| Patent application number | Description | Published |
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| 20090061457 | Apolipoprotein E3 protein as a biomarker of Parkinson's disease - The present invention relates to an Apolipoprotein E3 protein as a biomarker for neurodegenerative disease, including Parkinson's disease, and the related diseases. More specifically, the present invention relates to the identification of an Apolipoprotein E3 protein, useful for the screening, diagnosis, and differentiation of Parkinson's disease from Alzheimer's disease, other neurodegenerative diseases, and normal controls. | 03-05-2009 |
| 20090275046 | Complement factor H protein as a biomarker of Parkinson's disease - The present invention relates to a Complement Factor H protein as a biomarker for neurodegenerative disease, including Parkinson's disease, and the related diseases. More specifically, the present invention relates to the identification of a Complement Factor H protein, useful for the screening, diagnosis, and differentiation between neurodegenerative diseases. | 11-05-2009 |
| 20100004871 | Identities, specificities, and use of twenty two (22) differentially expressed protein biomarkers for blood based diagnosis of breast cancer - The present invention discloses twenty two 22 protein biomarkers of breast cancer. More specifically, the present invention discloses the identities, specificities, and uses of up to twenty two (22) protein biomarkers in blood serum for distinguishing between patients with earlier and later stages of breast cancer, patients with benign breast diseases or abnormalities, and normal individuals lacking breast abnormalities. | 01-07-2010 |
| 20100129846 | Isoform specificities of blood serum proteins and their use as differentially expressed protein biomarkers for diagnosis of breast cancer - The present invention discloses twenty two 22 protein biomarkers of breast cancer. More specifically, the present invention discloses the identities, specificities, and uses of up to twenty two (22) protein biomarkers in blood serum for distinguishing between patients with earlier and later stages of breast cancer, patients with benign breast diseases or abnormalities, and normal individuals lacking breast abnormalities. More specifically, the present invention relates to specificities of isoforms of up to 22 protein biomarkers in blood serum for distinguishing between patients with earlier and later stages of breast cancer, patients with benign breast diseases or abnormalities, and normal individuals lacking breast abnormalities. | 05-27-2010 |
| 20100167937 | Multiple forms of Alzheimer's disease based on differences in concentrations of protein biomarkers in blood serum - The present invention relates to identification and uses of biomarkers for neurodegenerative disease, including Alzheimer's disease, and the related diseases. More specifically, the present invention relates to the identification of protein biomarkers useful for the screening, diagnosis, and differentiation of Alzheimer's disease from Parkinson's disease, other neurodegenerative diseases, and normal controls, and in the monitoring of Alzheimer's disease severity and disease mechanisms in patients. | 07-01-2010 |
| Patent application number | Description | Published |
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| 20080289964 | Assays for diagnosis and therapeutics employing similarities and differences in blood serum concentrations of 3 forms of complement C3c and related protein biomarkers between amyotrophic lateral sclerosis and Parkinson's disease - The invention relates to assays for diagnosis, drug targeting and therapeutic response monitoring, of patients with Parkinson's disease (PD), with PD-Like disorders that express symptoms like PD, age-matched controls (Normal), Patients with Amyotrophic Lateral Sclerosis (ALS), with ALS-Like disorders that express symptoms like ALS, and age-matched controls (Normal). The method is based on the use of 2-dimensional (2D) gel electrophoresis to separate the complex mixture of proteins found in blood serum, the quantitation of a group of identified biomarkers, and the biostatistical analysis of the concentration of the identified biomarkers. | 11-27-2008 |
| 20090035801 | Twelve (12) protein biomarkers for diagnosis and early detection of breast cancer - The invention relates to 12 identified protein biomarkers for diagnosis, determination of disease severity, and therapeutic response monitoring of patients with breast cancer. The method is based on the use of 2-dimensional (2D) gel electrophoresis to separate the complex mixture of proteins found in blood serum, the quantitation of up to 12 protein biomarkers, and statistical analysis of the concentration of the protein biomarkers. | 02-05-2009 |
| 20100294664 | Assay for ALS and ALS-like disorders - The invention relates to an assay for discriminating between amyotrophic lateral sclerosis (ALS) patients and patients with ALS-like disorders that express symptoms like ALS. The method is based on the use of 2-dimensional (2D) gel electrophoresis to separate the complex mixture of proteins found in blood serum, the quantitation of a group of identified biomarkers, and the biostatistical analysis of the concentration of the identified biomarkers to differentiate patients having ALS from patients having other ALS-like disorders. | 11-25-2010 |
| 20100314251 | Diagnosis of Parkinson's disease - A method of diagnosing Parkinson's disease uses the abnormal concentrations of a group of 21 blood serum protein biomarkers. The concentration of the 21 protein biomarkers is assessed in a patient's serum by quantitative two-dimensional polyacrylamide gel electrophoresis. | 12-16-2010 |
