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Giuliani, Siena

Andrea Giuliani, Siena IT

Patent application numberDescriptionPublished
20090053151Antibacterial peptides and analogues thereof - Antibacterial peptides and their multimeric analogues, with a wide range of action and low haemolytic activity are described. In particular, the peptide molecules exhibit a high antimicrobial activity against numerous bacterial species, with reduced cytotoxicity and a low haemolysis rate. The molecules of the invention are advantageously usable as therapeutic agents and coadjutants against infections caused by strains that are resistant to common antibiotics.02-26-2009

Marzia Giuliani, Siena IT

Patent application numberDescriptionPublished
20090285845Domains And Epitopes Of Meningococcal Protein NMB1870 - ‘NMB1870’ is a known surface protein in 11-19-2009
20100143418Immunising Against Meningococcal Serogroup Y Using Proteins - The invention uses polypeptide antigens and/or OMVs to immunize against serogroups A, C, W06-10-2010

Marzia Monica Giuliani, Siena IT

Patent application numberDescriptionPublished
20100035234VACCINE ASSAYS - The present invention is directed to methods, assays and compositions for implementing such methods and assays for assessing efficacy of individual components in multi-component vaccines and for assessing efficacy of a vaccine against a pathogen. In one aspect, the method of assessing efficacy of a vaccine against a pathogen is a quick assay that tests for an activity correlated with efficacy such as binding in an ELISA rather than requiring the time and expense of an assay that detects actual bactericidal activity. In another aspect, the method for testing the efficacy of an individual component in a multi-component vaccine includes obtaining an immune sample from a subject inoculated with the multi-component vaccine; blocking the portion of the immune sample that recognizes the individual component such as by addition of the individual component, and testing the efficacy of the immune sample to respond to the pathogen.02-11-2010
20110008279Methods and Compositions Relating to Adhesins as Adjuvants - This invention is in the field of immunology and relates to the discovery that adhesins are potent activators of dendritic cells.01-13-2011
20110020390MENINGOCOCCAL FHBP POLYPEPTIDES - fHBP is a protein in 01-27-2011
20110076300Hybrid Polypeptides Including Meningococcal fHBP Sequences - fHBP is a protein in 03-31-2011
20110104193COMBINATION NEISSERIAL COMPOSITIONS - Compositions comprising a first biological molecule from a 05-05-2011
20110166323CHIMERIC, HYBRID AND TANDEM POLYPEPTIDES OF MENINGOCOCCAL NMB1870 - NMB1870 is a protein in 07-07-2011

Patent applications by Marzia Monica Giuliani, Siena IT