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Goldin, US

Alexander D. Goldin, Glenview, IL US

Patent application numberDescriptionPublished
20100055046COMPOSITION AND METHOD FOR TREATING COLDS - Viral upper respiratory tract infections, upper respiratory infections, and common colds can be effectively treated by the administration of a combination of a nasal steroid and a nasal antihistamine. By the administration of the combination of a nasal steroid and a nasal antihistamine with the onset of cold symptoms, the histamine cascade and the inflammatory response are impeded or eliminated, reducing the severity, duration, or frequency of the onset of cold symptoms. The combination of a nasal steroid and a nasal antihistamine may be, for example, a physical mixture of the steroid and antihistamine, or it may effectively be a combination wherein the patient is administered one component (either the steroid or the antihistamine) followed by the other, without physical mixing beforehand.03-04-2010

Barry R. Goldin, West Newton, MA US

Patent application numberDescriptionPublished
20110274722FOOD CONTAINING A PROBIOTIC AND AN ISOLATED BETA-GLUCAN AND METHODS OF USE THEREOF - The invention features a food product containing a probiotic and β-glucan isolated from a natural source, methods of treating a disease or disorder by administering the food product, and a package containing separated components of the food product.11-10-2011

Ehud Goldin, Rockville, MD US

Patent application numberDescriptionPublished
20100086481DIFFERENTIAL EXPRESSION OF MOLECULES ASSOCIATED WITH INTRA-CEREBRAL HEMORRHAGE - Methods are provided for evaluating a stroke, for example for determining whether a subject has had a hemorrhagic stroke, determining the severity or likely neurological recovery of a subject who has had a hemorrhagic stroke, and determining a treatment regimen for a subject who has had a hemorrhagic stroke, as are arrays and kits that can be used to practice the methods. In particular examples, the method includes screening for expression of hemorrhagic stroke related genes (or proteins), such as genes (or proteins) involved in suppression of the immune response, genes (or proteins) involved in vascular repair, genes (or proteins) involved in the acute inflammatory response, genes (or proteins) involved in cell adhesion, genes (or proteins) involved in hypoxia, genes (or proteins) involved in signal transduction, and genes (or proteins) involved in the response to the altered cerebral microenvironment. Arrays and kits are provided that can be used in the disclosed methods. Also provided are methods of identifying one or more agents that alter the activity (such as the expression) of a hemorrhagic stroke-related molecule.04-08-2010
20100267582DIFFERENTIAL EXPRESSION OF MOLECULES ASSOCIATED WITH ACUTE STROKE - Methods are provided for evaluating a stroke, for example for determining whether a subject has had an ischemic stroke, determining the severity or likely neurological recovery of a subject who has had an ischemic stroke, and determining a treatment regimen for a subject who has had an ischemic stroke, as are arrays and kits that can be used to practice the methods. In particular examples, the method includes screening for expression in ischemic stroke related genes (or proteins), such as white blood cell activation and differentiation genes (or proteins), genes (or proteins) related to hypoxia, genes (or proteins) involved in vascular repair, and genes (or proteins) related to a specific peripheral blood mononuclear cell (PBMC) response to the altered cerebral microenvironment. Also provided are methods of identifying one or more agents that alter the activity (such as the expression) of an ischemic stroke-related molecule.10-21-2010

Iliya Goldin, Rochester, MI US

Patent application numberDescriptionPublished
20100031913MODULAR INTAKE MANIFOLD - Disclosed herein is an intake manifold assembly that comprises a first outer covering, a second outer covering connected to the first outer covering that together define a chamber having an intake port, and a flow channel insert. The second outer covering has an outlet port positioned within its interior surface and the flow channel insert is nestingly connected to the outlet port with the rest of the flow channel insert received within the chamber. The flow channel insert being a single piece that defines a channel having a first end and a second end.02-11-2010
20100059009ASSEMBLY AND METHOD FOR CONTROLLING AN AIR INTAKE RUNNER - An assembly for controlling an air intake runner of an air intake manifold. The assembly includes a cartridge including a plurality of compartments. Each of the compartments has a plurality of that are joined to define a central opening and an outer perimeter. Adjacent compartments are spaced apart to define a groove between each of the compartments. The assembly also includes bushing carriers that are configured to be snap-fit into one of the grooves of the cartridge. The assembly further includes bushings configured to rotatably fit within the central openings of the bushing carriers. Each of the bushings has an outer rim and an open center. Flaps including a slot and having a shape configured to substantially adjustably seal the central opening are also included and a shaft is included that extends through the slots of the flaps and the open centers of the bushings.03-11-2010

Iliya Goldin, Auburn Hills, MI US

Patent application numberDescriptionPublished
20090084335SYSTEM AND METHOD FOR CONTROLLING TURBULENCE IN A COMBUSTION ENGINE - A system for controlling turbulence in a combustion engine having a composite upper intake manifold and a cylinder head. The system includes a composite housing, a composite cartridge, a shaft, a radial gasket, a lever arm, and a press in place gasket. The composite housing includes an open first end and an open second end. The open second end defines a first cross-sectional area. The first end is configured to be welded to the composite upper intake manifold and the second end has a gasket groove. The second end is configured to be connected with the cylinder head. The composite cartridge is positioned within and removably joined with the second end of the composite housing. The composite cartridge includes a body, a flap valve, and bushings. The shaft connected to the flap valve within the composite housing. The press in place gasket is positioned within the gasket groove.04-02-2009

Ilya M. Goldin, Pittsburgh, PA US

Patent application numberDescriptionPublished
20080294398Method and apparatus for the automated construction of models of activities from textual descriptions of the activities - A method of automatically constructing a model of an activity from an unsupervised examination of a plurality of textual documents describing the activity is comprised of: extracting prototypical steps from the plurality of textual documents; sequencing the extracted steps; aligning the sequenced steps; and constructing the model based on the aligned steps. The model may take the form of a step vs. position matrix which identifies the prototypical steps that make up the activity and provides the probability of each step occupying each position within the activity. The model thus constitutes common sense knowledge that encodes the stereotypical steps of an activity and the stereotypical sequencing of the steps.11-27-2008
20080294425Method and apparatus for performing semantic update and replace operations - A method of changing semantic information comprises changing a first bi-directional coupling between a surface region in a document and a first semantic object to a second bi-directional coupling between the surface region and a second semantic object. More particularly, the method may be comprised of identifying an occurrence of a surface region in a document, the surface region having a first link for coupling the surface region to a first semantic object, and the first semantic object having a first association for coupling the first semantic object with the surface region. The first link is replaced with a second link for coupling the surface region to a second semantic object. The first association is changed to a second association for coupling the second semantic object with the surface region. Another method for changing semantic information comprising selecting a semantic object stored in a data repository and changing the selected semantic object. A scope is then selected, either manually or automatically. A set of semantically anchored expressions associated with the semantic object is identified in response to the scope. A determination is made if the semantically anchored expressions are consistent with the changed semantic object and, if not, the semantically anchored expressions are updated so as to be consistent with the changed semantic object.11-27-2008
20080294426Method and apparatus for anchoring expressions based on an ontological model of semantic information - A method and apparatus for the recording and maintenance of semantic elements in electronically-held information objects provide for grounding semantic objects in an ontology, such that inheritance and other relations between concepts are preserved in persistent storage. The disclosed method and apparatus provide semantic document authors with a means to anchor concept references to specific, persistent, semantic objects, thereby providing the system with access to all properties of the underlying data model of the semantic objects being referenced, while also specifying the type and scope of their relations, as well as behavioral aspects of the visual and editing environment.11-27-2008
20080294427Method and apparatus for performing a semantically informed merge operation - A method and apparatus for performing an informed semantic merge operation comprises selecting a source region in a document and a target region in the same or a different document. A bi-directionally coupled surface region is identified in the source region and a bi-directionally coupled surface region is identified in the target region. A first semantic object coupled to the surface region in the source region is identified and a second semantic object coupled to the surface region in the target region is identified. The subcomponents of the first semantic object are combined with the subcomponents of the second semantic object by merging.11-27-2008
20080295013Method and apparatus for performing semantically informed text operations - One example of a semantically informed text operation comprises selecting a source region of a document and determining if the source region has a surface region bi-directionally coupled to a semantic object. The coupled semantic object is identified as are the presentation(s) associated with the semantic object. A target region of the same or anther document is selected. Any of the presentations that cannot be expressed in the target region are eliminated to identify a set of remaining presentations. A set of semantic choices based on the remaining presentations is determined. One of the semantic choices is selected and executed in the target region.11-27-2008

Lliya Goldin, Rochester, MI US

Patent application numberDescriptionPublished
20110303178ASSEMBLY AND METHOD FOR CONTROLLING AN AIR INTAKE RUNNER - A method of modifying an air intake manifold to control air intake runners. The method includes the steps of providing a cartridge including a plurality of compartments, each spaced apart to define a groove therebetween, snap-fitting a bushing carrier having a rotatable bushing into each of the grooves, positioning a flap having a slot over each of the compartments, inserting a shaft through each slot and each bushing thereby rotatably retaining each of the flaps within one of the plurality of compartments, positioning the cartridge over the air intake manifold so that each of the plurality of compartments is substantially axially aligned with one of the air intake runners, and removably connecting the cartridge with the air intake manifold.12-15-2011

Mark Goldin, Orlando, FL US

Patent application numberDescriptionPublished
20080294166EXTENDABLE CUTTING MEMBER - Provided is a minimally invasive cavity formation instrument for forming tissue cavities. The instrument includes an end effector having an aperture through which a cutting element is laterally extended and retracted. The cutting element may be retracted for minimally invasive insertion into a tissue region and extended to form a tissue cavity. The end effector of the instrument may be articulated or rotated to facilitate cavity formation.11-27-2008
20080294167ARTICULATING CAVITATION DEVICE - Provided is an articulating cavitation device configured to cut cancellous bone wholly within a vertebra. The articulating cavitation device includes an end effector, having an extendable cutting element, configured to articulate relative to an insertion tube. The end effector of the cavitation device may be articulated and rotated with the cutting element extended to form a tissue cavity about multiple axes.11-27-2008
20090131952DELIVERY SYSTEM AND METHOD FOR INFLATABLE DEVICES - Provided is a flowable material delivery system and method comprising one or a plurality of tentacles associated with an inflatable member. The tentacles are configured to deliver bone cement to a vertebral cavity upon reduction of a vertebral compression fracture. The tentacles may be coupled with the outer surface of an inflatable member or pass through the inflatable member to deliver a flowable material to a tissue cavity.05-21-2009

Patent applications by Mark Goldin, Orlando, FL US

Mark A. Goldin, Orlando, FL US

Patent application numberDescriptionPublished
20100049320APPARATUS AND METHODS FOR TENDON OR LIGAMENT REPAIR - Apparatus and methods for repairing damaged tendons or ligaments. Various repair apparatus include an elongate tensile member and a pair of anchor assemblies connected for movement along the tensile member on either side of a repair site, such as a tear or laceration. The anchor assemblies or structures may take many forms, and may include barbed, helical, and crimp-type anchors. In the preferred embodiments, at least one anchor structure is movable along the elongate tensile member to assist with adjusting a tendon segment to an appropriate repair position and the anchor structure or structures are then lockable onto the elongate tensile member to assist with affixing the tendon at the repair position. Tendon and/or ligament-to-bone repair apparatus and methods employ similar concepts.02-25-2010

Maxim Goldin, Redmond, WA US

Patent application numberDescriptionPublished
20110225592Contention Analysis in Multi-Threaded Software - A contention log contains data for contentions that occur during execution of a multi-threaded application, such as a timestamp of the contention, contention length, contending thread identity, contending thread call stack, and contended-for resource identity. After execution of the application ends, contention analysis data generated from the contention log shows developers information such as total number of contentions for particular resource(s), total number of contentions encountered by thread(s), a list of resources that were most contended for, a list of threads that were most contending, a plot of the number of contentions per time interval during execution of the application, and so on. A developer may pivot between details about threads and details about resources to explore relationships between thread(s) and resource(s) involved in contention(s). Other information may also be displayed, such as call stacks, program source code, and process thread ownership, for example.09-15-2011