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Glacet

Amaud Glacet, Gondecourt FR

Patent application number	Description	Published
20110059073	METHOD FOR TREATING INFECTIOUS DISEASE USING MONOCLONAL ANTIBODIES - The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADDC-type test, said antibodies capable of activating type III Fcγ receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunisation in Rh negative persons, in particular for haemolytic disease in a new-born baby or for uses such as idiopathic thrombocytopenic purpura (ITP).	03-10-2011

Arnaud Glacet, Gondecourt FR

Patent application number	Description	Published
20100145026	Antibody for ADCC And Inducing Cytokine Production - The invention concerns chimeric monoclonal antibodies, humanized or human produced in selected cell lines, said antibodies exhibiting high affinity for the CD16 receptor of effector cells of the immune system and hence capable of inducing high ADCC, but also the property of inducing cytokine and interleukin secretion, in particular IFNγ, which can enhance the ADCC activity of effector cells and hence be used for treating cancers and infections by pathogenic agents.	06-10-2010
20100323368	Cytokine production-inducing antibody - The invention relates to a method of measuring the activation of an effector cell belonging to the immune system, which may or may not be transformed, using a monoclonal (AcMo) or polyclonal antibody. The invention is characterised in that it consists in: bringing into contact (i) CD16 receptor-expressing cells in a reaction medium in the presence of the antibody and (ii) the antigen of said antibody, and measuring the quantity of at least one cytokine produced by the CD16 receptor-expressing cell. The invention also relates to the selection of an antibody capable of inducing the expression of cytokines and interleukins, such as IFN? or IL2 which are intended for the treatment of autoimmune and inflammatory diseases, cancers and infections by pathogens.	12-23-2010
20110052571	METHOD FOR TREATING IDIOPATHIC THROMBOCYTOPENIC PURPURA USING MONOCLONAL ANTIBODIES - The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADDC-type test, said antibodies capable of activating type III Fcγ receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunisation in Rh negative persons, in particular for haemolytic disease in a new-born baby or for uses such as idiopathic thrombocytopenic purpura (ITP).	03-03-2011
20110059072	METHOD FOR TREATING CANCER USING MONOCLONAL ANTIBODIES - The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADDC-type test, said antibodies capable of activating type III Fcγ receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunisation in Rh negative persons, in particular for haemolytic disease in a new-born baby or for uses such as idiopathic thrombocytopenic purpura (ITP).	03-10-2011

Arnaud Glacet, Clearwater, FL US

Patent application number	Description	Published
20100110567	BI-LAYER ADHESIVE FOR LENS LAMINATION - A method for laminating a film on to an optical article and a bi-layer adhesive for use in the method. The bi-layer adhesive includes a latex adhesive layer and an HMA layer sequentially disposed on the film and dried to form a solid layer of uniform thinness throughout to provide optical quality. Various types of films may be employed to provide an optical function. Following optional pre-treatment steps, the adhesives are coated on to the film. An optical hot press technique is used to deliver heat and pressure over a short period of time to form a functionally-enhanced optical article with high adhesive strength.	05-06-2010

Arnaud Glacet, St. Petersburg, FL US

Patent application number	Description	Published
20090071591	Process for Applying a Coating Film onto a Surface of a Lens Substrate - A process for applying a coated or uncoated film onto a first main surface of a lens substrate which can be implemented in a short period of time without any risk of deformation of the lens substrate and which avoids overheating of a temperature sensitive coating borne by a second main surface of the lens substrate opposite to the first main surface. The process combines a unique heating and UV as an activation step for the adhesives. Also contemplated are lenses produced by the process.	03-19-2009