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Godwin

Antony Godwin, London GB

Patent application numberDescriptionPublished
20090176866Complexes having adjuvant activity - A complex that comprises a narrow molecular weight distribution polymer that includes units derived from an acrylic acid or a salt thereof, and (i) a substance that has pharmacological activity against a pathogenic organism, or (ii) a substance that has pharmacological activity against a cancer, or (iii) one or more agents selected from antigens and immunogens is useful in treating and/or inducing immunity to the pathogenic organism or the cancer, and for inducing immunity to the antigen or immunogen.07-09-2009
20100239517NOVEL CONJUGATED PROTEINS AND PEPTIDES - The invention provides a novel process for conjugating a polymer, especially PEG, to a protein or peptide, which comprises reacting a polymeric conjugation reagent with a protein or peptide containing a polyhistidine tag under conditions such that conjugation occurs via said polyhistidine tag. The resulting conjugates are novel. The invention further relates to novel conjugates of the general formula (I) in which one of X and X′ represents a polymer, and the other represents a hydrogen atom; each Q independently represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; or, if X′ represents a polymer, X-Q-W— together may represent an electron withdrawing group; and in addition, if X represents a polymer, X′ and electron withdrawing group W together with the interjacent atoms may form a ring; Z represents a protein or a peptide linked to A and B via respective histidine residues; A is a C09-23-2010
20110136723NOVEL REAGENTS AND METHOD FOR CONJUGATING BIOLOGICAL MOLECULES - A compound of the general formula X-[Q-W—(CH═CH)06-09-2011
20110262994NOVEL REAGENTS AND METHOD FOR CONJUGATING BIOLOGICAL MOLECULES - A compound of the general formula X-[Q-W—(CH═CH)10-27-2011

Patent applications by Antony Godwin, London GB

Antony Robert Godwin, Bristol GB

Patent application numberDescriptionPublished
20090298154Conjugated biological molecules and their preparation - Novel biologically active compounds of the general formula (I) in which one of X and X′ represents a polymer, and the other represents a hydrogen atom; each Q independently represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; or, if X′ represents a polymer, X-Q-W— together may represent an electron withdrawing group; and in addition, if X represents a polymer, X′ and electron withdrawing group W together with the interjacent atoms may form a ring; each of Z12-03-2009
20110182855CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION - Novel biologically active compounds of the general formula (I) in which one of X and X′ represents a polymer, and the other represents a hydrogen atom; each Q independently represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; or, if X′ represents a polymer, X-Q-W— together may represent an electron withdrawing group; and in addition, if X represents a polymer, X′ and electron withdrawing group W together with the interjacent atoms may form a ring; each of Z07-28-2011

Patent applications by Antony Robert Godwin, Bristol GB

Antony Robert Godwin, London GB

Patent application numberDescriptionPublished
20100119484DERIVATISATION OF BIOLOGICAL MOLECULES - The present disclosure relates to a new polymerisation process in which ethylenically unsaturated monomers are polymerised by a living radical polymerisation process in the presence of an initiator and a catalyst. Polymers produced by this new process are also thought to be novel and may be used to derivatise biological molecules to improve their efficacy as therapeutic treatments. A preferred polymer is of formula05-13-2010
20120014905CONUGATED PROTEINS AND PEPTIDES - Novel compounds of the general formula (I): in which X represents a polymer; Q represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; each of R01-19-2012

David Godwin, Ontario CA

David R. Godwin, Whitby CA

Patent application numberDescriptionPublished
20110125654Technique for Estimation of Confidence Interval for Probability of Defect Rediscovery - A present invention for estimating a confidence interval includes: receiving a dataset comprising information on software product defects found by a first customer and a second customer, the information comprising numbers of cases of software product defects found by the first customer and the second customer; determining a probability for each case of found software product defect using the frequencies and a total number of software product defects found; determining a plurality of bootstrapping draws from the cases of found software product defects in the dataset; determining an array of conditional probabilities that the first customer may find a given software product defect given that the second customer found the given software product defect, using the numbers of the cases and the probabilities corresponding to the cases in each bootstrapping draw; and determining a confidence interval for the determined plurality of arrays of conditional probabilities.05-26-2011

Harold Godwin, Orangeville CA

Patent application numberDescriptionPublished
20080210720Check Valve with a Spiral Coil Seal - A seal for a check valve for a metal molding machine. The seal is provided by the combination of a peripheral groove in an outer surface of the check valve and a helically wound core in the groove. The helically wound coil is expandable into sealing engagement with a cylindrical wall of the molding machine. The helically wound coil may be movable laterally in the groove between a melt channel open position and a melt channel closed position to open or seal the melt channel.09-04-2008

Harold Godwin, Fergus CA

Patent application numberDescriptionPublished
20090256282Multi-Material Injection Molding Apparatus and Method - A multi-material injection molding machine includes stationary and moving platens holding cores and first and second injection units for delivering first and second molding materials. The moving platen is slidable towards and away from the stationary platen. Further provided is a rotational distribution unit movable between the stationary platen and the moving platen and defining first cavities on one side and second cavities on an opposite side. The first cavities are for mating with cores to define first mold cavities and the second cavities are for mating with cores to define second mold cavities. Also provided are a rotational actuator for rotating the rotational distribution unit and a molding material delivery apparatus for delivering one or more of the first molding material to the first cavities and the second molding material to the second cavities.10-15-2009
20100183763Injection Molding Apparatus - An injection molding apparatus includes an inlet component, a plurality of nozzles, and a plurality of hoses, each of which is not heated. The hoses are connected between outlets of the inlet component and respective molding material inlets of the nozzles for conveying molding material from the inlet component to the nozzles. Hoses may also be connected between a rail plate and the nozzles for delivering cooling fluid or actuation fluid for an actuator to and from the nozzles. The nozzles may be fastened to a mold plate of the injection molding apparatus, such as by a threaded bushing. A heated insert may at least partially define the mold cavity to heat molding material in the mold cavity.07-22-2010
20100209547Valve Pin Bushing Assembly For An Injection Molding Apparatus - A valve pin bushing assembly for an injection molding apparatus. The assembly includes a bushing body for connection to a manifold, a flexible barrier having a first end that is continuously connected to the bushing body, and a valve pin continuously connected to a second end of the flexible barrier. The valve pin extends through a nozzle in a downstream direction towards a mold gate, wherein the valve pin is movable in an upstream direction and in the downstream direction for opening and closing the mold gate. The flexible barrier seals a channel of molding material from an outside space.08-19-2010
20100272849Melt Channel Geometries for an Injection Molding System - An injection molding system is disclosed that utilizes a melt channel wherein at least a portion of the melt channel has a noncircular cross-section for balancing shear in a melt stream of moldable material that flows therethrough. The noncircular cross-section of the melt channel portion may be, for e.g., capsule-shaped, extended egg-shaped, oval, teardrop-shaped, or peanut-shaped. A flow splitter is also disclosed that is positioned offset from a central axis of an upstream melt channel to protrude between inlets of respective downstream melt channels, where the upstream melt channel splits into the downstream melt channels, to thereby create a narrower inlet into one of the downstream melt channels and a wider inlet into the other of the downstream melt channels.10-28-2010

Harold Emerson Godwin, Fergus CA

Patent application numberDescriptionPublished
20110041499LOW DIFFERENTIAL TEMPERATURE ROTARY ENGINES - An engine for extracting energy from a heat source, comprising a support, a shaft rotatably coupled to the support and being rotatable in a first direction, a plurality of vessels coupled to and spaced about the shaft, a working fluid provided in the plurality of vessels, and a plurality of conduits connecting the vessels together in a circuitous fluid circuit. Each conduit has an outlet end connected to one of the plurality of vessels, an inlet end connected to another one of the plurality of vessels, and a one-way check valve configured to allow the working fluid to flow out of the one vessel via the outlet end, through the conduit and into the another vessel via the inlet end. The plurality of vessels and conduits are shaped and arranged about the shaft and the working fluid is selected so that when the one vessel is heated by the heat source the working fluid in the one vessel experiences an increase in vapour pressure causing at least part of the working fluid to flow from the one vessel into the another vessel located above the one vessel so as to produce a gravitational moment that encourages rotation of the shaft in the first direction.02-24-2011

James D. Godwin, Derby GB

Patent application numberDescriptionPublished
20120032403SEAL ASSEMBLY - A seal assembly including first and second components; a seal arranged between the first and second components to seal a secondary flow region from a primary flow region; and a second recess portion provided on a surface of the second component between the seal and the primary flow region, the second recess portion further being arranged to receive a first portion of a flow from the secondary flow region and being configured to promote a second flow feature within the second recess portion, wherein the second recess portion is set back from the surface of the second component such that a second portion of the flow from the secondary flow region bypasses the second recess portion.02-09-2012

Jason L. Godwin, Enschede NL

Patent application numberDescriptionPublished
20090292375SYSTEM AND METHOD TO FACILITATE CONFIGURATION OF A CONTROLLING DEVICE - A system and method wherein geographic data is used to configure a controlling device to control operations of a target device and/or to configure the controlling device to control tuning operations of a target device. The system additionally provides for the harmonization of controlling device configurations made on the controlling device and/or a remote computer.11-26-2009

Jeremy Godwin, Stein CH

Patent application numberDescriptionPublished
20090030053FUNGICIDAL COMPOSITIONS - The invention relates to a composition capable of controlling phytopathogenic fungi on a plant or propagation material thereof said composition comprising as active ingredients a mixture of: (A) Difenoconazole or a salt or metal complex thereof; and (B) Chlorothalonil, wherein said Difenoconazole or the salt or metal complex thereof and said Chlorothalonil are present in said composition in amounts which produce a synergistic effect. The composition of the invention is also suitable for the protection of industrial materials.01-29-2009
20100016339FUNGICIDAL COMPOUNDS AND COMPOSITIONS - The present invention relates, inter alia, to a compound having the formula (I):—wherein (R)n is selected from the group consisting of 4-Br, 4-OCH01-21-2010

Jeremy R. Godwin, Stein CH

Patent application numberDescriptionPublished
20080214397Fungicidal Compositions - A composition for control of diseases on useful plants or on propagation material thereof caused by phytopathogens, that, in addition to customary inert formulation adjuvants, comprises as active ingredient a mixture of component (A) and a synergistically effective amount of component (B), wherein component (A) is Cyprodinil; and component (B) a compound selected from compounds known for their fungicidal activity, is particularly effective in controlling or preventing fungal diseases of useful plants.09-04-2008
20110142802FUNGICIDAL COMPOSITIONS - A fungicidal composition suitable for control of disease caused by phytopathogens comprising (A) a compound of formula (I), wherein R06-16-2011

Mark R. Godwin, Berkshire GB

Patent application numberDescriptionPublished
20090083512Method and System for Finding Scrolled Regions Within a Tile Cache - In a method embodiment, a method includes periodically polling data sent to an output. The output is operable to render the data into a human-perceptible form. The method further includes determining if at least one partition of a first plurality of discrete partitions of the perdiodically polled data is substantially identical to a combination of respective portions of at least two partitions of a second plurality of discrete partitions of data recorded within a computer-readable storage.03-26-2009