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Gold, CA
Adam C. Gold, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110022067 | CLAMP HAVING BENDABLE SHAFT - A clamp has a handle assembly, a gripping assembly having a pair of jaws that can be opened and closed to grip an element, and a shaft assembly. The shaft assembly has a flexible shaft having a proximal end that is operatively coupled to the handle assembly and a distal end that is operatively coupled to the gripping assembly. The shaft assembly also has a rigid element that can be placed in a first position where the rigid element supports the shaft in a manner where the shaft cannot be bent, and in a second position where the shaft can be bent. | 01-27-2011 |
Daniel Gold, South San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100184134 | DUAL CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO SYNTHESIS METHOD - This invention provides for a novel means of incorporating non-native amino acids into preselected positions of a protein using a cell-free synthesis system. The methods involve the use of non-orthogonal, native isoaccepting sense tRNAs that are encoded by the genetic code. Such methods allow for numerous non-native amino acids to be incorporated through the use of sense codons without having to rely upon orthogonal tRNA-synthetase pairs. | 07-22-2010 |
| 20100184135 | MONO CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO PROTEIN SYNTHESIS SYSTEM - This invention provides for a novel means of incorporating non-native amino acids into preselected positions of a protein using a cell-free synthesis system. The methods involve the use of non-orthogonal, native isoaccepting sense tRNAs that are encoded by the genetic code. Such methods allow for numerous non-native amino acids to be incorporated through the use of sense codons without having to rely upon orthogonal tRNA-synthetase pairs. | 07-22-2010 |
Daniel Gold, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100203587 | USE OF DNA GYRASE INHIBITORS FOR IN VITRO POLYPEPTIDE SYNTHESIS REACTIONS - The present invention provides methods and compositions useful for in vitro polypeptide synthesis reactions. The methods involve the use of DNA gyrase inhibitors to prevent bacterial contamination in lysates used for in vitro production of polypeptides. The compositions include contamination-free cell lysates for in vitro protein synthesis reactions. | 08-12-2010 |
Daniel P. Gold, Del Mar, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120114593 | METHOD AND COMPOSITION FOR ALTERING A B CELL MEDIATED PATHOLOGY - The present invention provides compositions for altering a B cell mediated pathology in a patient. The compositions may comprise at least one and/or two chimeric proteins. Each chimeric protein comprises at least a portion of either the V | 05-10-2012 |
Ezra R. Gold, Sunnyvale, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110151590 | APPARATUS AND METHOD FOR LOW-K DIELECTRIC REPAIR - A method, a system and a computer readable medium for integrated in-vacuo repair of low-k dielectric thin films damaged by etch and/or strip processing. A repair chamber is integrated onto a same platform as a plasma etch and/or strip chamber to repair a low-k dielectric thin film without breaking vacuum between the damage event and the repair event. UV radiation may be provided on the integrated etch/repair platform in any combination of before, after, or during the low-k repair treatment to increase efficacy of the repair treatment and/or stability of repair. | 06-23-2011 |
Garry E. Gold, Stanford, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090306496 | AUTOMATIC SEGMENTATION OF ARTICULAR CARTILAGE FROM MRI - A method for musculoskeletal tissue segmentation used in magnetic resonance imaging (MRI) is provided. MRI image data is collected using at least two different contrast mechanisms. Voxel values from data from each contrast mechanism are used as elements of a feature vector. The feature vector is compared with classification boundaries to classify musculoskeletal tissue type of the voxel. The previous two steps are repeated for a plurality of voxels. An image is generated from the classified musculoskeletal tissue types for the plurality of voxels to provide a musculoskeletal segmentation image. | 12-10-2009 |
| 20100033179 | DISTORTION-FREE MAGNETIC RESONANCE IMAGING NEAR METALLIC IMPLANTS - A method for 3D magnetic resonance imaging (MRI) with slice-direction distortion correction is provided. One or more selective cross-sections with a thickness along a first axis is excited using a RF pulse with a bandwidth, wherein a selective cross-section is either a selective slice or selective slab. A refocusing pulse is applied to form a spin echo. One or more 2D encoded image signals are acquired with readout along a second axis and phase encoding along a third axis. Slice-direction distortion is corrected by resolving the position by resolving the frequency offset. | 02-11-2010 |
Garry Evan Gold, Stanford, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110255760 | SYSTEMS AND METHODS FOR SYNCHRONIZED IMAGE VIEWING WITH AN IMAGE ATLAS - Certain embodiments of the present invention provide methods and systems for synchronizing a view of a patient image with an atlas image. Certain embodiments provide a method for synchronizing a patient image with an atlas image. The method includes retrieving an image atlas including at least one atlas image, registering an atlas image to a patient image and synchronizing a view of the atlas image to a view of the patient image. In certain embodiments, the method further includes registering a plurality of atlas images to a plurality of patient images. In certain embodiments, the step of synchronizing further includes synchronizing at least one of orientation, zoom level, window level and pan of the atlas image to the patient image. | 10-20-2011 |
Jeffrey J. Gold, Rancho Palos Verdes, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090150132 | METHOD AND APPARATUS FOR SIMULATING MULTIPLE GROUND STATION RANGING FOR SPACECRAFT - A spacecraft emulation system for emulating the operation of a spacecraft and the operation of a plurality of ground stations is coupled to spacecraft status and control clients that request connections to one of the plurality of simulated ground station ranging and tracking servers. The connection requests are made to a common address with a port address that is unique to a specific ground station. Separate range servers and tracking servers are instantiated for each ground station and return data specific to the ground station. The spacecraft emulation system determines ranging and tracking data for the plurality of simulated ground stations but supplies said data on a ground station by ground station basis. The status and control system transparently determines which ground station is simulated. | 06-11-2009 |
Joseph D. Gold, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080299582 | Culture System for Rapid Expansion of Human Embryonic Stem Cells - This disclosure provides an improved system for culturing human pluripotent stem cells. Traditionally, pluripotent stem cells are cultured on a layer of feeder cells (such as mouse embryonic fibroblasts) to prevent them from differentiating. In the system described here, the role of feeder cells is replaced by components added to the culture environment that support rapid proliferation without differentiation. Effective features are a suitable support structure for the cells, and an effective medium that can be added fresh to the culture without being preconditioned by another cell type. Culturing human embryonic stem cells in fresh medium according to this invention causes the cells to expand surprisingly rapidly, while retaining the ability to differentiate into cells representing all three embryonic germ layers. This new culture system allows for bulk proliferation of pPS cells for commercial production of important products for use in drug screening and human therapy. | 12-04-2008 |
| 20090047739 | Direct Differentiation Method for Making Cardiomyocytes from Human Embryonic Stem Cells - This invention provides a new procedure for generating cardiomyocyte lineage cells from embryonic stem cells for use in regenerative medicine. Differentiating by way of embryoid body formation or in serum is no longer required. Instead, the stem cells are plated onto a solid substrate, and differentiated in the presence of select factors and morphogens. After enrichment for cells with the appropriate phenotype, the cells are allowed to cluster into Cardiac Bodies™, which are remarkably homogeneous and suitable for the treatment of heart disease. | 02-19-2009 |
| 20090263835 | Genes that are Up- or Down-Regulated During Differentiation of Human Embryonic Stem Cells - Genes that are up- or down-regulated during differentiation provide important leverage by which to characterize and manipulate early-stage pluripotent stem cells. Over 35,000 unique transcripts have been amplified and sequenced from undifferentiated human embryonic stem cells, and three types of differentiated progeny. Statistical analysis of the assembled transcripts identified genes that alter expression levels as differentiation proceeds. The expression profile provides a marker system that has been used to identify particular culture components for maintaining the undifferentiated phenotype. The gene products can also be used to promote differentiation; to assess other relatively undifferentiated cells (such as cancer cells); to control gene expression; or to separate cells having desirable characteristics. Manipulation of particular genes can be used to forestall or focus the differentiation process, en route to producing a specialized homogenous cell population suitable for human therapy. | 10-22-2009 |
| 20100203633 | Culture System for Rapid Expansion of Human Embryonic Stem Cells - This disclosure provides an improved system for culturing human pluripotent stem cells. Traditionally, pluripotent stem cells are cultured on a layer of feeder cells (such as mouse embryonic fibroblasts) to prevent them from differentiating. In the system described here, the role of feeder cells is replaced by components added to the culture environment that support rapid proliferation without differentiation. Effective features are a suitable support structure for the cells, and an effective medium that can be added fresh to the culture without being preconditioned by another cell type. Culturing human embryonic stem cells in fresh medium according to this invention causes the cells to expand surprisingly rapidly, while retaining the ability to differentiate into cells representing all three embryonic germ layers. This new culture system allows for bulk proliferation of pPS cells for commercial production of important products for use in drug screening and human therapy. | 08-12-2010 |
| 20100317101 | Culture System for Rapid Expansion of Human Embryonic Stem Cells - This disclosure provides an improved system for culturing human pluripotent stem cells. Traditionally, pluripotent stem cells are cultured on a layer of feeder cells (such as mouse embryonic fibroblasts) to prevent them from differentiating. In the system described here, the role of feeder cells is replaced by components added to the culture environment that support rapid proliferation without differentiation. Effective features are a suitable support structure for the cells, and an effective medium that can be added fresh to the culture without being preconditioned by another cell type. Culturing human embryonic stem cells in fresh medium according to this invention causes the cells to expand surprisingly rapidly, while retaining the ability to differentiate into cells representing all three embryonic germ layers. This new culture system allows for bulk proliferation of pPS cells for commercial production of important products for use in drug screening and human therapy. | 12-16-2010 |
Josh Todd Gold, Newport Coast, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080256430 | AUTOMATED IMPLEMENTATION OF CHARACTERISTICS OF A NARRATIVE EVENT DEPICTION BASED ON HIGH LEVEL RULES - Systems and methods providing automated implementation of production characteristics for a narrative event, where a presentation criterion encoding the production characteristics is interpreted and selects a set of algorithms to use to implement those production characteristics, and where those algorithms implement the production characteristics for the event content representing the narrative event as a presentation criterion production collection and a presentation criterion integration specification, such that for an event depiction from the event content integrated with the presentation criterion production collection according to the presentation criterion integration specification, that event depiction reflects the production characteristics. | 10-16-2008 |
| 20090077672 | DEPICTION TRANSFORMATION WITH COMPUTER IMPLEMENTED DEPICTION INTEGRATOR - Systems and methods providing computer implemented depiction encoding production constructed from one or more depictions, where, for each of one or more depictions, an encoding collection encoding a narrative account is chosen from the depiction, and where, for each chosen encoding collection, an encoding collection is established from the chosen encoding collection, where one or more expression styles from the chosen encoding collection may be replaced with different corresponding expression styles, and where a depiction encoding is assembled from the established encoding collections, such that the narrative account encoded in the assembled depiction encoding is comprised of the narrative accounts of the chosen encoding collections. | 03-19-2009 |
Kenneth S. Gold, Bell Canyon, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110184537 | Multi-Level Controller System - The invention is a state machine having a host controller that controls a level-1 controller, wherein the level-1 controller controls the level-2 controller. The level-2 controller controls system component controllers, which in turn control system components to execute a process segment. For example, the machine includes a host controller that selects a set of states to be executed, a level-1 controller that activates the set of states in a predetermined order, wherein each state includes commands, and a level-2 controller that controls system components according to the commands. A method of executing a process includes identifying a set of states to be executed, issuing state commands that need to be issued to execute the current state in the set of states, and activating a next state only after all expected status reports have been received for the current state. | 07-28-2011 |
Kenneth Stewart Gold, Bell Canyon, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100096365 | HAND-HELD ELECTRO-DISCHARGE DEVICE - The hand-held electro-discharge machining fastener removal device of this invention brings an EDM electrode and its supporting ground pin and dielectric fluid structure to a fastener in a workpiece, such as an aircraft fuselage. The hand-held device brings the dielectric fluid, power supply, and control system structure to the fastener in a compact tool to permit EDM machining to be brought to large structures. | 04-22-2010 |
| 20110114605 | Advanced flushing for workpiece erosion - The hand-held electro-discharge device to remove boluses of material from a workpiece. In some implementations a conductive electrode and its supporting ground pin are immersed in a dielectric fluid contained in a hood or cavity near or at the electrode's distal tip an removably sealed to a conductive workpiece. A flushing inlet and outlet in fluid communication with said hood provide a flushing fluid, which may also be a dielectric fluid to remove FOD and cool. | 05-19-2011 |
Scott D. Gold, Santa Cruz, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110290691 | BEVERAGE PACKAGING CONFIGURATION AND DISPENSER - A product configuration is provided for the packaging of non-mixed beverages and dispensing configuration for mixing of a base beverage and mix beverage into a preferred single-serve mixed drink, contained in an insulated, light-shielded packaging. The product, called a “multi-beverage packaging configuration,” includes a plurality of single-serve base beverage containers, containing a first beverage which may be carbonated, with one or more multi-serve mix beverage containers, containing one or more types of beverage for separate consumption or mixing, and one or more corresponding volumetric dispensers. The volume of the mix beverage is proportionally divisible by the number of base beverages in the product configuration and by the volume of the volumetric dispenser. The ratio of mix beverage to base beverage in the mixed drink is dependent on the number of base beverages in the product configuration, and on the volume of the volumetric dispenser. | 12-01-2011 |
Steven Gold, Tiburon, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080276461 | EATING UTENSIL CAPABLE OF AUTOMATIC BITE COUNTING - An eating utensil includes a food carrier configured to convey food to a mouth, a sensor configured to sense the weight of food carried on the food carrier, a handle attached to the food carrier and configured to be engaged by a hand of an eater, an electric circuit in communication with the sensor and configured to count a bite of food in response to the weight of food carried on the food carrier, and a display device configured to display a number of bites consumed by the eater. | 11-13-2008 |