Goldsmith, GB
Christopher Michael Goldsmith, Cambridge GB
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20140310414 | Methods and Apparatus for Remote Connection - A method and system for establishing a helpdesk session between a subscriber device and a customer support representative (CSR) device following a request for a helpdesk session. The system issuing, on receipt of said request, a credential pair comprising subscriber credentials for a subscriber device and CSR credentials for a CSR device which is paired with the subscriber device. The subscriber credentials are transferred to the subscriber device and the CSR credentials are transferred to the CSR device. The subscriber and CSR credentials are then transferred to a core node for authentication. If the credentials are authentic the helpdesk session between the paired subscriber device and the CSR device is established. | 10-16-2014 |
Daniel Goldsmith, Coventry GB
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20140052421 | SYSTEM AND METHOD FOR WATER DISTRIBUTION MODELLING - A method of modelling a water distribution system, the method comprising steps of: identifying a plurality of demand zones within said water distribution network; estimating water consumption data for said demand zones; simulating the hydraulic characteristics of the water distribution system using said estimated water consumption data and so; providing simulated pressure and flow rates within said demand zones; receiving output from sensors within said water distribution network in the form of pressure and flow rate data; correcting the simulated pressure and flow rate data within said demand zones based upon the sensor output and so; calibrating a model of the water distribution system. | 02-20-2014 |
Derek John Goldsmith, Edenbridge GB
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20150094291 | Method and Substance for Improving the Emotional Development of an Infant - The invention provides a method for improving the emotional development of an infant by performing controlled exposure of the infant aged less than six months old to human fear pheromone, preferably with visual fear stimuli, so that the natural synaptic connections in the brain associated with normal fear mechanisms are stimulated and exercised. This can reduce the occurrence of mental illness later in life, in particular reduce the occurrence of schizophrenia. Advantageously the exposure to fear pheromone and visual fear stimuli is terminated and followed by comforting stimuli such as feeding, physical contact, or comforting or happy visual or audible stimuli such as laughter. | 04-02-2015 |
Jake Benjamin Goldsmith, Suffolk GB
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20110040408 | ROBOTIC HAND - A robotic hand assembly comprising: a hand section comprising: at least one digit provided with at least one actuatable joint; and a control section comprising: at least one actuation device, the at least one actuation device comprising: a sensing module configured to sense a force applied to a tendon coupled at a first end to the at least one actuatable joint; and an actuation module configured to actuate the at least one actuatable joint. | 02-17-2011 |
Jake Benjamin Goldsmith, London GB
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20130313844 | ROBOTIC HAND - Aspects of the subject technology relate to a robotic finger digit including a distal finger joint coupled between a distal finger part and a middle finger part, a middle finger joint coupled between the middle finger part and a proximal finger part and an extend tendon coupled at a first end to the distal finger joint, and coupled at a second end to an actuation device. In certain aspects, the robotic finger can further include a flex tendon coupled at a first end to the distal finger joint, and coupled at a second end to the actuation device, wherein the actuation device is configured to move the extend tendon and the flex tendon substantially the same distance in order to flex and/or extend the robotic finger digit. | 11-28-2013 |
Mark Goldsmith, Leeds GB
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20140171999 | SURGICAL INSTRUMENT INSERT AND SURGICAL INSTRUMENT SYSTEM - A retaining member for a surgical instrument insert is described. The instrument insert includes a retaining member which is free to move along the shaft before the insert is attached to the handle. The retaining member comprises a resilient member integrally formed with the retaining member. The resilient member can engage the surgical instrument insert shaft and act to prevent the retaining member falling off before the insert is attached to the handle. Because the resilient member is integrally formed the cost of manufacture is reduced. In another embodiment, a surgical instrument insert is provided wherein a proximal portion of the outer shaft is manufactured from an insulating material. The insulating material can be cheaper than the aluminum conventionally used. As a further advantage this also reduces the risk of electric shock and bums when used in an electrically live environment. | 06-19-2014 |
Michael Daniel Goldsmith, Essex GB
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20110166147 | IMIDAZOPYRAZINE COMPOUNDS - Novel imidazopyrazine compounds are disclosed that have a formula represented by the following: Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a viral infection, in particular a HCV, HRV, Sb and/or CVB in a patient in need thereof. | 07-07-2011 |
Neil Goldsmith, Oxford GB
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20120094870 | Library of a Collection of Cells - The present invention relates to combinatorial gene expression libraries and methods for making these. Such libraries are useful in discovery of novel and/or enhanced metabolic pathways leading to the production of novel compounds for e.g., drug discovery and/or to the prosecution of known compounds in novel quantities or in novel compartments of the cells. The expression libraries in particular are composed of host cells capable of co-ordinated and controllable expression of large numbers of heterologous genes in the host cells. | 04-19-2012 |
Paul Goldsmith, Oxfordshire GB
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20090221659 | COMBINATION OF ALPHA-2 RECEPTOR AGONIST (CLONIDIN) AND ANTI-MUSCARINIC AGENT (OXYBUTYNIN) FOR THE TREATMENT OF SIALORRHOEA - An alpha2 adrenoreceptor agonist eg. clonidine, brimonidine, monoxidine, lofexidine is useful for the treatment of siaiorrhoea, administered by the paraungual, sublingual or buccal route. The patient to be treated is also given an anti-muscarinic agent eg. oxybutynin, glycopyrrolate, ipratropium. | 09-03-2009 |
20100184727 | TREATMENT OF EXCESS SEBUM PRODUCTION - A muscarinic receptor antagonist is useful for the treatment or prevention of a condition associated with excess sebum production or excretion. | 07-22-2010 |
Paul Goldsmith, Oxon GB
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20100298282 | Treatment of Ocular Conditions and the Side-Effects of Glucocorticoids - A compound having glucocorticoid receptor (GR) antagonist activity and a clogP value of less than 5 is useful for the treatment of an ocular condition. Further, a compound having glucocorticoid receptor (GR) antagonist activity is useful, for the treatment of a patient exhibiting side-effects of the administration of a glucocorticosteroid, e.g. wherein the glucocorticosteroid and said compound are administered by different routes. | 11-25-2010 |
Paul Goldsmith, Berkshire GB
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20090209559 | PHARMACEUTICAL COMPOUNDS - Fused pyrimidines of formula (I): | 08-20-2009 |
Paul Goldsmith, Slough Berkshire GB
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20110230464 | PURINE DERIVATIVES USEFUL AS P13 KINASE INHIBITORS - This invention provides a compound which is a purine of formula (Ia) or (Ib): and the pharmaceutically acceptable salts thereof that are inhibitors of PI3K and a selective for the p110δ isoform, which is a class Ia PI3 kinase, over other class Ia PI3 kinases and over class Ib kinases. The compounds may be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders. | 09-22-2011 |
Paul Goldsmith, Abingdon GB
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20120316213 | COMBINATION OF ALPHA-2 RECEPTOR AGONIST (CLONIDIN) AND ANTI-MUSCARINIC AGENT (OXYBUTYNIN) FOR THE TREATMENT OF SIALORRHOEA - An alpha2 adrenoreceptor agonist eg. clonidine, brimonidine, monoxidine, lofexidine is useful for the treatment of siaiorrhoea, administered by the paraungual, sublingual or buccal route. The patient to be treated is also given an anti-muscarinic agent eg. oxybutynin, glycopyrrolate, ipratropium. | 12-13-2012 |
Paul John Goldsmith, Berkshire GB
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20100016306 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITORS - Thienopyrimidines of formula (Ia) or (Ib): | 01-21-2010 |
20100130496 | PYRIMIDINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE - The invention provides a pyrimidine compound of formula (I): | 05-27-2010 |
20100210646 | 2-MORPHOLIN-4-YL-PYRIMIDINES AS PI3K INHIBITORS - The invention provides a pyrimidine compound of formula (I): | 08-19-2010 |
Paul John Goldsmith, Slough GB
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20120283257 | PHARMACEUTICAL COMPOUNDS - Thienopyrimidines of formula (Ia) or (Ib): | 11-08-2012 |