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Goldberger, US
Ary Goldberger, Newton Center, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100191130 | METHOD FOR DETECTING PATHOLOGIES USING CARDIAC ACTIVITY DATA - The invention relates to a method for determining a pathology in a subject, said method comprising: a) correlating N-N intervals with rate dependent fluctuations of electrocardiographic parameters derived from an electrocardiogram (ECG) of said subject or other recordings reflecting cardiac activity of said subject to derive electrocardiographic parameters correlation values, wherein said pathology is determined based on said correlation values. | 07-29-2010 |
Ary L. Goldberger, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090316976 | Complexity-based analysis of cellular flickering - Provided herein are methods and systems for assessing cellular flickering. The methods include using a phase contrast microscope to obtain a plurality of images of a cell, digitizing and/or pixilating the plurality of images such that the plurality of images are segmented into an array of pixels, each pixel representing a portion of the cell, and measuring the fluctuations in the pixel intensities. The methods further include calculating a complexity measure for the individual pixels based on the measured fluctuations of the portions of the cell represented by the individual pixels. Such complexity measures can then be mapped and/or plotted in order to assess cellular flickering, and thereby assess biological function and other characteristics of the cell. | 12-24-2009 |
Ary L. Goldberger, Newton Center, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100069762 | System And Method For Assessing Sleep Quality - An assessment of sleep quality and sleep disordered breathing is determined from cardiopulmonary coupling between two physiological data series. An R-R interval series is derived from an electrocardiogram (ECG) signal. The normal beats from the R-R interval series are extracted to produce a normal-to-normal interval series. The amplitude variations in the QRS complex are used to extract a surrogate respiration signal (i.e., ECG-derived respiration) associated with the NN interval series. The two series are corrected to remove outliers, and resampled. The cross-spectral power and coherence of the two resampled signals are calculated over a plurality of coherence windows. For each coherence window, the product of the coherence and cross-spectral power is used to calculate coherent cross-power. Using the appropriate thresholds for the coherent cross-power, the proportion of sleep spent in CAP, non-CAP, and wake and/or REM are determined. Coherent cross-power can be applied to differentiate obstructive from non-obstructive disease, and admixtures of the same. | 03-18-2010 |
Bruce A. Goldberger, Newberry, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20090197283 | DEVICES AND METHODS FOR THE COLLECTION AND DETECTION OF SUBSTANCES - The present invention is a single self-contained device for collecting, transferring, extracting, and testing for the presence of a target analyte in a sample obtained from a surface by swabbing, solid materials (pills, capsules, unknown powders), air samples and biological and non-biological fluids. The device includes a swab, a retention well including eluent fluid, and analysis technologies which can include but are not limited to lateral flow testing analysis. The major improvement is the invention of rinsing the swab with proprietary elution fluid prior to testing thereby not compromising the chemistry and allowing for a wide variety of applications under extremely hot or cold field conditions. Also, the device is in one self-contained unit instead of having a separate water dropper or spray. Moreover, the shape of the device is similar to a magic marker so it is more substantial than any drug tester on the market, as well in certain embodiments it can have grips resembling a gun and in certain embodiments can even emit sounds or smells when a surface is wiped or a positive test is attained | 08-06-2009 |
| 20100129922 | DEVICES AND METHODS FOR THE COLLECTION AND DETECTION OF SUBSTANCES - The present invention provides a single self-contained device for collecting, extracting, on-site testing, and transferring for forensic confirmatory analysis, a wide variety of substances including, but not limited to, drugs of abuse, explosives, weapons of mass destruction, food toxins and industrial wastes. Samples can be obtained from a surface by swabbing a suspect area or the testing of solid materials (pills, capsules, powders), air samples and biological and non-biological fluids by placing the substance in the device. The device includes a swab, a retention well including a wash, and analysis technologies that can be, for example, a lateral flow testing system. The swab is rinsed with a wash prior to testing thereby not compromising the chemistry of the detection technologies and allowing for a wide variety of applications under a number of field conditions. Also, the device is a single self-contained unit instead of having a separate reagent droppers or sprays, making it compact and easy to use. Moreover, the device is designed to not only collect and test samples but to seal the originally target analyte, not affected by testing procedures, in a specially designed cap for shipping under chain of custody documentation to a forensic laboratory for confirmatory testing. | 05-27-2010 |
Daniel Goldberger, Boulder, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080200838 | WEARABLE, PROGRAMMABLE AUTOMATED BLOOD TESTING SYSTEM - The present invention is a programmable, automated device for measurement and analysis of blood analytes and blood parameters. The device components are preferably combined in a single housing and either programmed to initiate automatic, periodic blood sampling or initiate automatic blood sampling via operator input or in response to a predefined event or in response to a signal from another instrument. The device operates automatically to draw blood samples and analyze the drawn blood samples to obtain the desired blood readings. | 08-21-2008 |
| 20080275324 | Fluid Access Interface - The present invention relates generally to systems, apparatuses, and methods for obtaining a fluid sample from a patient. In particular, the present invention relates to a various types of fluid access interfaces for enabling contact between a patient blood sample and blood parameter sensors for the measurement of physiological parameters and blood constituents. | 11-06-2008 |
| 20090156922 | BLOOD MONITORING SYSTEM - The present invention is directed towards apparatuses and methods for the automated measurement of blood analytes and blood parameters for bedside monitoring of patient blood chemistry. Particularly, the current invention discloses a programmable system that can automatically draw blood samples at a suitable programmable time frequency (or at predetermined timing), can automatically analyze the drawn blood samples and immediately measure and display blood parameters such as glucose levels, hematocrit levels, hemoglobin blood oxygen saturation, blood gases, lactate or any other blood parameter. | 06-18-2009 |
| 20100020309 | BLOOD MONITORING SYSTEM - The present invention is directed towards apparatuses and methods for the automated measurement of blood analytes and blood parameters for bedside monitoring of patient blood chemistry. Particularly, the current invention discloses a programmable system that can automatically draw blood samples at a suitable programmable time frequency (or at predetermined timing), can automatically analyze the drawn blood samples and immediately measure and display blood parameters such as glucose levels, hematocrit levels, hemoglobin blood oxygen saturation, blood gases, lactate or any other blood parameter. | 01-28-2010 |
Daniel S. Goldberger, Boulder, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080212071 | METHOD OF DETERMINING ANALYTE CONCENTRATION IN A SAMPLE USING INFRARED TRANSMISSION DATA - A method determines an analyte concentration in a sample. The sample includes the analyte and a substance. The method includes providing absorption data of the sample. The method further includes providing reference absorption data of the substance. The method further includes calculating a substance contribution of the absorption data. The method further includes subtracting the substance contribution from the absorption data, thereby providing corrected absorption data substantially free of a contribution from the substance. | 09-04-2008 |
| 20110196266 | HANDPIECE FOR ULTRASONIC MEDICAL DEVICES - Described are embodiments including methods and devices for venting a handpiece of a medical device. These embodiments provide a vent for the handpiece. A porous membrane is positioned over an opening of the vent to allow gas, including steam, to enter and escape from the handpiece and prevent liquids from entering the handpiece. Other embodiments include methods and devices for holding an ultrasonic driver assembly within a handpiece and preventing the ultrasonic driver assembly from rotating within the handpiece. These embodiments include positioning the ultrasonic driver assembly such that the ultrasonic driver assembly is held in place at a node of the ultrasonic driver assembly and an anti-rotation mechanism is also located at the node. | 08-11-2011 |
Jeffrey Goldberger, Skokie, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20110190834 | DEVICES AND METHODS FOR SUPPRESSION OF SYMPATHOEXCITATION - The present invention relates to devices and methods for suppression of sympathoexcitation and/or sudden cardiac death. In particular the present invention provides devices and methods which prevent sympathoexcitation and/or sudden cardiac death through an elevated heart rate stimulus. | 08-04-2011 |
| 20110224962 | Electrophysiologic Testing Simulation For Medical Condition Determination - A system simulates stimulation of scar tissue identified as hyper-enhanced areas in a medical image with variable luminance thresholds and categorizes partially-viable myocardium as distinct from non-viable scar tissue. A cardiac function analysis system includes a repository of imaging data representing a 3D volume comprising a patient heart. A model processor provides a model of the patient heart using the imaging data said model being for use in allocating electrical properties to model parameters determining electrical conductivity associated with image data classified as, (a) scar tissue, (b) impaired tissue and (c) normal heart tissue. The electrical properties allocated to scar tissue are different to electrical properties allocated to normal tissue. A stimulation processor simulates electrical stimulation of the patient heart using the model to identify risk of heart impairment. | 09-15-2011 |
Josh Goldberger, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100143679 | NANOSCALE LAMELLAR PHOTOCONDUCTOR HYBRIDS AND METHODS OF MAKING SAME - An article of manufacture and methods of making same. In one embodiment, the article of manufacture has a plurality of zinc oxide layers substantially in parallel, wherein each zinc oxide layer has a thickness d | 06-10-2010 |
Joshua Goldberger, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20110233512 | VERTICAL INTEGRATED SILICON NANOWIRE FIELD EFFECT TRANSISTORS AND METHODS OF FABRICATION - Vertical integrated field effect transistor circuits and methods are described which are fabricated from Silicon, Germanium, or a combination Silicon and Germanium based on nanowires grown in place on the substrate. By way of example, vertical integrated transistors are formed from one or more nanowires which have been insulated, had a gate deposited thereon, and to which a drain is coupled to the exposed tips of one or more of the nanowires. The nanowires are preferably grown over a surface or according to a desired pattern in response to dispersing metal nanoclusters over the desired portions of the substrate. In one preferred implementation, SiCl | 09-29-2011 |
Joshua Goldberger, Berkeley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110168968 | FLUIDIC NANOTUBES AND DEVICES - Fluidic nanotube devices are described in which a hydrophilic, non-carbon nanotube, has its ends fluidly coupled to reservoirs. Source and drain contacts are connected to opposing ends of the nanotube, or within each reservoir near the opening of the nanotube. The passage of molecular species can be sensed by measuring current flow (source-drain, ionic, or combination). The tube interior can be functionalized by joining binding molecules so that different molecular species can be sensed by detecting current changes. The nanotube may be a semiconductor, wherein a tubular transistor is formed. A gate electrode can be attached between source and drain to control current flow and ionic flow. By way of example an electrophoretic array embodiment is described, integrating MEMs switches. A variety of applications are described, such as: nanopores, nanocapillary devices, nanoelectrophoretic, DNA sequence detectors, immunosensors, thermoelectric devices, photonic devices, nanoscale fluidic bioseparators, imaging devices, and so forth. | 07-14-2011 |