrolysis process. This pretreatment improves the quality of the pyrolysis oil by reducing acidity. The inventive process shows that as a pretreatment to pyrolysis, resulting pyrolysis oil obtained from torrefied biomass has approximately 25% lower acetic acid than that from untorrefied biomass pyrolysis oil. | 05-03-2012 |
| 20120116135 | HEAT INTEGRATED PROCESS FOR PRODUCING HIGH QUALITY PYROLYSIS OIL FROM BIOMASS - This invention discloses a heat integrated and energy saving process for producing high quality pyrolysis oil from biomass by utilizing a torrefaction pretreatment step for biomass pyrolysis processing wherein the pretreatment step improves the quality of the pyrolysis oil by reducing acidity. This invention further utilizes the gaseous product of the torrefaction step through a combustion process for heat production and recovery. | 05-10-2012 |
Kitty L. Gong, Macomb, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20120076960 | EMBLEM ASSEMBLY AND METHOD OF FORMING SAME - An emblem assembly configured for attachment to a vehicle includes a first element and a second element. The first element is configured for attachment to the vehicle and has a first surface and a second surface recessed from the first surface. The second element is configured for attachment to the first element and has a third surface, a fourth surface spaced apart from the third surface, and a fifth surface extending between the third and fourth surfaces, wherein the fifth surface is spaced apart from the second surface to define a channel therebetween. The assembly includes a first coating disposed on the third surface and a tape disposed in contact with at least a portion of each of the second surface, the first coating, and the fifth surface to thereby fill at least a portion of the channel. A method of forming the assembly is also disclosed. | 03-29-2012 |
Leon Gong, Austin, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090292743 | MODELING USER ACCESS TO COMPUTER RESOURCES - Embodiments of the invention provide a method for detecting changes in behavior of authorized users of computer resources and reporting the detected changes to the relevant individuals. The method includes evaluating actions performed by each user against user behavioral models and business rules. As a result of the analysis, a subset of users may be identified and reported as having unusual or suspicious behavior. In response, the management may provide feedback indicating that the user behavior is due to the normal expected business needs or that the behavior warrants further review. The management feedback is available for use by machine learning algorithms to improve the analysis of user actions over time. Consequently, investigation of user actions regarding computer resources is facilitated and data loss is prevented more efficiently relative to the prior art approaches with only minimal disruption to the ongoing business processes. | 11-26-2009 |
| 20090293121 | DEVIATION DETECTION OF USAGE PATTERNS OF COMPUTER RESOURCES - Embodiments of the invention provide a method for detecting changes in behavior of authorized users of computer resources and reporting the detected changes to the relevant individuals. The method includes evaluating actions performed by each user against user behavioral models and business rules. As a result of the analysis, a subset of users may be identified and reported as having unusual or suspicious behavior. In response, the management may provide feedback indicating that the user behavior is due to the normal expected business needs or that the behavior warrants further review. The management feedback is available for use by machine learning algorithms to improve the analysis of user actions over time. Consequently, investigation of user actions regarding computer resources is facilitated and data loss is prevented more efficiently relative to the prior art approaches with only minimal disruption to the ongoing business processes. | 11-26-2009 |
Ling Gong, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20120103244 | Truss Cable Semi-submersible Floater for Offshore Wind Turbines and Construction Methods - Truss cable semi-submersible floater for offshore wind turbines and construction methods are provided. A floating system includes a hull, a tensioned cable system, and a tower. The hull includes vertical buoyant columns with one column at the center of the pattern, larger size column base tanks, and a truss system, all of which are coupled to each other for supporting the tower and wind turbines. The column can be made of hybrid materials, including steel and composite-concrete. The steel section and the composite-concrete section of the column can be connected by grouting. The tensioned cable system including upper, lower, and diagonal tensioned cables to connect the column, the column base, and the tower to reduce the bending moments and improve stability, strength and dynamic performance of the hull structure. | 05-03-2012 |
Lixin Gong, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090014015 | INTRAOPERATIVE DOSIMETRY FOR PROSTATE BRACHYTHERAPY USING TRANSRECTAL ULTRASOUND AND X-RAY FLUOROSCOPY - While performing prostate brachytherapy in which radioactive seeds are implanted into the prostate, both X-ray and transrectal ultrasound (TRUS) data are collected. The X-ray data indicate all of the implanted seeds, but not their relative position within the prostate. The TRUS data correspond to both axial and longitudinal ultrasound images. A subset of the implanted seeds can be automatically (or manually) detected in the TRUS data (using longitudinal ultrasound images), and the prostate is indicated in the TRUS data (using axial ultrasound images). Registration is performed between the X-ray and TRUS data, thereby identifying the disposition of all implanted seeds within the prostate, enabling dosimetry to be intraoperatively determined. A medical practitioner can thus determine whether and where to implant additional seeds to achieve a desired optimal dosage and do so before the prostate brachytherapy procedure is concluded. | 01-15-2009 |
Ming Gong, Katy, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20120132437 | Plunger Lift Systems and Methods - The present invention discloses apparatuses, systems, and methods for operating a gas well. Some embodiments include a plunger apparatus configured to fall through a continuous water phase (including water slugs) in a gas producing well by overcoming pressure and drag 5 forces from the water by having a sufficient mass, hydrodynamic profile, and sufficiently large area for passage of the continuous water. In one embodiment, a plunger body and plug mechanism are provided, wherein the plug mechanism has open and closed positions, which may be automatically changed or controlled by a surface or other control system, and wherein the plunger body and plug may be a physically integrated one-piece system, or an interoperable two piece system. | 05-31-2012 |
Ping Gong, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100187133 | CAPACITIVE MORPHOLINO DIAGNOSTICS FOR ANALYSIS OF NUCLEIC ACIDS - Surface hybridization, a reaction in which nucleic acid molecules in solution react with nucleic acid partners immobilized on a surface, is widely practiced in life science research. In these applications the immobilized partner, or “probe”, is typically single-stranded DNA. Because DNA is strongly charged, high salt conditions are required to enable binding between analyte nucleic acids (“targets”) in solution and the DNA probes. High salt, however, compromises prospects for label-free monitoring or control of the hybridization reaction through surface electric fields, as well as stabilizes secondary structure in target species that can interfere with probe-target recognition. In this work, initial steps toward addressing these challenges are taken by introducing Morpholinos, a class of uncharged DNA analogues, for surface-hybridization applications. Monolayers of Morpholino probes on gold supports can be fabricated with methods similar to those employed with DNA, and are shown to hybridize efficiently and sequence-specifically with target strands. Hybridization-induced changes in the interfacial charge organization are analyzed with electrochemical methods and compared for Morpholino and DNA probe monolayers. Molecular mechanisms connecting surface hybridization state to the interfacial capacitance are identified and interpreted through comparison to numerical Poisson-Boltzmann calculations. Interestingly, positive as well as negative capacitive responses (contrast inversion) to hybridization are possible, depending on surface populations of mobile ions as controlled by the applied potential. Quantitative comparison of surface capacitance with target coverage (targets/area) reveals a near-linear relationship, and demonstrates sensitivities (limits of quantification) in the pg mm | 07-29-2010 |
Ping Gong, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100035248 | SURFACE-BASED NUCLEIC ACID ASSAYS EMPLOYING MORPHOLINOS - The sequence determination, detection, and quantification of nucleic acid molecules through sequence-specific binding (hybridization) on a solid support, specifically when Morpholinos are used as the surface-immobilized probe species in surface-based nucleic acid assays, and the assays as disclosed herein. | 02-11-2010 |
Ping Gong, Melrose, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120010529 | SAMPLING DEVICES AND METHODS INVOLVING RELATIVELY LITTLE PAIN - The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood, from subjects, e.g., to the skin and/or from the skin. In one aspect, the present invention is generally directed to devices and methods for receiving blood from a subject, e.g., from the skin, using devices including a substance transfer component (which may contain, for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In certain embodiments, substances may be received from and/or delivered to the subject with relatively little pain. The pain may be assessed, to for example, using pain scales such as the Wong-Baker FACES Pain Scale. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to receive blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be received from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for receiving blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like. | 01-12-2012 |
Ping Gong, Elmhurst, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100300899 | Active CMOS Sensor Array For Electrochemical Biomolecular Detection - Electrochemical sensing of biomolecules eliminates the need for bulky optical instruments required in traditional fluorescence-based sensing assays. Integration of the sensor interface electrodes and active electrochemical detection circuitry on CMOS substrates miniaturizes the sensing platform, enhancing portability for point-of-care applications, while enabling high-throughput, highly-parallel analysis. One embodiment includes a four-by-four active sensor array for multiplexed electrochemical biomolecular detection in a standard 0.25-μm CMOS process. Integrated potentiostats, including control amplifiers and dual-slope ADCs, stimulate the electrochemical cell and detect the current flowing through on-chip gold electrodes at each sensor site resulting from biomolecular reactions occurring on the chip surface. Post-processing techniques for fabricating biologically-compatible surface-electrode arrays in CMOS that can withstand operation in harsh electrochemical environments are described. Demonstrations showing example operation of the active CMOS array for biomolecular detection include cyclic voltammetry of a reversible redox species, DNA probe density characterization, and quantitative and specific DNA hybridization detection in real time. | 12-02-2010 |
Qing Gong US
| Patent application number | Description | Published |
|---|---|---|
| 20110280761 | AMORPHOUS ALLOYS HAVING ZIRCONIUM AND METHODS THEREOF - Alloys and methods of preparing the same are provided. The alloys are represented by the general formula of (Zr | 11-17-2011 |
| 20120045658 | METALIZED PLASTIC ARTICLES AND METHODS THEREOF - Metalized plastic substrates, and methods thereof are provided herein. The method includes providing a plastic substrate having a plurality of accelerators dispersed in the plastic substrate. The accelerators have a formula selected from the group consisting of: CuFe | 02-23-2012 |
Wangsong Gong, Revere, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120000474 | VESTIBULAR CANAL PLUG - An apparatus to reduce the sensitivity of the vestibular system to stimulation. The apparatus comprises a plugging device configured to constrain the movement of endolymph fluid within a semicircular canal, and a control module coupled to the plugging device that causes the plugging device to maintain a set actuated position. | 01-05-2012 |
| 20120123383 | VESTIBULAR STIMULATOR - A method for providing relief from Meniere's disease, includes reversibly disabling vestibular function following detection of an attack of Meniere's disease following detection of an attack of Meniere's disease. | 05-17-2012 |
Weibo Gong, Amherst, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090138715 | WIRELESS NETWORK SECURITY USING RANDOMNESS - The present invention provides systems and methods for securing communications in a wireless network by utilizing the inherent randomness of propagation errors to enable legitimate users to dynamically create a shared symmetric secret key. In one embodiment, the invention provides a system with two computers each having a wireless network adapter. The sending node encodes the frames, transmits the frames, determines if the frames were correctly received, retransmits the frames if they were not correctly received, stores the frames that were not retransmitted, and applies a uses the stored frames to generate a secret key. The receiving node receives the encoded frames, determines if the frames were retransmitted, stores at least one of the frames that was not retransmitted, and uses the stored frames to generate the same secret key as the receiving node. | 05-28-2009 |
Weiliang Gong, Rockville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110052921 | REACTIVITY OF FLY ASH IN STRONGLY AKLALINE SOLUTION - Provided in one embodiment is a method of charactering a fly ash composition, comprising determining a reactivity of the fly ash composition in a solution. The applicability of the findings to low water-to-solid ratios for the process of geopolymerization for the relationship between the amounts of fly ash reacted, and the compressive strength of a geopolymer cement is also described. | 03-03-2011 |
| 20110104792 | LOW-TEMPERATURE SOLIDIFICATION OF RADIOACTIVE AND HAZARDOUS WASTES - Treatment of a radioactive waste stream is provided by adding sodium hydroxide (NaOH) and/or potassium hydroxide (KOH) together with a rapidly dissolving form of silica, e.g., fumed silica or fly ash. Alternatively, the fumed silica can be first dissolved in a NaOH/KOH solution, which is then combined with the waste solution. Adding a binder that can be a mixture of metakaolin (Al | 05-05-2011 |
| 20120024196 | TAILORED GEOPOLYMER COMPOSITE BINDERS FOR CEMENT AND CONCRETE APPLICATIONS - A geopolymer composite binder is provided herein, the composite binder including (i) at least one fly ash material having less than or equal to 15 wt % of calcium oxide; (ii) at least one gelation enhancer; and (iii) at least one hardening enhancer having a different composition from a composition of the at least one fly ash material. | 02-02-2012 |
Weiyan Gong, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20110254533 | Coaxial Illumination Of Coulter Aperture In Full Function Hematology Analyzer - A method for directly illuminating a Coulter aperture so light scattering can be incorporated into the classical Coulter aperture and 3-diff blood analyzer to realize full functional hematology analyzer by providing a flow chamber which is separated into two portions by a plate having a Coulter aperture; and using a light source to directly coaxial illuminate the Coulter aperture wherein the illuminating beam propagates in the same direction as the axis of the Coulter aperture and the cell's moving direction. | 10-20-2011 |
Xiaoda Gong, Audubon, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100332469 | SYSTEMS AND METHODS FOR ACCESSING DATA FROM A DATABASE - Systems and methods for accessing data from a database are provided. A user selection of a database object may be received. One or more input fields for obtaining user input associated with the selected database object may be dynamically generated and presented to the user. User input associated with the selected database object may be received via the one or more generated input fields. A database query may then be generated utilizing the received user input, and the database may be queried utilizing the constructed database query. | 12-30-2010 |
Xiaolong Gong, West Bloomfield, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110155484 | VEHICLE - The present invention pertains to a lightweight, portable, electric vehicle having a novel steering mechanism, a low profile suspension and drive mechanism, and which also provides a superior ride quality, handling, and drivability. The vehicle generally comprises a frame and at least one suspension and motor assembly. Each suspension and motor assembly includes at least one leaf spring mounted to the frame, a motor connected to the leaf spring, the motor having a drive shaft, and a wheel rotatably connected to the drive shaft. The vehicle also includes means for powering the motor and means for controlling to enable a user to drive the vehicle. | 06-30-2011 |
Xiaoyi Gong, Bartlesville, OK US
| Patent application number | Description | Published |
|---|---|---|
| 20100051558 | NAPHTHENIC ACID REMOVAL PROCESS - A process is disclosed for removing naphthenic acid from a waste water stream using a composition containing a zeolite and carbon, wherein the carbon is present on the exterior surfaces and pore surfaces of the zeolite, for removal of at least a portion of the naphthenic acid from the waste water stream resulting in a treated water stream comprising less naphthenic acid than the waste water stream. | 03-04-2010 |
| 20100155262 | APPARATUS AND METHOD TO MEASURE ELECTROCHEMICAL IMPEDANCE - An electrochemical cell apparatus and method comprising a first electrode and a second electrode wherein the area ratio between them is 15 or higher, for example a metal plate and a metal wire; wherein said first and second electrodes are made from the same material; and wherein the distance between said first electrode and said second electrode is in the range of from about 1 mm to about 1 μm is provided. Such electrochemical cell can be used to measure crude oil corrosion using an electrochemical impedance method. | 06-24-2010 |
| 20100300937 | NAPHTHENIC ACID REMOVAL AND CONVERSION - Methods and apparatus relate to handling of organic contaminants in aqueous streams. The methods and apparatus enable removing the contaminants, such as naphthenic acids, from the aqueous streams and then converting the contaminants into hydrocarbons. The removing and converting of the organic contaminates results in treated discharge and generation of the hydrocarbons, which add to amount of hydrocarbon recovery. | 12-02-2010 |
Xiaoyi Gong, Ponca City, OK US
| Patent application number | Description | Published |
|---|---|---|
| 20080199749 | ORGANIC ANODES FOR HYDROCARBON FUEL CELLS - Novel anodes for hydrocarbon fuel cells are described herein. Embodiments of the anode incorporate free radical initiators to facilitate the electro-chemical reaction kinetics at the anode in hydrocarbon fuel cells. In an embodiment, an anode for a hydrocarbon fuel cell comprises an electrically conductive substrate. The anode further comprises a layer comprising a free radical initiator. The layer is applied to the electrically conductive substrate. In addition, methods of making the anodes are disclosed. | 08-21-2008 |
| 20090020735 | FLAME RETARDANT COMPOSITION EMPLOYING OIL SAND TAILINGS - A flame retardant composition comprising at least one polymeric material and at least one inorganic filler, where at least a portion of the filler comprises particles derived from oil sand tailings. Such flame retardant composition can be employed in the manufacture and use of flame retardant plastics, fibers, and/or paints. | 01-22-2009 |
Xun Gong, Oviedo, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20100321191 | CERAMIC SENSORS FOR WIRELESS HIGH-TEMPERATURE SENSING - A RF resonator for sensing a physical or an environmental parameter includes a substrate having a substrate surface. A polymer-derived ceramic (PDC) element is positioned on or within the substrate surface. The RF resonator has a resonant frequency that changes as a function of the physical or environmental parameter. A system for wirelessly sensing at least one physical or environmental parameter includes at least one RF resonator and a wireless RF reader located remotely from the RF resonator for transmitting a wide-band RF interrogation signal that excites the RF resonator. The wireless RF reader detects a sensing signal retransmitted by the RF resonator and includes a processor for determining the physical or environmental parameter at the location of the RF resonator from the sensing signal. | 12-23-2010 |
Yanfeng Gong, Pullman, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090099798 | Real-Time Power System Oscillation Detection Using Modal Analysis - A power system oscillation detection device is provided for use in an electric power system. A plurality of sample signals are acquired from the electrical power system via a plurality of intelligent electronic devices (IEDs) in communication with the power system. The power system oscillation detection device includes a real-time modal analysis module, a real-time mode identification module, and real-time decision and control logic. The real-time modal analysis module calculates modes of at least one of the signals, each mode including mode information. The real-time mode identification module together with the real-time decision and control logic determines, from the mode information, whether there is an undesirable oscillation in the electric power system and activates a remedial action. | 04-16-2009 |
| 20110264388 | FAULT LOCATION IN ELECTRIC POWER DELIVERY SYSTEMS - Accurately calculating location of a fault even on a branched, non-homogenous, radial electric power distribution system. The calculation includes determining a calculated reactance or impedance to the fault, and uses the line parameters to determine locations on the system that match the calculated reactance to the fault. The calculation may further include a determination of faulted phase and eliminate fault location possibilities based on absence of the faulted phase at those locations. The calculation may further use data reported from line monitors such as faulted circuit indicators (FCIs). | 10-27-2011 |
| 20110264389 | Fault Location in Electric Power Delivery Systems - Accurately calculating location of a phase-to-phase fault even on a branched, non-homogenous, radial electric power distribution system. The calculation includes determining a calculated reactance to the fault without using positive-sequence current measurements, and uses the line parameters to determine locations on the system that match the calculated reactance to the fault. The calculation may further include a determination of faulted phase and eliminate fault location possibilities based on absence of the faulted phase at those locations. | 10-27-2011 |
| 20120068717 | FAULT LOCATION IN A NON-HOMOGENEOUS ELECTRIC POWER LINE - Fault location on a non-homogeneous electric power line that includes a plurality of sections by determining a section in which negative-sequence voltage magnitude profiles calculated from each terminal of the power line intersect. The fault location may determine the faulted section and determine the location of the fault within the faulted section. To determine the fault location, the negative-sequence voltage magnitude profiles may be calculated from measurements taken at each terminal of the power line and compared to determine a point where the profiles intersect. The profiles may be calculated using power line properties and measurements from each terminal. | 03-22-2012 |
Ying Gong, Collierville, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20110005739 | Copper Alloy for Heat Exchanger Tube - An alloy comprising copper, nickel, tin and, optionally, phosphorus which can be used in, for example, a copper alloy tube for heat exchangers that provides excellent fracture strength and processability for reducing the weight of the tube and for use in high pressure applications with cooling media such as carbon dioxide. | 01-13-2011 |
| 20110180244 | Copper Alloys and Heat Exchanger Tubes - Alloys comprising copper, iron, tin and, optionally, phosphorus or copper, zinc, tin and, optionally, phosphorus, which can be used in, for example, a copper alloy tube for heat exchangers that provides excellent fracture strength and processability for reducing the weight of the tube and for use in high pressure applications with cooling media such as carbon dioxide. | 07-28-2011 |
Yixing Gong, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20100218124 | LOGIC FOR DESIGNING PORTLET VIEWS - A computer-implemented method, system and computer program product of designing views of portlets are presented. The computer-implemented method, which is executed on a specific processor, receives, from a client, multiple requirements for portlets and views of a portal application. Common business components are then extracted from the multiple requirements, and the business components are classified into categories of containers, data entry forms, or tables. A library of implemented common business components is created and provided to multiple developers, who are then able to design the views of the portlets, such that the portal application views will have a similar look and feel. | 08-26-2010 |
Yong Gong, Warrington, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090048295 | SUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE THEREOF - Substituted 5,6,7,8-tetrahydroquinoline derivatives, which are C5 | 02-19-2009 |
Yongping Gong, Eagan, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20100247883 | CORROSION RESISTANT COATING FOR COPPER SUBSTRATE - A protecting coating for a copper substrate is disclosed. The coating comprises seed layer comprising titanium ions that forms an “alloy-like” structure with the copper substrate. The coating further comprises a first layer of carbon disposed on the seed layer comprising titanium ions. A second layer comprising titanium is disposed on the first layer of carbon, and a second layer of carbon is disposed on the second layer comprising titanium. | 09-30-2010 |
Yuan Gong, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110111981 | METHOD FOR DETECTING ACTIVE AND LATENT VIRALLY INFECTED CELLS - The invention provides methods for detecting virus production, determining frequency and identity of HIV reservoirs, or evaluating gene expression on a single-cell basis using microengraving and RT-PCR. | 05-12-2011 |
Zhiwei Gong, Chandler, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20110244629 | Packaging Process to Create Wettable Lead Flank During Board Assembly - A method and apparatus are described for fabricating a low-pin-count chip package ( | 10-06-2011 |
| 20120021565 | METHOD OF FORMING A PACKAGED SEMICONDUCTOR DEVICE - A method is used to form a packaged semiconductor device. A semiconductor device, which has an active surface, is placed in an opening of a circuit board. The circuit board has a first major surface and a second major surface having the opening, first vias that extend between the first major surface and the second major surface, first contact pads terminating the vias at the first major surface, and second contact pads terminating the vias at the second major surface. A dielectric layer is applied over the semiconductor device and the second major surface of the circuit board. An interconnect layer is formed over the dielectric layer. The interconnect layer has second vias electrically connected to the second contact pads, third vias that are electrically connected to the active surface of the semiconductor device, an exposed surface, and third contact pads at the exposed surface. | 01-26-2012 |