Gisela
Gisela Backfisch, Dossenheim DE
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20110160176 | HETEROCYCLIC COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR - The invention relates to compounds of the formula (I) wherein n is 0, 1 or 2; G is CH | 06-30-2011 |
20120095015 | TRIAZOLE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR - The invention relates to compounds of formula (I), wherein n is 1 or 2, Ar is a C-bound 1,2,4-triazol radical which carries a radical R | 04-19-2012 |
Gisela Backfisch, Ludwigshafen DE
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20100280014 | N-PHENYL- (PIPERAZINYL OR HOMOPIPERAZINYL)-BENZENESULFONAMIDE OR BENZENESULFONYL-PHENL-(PIPERAZINE OR HOMOPIPERAZINE) COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR - The present invention relates to N-phenyl-(piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating diseases that respond to modulation of the serotonin 5-HT | 11-04-2010 |
20100292220 | BENZENESULFONANILIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR - The present invention relates to novel benzenesulfonanilide compounds of the formulae I and I′ and physiologically tolerated acid addition salts and the N-oxides thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for treating diseases that respond to modulation of the serotonin 5-HT | 11-18-2010 |
20100292221 | BENZENESULFONANILIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR - The present invention relates to novel benzenesulfonanilide compounds of the formulae I and I′ and physiologically tolerated acid addition salts and the N-oxides thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for treating diseases that respond to modulation of the serotonin 5-HT | 11-18-2010 |
20110059968 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS - The present invention relates to novel carboxamide compounds of the formula I and their use for the manufacture of a medicament. The carboxamide compounds are prodrugs of inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. | 03-10-2011 |
20110152265 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V - The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. | 06-23-2011 |
20110152325 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS IV - The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. | 06-23-2011 |
20120040969 | N-PHENYL-(PIPERAZINYL OR HOMOPIPERAZINYL)-BENZENESULFONAMIDE OR BENZENESULFONYL-PHENYL-(PIPERAZINE OR HOMOPIPERAZINE) COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR - The present invention relates to N-phenyl-(piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating diseases that respond to modulation of the serotonin 5-HT | 02-16-2012 |
20130018047 | N-PHENYL-(PIPERAZINYL OR HOMOPIPERAZINYL)-BENZENESULFONAMIDE OR BENZENESULFONYL-PHENYL-(PIPERAZINE OR HOMOPIPERAZINE) COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR - The present invention relates to N-phenyl-(piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compounds, pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating diseases that respond to modulation of the serotonin 5-HT | 01-17-2013 |
20140005227 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V | 01-02-2014 |
Gisela Backfisch, Wiesbaden DE
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20140179702 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS IV - The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. | 06-26-2014 |
20150065477 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V - The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula (I) in which R | 03-05-2015 |
Gisela Barbany, Uppsala SE
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20100099082 | Allele Detection - Method for simultaneously determining alleles present in a set of loci from at least one nucleic acid sample comprising the steps: a) providing said at least one sample, b) subjecting said sample to a nucleic acid amplification reaction using a primer pair simultaneously primer pairs specific and optimized for each of the loci of a set of at least three loci selected from the group consisting of D2S1360, D7S1517, D8S1132, D9S1118, D10S2325, D11S554, D12S1064, D12S391, D17S1290, D19S253, MYCLl, P450CYP19 and SE-33, and c) evaluating the length and optionally the relative quantity of amplification products obtained from step b) or from the analysis of one or two of the above loci to determine and/or optionally quantify the alleles present at each of the loci analyzed in the set within said sample. | 04-22-2010 |
Gisela Bengtson, Hamburg DE
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20090029849 | IMMOBILIZED HOMOGENEOUS CATALYSTS - A catalyst is produced by bonding a homogeneous catalyst to the surface of a catalyst support. A catalyst may include a catalyst support, a spacer molecule bonded to the catalyst support, and a homogeneous catalyst bonded to the spacer molecule. A catalyzed reaction can be carried out by providing reactants in a first phase and providing a catalyst as described herein in the first phase. | 01-29-2009 |
Gisela Bruenagel, Pittsburgh, PA US
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20080248496 | NUCLEAR MATRIX PROTEIN ALTERATIONS ASSOCIATED WITH COLON CANCER AND COLON METASTASIS TO THE LIVER, AND USES THEREOF - Proteins useful in the diagnosis of proliferative disorders of the colon are present in nuclear matrix protein preparations and can be characterized by molecular weight, isoelectric point, and amino acid sequence. The proteins may be identified, for example, by 2D-gel electrophoresis or by specific binding partners, such as antibodies. | 10-09-2008 |
Gisela Eberle-Rubo, Baden-Baden DE
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20100032024 | BEVERAGE CONTAINER TAPPING APPARATUS - The invention relates to a beverage container tapping apparatus, with: | 02-11-2010 |
Gisela Fuchs, Rosstal DE
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20150129738 | ADJUSTMENT DEVICE FOR A PIVOTABLE CARRIER PLATE, PARTICULARLY FOR RECEIVING A MOTOR VEHICLE MIRROR - An adjustment device for a carrier plate which can be pivoted about two mutually orthogonal axes and is configured to receive a motor vehicle mirror, includes one motor per axis for moving a non-rotatably and non-tiltably guided linear drive, which is in engagement via a socket with a joint ball on the carrier plate, and a funnel-shaped hub provided with a hollow shaft. A hollow spherical segment of the funnel-shaped hub engages, by spring tabs, in a depression in the form of a hollow spherical segment in the carrier plate, and a spherical segment of the carrier plate is axially elastically clamped in a hollow spherical segment of a housing for drive trains of the two linear drives, thereby locking the hollow shaft on the housing. | 05-14-2015 |
Gisela Goldhalm, Neufurth AT
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20140315461 | CELLULOSIC FIBER WITH HYDROPHOBIC PROPERTIES AND HIGH SOFTNESS AND PROCESS FOR PRODUCTION THEREOF - The invention refers to hydrophobic cellulose fibers which are biodegradable, extra soft and water repellent. Nonwovens comprising the inventive cellulosic fibers show also higher softness. Said fibers add bulk, better drape ability and hydrophobicity to nonwoven fabrics which are biodegradable if made only from Cellulosic fibers. | 10-23-2014 |
Gisela Günzel, Ostercappeln DE
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20090311515 | Layer Support for Recording Materials - A support material for recording layers comprising a raw base paper contains a hardwood pulp having a fibre fraction smaller than 200 μm, after refining, of at most 45 wt. % and an average fibre length of 0.4 to 0.8 mm and a filler fraction of 5 to 40 wt. %, in particular 10 to 25 wt. %, relative to the mass of the pulp. | 12-17-2009 |
Gisela Günzel, Ostercappeln DE
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20090311515 | Layer Support for Recording Materials - A support material for recording layers comprising a raw base paper contains a hardwood pulp having a fibre fraction smaller than 200 μm, after refining, of at most 45 wt. % and an average fibre length of 0.4 to 0.8 mm and a filler fraction of 5 to 40 wt. %, in particular 10 to 25 wt. %, relative to the mass of the pulp. | 12-17-2009 |
Gisela Guthausen, Rheinstetten DE
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20110204894 | Analysis system with GPC and NMR spectroscopy coupling, in particular for the analysis of samples having polymers - An analysis system ( | 08-25-2011 |
Gisela Hahn, Alveslohe DE
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20080300283 | Microbicidal preparations based on 1, 2-benzisothiazonlin-3-one with a content of aromatic alcohol - The invention relates to microbicidal preparations which comprise a) at least one of 1,2-benzisothiazolin-3-one and its derivatives, b) at least one of 2-mercaptopyridine N-oxide, its salts and derivatives, c) at least one aromatic alcohol and d) at least one alkalinizing agent, or which are prepared by mixing components a) to d), where the preparations have a pH of at least 11. The preparations are characterized by the fact that they are clear and storage-stable, and they are suitable for use as preservatives. | 12-04-2008 |
20090123577 | LIQUID CONCENTRATE FOR PRESERVING COSMETICS - The invention relates to a liquid concentrate for preserving cosmetic products which comprises a combination of carboxylic acid salts chosen from the salts of benzoic acid, propionic acid, salicylic acid, sorbic acid, 4-hydroxybenzoic acid, dehydracetic acid, formic acid or 10-undecylenic acid and alcohols chosen from 2-phenoxyethanol, benzyl alcohol, phenethyl alcohol, 1-phenoxypropan-2-ol, 3-(4-chlorophenoxy)-1,2-propanediol, chlorobutanol or 2,4-dichlorobenzyl alcohol in a solvent, where the active ingredient content is greater than 45% by weight. | 05-14-2009 |
20120232168 | LIQUID CONCENTRATE FOR PRESERVING COSMETICS - A liquid concentrate for preserving cosmetic products which includes a combination of carboxylic component being sodium benzoate and an alcohol component being a mixture of phenoxy ethanol and benzyl alcohol, in a water, where the combination is greater than 45% by weight of the liquid concentrate. | 09-13-2012 |
Gisela Jung, Wiesbaden DE
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20140284267 | ABRASION-PROOF FILTRATION MEMBRANE AND METHOD OF PRODUCING SAID MEMBRANE - A filtration membrane ( | 09-25-2014 |
Gisela Kaltenpoth, Eschborn DE
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20080245798 | Device for Comprising a Releasable Latch Connection - Disclosed is a device comprising a base part ( | 10-09-2008 |
Gisela Peraus, Loerrach DE
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20100168144 | INHIBITORS OF PROTEIN KINASES - The present invention relates to inhibitors of cyclin-dependent kinases and therapeutic applications thereof. Furthermore, the invention relates to methods of preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases comprising the administration of an effective amount of at least one inhibitor of cyclin-dependent kinases. formula (I). | 07-01-2010 |
20100184780 | INHIBITORS OF PROTEIN KINASES - The present invention provides new compounds. The compounds are useful as CDK5 inhibitors, and accordingly they can be included in pharmaceuticals compositions for treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases. formula (I). | 07-22-2010 |
20130331407 | INHIBITORS OF PROTEIN KINASES - The present invention relates to inhibitors of cyclin-dependent kinases and therapeutic applications thereof. Furthermore, the invention relates to methods of preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases comprising the administration of an effective amount of at least one inhibitor of cyclin-dependent kinases. | 12-12-2013 |
Gisela Peraus, Munich DE
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20080275063 | Inhibitors of protein kinases - The present invention provides new compounds. The compounds are useful as CDK5 inhibitors, and accordingly they can be included in pharmaceutical compositions for treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases. | 11-06-2008 |
Gisela Perez Gesteira, Sao Paulo BR
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20130193614 | USE OF POLYAMIDE FOR THE PREPARATION OF INJECTION-MOLDED ARTICLES AND RESULTING ARTICLES - The use of thermoplastic polymers for the preparation of injection-molded articles and the resulting articles are described. Also described, is the use of a lubricated polyamide, obtained by means of the addition of at least one lubricant during the polyamide polymerization method, for the preparation of injection-molded articles. | 08-01-2013 |
Gisela Perruna, Rahway, NJ US
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20110240050 | COSMETIC COMPOSITIONS CONTAINING A FATTY ACID, ARGININE, AND A CO-EMULSIFIER - Disclosed are cosmetic compositions containing a fatty acid, arginine, and a co-emulsifier. Also disclosed are methods for making the cosmetic composition and applying it to keratinous tissue such as skin in order to enhance its appearance. | 10-06-2011 |
20110306679 | COMPOSITIONS CONTAINING AGAR AND A SOFTENING AGENT - The present invention includes a composition that has (a) at least one thermo-reversible polysaccharide chosen from agar; (b) at least one softening agent chosen from a cationic surfactant, an anionic surfactant, a nonionic esterified sugar surfactant, a polyorganosiloxane-containing polymer, a sugar silicone surfactant, and mixtures thereof; (c) at least one oil; and (d) water. | 12-15-2011 |
20110306680 | COMPOSITIONS CONTAINING AGAR AND ESTERIFIED SUGAR SURFACTANTS - The present invention is directed to a composition that includes (a) at least one thermo-reversible polysaccharide chosen from agar; (b) at least one softening agent chosen from an esterified sugar surfactant; (c) at least one oil; (d) water; and (e) optionally, at least one emulsifier different from (b), as well as to processes for softening an emulsion containing agar by adding to the emulsion at least one softening agent chosen from an esterified sugar surfactant. | 12-15-2011 |
20120237463 | COSMETIC EMULSIONS CONTAINING UNCOATED SILICONE ELASTOMERS AND NON SILICONE TREATED PIGMENTS - Disclosed are cosmetic compositions in the form of an emulsion that contain an uncoated silicone elastomer, a solvent for the elastomer, a non-silicone treated pigment and an emulsifier, methods of making the compositions, and methods of applying the compositions to a keratinous substrate or tissue. | 09-20-2012 |
20130302385 | COMPOSITIONS CONTAINING A WATER-BASED GEL AND A WATER-IN-OIL EMULSION - The invention relates to a composition, especially a cosmetic composition, containing (a) a water-based gel phase; and (b) a water-in-oil emulsion phase. | 11-14-2013 |
Gisela Schammler, Dresden DE
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20110189831 | REDUCING CONTAMINATION IN A PROCESS FLOW OF FORMING A CHANNEL SEMICONDUCTOR ALLOY IN A SEMICONDUCTOR DEVICE - In sophisticated approaches for forming high-k metal gate electrode structures in an early manufacturing stage, a threshold adjusting semiconductor alloy may be deposited on the basis of a selective epitaxial growth process without affecting the back side of the substrates. Consequently, any negative effects, such as contamination of substrates and process tools, reduced surface quality of the back side and the like, may be suppressed or reduced by providing a mask material and preserving the material at least during the selective epitaxial growth process. | 08-04-2011 |
20120009751 | REDUCING CONTAMINATION IN A PROCESS FLOW OF FORMING A CHANNEL SEMICONDUCTOR ALLOY IN A SEMICONDUCTOR DEVICE - In sophisticated approaches for forming high-k metal gate electrode structures in an early manufacturing stage, a threshold adjusting semiconductor alloy may be deposited on the basis of a selective epitaxial growth process without affecting the back side of the substrates. Consequently, any negative effects, such as contamination of substrates and process tools, reduced surface quality of the back side and the like, may be suppressed or reduced by providing a mask material and preserving the material at least during the selective epitaxial growth process. | 01-12-2012 |
Gisela Schleicht, Schwabbruck DE
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20120073282 | HYDRAULIC SYSTEM - A hydraulic system, especially in a high-pressure application, comprises a pressurized-fluid tank, a pressurized-fluid pump driven by a drive unit, at least one hydraulic load that can be pressurized thereby and a control and/or distribution unit connected fluidically between the pressurized-fluid pump and the load. This unit is provided with a housing and a core received therein and connected rigidly with the housing, which core bears with part of its surface in the region of a common, closed, especially cylindrical joint face with the housing on a corresponding inside face of a housing opening. Surface groove-like flow ducts are provided on the core and/or the housing in the region of the joint face, and the pressurized-fluid pump is directly built onto the control and/or distribution unit in the region of a free end face of the core. | 03-29-2012 |
Gisela Thummler, Dresden DE
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20110178249 | USE OF POLYORGANOSILOXANES IN THE PROCESSING AND VULCANIZATION OF RUBBER - The invention relates to the use of polyorganosiloxanes having 3 or more siloxane units, which has (i) at least one organic component R | 07-21-2011 |
Gisela Ucke-Krueger, Velpke DE
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20080282488 | Washing Device - A washing device ( | 11-20-2008 |
Gisela Von Blanckenhagen, Aalen DE
Gisela Wagner, Much DE
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20110271798 | SCREW TENSIONING DEVICE - The screw tensioning device comprises a support tube ( | 11-10-2011 |
Gisela Walgenbach-Brunagel, Bonn DE
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20130344486 | METHOD OF DIAGNOSING BREAST CARCINOMA - The present invention relates to methods of diagnosing a breast carcinoma, determining the prognosis of a patient diagnosed with breast carcinoma and determining the efficacy of a treatment regimen of breast carcinoma in a patient, using Calponin-h2 and/or CALML 5 as markers. Furthermore, the invention relates to a kit and a marker panel for use in these methods. | 12-26-2013 |